-
1دورية أكاديمية
مصطلحات موضوعية: Advancements in Lung Cancer Research, Pulmonary and Respiratory Medicine, Medicine, Health Sciences, Natural Products as Sources of New Drugs, Pharmacology, DNA Topoisomerases Structure, Function, and Inhibition, Molecular Biology, Biochemistry, Genetics and Molecular Biology, Life Sciences, EGFR Mutations, T790M, Epidermal growth factor receptor, EGFR inhibitors, Cancer research, Breast cancer, Drug resistance, Apoptosis, Drug, Cancer, Lapatinib, Cancer cell, Cell growth, Gefitinib, Kinase, Chemistry, Biology, Internal medicine, Biochemistry, Trastuzumab
-
2دورية أكاديمية
المؤلفون: Yangcheng Ai (14394757), Zichao Yang (2002318), Zilong Yang (14394760), Shanhe Wan (3875341), Chunhui Huang (1505923), Chuan Huang (755258), Mingxia Li (547512), Zhonghuang Li (4382497), Jiajie Zhang (43131), Tingting Zhang (264633)
مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, study could enhance, withdrawing substituents introduced, electrophilic group cyanoacrylamide, different electrophilic substituents, results might help, molecular dynamics simulations, reversible noncovalent inhibitors, α sub, withdrawing groups play, kinase assay experiment, reversible covalent inhibitors, withdrawing groups, electrophilic groups, covalent inhibitors, results suggested, molecular docking, egfr inhibitors, warheads reacting, structural information, steric complementarity, specific interactions, reverse β, olefin bond
-
3دورية أكاديمية
المؤلفون: Hualin Zhang (11948553), Ruliang Xie (11948556), Hawaa AI-furas (11948559), Yupeng Li (507508), Qingxia Wu (11948562), Jian Li (41607), Fang Xu (138747), Tianfeng Xu (1884211)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, develop therapeutic agents, acquired mutational resistance, one representative compound, molecule inhibitors targeting, generation egfr inhibitors, c797s mutation predominates, 6h b, 50 sub, egfr c797s mutants, egfr c797s mutation, c797s triple mutant, c797s sup, f3 cells expressing, c797s mutation, targeting chimeras, lead compound
-
4دورية أكاديمية
المؤلفون: Mostafa M. Elbadawi (11856706), Wagdy M. Eldehna (4260952), Amer Ali Abd El-Hafeez (11539579), Warda R. Somaa (11856709), Amgad Albohy (629887), Sara T. Al-Rashood (6305897), Keli K. Agama (11856712), Eslam B. Elkaeed (9952518), Pradipta Ghosh (52052), Yves Pommier (11158), Manabu Abe (362853)
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Quinoline, anticancer, EGFR inhibitors, FAK inhibitors, molecular dynamics
-
5
المؤلفون: Wenyi Wei, Songqing Fan, Guoqing Qian, Karin A. Vallega, Qiming Wang, Yunfu Deng, Zhen Chen, Suresh S. Ramalingam, Jianping Guo, Taofeek K. Owonikoko, Changjiang Hu, Shi-Yong Sun
المصدر: Mol Cancer Res
مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Ubiquitin-Protein Ligases, Mice, Nude, Apoptosis, B7-H1 Antigen, Article, Cell Line, Glycogen Synthase Kinase 3, Mice, Ubiquitin, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, PD-L1, Animals, Humans, Osimertinib, Epidermal growth factor receptor, Protein Kinase Inhibitors, Molecular Biology, EGFR inhibitors, Acrylamides, Gene knockdown, Aniline Compounds, biology, Chemistry, Ubiquitin ligase, ErbB Receptors, Gene Expression Regulation, Neoplastic, HEK293 Cells, Oncology, Mutation, Cancer cell, biology.protein, Cancer research, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49618826ca7fd0d978235270c398bde2Test
https://doi.org/10.1158/1541-7786.mcr-21-0147Test -
6
المؤلفون: Wenying Shu, Janney Z. Wang, Svetlana Cherepanoff, Michael Murray, Michele C. Madigan, Fanfan Zhou, R Max Conway, Hong Zhu, Vivian Lin, Ke Wang, Elsa Toumi
المصدر: The FEBS Journal. 288:6226-6249
مصطلحات موضوعية: Uveal Neoplasms, 0301 basic medicine, medicine.medical_treatment, Malignancy, Biochemistry, Metastasis, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Melanoma, Molecular Biology, EGFR inhibitors, GNA11, business.industry, Cell Biology, Immunotherapy, Proto-Oncogene Proteins c-met, medicine.disease, Histone Deacetylase Inhibitors, 030104 developmental biology, 030220 oncology & carcinogenesis, Cutaneous melanoma, Cancer research, business, GNAQ
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc7fa06c974537af2b43a0d989e4448Test
https://doi.org/10.1111/febs.15869Test -
7
المؤلفون: Martin J. Edelman, Oleg I. Kit, Elena M. Frantsiyants, Rohan Brebion, Eleanor Avril, Kathy Q. Cai, Bulat Faezov, Iuliia Topchu, Rushaniya Fazliyeva, Ilya G. Serebriiskii, Emmanuelle Nicolas, Leonid V. Kharin, Petr Makhov, Yanis Boumber, Erica A. Golemis, Alexander E. Kudinov, Hossein Borghaei, Igor Bychkov, Alexander Y. Deneka, Anna S. Nikonova, Nikolay S. Karnaukhov, Essel Dulaimi, Mark Voloshin
المصدر: Oncogenesis, Vol 10, Iss 3, Pp 1-14 (2021)
Oncogenesisمصطلحات موضوعية: 0301 basic medicine, Cancer Research, Afatinib, non-small cell lung cancer (NSCLC), lcsh:RC254-282, Article, 03 medical and health sciences, 0302 clinical medicine, medicine, Osimertinib, Epidermal growth factor receptor, Molecular Biology, EGFR inhibitors, biology, Cell growth, Chemistry, Reverse phase protein lysate microarray, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, respiratory tract diseases, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Erlotinib, Non-small-cell lung cancer, medicine.drug, Post-translational modifications
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3f337bb99129d6a76a8fd9939b769aTest
https://doaj.org/article/2ede848ef5274440b27190aa152d7cbeTest -
8
المؤلفون: Yongcui Wang, Shilong Chen, Rui Yuan
المصدر: Biomolecules, Vol 11, Iss 1042, p 1042 (2021)
Biomolecules
Volume 11
Issue 7مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, EGFR inhibitors effectiveness related methylation sites, group lasso, Biology, Biochemistry, Microbiology, Article, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Promoter Regions, Genetic, Enhancer, Protein Kinase Inhibitors, Molecular Biology, Gene, EGFR inhibitors, DNA methylation, Computational Biology, Cancer, Promoter, Methylation, medicine.disease, QR1-502, ErbB Receptors, Gene Expression Regulation, Neoplastic, lung cancer, Enhancer Elements, Genetic, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Pharmacogenomics, CTRP and CCLE, Cancer research
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba5a575ab56b45e4403f8bb2231a231Test
https://www.mdpi.com/2218-273X/11/7/1042Test -
9
المؤلفون: Jordan P. Reynolds, Charis Eng, Ying Ni, Roshan Padmanabhan, Sara Akhavanfard, Lamis Yehia
المصدر: Human Molecular Genetics. 29:3679-3690
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Adolescent, Genotype, Population, Biology, Germline, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Exome Sequencing, Adrenocortical Carcinoma, Genetics, medicine, Humans, Adrenocortical carcinoma, Genetic Predisposition to Disease, MEN1, Precision Medicine, education, Molecular Biology, Germ-Line Mutation, Genetics (clinical), Exome sequencing, EGFR inhibitors, education.field_of_study, Sunitinib, Cancer, General Medicine, Middle Aged, medicine.disease, ErbB Receptors, Gene Expression Regulation, Neoplastic, Phenotype, 030104 developmental biology, 030220 oncology & carcinogenesis, ras Proteins, Cancer research, Female, Tumor Suppressor Protein p53, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318148476122dbd39ec96fee49a5558aTest
https://doi.org/10.1093/hmg/ddaa268Test -
10
المؤلفون: Iqrar Ahmad, Arabinda Ghosh, Sanjay J. Surana, Harun M. Patel, Matin Shaikh
المصدر: Journal of Biomolecular Structure and Dynamics. 40:3046-3059
مصطلحات موضوعية: Lung Neoplasms, non-small cell lung cancer (NSCLC), Mitogen-Activated Protein Kinase 14, Structural Biology, Carcinoma, Non-Small-Cell Lung, Fourth generation, medicine, Humans, Point Mutation, Osimertinib, Epidermal growth factor receptor, Protein Kinase Inhibitors, Molecular Biology, EGFR inhibitors, Acrylamides, Aniline Compounds, integumentary system, biology, Point mutation, General Medicine, medicine.disease, respiratory tract diseases, ErbB Receptors, Drug Resistance, Neoplasm, Egfr mutation, Mitogen-activated protein kinase, Mutation, biology.protein, Cancer research
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f31142039475ffc50a19319c4875a2Test
https://doi.org/10.1080/07391102.2020.1844801Test