المؤلفون: Céleste Sele, Ewa Krupinska, Anna Andersson Rasmussen, Simon Ekström, Lucas Hultgren, Jiaqi Lou, Frank Kozielski, S. Zoë Fisher, Wolfgang Knecht

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Cancer, Infectious Diseases, Virology, Computational Biology, Covid-19, coronavirus, exoribonuclease, protein–protein interactions, microscale thermophoresis, multi-detection SEC, hydrogen-deuterium exchange mass spectrometry

العلاقة: https://figshare.com/articles/journal_contribution/New_insights_into_complex_formation_by_SARS-CoV-2_nsp10_and_nsp14/25320610Test

الإتاحة: https://doi.org/10.6084/m9.figshare.25320610.v1Test
https://figshare.com/articles/journal_contribution/New_insights_into_complex_formation_by_SARS-CoV-2_nsp10_and_nsp14/25320610Test

المؤلفون: Walport, Louise J., Low, Jason K. K., Matthews, Jacqueline M., Mackay, Joel P.

المصدر: Chemical Society Reviews; 11/21/2021, Vol. 50 Issue 22, p12292-12307, 16p

مصطلحات موضوعية: FLUORIMETRY, FLUORESCENCE resonance energy transfer, ISOTHERMAL titration calorimetry, MASS spectrometry, HYDROGEN-deuterium exchange, MOLECULAR biology, BIOMOLECULES

المؤلفون: Landureau, Maud, Redeker, Virginie, Bellande, Tracy, Eyquem, Stéphanie, Melki, Ronald

المساهمون: Centre National de la Recherche Scientifique (CNRS), Molecular Imaging Research Center Fontenay-aux-Roses (MIRCEN), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), SANOFI Recherche, ANR-17-JPCD-0005,Protest-70,Protecting protein homeostasis in synucleinopathies and tauopathies by modulating the Hsp70/co-chaperone network(2017), ANR-17-JPCD-0002,TransPathND,Intraneuronal transport-related pathways across neurodegenerative diseases(2017), European Project: (grant No 116060),IMPRiND, European Project: 821522,PD-MitoQUANT - H2020-EU.3.1.7. - Innovative Medicines Initiative 2 (IMI2)

المصدر: ISSN: 0021-9258.

مصطلحات موضوعية: alpha-synuclein, protein misfolding, strains, limited proteolysis, hydrogen-deuterium exchange, mass spectrometry, surface mapping, neurodegenerative disease, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: info:eu-repo/grantAgreement//(grant No 116060)/EU/ EU/EFPIA/Innovative Medicines Initiative 2 Joint Undertaking./IMPRiND; info:eu-repo/grantAgreement//821522/EU/A quantitative approach towards the characterisation of mitochondrial dysfunction in Parkinson's disease/PD-MitoQUANT - H2020-EU.3.1.7. - Innovative Medicines Initiative 2 (IMI2); cea-03219237; https://cea.hal.science/cea-03219237Test; https://cea.hal.science/cea-03219237/documentTest; https://cea.hal.science/cea-03219237/file/Landureau%20et%20al%20JBC%202021.pdfTest

الإتاحة: https://doi.org/10.1016/j.jbc.2021.100737Test
https://cea.hal.science/cea-03219237Test
https://cea.hal.science/cea-03219237/documentTest
https://cea.hal.science/cea-03219237/file/Landureau%20et%20al%20JBC%202021.pdfTest

المؤلفون: Masaru Miyagi (229956), Kohei Tanaka (831041), Shinko Watanabe (11649278), Jun Kondo (548450), Taro Kishimoto (6924317)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, hydrogen deuterium exchange, hek293 cell lysates, endogenously expressed mapk14, chemical moieties used, protein stability induced, lc – ms, require covalent modifications, drugs may mask, critical recognition site, 2 , method uses histidine, capturing interacting proteins, methods identify targets, covalent modifications, protein denaturant, ms ), interacting proteins, various concentrations, successfully applied, solid support

العلاقة: https://figshare.com/articles/journal_contribution/Identifying_Protein_Drug_Interactions_in_Cell_Lysates_Using_Histidine_Hydrogen_Deuterium_Exchange/16934066Test

الإتاحة: https://doi.org/10.1021/acs.analchem.1c02283.s001Test

المؤلفون: Guntur Fibriansah (297278), Elisa X. Y. Lim (10184016), Jan K. Marzinek (1773160), Thiam-Seng Ng (10184019), Joanne L. Tan (10184022), Roland G. Huber (109002), Xin-Ni Lim (7405580), Valerie S. Y. Chew (10184025), Victor A. Kostyuchenko (10184028), Jian Shi (141852), Ganesh S. Anand (2813851), Peter J. Bond (688987), James E. Crowe Jr. (8313135), Shee-Mei Lok (115203)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Molecular Biology, Neuroscience, Physiology, Biotechnology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, neutralizing properties, hydrogen deuterium exchange mass sp., virus surface, serotype cross-reactive, dengue virus morphologies, antigenic characteristics, DENV 1, dengue morphology influences neutra., neutralizing activities, bumpy-surfaced particle, DENV 1 E proteins, high-affinity antibody, 1 C 19 epitope, DENV 2 serotypes, 1 C 19, DENV 1 strains

العلاقة: https://figshare.com/articles/journal_contribution/Correlation_coefficient_of_the_fitted_models_to_the_density_maps_/14098320Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009331.s009Test

المؤلفون: Smith, Caroline

المصدر: Theses and Dissertations--Molecular and Cellular Biochemistry

مصطلحات موضوعية: camelid, phage display, antibody engineering, protein purification, confocal microscopy, hydrogen-deuterium exchange, Biochemistry, Laboratory and Basic Science Research, Molecular Biology, Neoplasms

وصف الملف: application/pdf

العلاقة: https://uknowledge.uky.edu/biochem_etds/63Test; https://uknowledge.uky.edu/context/biochem_etds/article/1064/viewcontent/Caroline_Smith_dissertation.pdfTest; https://uknowledge.uky.edu/context/biochem_etds/article/1064/filename/0/type/additional/viewcontent/Supplemental_Table1_Raw_values_for_calculating_local_and_global_KD.xlsxTest; https://uknowledge.uky.edu/context/biochem_etds/article/1064/filename/1/type/additional/viewcontent/RightsLink_Printable_License.pdfTest

الإتاحة: https://doi.org/10.13023/etd.2023.159Test
https://uknowledge.uky.edu/biochem_etds/63Test
https://uknowledge.uky.edu/context/biochem_etds/article/1064/viewcontent/Caroline_Smith_dissertation.pdfTest
https://uknowledge.uky.edu/context/biochem_etds/article/1064/filename/0/type/additional/viewcontent/Supplemental_Table1_Raw_values_for_calculating_local_and_global_KD.xlsxTest
https://uknowledge.uky.edu/context/biochem_etds/article/1064/filename/1/type/additional/viewcontent/RightsLink_Printable_License.pdfTest

المؤلفون: Lukas Uhrik, Kathryn L. Ball, Maciej Parys, David Argyle, Chris Nortcliffe, Barbara C. Ruetgen, Umesh Kalathiya, Borivoj Vojtesek, Pavlína Zatloukalová, Marta Nekulova, Mikolaj Kocikowski, Małgorzata Lisowska, Lenka Hernychová, Jakub Faktor, Ted R. Hupp, Robin Fåhraeus, Petr Müller

المصدر: Uhrik, L, Hernychova, L, Muller, P, Kalathiya, U, Lisowska, M M, Kocikowski, M, Parys, M, Faktor, J, Nekulova, M, Nortcliffe, C, Zatloukalova, P, Ruetgen, B, Fahraeus, R, Ball, K L, Argyle, D J, Vojtesek, B & Hupp, T 2021, ' Hydrogen Deuterium Exchange Mass Spectrometry identifies the dominant paratope in CD20 antigen binding to the NCD1.2 monoclonal antibody ', Biochemical Journal, vol. 478, no. 1, pp. 99-120 . https://doi.org/10.1042/BCJ20200674Test
Biochemical Journal

مصطلحات موضوعية: Protein Engineering, Biochemistry, Molecular Bases of Health & Disease, law.invention, 0302 clinical medicine, Structural Biology, Tandem Mass Spectrometry, law, Comparative medicine, Diagnostics & Biomarkers, Research Articles, Cancer, 0303 health sciences, Molecular Interactions, biology, Chemistry, Antibodies, Monoclonal, IgG binding, 030220 oncology & carcinogenesis, Recombinant DNA, Antibody, Immunoglobulin Heavy Chains, medicine.drug_class, Recombinant Fusion Proteins, Omics, Hydrogen Deuterium Exchange-Mass Spectrometry, lymphoma, chemical and pharmacologic phenomena, Monoclonal antibody, Immunoglobulin light chain, 03 medical and health sciences, hydrogen deuterium exchange mass spectrometry, Dogs, Antigen, Peptide Library, Cell Line, Tumor, medicine, Animals, Humans, CD20, Amino Acid Sequence, Molecular Biology, 030304 developmental biology, Cell Biology, Antigens, CD20, Molecular biology, Kinetics, monoclonal antibody, Immunoglobulin G, biology.protein, hydrogen deuterium, Immunoglobulin Light Chains, exchange mass spectrometry, Hydrogen–deuterium exchange, Paratope, Binding Sites, Antibody, comparative medicine, Chromatography, Liquid

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fb429b05c2a88b64c8dd71f33cada0Test
https://doi.org/10.1042/bcj20200674Test

المؤلفون: Neel H. Shah, Christine L. Gee, John Kuriyan, Jean M. Badroos, Helen T. Hobbs, Susan Marqusee

المصدر: Protein Science : A Publication of the Protein Society

مصطلحات موضوعية: Protein Conformation, alpha-Helical, Conformational change, Full‐Length Papers, T-Lymphocytes, Genetic Vectors, Gene Expression, Syk, chemical and pharmacologic phenomena, Adaptive Immunity, Molecular Dynamics Simulation, Crystallography, X-Ray, SH2 domain, Biochemistry, Full‐Length Paper, evolution, Immunoreceptor tyrosine-based activation motif, Escherichia coli, Animals, Humans, Syk Kinase, Protein Interaction Domains and Motifs, Cloning, Molecular, Tyrosine, Molecular Biology, B-Lymphocytes, Binding Sites, ZAP-70 Protein-Tyrosine Kinase, Chemistry, conformational landscape, hydrogen–deuterium exchange mass spectrometry, tyrosine kinase signaling, Deuterium Exchange Measurement, hemic and immune systems, Biological Evolution, Recombinant Proteins, Protein kinase domain, protein dynamics, Biophysics, Phosphorylation, Protein Conformation, beta-Strand, Tyrosine kinase, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838256900e2374647a4621bc4fc68d20Test
https://doi.org/10.1002/pro.4199Test

المؤلفون: Lijun Zhou, Mehwish Iftikhar, Wang Defu, Yinghong Lu, Min Zhou

المصدر: International Journal of Biological Macromolecules. 187:350-360

مصطلحات موضوعية: Conformational change, Chemistry, Binding protein, Binding properties, General Medicine, Periplasmic space, Mass spectrometry, Biochemistry, Molecular dynamics, Structural Biology, Helix, Biophysics, Hydrogen–deuterium exchange, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::dd3c264c9940a5fbd9375af8a25a56c6Test
https://doi.org/10.1016/j.ijbiomac.2021.07.120Test

المؤلفون: Shuaihua Gao, Wenju Zhang, Samuel L. Barrow, Anthony T. Iavarone, Judith P. Klinman

المصدر: The Journal of biological chemistry, vol 298, iss 9

مصطلحات موضوعية: Biochemistry & Molecular Biology, Adenosine, Adenosine Deaminase, Protein Conformation, conformational landscape, protein flexibility, Temperature, Proteins, Deuterium Exchange Measurement, thermal activation, temperature-dependent hydrogen deuterium exchange, Cell Biology, Biological Sciences, Deuterium, Ligands, Biochemistry, Medical and Health Sciences, Chemical Sciences, Molecular Biology, Pentostatin

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7ba7ab46b3f6e76f96799de81f7e3bTest
https://escholarship.org/uc/item/13w120tkTest