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المؤلفون: Thomas Lund Koch, Joshua P. Torres, Robert P. Baskin, Paula Flórez Salcedo, Kevin Chase, Baldomero M. Olivera, Helena Safavi-Hemami
مصطلحات موضوعية: Molecular Biology, Neuroscience, Structural Biology, Central Nervous System, Molecular Evolution, Molecular Medicine, toxins, venom, neuropeptide, hormone, Conus, crustacean hyperglycemic hormone
الإتاحة: https://doi.org/10.3389/fnmol.2023.1176662.s003Test
https://figshare.com/articles/dataset/Data_Sheet_11_A_toxin-based_approach_to_neuropeptide_and_peptide_hormone_discovery_FASTA/24063000Test -
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المؤلفون: Shuang Ju, Yu Zhang, Xijun Guo, Qinghui Yan, Siyi Liu, Bokai Ma, Mei Zhang, Jiaolin Bao, Sulan Luo, Ying Fu
المصدر: Molecules; Volume 27; Issue 19; Pages: 6609
مصطلحات موضوعية: anti-ovarian cancer, disulfide connectivity, disulfide-rich conotoxins, voltage-gated sodium channel, Conus venom, Chemistry (miscellaneous), Organic Chemistry, Drug Discovery, Molecular Medicine, Pharmaceutical Science, Physical and Theoretical Chemistry, Analytical Chemistry
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cd352f241a657fa5e007f93c7d0156Test
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المؤلفون: Qiuyuan Huang, Xin Chu, Haoran Zhang, Shuo Yu, Longxiao Zhang, Xuerong Zhang, Rilei Yu, Chenyun Guo, Qiuyun Dai
المصدر: ACS chemical biology. 17(9)
مصطلحات موضوعية: Conus Snail, Molecular Medicine, Animals, General Medicine, Amino Acid Sequence, Disulfides, Nicotinic Antagonists, Amino Acids, Receptors, Nicotinic, Conotoxins, Biochemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa00aee37a75f52dd277e65b6b4b0e2Test
https://pubmed.ncbi.nlm.nih.gov/36048451Test -
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المصدر: Molecules; Volume 27; Issue 23; Pages: 8617
مصطلحات موضوعية: Analgesics, Organic Chemistry, Conus Snail, Pharmaceutical Science, Receptors, Nicotinic, Analytical Chemistry, analgesic conotoxin, Lv32.1, Conus lividus, α9α10 nAChR, Nav1.8 channel, Mice, Chemistry (miscellaneous), Drug Discovery, Animals, Molecular Medicine, Disulfides, Physical and Theoretical Chemistry, Conotoxins
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21f8e4ca5ba17ec4ee42cc7e8f052e4Test
https://doi.org/10.3390/molecules27238617Test -
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المؤلفون: J. Michael McIntosh, Baldomero M. Olivera, Fernando Fisher, Peter N. Huynh, Cheryl Dowell, Joanna Gajewiak, Fuaad Hararah, Sean Christensen
المصدر: J Med Chem
مصطلحات موضوعية: Peptide, Nicotinic Antagonists, Receptors, Nicotinic, Pharmacology, complex mixtures, 01 natural sciences, Article, Structure-Activity Relationship, 03 medical and health sciences, Drug Development, Drug Discovery, Conus, medicine, Humans, Receptor, Neuropharmacology, 030304 developmental biology, Acetylcholine receptor, chemistry.chemical_classification, Analgesics, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Penicillamine, biology.organism_classification, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Nicotinic agonist, Opioid, Neuralgia, Molecular Medicine, Conotoxins, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3609bed773a9c06eb7a94415ae1753Test
https://doi.org/10.1021/acs.jmedchem.1c00512Test -
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المؤلفون: Shrinivasan Raghuraman, Joshua P. Torres, Baldomero M. Olivera, Ronald W. Hughen, Manju Karthikeyan, Chang-Shan Niu, Kevin Chase, Zhenjian Lin, Alan R. Light, Marco Bortolato, Jie Zhang, Lee S. Leavitt, Lili Sun, Noemi D. Paguigan, Roberto Cadeddu, Eric W. Schmidt, Christopher A. Reilly
المصدر: Journal of Medicinal Chemistry. 64:7033-7043
مصطلحات موضوعية: 0303 health sciences, Allosteric modulator, Neuroactive steroid, Hypobranchial gland, Conus geographus, biology, Chemistry, Protein subunit, Pharmacology, biology.organism_classification, 01 natural sciences, Aminobutyric acid, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, medicine.anatomical_structure, Dorsal root ganglion, Drug Discovery, medicine, Molecular Medicine, Receptor, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2f437c0478240b76162c4f0bb243a92bTest
https://doi.org/10.1021/acs.jmedchem.1c00562Test -
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المؤلفون: Kevin Chase, Helena Safavi-Hemami, Joanna Gajewiak, Shrinivasan Raghuraman, Paula Flórez Salcedo, Cristoval Urcino, Randall T. Peterson, Baldomero M. Olivera, Samuel S. Espino, Maren Watkins, Sabrina Kozel, Gabriel D. Bossé, April Cabang
المصدر: Journal of Natural Products. 84:1232-1243
مصطلحات موضوعية: Pharmacology, Conus episcopatus, biology, 010405 organic chemistry, Bioactive molecules, fungi, Organic Chemistry, Pharmaceutical Science, Computational biology, biology.organism_classification, 01 natural sciences, In vitro, 0104 chemical sciences, Analytical Chemistry, Cone snail, Conorfamide, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, In vivo, Drug Discovery, Zebrafish larvae, Molecular Medicine, Conotoxin
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b8f13c0d166f38b24df6321bf3816d6aTest
https://doi.org/10.1021/acs.jnatprod.0c01297Test -
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المؤلفون: Sandeep Chhabra, Simon G. Gooding, Alessia Belgi, Raymond S. Norton, David J. Adams, Samuel D. Robinson, James Burnley, Peter Bartels, Fei Yue Zhao, David Spanswick, Andrea J. Robinson, Khaled A. Elnahriry, Mahsa Sadeghi, Han-Shen Tae, Christopher A. MacRaild, Haifeng Wei
المصدر: Journal of Medicinal Chemistry. 64:3222-3233
مصطلحات موضوعية: Male, Models, Molecular, Agonist, medicine.drug_class, Xenopus, Alkyne, GABAB receptor, 01 natural sciences, Rats, Sprague-Dawley, 03 medical and health sciences, Dorsal root ganglion, Drug Discovery, medicine, Alkyne metathesis, Animals, Humans, Cells, Cultured, 030304 developmental biology, chemistry.chemical_classification, Analgesics, 0303 health sciences, biology, Chemistry, HEK 293 cells, Conus Snail, biology.organism_classification, 0104 chemical sciences, Disease Models, Animal, 010404 medicinal & biomolecular chemistry, HEK293 Cells, medicine.anatomical_structure, nervous system, Hyperalgesia, Alkynes, Neuropathic pain, Biophysics, Neuralgia, Molecular Medicine, Female, Conotoxins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e7ff4e2677bf08f7477ed2e2896f72Test
https://doi.org/10.1021/acs.jmedchem.0c02151Test -
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المؤلفون: Yun Wu, Kunmei Liu, Lei Wang, Boyao Zhao, Zhao Di, Lianxiang Zhang, Jianguo Niu, Yuanyuan Qiang, Feng Wang
المصدر: International Journal of Peptide Research and Therapeutics. 27:615-625
مصطلحات موضوعية: Signal peptide, biology, Chemistry, Analgesic, Bioengineering, Conus striatus, biology.organism_classification, Biochemistry, Analytical Chemistry, Affinity chromatography, Sephadex, Drug Discovery, Molecular Medicine, Conotoxin, Peptide sequence, Cysteine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ccbb0f3ad84d679fbb37fdf39df37625Test
https://doi.org/10.1007/s10989-020-10109-4Test -
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المؤلفون: Haiping Fan, Lei Zheng, Binghua Wu, Zeyin Lin, Jiawei Yu, Mengxue Chen, Miao Ying
المصدر: Biotechnology and applied biochemistryREFERENCES. 69(4)
مصطلحات موضوعية: Biomedical Engineering, Bioengineering, Applied Microbiology and Biotechnology, Pichia, Pichia pastoris, law.invention, Green fluorescent protein, Cell surface receptor, law, Drug Discovery, Conus, Animals, Humans, Conotoxin, biology, Chemistry, Cell growth, Process Chemistry and Technology, Conus Snail, General Medicine, biology.organism_classification, HEK293 Cells, Biochemistry, Cell culture, Saccharomycetales, Recombinant DNA, Molecular Medicine, Conotoxins, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f91d47351bdf8eec4f099ba91d7a31Test
https://pubmed.ncbi.nlm.nih.gov/34337794Test