المؤلفون: Winkler, Martin, Duan, Jifu, Rutz, Andreas, Felbek, Christina, Scholtysek, Lisa, Lampret, Oliver, Jaenecke, Jan, Apfel, Ulf-Peter, Gilardi, Gianfranco, Valetti, Francesca, Fourmond, Vincent, Hofmann, Eckhard, Léger, Christophe, Happe, Thomas

المساهمون: Ruhr University Bochum = Ruhr-Universität Bochum (RUB), Bioénergétique et Ingénierie des Protéines (BIP ), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Università degli studi di Torino = University of Turin (UNITO), ANR-12-BS08-0014,ECCHYMOSE,Etudes d'hydrogénases à Fer par électrochimie: mécanisme et optimisation pour la photoproduction d'hydrogène(2012), ANR-14-CE05-0010,HEROS,Hydrogénases résistantes à l'Oxygène(2014), ANR-11-IDEX-0001,Amidex,INITIATIVE D'EXCELLENCE AIX MARSEILLE UNIVERSITE(2011)

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: Enzyme mechanisms, Enzymes, X-ray crystallography, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: hal-03129104; https://hal.science/hal-03129104Test; https://hal.science/hal-03129104/documentTest; https://hal.science/hal-03129104/file/s41467-020-20861-2.pdfTest

الإتاحة: https://doi.org/10.1038/s41467-020-20861-2Test
https://hal.science/hal-03129104Test
https://hal.science/hal-03129104/documentTest
https://hal.science/hal-03129104/file/s41467-020-20861-2.pdfTest

المؤلفون: Kanaan, Joanne, Raj, Saurabh, Decourty, Laurence, Saveanu, Cosmin, Croquette, Vincent, Le Hir, Hervé

المساهمون: Institut de biologie de l'ENS Paris (IBENS), Département de Biologie - ENS Paris, École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Statistique de l'ENS (LPS), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Leipzig University / Universität Leipzig, Génétique des Interactions macromoléculaires / Genetics of Macromolecular Interactions, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), This study was supported by the ANR CLEANMD grant (ANR-14-CE10-0014) from the French Agence Nationale de la Recherche to C.S., V.C., and H.L.H., by the program « Investissements d’Avenir » launched by the French Government and implemented by ANR (ANR–10–LABX-54 MEMOLIFE and ANR–10–IDEX–0001–02 PSL* Research University) to J.K. and H.L.H., by the European Research Council grant Magreps 267862 to V.C. and S.R., by the Fondation ARC pour la recherche sur le cancer PhD fellowship to J.K., and by continuous financial support from the Centre National de Recherche Scientifique, the Ecole Normale Supérieure and the Institut National de la Santé et de la Recherche Médicale, France., ANR-14-CE10-0014,CLEANMD,Mécanismes moléculaires et impact de la voie de dégradation des ARNm nonsense (NMD) sur le transcriptome eucaryote.(2014), ANR-10-IDEX-0001,PSL,Paris Sciences et Lettres(2010), European Project: 267862,EC:FP7:ERC,ERC-2010-AdG_20100224,MAGREPS(2011)

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: Enzyme mechanisms, Single-molecule biophysics, RNA-binding proteins, DNA-binding proteins, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30218034; info:eu-repo/grantAgreement/EC/FP7/267862/EU/High-resolution tweezers for DNA replication and sequence identification/MAGREPS; hal-01878957; https://hal.sorbonne-universite.fr/hal-01878957Test; https://hal.sorbonne-universite.fr/hal-01878957/documentTest; https://hal.sorbonne-universite.fr/hal-01878957/file/s41467-018-06313-y.pdfTest; PUBMED: 30218034

الإتاحة: https://doi.org/10.1038/s41467-018-06313-yTest
https://hal.sorbonne-universite.fr/hal-01878957Test
https://hal.sorbonne-universite.fr/hal-01878957/documentTest
https://hal.sorbonne-universite.fr/hal-01878957/file/s41467-018-06313-y.pdfTest

المؤلفون: Wiktor, Maciej, Weichert, Dietmar, Howe, Nicole, Huang, Chia-Ying, Olieric, Vincent, Boland, Coilín, Bailey, Jonathan, Vogeley, Lutz, Stansfeld, Phillip J, Buddelmeijer, Nienke, Wang, Meitian, Caffrey, Martin

المساهمون: Trinity College Dublin, Paul Scherrer Institute (PSI), University of Oxford, Biologie et Génétique de la Paroi bactérienne - Biology and Genetics of Bacterial Cell Wall (BGPB), Institut Pasteur Paris (IP), The work was funded by Science Foundation Ireland grant 12/IA/1255. M.W. was supported, in part, by Swiss National Science Foundation Early Postdoc. Mobility fellowship grant P2BSP3_15254. D.W. was supported, in part, by the Deutsche Forschungsgemeinschaft (German Research Foundation). P.J.S. was supported by BBSRC grant BB/I019855/1. MDS were performed using the Irish Centre for High-End Computing (ICHEC) facilities., We thank past (T. El Arnaout, G. Heinecke, E. Hurley, T. Kwan) and present members of the MS&FB group for their assorted contributions to this study. The assistance and support of beamline scientists at the Swiss Light Source (X06SA and X10SA), Diamond Light Source (I24) and the Advanced Photon Source (23-ID) are acknowledged

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: Enzyme mechanisms, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28675161; pasteur-01561000; https://pasteur.hal.science/pasteur-01561000Test; https://pasteur.hal.science/pasteur-01561000/documentTest; https://pasteur.hal.science/pasteur-01561000/file/Wiktor2017_Lnt-structure.pdfTest; PUBMED: 28675161; PUBMEDCENTRAL: PMC5500888

الإتاحة: https://doi.org/10.1038/ncomms15952Test
https://pasteur.hal.science/pasteur-01561000Test
https://pasteur.hal.science/pasteur-01561000/documentTest
https://pasteur.hal.science/pasteur-01561000/file/Wiktor2017_Lnt-structure.pdfTest

المؤلفون: Jeroen S. Dickschat, Houchao Xu

المصدر: Chembiochem

مصطلحات موضوعية: Stereochemistry, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Biochemistry, Mass Spectrometry, Terpene, chemistry.chemical_compound, enzyme mechanisms, Fragmentation (mass spectrometry), Molecular Biology, isotopes, 010405 organic chemistry, Chemistry, Communication, Organic Chemistry, Total synthesis, Stereoisomerism, Mass spectrometric, Streptomyces, Communications, 0104 chemical sciences, Cyclization, Molecular Medicine, Diterpenes, biosynthesis, Diterpene, terpenes, Streptomyces violens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c082a2e78699d5aeb98fcbfe25cd4070Test
https://doi.org/10.1002/cbic.202000682Test

المؤلفون: Bögeholz, Lena A. K., Mercier, Evan, Wintermeyer, Wolfgang, Rodnina, Marina V.

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Translation, 0303 health sciences, Multidisciplinary, Molecular biology, Escherichia coli Proteins, Science, Biochemistry, Article, Amidohydrolases, Kinetics, 03 medical and health sciences, 0302 clinical medicine, Protein Biosynthesis, Enzyme mechanisms, Escherichia coli, Medicine, Protein Processing, Post-Translational, Ribosomes, 030217 neurology & neurosurgery, Post-translational modifications, 030304 developmental biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98aa9a443265ba7b86696206528e5bfeTest
https://hdl.handle.net/21.11116/0000-000C-A855-721.11116/0000-000C-A857-5Test

المؤلفون: David Ron, Yahui Yan, Heather P. Harding

المساهمون: Yan, Yahui [0000-0001-6934-9874], Harding, Heather P. [0000-0002-7359-7974], Ron, David [0000-0002-3014-5636], Apollo - University of Cambridge Repository

المصدر: Nature Structural & Molecular Biology

مصطلحات موضوعية: Models, Molecular, Hydrolases, Protein subunit, 631/535/1258/1259, Phosphatase, 13/106, CHO Cells, 13/109, Crystallography, X-Ray, 631/45/173, 631/45/607/1164, Dephosphorylation, 82/80, chemistry.chemical_compound, Phosphoserine, eIF-2 Kinase, Cricetulus, Structural Biology, Stress, Physiological, Catalytic Domain, Protein Phosphatase 1, Integrated stress response, Animals, Humans, Phosphorylation, Molecular Biology, 14/35, 82/83, biology, 82/16, Kinase, 9/10, Cryoelectron Microscopy, 101/28, article, Active site, Reproducibility of Results, Actins, Cell biology, 13/31, chemistry, 631/80/458/1733, Enzyme mechanisms, 14/63, biology.protein

وصف الملف: application/pdf; text/xml; application/zip

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3922eb945c18d759d1bcc706e6bfaac5Test
https://www.repository.cam.ac.uk/handle/1810/329189Test

المؤلفون: B. Leticia Rodriguez, Priyam Banerjee, Neus Bota-Rabassedas, Hou Fu Guo, Yulong Chen, Gregg B. Fields, Jiang Yu, Chi Lin Tsai, Jonathan M. Kurie, Chad J. Creighton, Xiaoyan Wang, George N. Phillips, Masahiko Terajima, John A. Tainer, Xiaochao Tan, Xin Liu, Mitsuo Yamauchi, Michal Tokmina-Roszyk, Don L. Gibbons, Kevin N. Dalby, Mitchell D. Miller, Roma Stawikowska, Ju-Hoon Lee

المصدر: Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Cancer microenvironment, 0301 basic medicine, Gene isoform, Lung Neoplasms, QH301-705.5, Lysyl hydroxylase, Lysine, Glycobiology, Medicine (miscellaneous), Adenocarcinoma of Lung, macromolecular substances, Article, General Biochemistry, Genetics and Molecular Biology, Metastasis, Mice, 03 medical and health sciences, Exon, 0302 clinical medicine, medicine, Animals, Biology (General), chemistry.chemical_classification, biology, medicine.disease, Molecular biology, 030104 developmental biology, Enzyme, chemistry, Glucosyltransferases, 030220 oncology & carcinogenesis, Enzyme mechanisms, Cancer cell, Disease Progression, biology.protein, Adenocarcinoma, Molecular modelling, General Agricultural and Biological Sciences

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a6065eea048d2a61c246ee53a0dfd6Test
https://doi.org/10.1038/s42003-021-01982-wTest

المؤلفون: Rebecca J. M. Goss, Joanna C. Sadler, Sabine Grüschow, Peter Sharratt

المساهمون: BBSRC, European Research Council, University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex, University of St Andrews. School of Chemistry, University of St Andrews. EaSTCHEM

المصدر: Chembiochem
Grüschow, S, Sadler, J C, Sharratt, P J & Goss, R J M 2019, ' Phenylalanine meta-hydroxylase : A single residue mediates mechanistic control of aromatic amino acid hydroxylation ', ChemBioChem, vol. 21 . https://doi.org/10.1002/cbic.201900320Test

مصطلحات موضوعية: Enzyme mechanism, NIH shift, biocatalysis, Stereochemistry, QH301 Biology, NDAS, Phenylalanine, Electrophilic aromatic substitution, 010402 general chemistry, Hydroxylation, 01 natural sciences, Biochemistry, meta-tyrosine biosynthesis, QH301, chemistry.chemical_compound, Amino Acids, Aromatic, Stereospecificity, enzyme mechanisms, Aromatic amino acids, Meta-tyrosine biosynthesis, QD, Hydroxylase, Tyrosine, 1,2-hydride (NIH) shift, Molecular Biology, chemistry.chemical_classification, Full Paper, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Phenylalanine Hydroxylase, Full Papers, QD Chemistry, hydroxylases, Streptomyces, 0104 chemical sciences, Amino acid, chemistry, Biocatalysis, Molecular Medicine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6406aa5503c29840328c2fb09a709bbTest
http://europepmc.org/articles/PMC7027792Test

المؤلفون: A. Rod Merrill, Kayla A. Heney, Madison Turner

المصدر: Bioscience Reports

مصطلحات موضوعية: 0301 basic medicine, In silico, 030106 microbiology, Biophysics, protein-protein interactions, medicine.disease_cause, Biochemistry, Microbiology, Protein–protein interaction, 03 medical and health sciences, Intergenic region, enzyme mechanisms, Structural Biology, Host-Microbe Interactions, medicine, honey bee diseases, Homology modeling, Molecular Biology, Research Articles, chemistry.chemical_classification, Molecular Interactions, Toxin, Cell Biology, N-terminus, macrophage cell entry, 030104 developmental biology, Enzyme, chemistry, ADP-ribosyltransferase toxins, Enzymology, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ffa71e8a75b4acff6b085a0104fc1eTest
http://europepmc.org/articles/PMC7789906Test

المؤلفون: Sonia S. Shah, Sharad Kumar

المساهمون: Shah, Sonia Shalini, Kumar, Sharad

المصدر: Cell Death Differ

مصطلحات موضوعية: 0301 basic medicine, HECT domain, Saccharomyces cerevisiae Proteins, Ubiquitin-Protein Ligases, Cellular functions, Review Article, macromolecular substances, Saccharomyces cerevisiae, Ubiquitin-conjugating enzyme, 03 medical and health sciences, enzyme mechanisms, 0302 clinical medicine, Ubiquitin, Animals, Humans, Molecular Biology, Adaptor Proteins, Signal Transducing, biology, Signal transducing adaptor protein, Correction, Cell Biology, Cell biology, 030104 developmental biology, 030220 oncology & carcinogenesis, Ubiquitin-Conjugating Enzymes, biology.protein, Calcium, experimental models of disease, Signalling pathways, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0f1be473f690678cdde576b00cf279Test
https://pubmed.ncbi.nlm.nih.gov/33483704Test