يعرض 1 - 2 نتائج من 2 نتيجة بحث عن '"Matucci, R"', وقت الاستعلام: 0.66s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents

    المؤلفون: Di Capua A., Reale A., Paolino M., Chemi G., Brogi S., Cappelli A., Giorgi G., Grande F., Di Cesare Mannelli L., Ghelardini C., Matucci R., Garofalo A., Anzini M.

    المساهمون: Di Capua, A., Reale, A., Paolino, M., Chemi, G., Brogi, S., Cappelli, A., Giorgi, G., Grande, F., Di Cesare Mannelli, L., Ghelardini, C., Matucci, R., Garofalo, A., Anzini, M.

    مصطلحات موضوعية: Anxiolytic agent, Benzodiazepine, CBR, Molecular modelling, Synthesi, Animal, Anti-Anxiety Agent, Anticonvulsant, Binding Site, Locomotion, Memory Disorder, Mice, Molecular Docking Simulation, Rat, Receptors, GABA-A, Drug Design

    العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000546723400013; volume:200; firstpage:112405; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11563/162897Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85085545341

    الإتاحة: https://doi.org/10.1016/j.ejmech.2020.112405Test
    https://hdl.handle.net/11563/162897Test

    View record in BASE

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  2. 2
    Playing with opening and closing of heterocycles: using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and P-glycoprotein inhibitors

    المؤلفون: Simona Saponara, Massimo Baroni, Domenico Spinelli, Barbara Cosimelli, Elda Severi, Pierfranco Ioan, Camillo Rosano, Roberta Budriesi, Fabio Fusi, Rosanna Matucci, Emanuele Carosati, Simon Cross, Maria Frosini, Maurizio Viale, Alberto Chiarini, Matteo Micucci

    المساهمون: Spinelli, D., Budriesi, R., Cosimelli, B., Severi, E., Micucci, M., Baroni, M., Fusi, F., Ioan, P., Cross, S., Frosini, M., Saponara, S., Matucci, R., Rosano, C., Viale, M., Chiarini, A., Carosati, E., Domenico, Spinelli, Roberta, Budriesi, Cosimelli, Barbara, Elda, Severi, Matteo, Micucci, Massimo, Baroni, Fabio, Fusi, Pierfranco, Ioan, Simon, Cro, Maria, Frosini, Simona, Saponara, Rosanna, Matucci, Camillo, Rosano, Maurizio, Viale, Alberto, Chiarini, Emanuele, Carosati

    المصدر: Molecules, Vol 19, Iss 10, Pp 16543-16572 (2014)
    Molecules
    Volume 19
    Issue 10
    Pages 16543-16572

    مصطلحات موضوعية: oxadiazolothiazinones, Pharmaceutical Science, Quantitative Structure-Activity Relationship, Multidrug resistance, ternary complex, Analytical Chemistry, Heterocyclic Compounds, Drug Discovery, Ternary complex, L-type calcium channel, Oxadiazoles, Chemistry, Calcium Channel Blockers, Molecular Docking Simulation, Subfamily B, Chemistry (miscellaneous), docking, Molecular Medicine, ATP Binding Cassette Transporter, Subfamily B, Animals, Guinea Pigs, Heart Atria, Muscle, Smooth, Structural Homology, Protein, Muscle, Smooth, Pharmacophore, structure-activity relationship, L-type calcium channels, oxadiazolothiazinone, P-glycoprotein, Quantitative structure–activity relationship, Stereochemistry, In silico, negative inotropic activity, ATP Binding Cassette Transporter, Fingerprints for Ligands and Proteins (FLAP), L-Type Calcium Channels (LTCC), Article, lcsh:QD241-441, lcsh:Organic chemistry, Homology modeling, Physical and Theoretical Chemistry, multidrug resistance (MDR1), 3D-QSAR, Structural Homology, Virtual screening, Calcium channel, Protein, Organic Chemistry, Combinatorial chemistry, Docking (molecular), pharmacophore modeling

    وصف الملف: application/pdf; STAMPA

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61554762b7203fa9fbc751ecaa3e5b93Test
    https://hdl.handle.net/11576/2696050Test


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