المؤلفون: Juri Rappsilber, Pablo Alcón, Lori A. Passmore, Shabih Shakeel, Zhuo A. Chen, Ketan J. Patel

المصدر: Alcón, P, Shakeel, S, Chen, Z A, Rappsilber, J, Patel, K J & Passmore, L A 2020, ' FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair ', Nature Structural and Molecular Biology, vol. 27, no. 3, pp. 240-248 . https://doi.org/10.1038/s41594-020-0380-1Test
Nature structural & molecular biology

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, DNA damage, DNA repair, DNA-binding protein, Article, law.invention, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Ubiquitin, Structural Biology, law, hemic and lymphatic diseases, FANCD2, Monoubiquitination, Molecular Biology, 030304 developmental biology, 0303 health sciences, biology, nutritional and metabolic diseases, Cell biology, chemistry, Recombinant DNA, biology.protein, 030217 neurology & neurosurgery, DNA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dee59bf22e62e4f4da816000c77deeTest
https://www.pure.ed.ac.uk/ws/files/157669496/PMID32066963_AAM_Rappsilber.pdfTest

المؤلفون: Etsuro Ito, Seiji Kojima, Kenichi Yoshida, Rui Yu, Camille Nadler, Paul S. Monks, Asuka Hira, Nicola K. Wilson, Motohiro Kato, Ashley N. Kamimae-Lanning, Satoru Miyano, Hiromasa Yabe, Tomoo Osumi, Minako Mori, Miharu Yabe, Michael R. G. Hodskinson, Minoru Takata, Hideki Muramatsu, Lucas B. Pontel, Seishi Ogawa, Toshinori Moriguchi, Christopher L. Millington, Yusuke Okamoto, Masayuki Kobayashi, Yuichi Shiraishi, Meng Wang, Ketan J. Patel, Frederic Langevin, Berthold Göttgens, Yusuke Okuno, Sam Watcham, Felix A. Dingler, Rebecca Cordell, Keitaro Matsuo, Nina Oberbeck, Anfeng Mu

المساهمون: Wilson, Nicola [0000-0003-0865-7333], Gottgens, Berthold [0000-0001-6302-5705], Apollo - University of Cambridge Repository

المصدر: Molecular Cell
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: Male, DNA Repair, Somatic cell, medicine.disease_cause, Substrate Specificity, purl.org/becyt/ford/1 [https], DNA Adducts, Mice, 0302 clinical medicine, Child, IMMUNODEFICIENCY, 0303 health sciences, Mutation, Leukemia, Aldehyde Dehydrogenase, Mitochondrial, CANCER, Cell biology, Child, Preschool, Female, Stem cell, mutagenesis, Adolescent, DNA repair, DNA damage, AGEING, Biology, HEMATOPOIESIS, DNA DAMAGE, Article, 03 medical and health sciences, medicine, Animals, Humans, cancer, FORMALDEHYDE, HEMATOPOIETIC STEM CELLS, purl.org/becyt/ford/1.6 [https], Molecular Biology, 030304 developmental biology, ALDH2, Aldehydes, MUTAGENESIS, Mutagenesis, Alcohol Dehydrogenase, Infant, ONCOMETABOLITE, Cell Biology, medicine.disease, oncometabolite, hematopoiesis, hematopoietic stem cells, BONE MARROW FAILURE, ageing, formaldehyde, bone marrow failure, immunodeficiency, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d65d6f96b03ddf58df2484332f40f7Test
http://hdl.handle.net/2433/255881Test

المؤلفون: Rui Yu, Verena Broecker, Guillermo Burgos-Barragan, James A. Swenberg, Mark J. Arends, Gayathri Chandrasekaran, Ketan J. Patel, Gerry P. Crossan, Lucas B. Pontel, Wei Wei, Limin Liu, Iván V. Rosado, Juan I. Garaycoechea

المساهمون: Universidad de Sevilla. Departamento de Genética, Medical Research Council. UK, Instituto de Salud Carlos III. España, Ministerio de Economía y Competitividad (MINECO). España, National Institute of Environmental Health Sciences (NIEHS). U.S., Texas Commission for Environmental Quality. U.S., Wellcome Trust. UK

المصدر: idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Molecular Cell
Pontel, L B, Rosado, I V, Burgos-Barragan, G, Garaycoechea, J I, Yu, R, Arends, M J, Chandrasekaran, G, Broecker, V, Wei, W, Liu, L, Swenberg, J A, Crossan, G P & Patel, K J 2015, ' Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen ', Molecular Cell, vol. 60, no. 1, pp. 177-188 . https://doi.org/10.1016Test/j.molcel.2015.08.020

مصطلحات موضوعية: DNA damage, Endogeny, Kidney, Article, DNA Adducts, Gene Knockout Techniques, Mice, Formaldehyde, medicine, Animals, Molecular Biology, Carcinogen, Cells, Cultured, Alcohol dehydrogenase, biology, Fanconi Anemia Complementation Group D2 Protein, Alcohol Dehydrogenase, Kidney metabolism, Hematopoietic stem cell, Cell Biology, Hematopoietic Stem Cells, Molecular biology, 3. Good health, Cell biology, Haematopoiesis, medicine.anatomical_structure, Liver, biology.protein, Carcinogens, Stem cell, Mutagens

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8f1fa5e33bd087a5587511933f8814Test

المؤلفون: Ketan J. Patel, Lori A. Passmore, Juan I. Garaycoechea, Eeson Rajendra

المصدر: Nucleic Acids Research

مصطلحات موضوعية: Genome instability, DNA repair, Ataxia Telangiectasia Mutated Proteins, Biology, Genome Integrity, Repair and Replication, Cell Line, chemistry.chemical_compound, Fanconi anemia, Chromosome instability, Genetics, RUVBL2, medicine, Animals, Humans, Gene, Adenosine Triphosphatases, Mice, Knockout, DNA Helicases, Anemia, Aplastic, DNA Repair Pathway, medicine.disease, Hematopoietic Stem Cells, Molecular biology, Fanconi Anemia Complementation Group Proteins, Cross-Linking Reagents, chemistry, ATPases Associated with Diverse Cellular Activities, Carrier Proteins, Chickens, DNA, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56df4227f8207ef12c9891eba9152625Test
http://europepmc.org/articles/PMC4267650Test

المؤلفون: Juan I. Garaycoechea, Jan Silhan, Orlando D. Schärer, Shivam Mukherjee, Michael R. G. Hodskinson, Gerry P. Crossan, Ketan J. Patel, Christopher M. Johnson

المصدر: Molecular Cell

مصطلحات موضوعية: Genome instability, DNA Repair, DNA damage, DNA repair, Bone Marrow Cells, Mice, Transgenic, macromolecular substances, Biology, Article, Recombinases, DNA Adducts, Mice, chemistry.chemical_compound, Neoplasms, DNA Crosslinking, Animals, Replication protein A, Molecular Biology, Nuclease, Base Sequence, Tumor Suppressor Proteins, technology, industry, and agriculture, Cell Biology, Endonucleases, Hematopoietic Stem Cells, Molecular biology, DNA-Binding Proteins, Mice, Inbred C57BL, chemistry, biology.protein, Nucleic Acid Conformation, DNA, DNA Damage, Nucleotide excision repair

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d241584e6440b138596dda1fde877445Test

المؤلفون: Meng Wang, Gillian L. Dornan, Vibe H. Oestergaard, Ketan J. Patel, Eeson Rajendra, Lori A. Passmore, Frederic Langevin

المصدر: Molecular Cell
Rajendra, E, Østergaard, V H, Langevin, F, Wang, M, Dornan, G L, Patel, K J & Passmore, L A 2014, ' The genetic and biochemical basis of FANCD2 Monoubiquitination ', Molecular Cell, vol. 54, no. 5, pp. 858-869 . https://doi.org/10.1016Test/j.molcel.2014.05.001

مصطلحات موضوعية: Protein subunit, Fanconi Anemia Complementation Group L Protein, macromolecular substances, Article, Cell Line, Avian Proteins, Ubiquitin, hemic and lymphatic diseases, FANCD2, Monoubiquitination, Animals, Humans, FANCL, Molecular Biology, biology, Fanconi Anemia Complementation Group D2 Protein, Ubiquitination, Cell Biology, DNA Repair Pathway, Fanconi Anemia Complementation Group Proteins, 3. Good health, Ubiquitin ligase, FANCB, Fanconi Anemia, Biochemistry, biology.protein, Ubiquitin-Specific Proteases, Chickens

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc897ac6045bb202e976d341868da36aTest
http://europepmc.org/articles/PMC4051986Test

المؤلفون: Ketan J. Patel, Arno F. Alpi, M. Madan Babu, Paul E. Pace

المصدر: Molecular Cell. 32:767-777

مصطلحات موضوعية: Molecular Sequence Data, Fanconi Anemia Complementation Group L Protein, Cell Line, Substrate Specificity, law.invention, chemistry.chemical_compound, Ubiquitin, Fanconi anemia, law, hemic and lymphatic diseases, FANCD2, medicine, Animals, Humans, Monoubiquitination, FANCL, Amino Acid Sequence, Molecular Biology, Conserved Sequence, biology, Fanconi Anemia Complementation Group D2 Protein, Ubiquitination, Cell Biology, medicine.disease, Fanconi Anemia Complementation Group Proteins, Protein Structure, Tertiary, Chromatin, Biochemistry, chemistry, Ubiquitin-Conjugating Enzymes, biology.protein, Suppressor, Chickens, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894f602f8bda7dcba2adf701913100adTest
https://doi.org/10.1016Test/j.molcel.2008.12.003

المؤلفون: Arno F. Alpi, Georgina Mosedale, Frederic Langevin, Yuichi J. Machida, Anindya Dutta, Ketan J. Patel

المصدر: Molecular and Cellular Biology. 27:8421-8430

مصطلحات موضوعية: Multiprotein complex, DNA damage, Fanconi Anemia Complementation Group L Protein, Ubiquitin-conjugating enzyme, Cell Line, Ubiquitin, Catalytic Domain, hemic and lymphatic diseases, FANCD2, Animals, Humans, Monoubiquitination, Molecular Biology, biology, Fanconi Anemia Complementation Group D2 Protein, Cell Cycle, Ubiquitination, Articles, Cell Biology, Chromatin, Ubiquitin ligase, Cell biology, Biochemistry, Ubiquitin-Conjugating Enzymes, biology.protein, Chickens, DNA Damage, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3c33d5d00ed16c2249cca27a10751aTest
https://doi.org/10.1128/mcb.00504-07Test

المؤلفون: Frederic Langevin, Mioko Ohzeki, Laura J. Simpson, Julian E. Sale, Hendrik J. Kuiken, Wojciech Niedzwiedz, Ketan J. Patel, Minoru Takata, Paul E. Pace, Vibe H. Oestergaard

المصدر: Molecular Cell

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, DNA Repair, DNA damage, DNA repair, PROTEINS, Mitomycin, Blotting, Western, Apoptosis, Biology, DNA polymerase delta, Article, hemic and lymphatic diseases, Proliferating Cell Nuclear Antigen, Endopeptidases, Monoubiquitination, Animals, Molecular Biology, Ubiquitin, Fanconi Anemia Complementation Group D2 Protein, Mutagenesis, Cell Cycle, Ubiquitination, nutritional and metabolic diseases, DNA, Cell Biology, Molecular biology, Chromatin, Proliferating cell nuclear antigen, Cross-Linking Reagents, Fanconi Anemia, Gene Expression Regulation, Gene Targeting, Mutation, biology.protein, Mutagenesis, Site-Directed, DNA mismatch repair, Ubiquitin-Specific Proteases, Cisplatin, Chickens, Protein Processing, Post-Translational, DNA Damage, Subcellular Fractions

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bfd5d03dd78296515fb680645a2b4aTest

المؤلفون: Hans Joenje, Ketan J. Patel

المصدر: DNA Repair. 6:885-890

مصطلحات موضوعية: DNA Replication, Genetics, DNA Repair, DNA repair, DNA replication, Context (language use), Cell Biology, Biology, medicine.disease, Biochemistry, Fanconi Anemia Complementation Group Proteins, chemistry.chemical_compound, Fanconi Anemia, chemistry, Fanconi anemia, medicine, Animals, Humans, Molecular Biology, Gene, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb7a08b49e52691ef12554b484a3703Test
https://doi.org/10.1016Test/j.dnarep.2007.02.002