المؤلفون: Roland Seifert, Katharina Wenzel-Seifert

المصدر: Immunobiology. 181:298-316

مصطلحات موضوعية: Calcium/metabolism, Cytochalasin B, G protein, Glucuronidase/secretion, Immunology, 610 Medizin, Cytochalasin B/pharmacology, Pertussis toxin, Exocytosis, chemistry.chemical_compound, 615 Pharmazie, Superoxides, Phorbol Esters, Tumor Cells, Cultured, medicine, Exocytosis/physiology, Humans, Immunology and Allergy, Nucleotide, Leukemia/physiopathology, Glucuronidase, Nucleotides/pharmacology, chemistry.chemical_classification, ddc:610, Leukemia, Tumor Cells, Cultured/physiology, Phospholipase C, Nucleotides, Chemistry, Bucladesine/pharmacology, Cell Differentiation, Hematology, N-Formylmethionine leucyl-phenylalanine, Molecular biology, Adenosine, ddc:615, Phorbol Esters/pharmacology, N-Formylmethionine Leucyl-Phenylalanine, Bucladesine, Cell Differentiation/drug effects, Calcium, Superoxides/metabolism, N-Formylmethionine Leucyl-Phenylalanine/pharmacology, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dd4b8a3cb3f415be960de2c442c9eaTest
https://doi.org/10.1016/s0171-2985Test(11)80499-7

المؤلفون: Catherine Guerreiro, Bruno Canard, Hélène Dutartre, Magali Sophys, Michel Véron, Laurence A. Mulard, Benoit Schneider, Yuxing Chen, Dominique Deville-Bonne, Sarah Gallois-Montbrun, Solange Moréra, Joël Janin

المساهمون: Régulation Enzymatique des Activités Cellulaires, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'enzymologie et biochimie structurales (LEBS), Centre National de la Recherche Scientifique (CNRS), Architecture et fonction des Macromolécules Biologiques - UMR 6098 (AFMB), Université de Provence - Aix-Marseille 1-Centre National de la Recherche Scientifique (CNRS), Chimie Organique, Enzymologie Moléculaire et Fonctionnelle, Université Pierre et Marie Curie - Paris 6 (UPMC), Architecture et fonction des macromolécules biologiques (AFMB), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA), This work was supported by Ministere de l'Education Nationale, Ministere de la Recherche et de la Technologie (Program Microbiologie, Maladies Infectieuses et Parasitaires), by Association pour la Recherche contre le Cancer, and by Association Nationale de Recherche contre le Sida (ANRS) and by Sidaction-Ensemble contre le SIDA., We gratefully acknowledge C. Meier (Universität Hamburg, Hamburg, Germany) for kindly providing ribavirin. We thank S. Sarfati (Unité de Chimie Organique, Institut Pasteur) for initial input in the work and Céline Boulard for excellent technical assistance. We are deeply indebted to Sonia Longhi for mutagenesis experiments to reduce the number of rare codons in the HCV polymerase cDNA., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of Science and Technology of China [Hefei] (USTC), Oncogenèse rétrovirale – Retroviral Oncogenesis, Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Enzymologie et Biochimie Structurales (LEBS), Chimie des biomolécules, Institut National de la Santé et de la Recherche Médicale (INSERM), Chimie des Biomolécules

المصدر: Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2003, 63 (3), pp.538-546. ⟨10.1124/mol.63.3.538⟩
Molecular Pharmacology, 2003, 63 (3), pp.538-546. ⟨10.1124/mol.63.3.538⟩

مصطلحات موضوعية: Protein Conformation, MESH: Catalytic Domain, Crystallography, X-Ray, chemistry.chemical_compound, MESH: Protein Conformation, Catalytic Domain, Nucleotide, MESH: Nucleotides/pharmacology, Polymerase, chemistry.chemical_classification, 0303 health sciences, Kinase, Nucleotides, virus diseases, DNA-Directed RNA Polymerases, 3. Good health, Biochemistry, MESH: Ribavirin/analogs & derivatives, MESH: Ribavirin/chemistry, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Molecular Medicine, medicine.drug, MESH: Nucleoside-Diphosphate Kinase/chemistry, MESH: Binding, Competitive, Biology, Binding, Competitive, 03 medical and health sciences, Ribose, Ribavirin, MESH: Nucleic Acid Synthesis Inhibitors, medicine, Humans, 030304 developmental biology, Nucleic Acid Synthesis Inhibitors, Pharmacology, MESH: Humans, Nucleoside analogue, 030306 microbiology, RNA, MESH: Crystallography, X-Ray, Molecular biology, Reverse transcriptase, MESH: Nucleotides/chemistry, Enzyme, chemistry, Nucleoside-Diphosphate Kinase, biology.protein, MESH: Ribavirin/metabolism, MESH: DNA-Directed RNA Polymerases/antagonists & inhibitors, MESH: Nucleoside-Diphosphate Kinase/metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9073de076804ab9a48eefbda4b1575ffTest
https://hal.archives-ouvertes.fr/hal-02459258Test

المؤلفون: Roland Seifert, Günter Schultz, Walter Rosenthal

المصدر: FEBS Letters. 205:161-165

مصطلحات موضوعية: GTP', Neutrophils, 610 Medizin, Biophysics, Biochemistry, Calcium in biology, Guanine nucleotide-binding protein, chemistry.chemical_compound, 615 Pharmazie, Superoxides, Structural Biology, Cell Membrane/enzymology, Genetics, Humans, Guanosine Triphosphate/pharmacology, NADH, NADPH Oxidoreductases, Molecular Biology, Protein kinase C, chemistry.chemical_classification, ddc:610, NADPH oxidase, biology, Superoxide, Cell Membrane, Neutrophil, Superoxides/blood, NADPH Oxidases, Cell Biology, Thionucleotides, Guanine Nucleotides/pharmacology, Guanine Nucleotides, ddc:615, Thionucleotides/pharmacology, Enzyme Activation, Cytosol, Enzyme, Arachidonic acid, chemistry, Guanosine 5'-O-(3-Thiotriphosphate), Neutrophils/enzymology, biology.protein, Enzyme Activation/drug effects, NADH, NADPH Oxidoreductases/blood, Guanosine Triphosphate

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e5cf57352b9e02dc331c142aa115d6Test
https://doi.org/10.1016/0014-5793Test(86)80886-9

المؤلفون: Roland Seifert, Günter Schultz, Rahel Burde

مصطلحات موضوعية: Purine, P2Y receptor, NADH, NADPH Oxidoreductases/metabolism, Uracil Nucleotides/pharmacology, Neutrophils, Uracil Nucleotides, G protein, 610 Medizin, Adenylate kinase, Uridine Triphosphate, NADPH Oxidase, Pertussis toxin, GTP-Binding Proteins/physiology, Biochemistry, chemistry.chemical_compound, Adenosine Triphosphate, 615 Pharmazie, GTP-Binding Proteins, Superoxides, Uridine Triphosphate/pharmacology, Tumor Cells, Cultured, Humans, NADH, NADPH Oxidoreductases, Nucleotide, heterocyclic compounds, Molecular Biology, chemistry.chemical_classification, ddc:610, NADPH oxidase, biology, Chemistry, Superoxide, NADPH Oxidases, Cell Biology, Tumor Cells, Cultured/enzymology, Molecular biology, ddc:615, Enzyme Activation, N-Formylmethionine Leucyl-Phenylalanine, Bucladesine, biology.protein, Neutrophils/enzymology, Enzyme Activation/drug effects, Superoxides/metabolism, Adenosine Triphosphate/pharmacology, N-Formylmethionine Leucyl-Phenylalanine/pharmacology, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b06c6f322ba7e5e77db60f904b0a0ccTest

المؤلفون: Michal Svoboda, Monique Lambert, Jean Christophe

المصدر: Biochimica et biophysica acta, 675 (1

مصطلحات موضوعية: Cholera Toxin, GTP', Stereochemistry, Biophysics, medicine.disease_cause, Biochemistry, Cyclase, Sincalide, Reaction rate constant, medicine, Animals, Cholera Toxin -- pharmacology, Molecular Biology, Pancreas, Cholecystokinin, Guanine Nucleotides -- pharmacology, Chemistry, Pancreas -- enzymology, Cholera toxin, Cell Membrane, Enzyme Activation -- drug effects, Sciences bio-médicales et agricoles, Dibutyryl Cyclic GMP, Adenylyl Cyclases -- metabolism, Guanine Nucleotides, Peptide Fragments, Rats, Enzyme Activation, Kinetics, Steady state (chemistry), Cyclase activity, Cell Membrane -- enzymology, Peptide Fragments -- pharmacology, Cholecystokinin -- analogs & derivatives -- pharmacology, Adenylyl Cyclases

وصف الملف: 2 full-text file(s): application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c5e40dd75a3409b343aac1c59d1698Test
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/87089Test

المؤلفون: Jean Claude Camus, Pierre Chatelain, Patrick Robberecht, Alain Verloes, Roland Pochet, Jean Christophe, Philippe De Neef

المصدر: FEBS letters, 132 (1
Scopus-Elsevier

مصطلحات موضوعية: Male, medicine.medical_specialty, Secretin pharmacology, Vasoactive intestinal peptide, Enzymologie, Biophysics, Adenylate Cyclase metabolism, Adenylate kinase, Guanine Nucleotides pharmacology, Biochemistry, Cyclase, Glucagon, Secretin, Hypothyroidism, Structural Biology, Internal medicine, Myocardium enzymology, Genetics, medicine, Animals, Molecular Biology, Hypothyroidism enzymology, Triiodothyronine, Chemistry, Sodium Fluoride pharmacology, Myocardium, Isoproterenol, Rats, Inbred Strains, Cell Biology, Isoproterenol pharmacology, Guanine Nucleotides, Rats, Enzyme Activation, Membrane, Endocrinology, Glucagon pharmacology, hypothyroid, secretin, adenylate cyclase, Sodium Fluoride, Propylthiouracil, Enzyme Activation drug effects, Adenylyl Cyclases, medicine.drug

وصف الملف: 2 full-text file(s): application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86451d330f353d448470992a1f993e59Test
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/44126Test

المؤلفون: Günter Schultz, Roland Seifert

مصطلحات موضوعية: Neutrophils, 610 Medizin, Protein Kinase C/metabolism, NADPH Oxidase, Sodium Dodecyl Sulfate/pharmacology, Biochemistry, chemistry.chemical_compound, Lipoxygenase, Cytosol, 615 Pharmazie, Cell Membrane/enzymology, Cytosol/enzymology, Humans, NADH, NADPH Oxidoreductases, Guanosine Triphosphate/pharmacology, Protein kinase A, Protein Kinase C, Protein kinase C, chemistry.chemical_classification, Fatty Acids, Unsaturated/pharmacology, ddc:610, NADPH oxidase, biology, Superoxide, Cell Membrane, Fatty Acids, NADPH Oxidases, Sodium Dodecyl Sulfate, Fatty acid, Drug Synergism, Thionucleotides, Molecular biology, Guanine Nucleotides/pharmacology, Guanine Nucleotides, Fatty Acids/pharmacology, ddc:615, Thionucleotides/pharmacology, Enzyme Activation, chemistry, Guanosine 5'-O-(3-Thiotriphosphate), Fatty Acids, Unsaturated, biology.protein, Neutrophils/enzymology, Arachidonic acid, Enzyme Activation/drug effects, Guanosine Triphosphate, NADH, NADPH Oxidoreductases/blood

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575b9d6d4f08ddc0766df2724b97aa7eTest
https://epub.uni-regensburg.de/23273Test/