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51
المؤلفون: Shanhe Wan, Zhonghuang Li, Qian Guo, Jiajie Zhang, Qinlan Li, Xiaoyun Wu
مصطلحات موضوعية: Lung Neoplasms, Afatinib, Allosteric regulation, Molecular Dynamics Simulation, T790M, Gefitinib, Adenosine Triphosphate, Structural Biology, Carcinoma, Non-Small-Cell Lung, medicine, Humans, Osimertinib, Epidermal growth factor receptor, Molecular Biology, Protein Kinase Inhibitors, EGFR inhibitors, biology, Chemistry, General Medicine, ErbB Receptors, Drug Resistance, Neoplasm, Mutation, Cancer research, biology.protein, Erlotinib, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d212db7fb9eb00a15b1dcace7e9726c9Test
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المؤلفون: Daniel Fábio Kawano, Martina Godel, Przemysław Biegański, Chiara Riganti, Konrad Kowalski, Joanna Kopecka
مصطلحات موضوعية: Lung Neoplasms, Cell Survival, Antineoplastic Agents, Biochemistry, Erlotinib Hydrochloride, Structure-Activity Relationship, Docking (dog), Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Discovery, medicine, Humans, heterocyclic compounds, Lung cancer, neoplasms, Molecular Biology, Protein Kinase Inhibitors, EGFR inhibitors, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Click chemistry, Organic Chemistry, Triazoles, medicine.disease, In vitro, respiratory tract diseases, ErbB Receptors, Mechanism of action, Erlotinib, Apoptosis, Drug Resistance, Neoplasm, Drug resistance, Cancer cell, Ferrocene, Cancer research, medicine.symptom, Drug Screening Assays, Antitumor, Iron Compounds, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7753eeefded4ef2b8210798b85c044Test
http://hdl.handle.net/2318/1824284Test -
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المؤلفون: adel A. Elgendy, Aliaa M. Kamal, Marian W. Aziz, Khaled Mohamed
المصدر: Bioorganicmedicinal chemistry letters. 41
مصطلحات موضوعية: Quantitative structure–activity relationship, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, Pharmacology, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Structure-Activity Relationship, Gefitinib, Drug Discovery, medicine, Humans, Cytotoxicity, Molecular Biology, Quinazolinone, Protein Kinase Inhibitors, EGFR inhibitors, Cell Proliferation, Quinazolinones, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, 0104 chemical sciences, ErbB Receptors, 010404 medicinal & biomolecular chemistry, chemistry, A549 Cells, Drug Design, MCF-7 Cells, Molecular Medicine, Pharmacophore, Drug Screening Assays, Antitumor, Acetamide, Discovery Studio, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b8bf4bfd29bfe0c3f662dcc6938a24Test
https://pubmed.ncbi.nlm.nih.gov/33771586Test -
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المصدر: Bioorganicmedicinal chemistry. 36
مصطلحات موضوعية: Indoles, Pyrimidine, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, 01 natural sciences, Biochemistry, chemistry.chemical_compound, T790M, Structure-Activity Relationship, In vivo, Drug Discovery, Tumor Cells, Cultured, Humans, Osimertinib, Molecular Biology, Protein Kinase Inhibitors, EGFR inhibitors, Cell Proliferation, Indole test, Acrylamides, Aniline Compounds, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, In vitro, 0104 chemical sciences, ErbB Receptors, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Pyrimidines, chemistry, Mutation, Molecular Medicine, Drug Screening Assays, Antitumor, Lead compound
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27906a9eee1cc5c503471541fcf70f30Test
https://pubmed.ncbi.nlm.nih.gov/33667898Test -
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المصدر: Sci Signal
مصطلحات موضوعية: Triple Negative Breast Neoplasms, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Cell Line, Tumor, medicine, Humans, MCL1, Epidermal growth factor receptor, Molecular Biology, Triple-negative breast cancer, Histone Acetyltransferases, 030304 developmental biology, EGFR inhibitors, 0303 health sciences, biology, business.industry, Cancer, Cell Biology, Oncogene Addiction, medicine.disease, ErbB Receptors, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Myeloid Cell Leukemia Sequence 1 Protein, Female, Erlotinib, business, Signal Transduction, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e601a909d306f0dd07774f8f5961458Test
https://doi.org/10.1126/scisignal.abb9820Test -
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المؤلفون: Noah K Schomburg, Edward C. Stites, Kent L. Rossman, Thomas McFall
المصدر: Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-7 (2020)مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, endocrine system diseases, Colorectal cancer, medicine.medical_treatment, lcsh:Medicine, medicine.disease_cause, Biochemistry, Targeted therapy, 0302 clinical medicine, Fluorescence Resonance Energy Transfer, EGFR inhibitors, Cancer, 0303 health sciences, Neurofibromin 1, Cetuximab, lcsh:Cytology, ErbB Receptors, 030220 oncology & carcinogenesis, KRAS, Colorectal Neoplasms, medicine.drug, Protein Binding, EGFR, Short Report, Biology, Biophysical Phenomena, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, medicine, Humans, HRAS, lcsh:QH573-671, Molecular Biology, neoplasms, GTPase, Protein Kinase Inhibitors, 030304 developmental biology, lcsh:R, Cell Biology, medicine.disease, HCT116 Cells, digestive system diseases, respiratory tract diseases, HEK293 Cells, Mutation, Cancer research, Mutant Proteins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e430e3a0d96b96a00a5d8206bceee4Test
http://europepmc.org/articles/PMC7643456Test -
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المؤلفون: Han Li, Yan-Fang Wang, Zhi-Wan Wang, Su-Zhen Zhou, Ning Li, Ming-hang Wang
المصدر: Cell Cycle
مصطلحات موضوعية: 0301 basic medicine, Male, STAT3 Transcription Factor, Lung Neoplasms, Carcinogenesis, Mice, Nude, Apoptosis, Biology, medicine.disease_cause, 03 medical and health sciences, Mice, 0302 clinical medicine, Annexin, Cell Line, Tumor, medicine, Animals, Humans, Osimertinib, STAT3, Molecular Biology, Protein Kinase Inhibitors, EGFR inhibitors, Cell Proliferation, Gene knockdown, Acrylamides, Mice, Inbred BALB C, Aniline Compounds, Cell growth, Cell Biology, Middle Aged, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030104 developmental biology, A549 Cells, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, RNA, Long Noncoding, Developmental Biology, Signal Transduction, Research Paper
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8675c5d6fd312689d60f807647566f9fTest
https://pubmed.ncbi.nlm.nih.gov/33064977Test -
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المؤلفون: Daryono H. Tjahjono, Frangky Sangande, Elin Julianti
المصدر: International Journal of Molecular Sciences, Vol 21, Iss 7779, p 7779 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20مصطلحات موضوعية: 0301 basic medicine, dual inhibitor, Databases, Pharmaceutical, Drug Evaluation, Preclinical, Ligands, Tyrosine-kinase inhibitor, lcsh:Chemistry, 0302 clinical medicine, Epidermal growth factor receptor, lcsh:QH301-705.5, Spectroscopy, EGFR inhibitors, biology, Chemistry, General Medicine, Computer Science Applications, ErbB Receptors, Molecular Docking Simulation, Axitinib, VEGFR2, 030220 oncology & carcinogenesis, cardiovascular system, Erlotinib, Pharmacophore, Tyrosine kinase, medicine.drug, ligand-based pharmacophore, medicine.drug_class, EGFR, Antineoplastic Agents, Molecular Dynamics Simulation, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, medicine, Physical and Theoretical Chemistry, Protein Kinase Inhibitors, Molecular Biology, Organic Chemistry, Hydrogen Bonding, molecular docking, Vascular Endothelial Growth Factor Receptor-2, molecular dynamics, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Docking (molecular), Cancer research, biology.protein
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9077a9f9d5cc7f842b1c0811d9942198Test
https://www.mdpi.com/1422-0067/21/20/7779Test -
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المؤلفون: Kranti Konganti, Erica S. Rinella, Ming Yu, Kathryn R Anderson, Jorge Jaimes-Alvarado, David W. Threadgill, Rachel M Lynch, Amie Perry, Carolina Mantilla-Rojas, Evann J Bourgeois, Estefania Barba
المصدر: Oncogene
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Colorectal cancer, medicine.disease_cause, Article, Interleukin 10 receptor, alpha subunit, 03 medical and health sciences, Mice, 0302 clinical medicine, Genetics, medicine, Animals, Epidermal growth factor receptor, Molecular Biology, neoplasms, EGFR inhibitors, Cell Proliferation, biology, Cell growth, medicine.disease, digestive system diseases, Interleukin-10, ErbB Receptors, Interleukin 10, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, KRAS, Colorectal Neoplasms, Proto-oncogene tyrosine-protein kinase Src, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f764c445cd0893d1adacfbd68e3328Test
https://pubmed.ncbi.nlm.nih.gov/33767440Test -
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المؤلفون: Suresh Palanivel (10341476), Olli Yli-Harja (21562), Meenakshisundaram Kandhavelu (5698217)
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, EGFR inhibitors, Indolines, computational analysis, molecular targets, ADME/Tox, QM/MM, protein-ligand complex