نتائج البحث - "Alan J. Warren"

1

Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1

المؤلفون: Michael Prattes, Irina Grishkovskaya, Victor-Valentin Hodirnau, Christina Hetzmannseder, Gertrude Zisser, Carolin Sailer, Vasileios Kargas, Mathias Loibl, Magdalena Gerhalter, Lisa Kofler, Alan J. Warren, Florian Stengel, David Haselbach, Helmut Bergler

المساهمون: Prattes, Michael [0000-0002-2526-9896], Grishkovskaya, Irina [0000-0003-0164-9373], Hodirnau, Victor-Valentin [0000-0003-3904-947X], Kofler, Lisa [0000-0002-8894-8802], Warren, Alan J [0000-0001-9277-4553], Stengel, Florian [0000-0003-1447-4509], Haselbach, David [0000-0002-5276-5633], Bergler, Helmut [0000-0002-7724-309X], Apollo - University of Cambridge Repository

مصطلحات موضوعية: Adenosine Triphosphatases, Ribosomal Proteins, Saccharomyces cerevisiae Proteins, Structural Biology, ddc:570, ATPases Associated with Diverse Cellular Activities, Saccharomyces cerevisiae, Ribosome Subunits, Large, Eukaryotic, Molecular Biology, Ribosomes

وصف الملف: application/pdf; application/zip; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd07e03705a95145eca7d2002ac8dbb5Test
https://www.repository.cam.ac.uk/handle/1810/341317Test

2

Direct targeted therapy for MLL-fusion-driven high-risk acute leukaemias

المؤلفون: Sandra Cantilena, Luca Gasparoli, Deepali Pal, Olaf Heidenreich, Jan‐Henning Klusmann, Joost H. A. Martens, Alexandre Faille, Alan J. Warren, Mawar Karsa, Ruby Pandher, Klaartje Somers, Owen Williams, Jasper de Boer

المساهمون: Warren, Alan J [0000-0001-9277-4553], de Boer, Jasper [0000-0002-3220-8776], Apollo - University of Cambridge Repository, Warren, Alan [0000-0001-9277-4553]

المصدر: Clinical and Translational Medicine, 12, 1-19
Clinical and Translational Medicine, 12, 6, pp. 1-19

مصطلحات موضوعية: Leukemia, Oncogene Proteins, Fusion, precision medicine, MLL-fusion, Medicine (miscellaneous), Infant, Apoptosis, A300, C700, targeted therapy, MLL‐fusion, RESEARCH ARTICLES, Epigenesis, Genetic, RESEARCH ARTICLE, hemic and lymphatic diseases, leukaemia, Acute Disease, Molecular Medicine, Humans, mouse models, Child, Molecular Biology, neoplasms, Cell Proliferation

وصف الملف: application/pdf; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a8fc905ec8865730951eb87ee2a90fTest
https://www.repository.cam.ac.uk/handle/1810/339424Test

3

DNA-repair enzyme turns to translation

المؤلفون: Alan J. Warren

المساهمون: Warren, Alan [0000-0001-9277-4553], Apollo - University of Cambridge Repository

وصف الملف: application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906211929df5e55e5b0b3f4344c8495cTest
https://www.repository.cam.ac.uk/handle/1810/304370Test

4

1020 – HEMATOPOIETIC STEM CELL CLONAL TRACKING BY WHOLE GENOME SEQUENCING IDENTIFIES MULTIPLE INDEPENDENT SOMATIC GENETIC RESCUE MECHANISMS IN BONE MARROW FAILURE DISORDERS

المؤلفون: Nina F. Øbro, David G. Kent, E. Joanna Baxter, Anna Clay, Alan J. Warren, Peter J. Campbell, Megan Davies, Heather E. Machado

المصدر: Experimental Hematology. 88:S24

مصطلحات موضوعية: Genetics, Whole genome sequencing, Cancer Research, Mutation, education.field_of_study, Population, Hematopoietic stem cell, Cell Biology, Hematology, Biology, medicine.disease_cause, Germline, medicine.anatomical_structure, medicine, Progenitor cell, Stem cell, education, Molecular Biology, Gene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e68d871d1aa80e1fa65e5ccdedf226dcTest
https://doi.org/10.1016Test/j.exphem.2020.09.019

5

A new system for naming ribosomal proteins

المصدر: Current opinion in structural biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de6837a84a38a357e2a453f8751cca3Test
https://doi.org/10.1016Test/j.sbi.2014.01.002

6

Aberrant 3′ oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia

المؤلفون: Paul J. Simpson, Adam Shlien, Frank R. Bowler, Christine Hilcenko, Andrew J. Finch, Alan J. Warren, Michael Kirwan, Mark J. Churcher, Peter J. Campbell, Inderjeet Dokal, Li Jin, Len C. Packman

المصدر: Blood. 121:1028-1038

مصطلحات موضوعية: Models, Molecular, Spliceosome, Neutropenia, Molecular Sequence Data, Immunology, Saccharomyces cerevisiae, Biology, Crystallography, X-Ray, medicine.disease_cause, Biochemistry, Cell Line, Adenine nucleotide, Catalytic Domain, RNA, Small Nuclear, Exoribonuclease, medicine, Humans, Amino Acid Sequence, RNA Processing, Post-Transcriptional, 3' Untranslated Regions, Uridine, Gene, Mutation, Oligoribonucleotides, Base Sequence, Models, Genetic, Sequence Homology, Amino Acid, Adenine Nucleotides, Phosphoric Diester Hydrolases, Reverse Transcriptase Polymerase Chain Reaction, Three prime untranslated region, Genetic Complementation Test, RNA, Cell Biology, Hematology, Molecular biology, Skin Abnormalities, Spliceosomes, Small nuclear RNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df48338fee8e59c102f61e4d28fedb56Test
https://doi.org/10.1182/blood-2012-10-461491Test

7

Shwachman-Bodian-Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs

المؤلفون: Mohamad A. Zaini, Kyungmin In, Alan J. Warren, Cornelis F. Calkhoven, Christine Müller, Marieke von Lindern

المساهمون: Landsteiner Laboratory, Stem Cell Aging Leukemia and Lymphoma (SALL), Calkhoven, Cornelis F [0000-0001-6318-7210], Apollo - University of Cambridge Repository

المصدر: Nucleic acids research, 44(9), 4134-4146. Oxford University Press
Nucleic acids research, 44(9): 4134-4146
Nucleic Acids Research, 44(9), 4134-4146. Oxford University Press
Nucleic Acids Research

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Untranslated region, Neutrophils, EIF6 RELEASE, Gene Expression, ACUTE MYELOID-LEUKEMIA, Biology, medicine.disease_cause, GENE SBDS, Proto-Oncogene Proteins c-myc, CONTROL REPORTER SYSTEM, 03 medical and health sciences, Cell Line, Tumor, Upstream open reading frame, RIBOSOMAL-SUBUNIT, BINDING, Genetics, medicine, C-MYC, Humans, Lipomatosis, RNA, Messenger, Peptide Chain Initiation, Translational, Bone Marrow Diseases, Regulation of gene expression, Mutation, Ccaat-enhancer-binding proteins, CCAAT-Enhancer-Binding Protein-beta, Gene regulation, Chromatin and Epigenetics, Proteins, Cell Differentiation, Translation (biology), SBDS, rna, protein isoforms, ribosomes, lip, protein deficiency, diamond, messenger, mutation, Molecular biology, Shwachman-Diamond Syndrome, 030104 developmental biology, Gene Expression Regulation, HEMATOPOIETIC STEM, MITOTIC SPINDLE, CELLS, CCAAT-Enhancer-Binding Proteins, Exocrine Pancreatic Insufficiency, 5' Untranslated Regions

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38fd4c0af1cf586eff7cc8894d67a7dTest
https://pure.amc.nl/en/publications/shwachmanbodiandiamond-syndrome-sbds-protein-deficiency-impairs-translation-reinitiation-from-cebp-and-cebp-mrnasTest(740e1151-158a-4305-a900-4a62d50f2047).html

8

Mechanism of eIF6 release from the nascent 60S ribosomal subunit

المؤلفون: David Traynor, Alan J. Warren, Emmanuel Giudice, Li Jin, Robert R. Kay, Christine Hilcenko, Mark J. Churcher, Chi C. Wong, Felix Weis

المساهمون: Department of Haematology, University of Cambridge [UK] (CAM), Cambridge Institute for Medical Research (CIMR), Medical Research Council Laboratory of Molecular Biology, Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), The Wellcome Trust Sanger Institute [Cambridge], Supported by a Federation of European Biochemical Societies Long termFellowship (to FW), Specialist Programme from Bloodwise [12048] (AJW), theMedical Research Council [MC_U105161083] (AJW) and [U105115237] (RRK),Wellcome Trust strategic award to the Cambridge Institute for Medal Research[100140], Tesni Parry Trust (AJW), Ted’s Gang (AJW) and the Cambridge NIHRBiomedical Research Centre., Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Jonchère, Laurent, Hilcenko, Christine [0000-0002-9596-7833], Warren, Alan [0000-0001-9277-4553], Apollo - University of Cambridge Repository

المصدر: Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2015, 22 (11), pp.914-919. ⟨10.1038/nsmb.3112⟩
Nature Structural and Molecular Biology, Nature Publishing Group, 2015, 22 (11), pp.914-919. ⟨10.1038/nsmb.3112⟩

مصطلحات موضوعية: Models, Molecular, Protein subunit, [SDV]Life Sciences [q-bio], Molecular Conformation, Protozoan Proteins, Diseases, Biology, Ribosome, Models, Biological, GTP Phosphohydrolases, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Eukaryotic initiation factor, Humans, Dictyostelium, Eukaryotic Initiation Factors, Peptide Chain Initiation, Translational, Molecular Biology, Ribonucleoprotein, U5 Small Nuclear, 030304 developmental biology, Cancer, 0303 health sciences, Eukaryotic Large Ribosomal Subunit, Cryoelectron Microscopy, Proteins, Ribosomal RNA, SBDS, Ribosome Subunits, Large, Eukaryotic, Peptide Elongation Factors, Molecular biology, Cell biology, [SDV] Life Sciences [q-bio], EIF6, Ribosome Subunits, 030220 oncology & carcinogenesis, RNA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fd2e34e25b40f3115d0b762fdf512dTest
https://pubmed.ncbi.nlm.nih.gov/26581515Test

9

Defective ribosome assembly in Shwachman-Diamond syndrome

المؤلفون: Alan J. Warren, Chi C. Wong, David Traynor, Nicolas Basse, Robert R. Kay

المصدر: Blood. 118:4305-4312

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fded29cca948de2b03025c4a313a930Test
https://doi.org/10.1182/blood-2011-06-353938Test

10

New insights into 5q- syndrome as a ribosomopathy

المؤلفون: Nicola Trim, Jillian L. Barlow, Wendy N. Erber, Alan J. Warren, Lesley F Drynan, Andrew N. J. McKenzie

المصدر: Cell Cycle. 9:4286-4293

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481f05d07d85687fa70366a21b5210e6Test
https://doi.org/10.4161/cc.9.21.13742Test

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