المؤلفون: Naziha Bakouh, Dominique Eladari, Maxime Louet, Maria A. Miteva, Bruno O. Villoutreix, Yohan Bignon, Gabrielle Planelles, Jacques Teulon, Sara Bitam, David Lagorce

المساهمون: Molécules Thérapeutiques in silico (MTI), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche des Cordeliers (CRC), Université Paris Diderot - Paris 7 (UPD7)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Diabète athérothrombose et thérapies Réunion Océan Indien (DéTROI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de La Réunion (UR), Service d’Explorations Fonctionnelles Rénales, Centre hospitalier Félix-Guyon [Saint-Denis, La Réunion], HAL UPMC, Gestionnaire, Université Pierre et Marie Curie - Paris 6 (UPMC)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Molécules Thérapeutique in silico, Recherche de molécules à visée thérapeutique par approches In Silico ( MTI ), Université Paris Diderot - Paris 7 ( UPD7 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Centre de Recherche des Cordeliers ( CRC ), Université Paris Diderot - Paris 7 ( UPD7 ) -École pratique des hautes études ( EPHE ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Diabète athérothrombose et thérapies Réunion Océan Indien ( DéTROI ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université de la Réunion ( UR ), CHU Félix Guyon, Université Pierre et Marie Curie - Paris 6 (UPMC)-École Pratique des Hautes Études (EPHE)

المصدر: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7, pp.7249. ⟨10.1038/s41598-017-07794-5⟩
Scientific Reports, 2017, 7, pp.7249. ⟨10.1038/s41598-017-07794-5⟩
Scientific Reports, Nature Publishing Group, 2017, 7, pp.7249. 〈10.1038/s41598-017-07794-5〉
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Quantitative structure–activity relationship, [SDV.BBM.BS] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Protein Conformation, Science, [CHIM.THER] Chemical Sciences/Medicinal Chemistry, In silico, Drug Evaluation, Preclinical, Quantitative Structure-Activity Relationship, Computational biology, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, Pharmacology, Bartter syndrome, Article, Membrane Potentials, 03 medical and health sciences, Protein structure, Chlorides, Chloride Channels, medicine, Animals, Humans, Amino Acid Sequence, Membrane potential, Virtual screening, Multidisciplinary, Molecular Structure, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Chemistry, [ CHIM.THER ] Chemical Sciences/Medicinal Chemistry, medicine.disease, 3. Good health, Drug repositioning, 030104 developmental biology, Mutation, Chloride channel, Medicine, Cattle, Disease Susceptibility, Ion Channel Gating, [ SDV.BBM.BS ] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc71b54f23fb0454d678dbf974777f4Test
https://hal.sorbonne-universite.fr/hal-01580157/file/s41598-017-07794-5.pdfTest

المؤلفون: Pablo Carbonell, Gautier Moroy, Bruno O. Villoutreix, Maria A. Miteva, David Lagorce, Virginie Y. Martiny

المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e73587 (2013)

مصطلحات موضوعية: Models, Molecular, Quantitative structure–activity relationship, In silico, Science, Quantitative Structure-Activity Relationship, Computational biology, Molecular Dynamics Simulation, Bioinformatics, Crystallography, X-Ray, Ligands, 01 natural sciences, Xenobiotics, Small Molecule Libraries, 03 medical and health sciences, 0103 physical sciences, Humans, Computer Simulation, Binding site, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Binding Sites, 010304 chemical physics, Molecular Structure, Chemistry, Ligand (biochemistry), Small molecule, Arylsulfotransferase, 3. Good health, Protein Structure, Tertiary, Docking (molecular), Medicine, Thermodynamics, Small molecule binding, Sulfotransferases, Research Article, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df34ff7e23334479f964e7ad71caccb9Test
http://europepmc.org/articles/PMC3765257Test

المؤلفون: Christelle Reynes, Bruno O. Villoutreix, Philippe Vayer, Florent Chevillard, David Lagorce, Maria A. Miteva

المصدر: Molecular pharmaceutics. 9(11)

مصطلحات موضوعية: Molecular Structure, Chemistry, In silico, Reliability (computer networking), Pharmaceutical Science, Quantitative Structure-Activity Relationship, Water, Chemical similarity, Bioinformatics, computer.software_genre, Random forest, Data set, Models, Chemical, Pharmaceutical Preparations, Solubility, Test set, Drug Discovery, Molecular Medicine, Computer Simulation, Data mining, computer, Protocol (object-oriented programming), Software

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edf7fed619cef10b7ec40785aeb6827Test
https://pubmed.ncbi.nlm.nih.gov/23072744Test

المؤلفون: Pierre Martineau, Guillaume Laconde, Maria A. Miteva, Piona Dariavach, David Lagorce, Bruno O. Villoutreix

المساهمون: Molécules Thérapeutiques in silico (MTI), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de recherche en cancérologie de Montpellier (IRCM - U896 Inserm - UM1), Université Montpellier 1 (UM1)-CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Le Ster, Yves, CRLCC Val d'Aurelle - Paul Lamarque-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 1 (UM1)

المصدر: PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (6), pp.e21117. ⟨10.1371/journal.pone.0021117⟩
PLoS ONE, Vol 6, Iss 6, p e21117 (2011)

مصطلحات موضوعية: [SDV.IMM] Life Sciences [q-bio]/Immunology, Immunology, Drug Evaluation, Preclinical, Syk, lcsh:Medicine, Biology, Models, Biological, 03 medical and health sciences, 0302 clinical medicine, In vivo, Cell Line, Tumor, Drug Discovery, Anti-Allergic Agents, Animals, Syk Kinase, Mast Cells, Enzyme Inhibitors, lcsh:Science, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Molecular Structure, Drug discovery, Kinase, Allergy and Hypersensitivity, lcsh:R, Intracellular Signaling Peptides and Proteins, Computational Biology, Biological activity, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, Protein-Tyrosine Kinases, Small molecule, In vitro, 3. Good health, Rats, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Biochemistry, 030220 oncology & carcinogenesis, [SDV.IMM]Life Sciences [q-bio]/Immunology, lcsh:Q, Tyrosine kinase, Research Article, Biotechnology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3125f2fa9b7f92f8f7768022cdb9942fTest
http://europepmc.org/articles/PMC3118801Test

المؤلفون: Nicolas Renault, Bruno O. Villoutreix, Maria A. Miteva, Matthieu Montes, David Lagorce, Olivier Sperandio

المصدر: ResearcherID

مصطلحات موضوعية: Computer science, In silico, Druggability, Quantitative Structure-Activity Relationship, Nanotechnology, Ligands, Biochemistry, Structural bioinformatics, Databases, Genetic, Macromolecular docking, Databases, Protein, Molecular Biology, Information Services, Internet, Binding Sites, Molecular Structure, business.industry, Drug discovery, Computational Biology, Cell Biology, General Medicine, Data science, Docking (molecular), Cheminformatics, Drug Design, Computer-Aided Design, The Internet, business, Algorithms, Software

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9828e1eb097cc4d2c13c4a6e807ae8Test
https://pubmed.ncbi.nlm.nih.gov/17696871Test