نتائج البحث - "Biomedical Science Research Group"

1

Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential

المؤلفون: Katherine Staines, Richard O.C. Oreffo, Roger Emery, Sumeet Mahajan, Aikta Sharma, Claire E. Clarkin, Alice Goring, Andrew A. Pitsillides

المصدر: Matrix Biology Plus, Vol 5, Iss, Pp-(2020)
Matrix Biology Plus

مصطلحات موضوعية: Biomedical Science Research Group, Histology, ACP, amorphous calcium phosphate, Biophysics, chemistry.chemical_element, Calcium, Biochemistry, Mineralization (biology), Article, OB, osteoblast, symbols.namesake, Hydroxyproline, chemistry.chemical_compound, CCEC, collagenase-collagenase-EDTA-collagenase, OCP, octacalcium phosphate, Genetics, medicine, Viability assay, Amorphous calcium phosphate, lcsh:QH301-705.5, Molecular Biology, Poly-l-lysine, Osteoblast, Cell Biology, ALP, tissue non-specific alkaline phosphatase, QD Chemistry, PCA, principle component analysis, VEGF, vascular endothelial growth factor, VEGF, MV, matrix vesicles, ECM, extracellular matrix, Cell biology, CAP, carbonated apatite, PLL, poly-l-lysine, Ageing, medicine.anatomical_structure, RT-qPCR, reverse transcription-quantiative PCR, lcsh:Biology (General), chemistry, Health, HBSS, Hank's balanced salt solution, Raman spectroscopy, HA, hydroxyapatite, Osteoblast mineralization, symbols, 543 Analytical chemistry, Alkaline phosphatase, Raman spectroscopy, poly-L-lysine, osteoblast mineralization, VEGF

وصف الملف: text; Word

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1148f100a7b32f1fee138e3f75a676Test
https://eprints.soton.ac.uk/436688Test/

2

A distinctive patchy osteomalacia characterises Phospho1 -deficient mice

المؤلفون: Katherine Staines, Behzad Javaheri, Alan Boyde, José Luis Millán, Colin Farquharson, Andrew A. Pitsillides

المصدر: Boyde, A, Staines, K, Javaheri, B, Millan, J-L, Pitsillides, A A & Farquharson, C 2017, ' A distinctive patchy osteomalacia characterises Phospho1 deficient mice ', Journal of Anatomy, vol. 231, no. 2, pp. 298-308 . https://doi.org/10.1111/joa.12628Test

مصطلحات موضوعية: Male, Biomedical Science Research Group, 0301 basic medicine, Histology, biomineralisation, Spontaneous Fractures, Phosphatase, osteomalacia, PHOSPHO1, Pronase, Matrix (biology), Bone and Bones, Mice, 03 medical and health sciences, Calcification, Physiologic, 571 Physiology & related subjects, Sports sciences, Deficient mouse, medicine, Animals, osteoid, backscattered-electron imaging, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Mice, Knockout, QP Physiology, Osteomalacia, Chemistry, Original Articles, Cell Biology, Anatomy, medicine.disease, Phosphoric Monoester Hydrolases, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Anatomical sites, Health, Developmental Biology, Blood vessel

وصف الملف: PDF; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26234e9333ee24b67f96f079d4b3ce7Test
https://doi.org/10.1111/joa.12628Test

3

Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia

المؤلفون: Miguel A. S. Martín-Aragón Baudel, Jennifer Fraser, Amy V. Poole, Mark G. Darlison, Mick Rae

المساهمون: Simos, George

المصدر: PLoS ONE, Vol 12, Iss 10, p e0185664 (2017)
PLoS ONE
Baudel, M A S M-A, Rae, M T, Darlison, M G, Poole, A & Fraser, J 2017, ' Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia ', PLoS ONE, vol. 12, no. 10, e0185664 . https://doi.org/10.1371/journal.pone.0185664Test

مصطلحات موضوعية: Biomedical Science Research Group, 0301 basic medicine, Pulmonology, Cellular differentiation, Retinoic acid, lcsh:Medicine, Vimentin, Vascular Medicine, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Neural Stem Cells, Basic Helix-Loop-Helix Transcription Factors, Medicine and Health Sciences, Hypoxia, lcsh:Science, Neurons, Multidisciplinary, Neuronal Morphology, Protein Stability, Cell Differentiation, Endoplasmic Reticulum Stress, Adaptation, Physiological, Cell Hypoxia, Cell biology, Stroke, Hypoxia-inducible factors, Neurology, RC Internal medicine, Signal transduction, medicine.symptom, Neuronal Differentiation, Signal Transduction, Research Article, Neurite, 616.81 Stroke, Cerebrovascular Diseases, Immunoblotting, Molecular Probe Techniques, Biology, Real-Time Polymerase Chain Reaction, Research and Analysis Methods, 03 medical and health sciences, Stroke, acute hypoxia, neuronal adaptation, Oxygen homeostasis, Medical Hypoxia, medicine, Animals, Humans, Molecular Biology Techniques, Molecular Biology, Ischemic Stroke, lcsh:R, Biology and Life Sciences, Proteins, Cell Biology, Hypoxia (medical), Rats, Cytoskeletal Proteins, 030104 developmental biology, chemistry, nervous system, Cellular Neuroscience, Immunology, biology.protein, lcsh:Q, 030217 neurology & neurosurgery, Developmental Biology, Neuroscience

وصف الملف: PDF; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc44a01f375b36e9429a1e8fd2d24c2eTest
http://europepmc.org/articles/PMC5624621?pdf=renderTest

4

MEPE is a novel regulator of growth plate cartilage mineralization

المؤلفون: Lesya Zelenchuk, Neil Mackenzie, Katherine Staines, Peter S. N. Rowe, Vicky E MacRae, Colin Farquharson, Claire E. Clarkin

المصدر: Bone
Staines, K, Mackenzie, N C W, Clarkin, C E, Zelenchuk, L, Rowe, P S, MacRae, V E & Farquharson, C 2012, ' MEPE is a novel regulator of growth plate cartilage mineralization ', Bone, vol. 51, no. 3, pp. 418-430 . https://doi.org/10.1016/j.bone.2012.06.022Test

مصطلحات موضوعية: Biomedical Science Research Group, Physiology, Endocrinology, Diabetes and Metabolism, Bone Matrix, ASARM, Mineralization (biology), Extracellular matrix, Mice, 0302 clinical medicine, Phosphorylation, Peptide sequence, Metatarsal Bones, Extracellular Matrix Proteins, 0303 health sciences, Original Full Length Article, Endothelial stem cell, medicine.anatomical_structure, Health, RC Internal medicine, Growth plate, Mineralization, Histology, Molecular Sequence Data, 030209 endocrinology & metabolism, Cartilage metabolism, Biology, Chondrocyte, 03 medical and health sciences, Calcification, Physiologic, 616 Diseases, Extracellular, medicine, Animals, Amino Acid Sequence, RNA, Messenger, Glycoproteins, 030304 developmental biology, MEPE, Tibia, Alkaline Phosphatase, Phosphoproteins, Molecular biology, Mice, Inbred C57BL, Cartilage, Gene Expression Regulation, MEPE, ASARM, Growth plate, Mineralization, Chondrocyte, Peptides, Biomarkers

وصف الملف: PDF; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689295ea2bcf59dd748abf3b7cd11c6cTest
https://doi.org/10.1016/j.bone.2012.06.022Test

5

The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium

المؤلفون: Christopher Haslett, Paula E. Beaumont, Robert E. W. Hancock, John R. W. Govan, A. John Simpson, Donald J. Davidson, Annie Mackellar, Thomas S. Wilkinson, Peter G. Barlow, Celine Cosseau

المصدر: Barlow, P G, Beaumont, P E, Cosseau, C, Mackellar, A, Wilkinson, T S, Hancock, R E W, Haslett, C, Govan, J R W, Simpson, A J & Davidson, D J 2010, ' The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium ', American Journal of Respiratory Cell and Molecular Biology, vol. 43, no. 6, pp. 692-702 . https://doi.org/10.1165/rcmb.2009-0250OCTest

مصطلحات موضوعية: Biomedical Science Research Group, antimicrobial peptide, medicine.medical_treatment, Clinical Biochemistry, Apoptosis, Cell Communication, Epithelium, Cathelicidin, innate immunity, bcl-2-Associated X Protein, Membrane Potential, Mitochondrial, biology, apoptosis, Cytochromes c, Articles, Endocytosis, Cell biology, Caspases, Pseudomonas aeruginosa, medicine.symptom, Pulmonary and Respiratory Medicine, Programmed cell death, Cell signaling, Inflammation, Bronchi, DNA Fragmentation, Centre for Nano Safety, Microbiology, Bcl-2-associated X protein, Bacterial Proteins, Cathelicidins, Pseudomonas, medicine, Humans, Pseudomonas Infections, Microbiology Research Group, Molecular Biology, Innate immune system, Epithelial Cells, Cell Biology, RF Otorhinolaryngology, Enzyme Activation, Fimbriae, Bacterial, biology.protein, Respiratory epithelium, 616.2 Respiratory diseases, cationic host defense peptide, Antimicrobial Cationic Peptides

وصف الملف: PDF; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5080eb848c4633c6bced05827a4a7beTest

6

Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages

المؤلفون: Annie Mackellar, Adriano G. Rossi, Christopher Haslett, Pieter S. Hiemstra, Mohini Gray, Donald J. Davidson, Åse Björstad, Johan Bylund, Hsin-Ni Li, A. John Simpson, Peter G. Barlow, James Conlon

المصدر: Li, H-N, Barlow, P G, Bylund, J, Mackellar, A, Bjorstad, A, Conlon, J, Hiemstra, P S, Haslett, C, Gray, M, Simpson, A J, Rossi, A G & Davidson, D J 2009, ' Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages ', Journal of Leukocyte Biology, vol. 86, no. 4, pp. 891-902 . https://doi.org/10.1189/jlb.0209050Test
Journal of Leukocyte Biology

مصطلحات موضوعية: Biomedical Science Research Group, Necrosis, antimicrobial peptide, Neutrophils, medicine.medical_treatment, Phagocytosis, Immunology, Apoptosis, Inflammation, Biology, Biochemistry, Cell Degranulation, Centre for Nano Safety, Cathelicidin, Proinflammatory cytokine, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, 616 Diseases, Cathelicidins, medicine, Humans, Macrophage, Immunology and Allergy, Microbiology Research Group, Efferocytosis, Molecular Biology, innate immunity, 030304 developmental biology, efferocytosis, 0303 health sciences, Innate immune system, Chemistry, Inflammation, Extracellular Mediators, & Effector Molecules, Macrophages, Hematology, Cell Biology, 3. Good health, Cell biology, inflammation, RB Pathology, cationic host defense peptide, medicine.symptom, 030215 immunology