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المؤلفون: Prasad V.L.S. Burra, Deepak K. Lokwani, Kshipra S. Karnik, Ishudeep Singh Narula, Pravin S. Wakte, Aniket P. Sarkate
المصدر: Journal of Biomolecular Structure and Dynamics. 39:5376-5398
مصطلحات موضوعية: Virtual screening, Lung Neoplasms, integumentary system, biology, Chemistry, Allosteric regulation, General Medicine, Triple mutant, ErbB Receptors, Molecular Docking Simulation, T790M, Drug Resistance, Neoplasm, Structural Biology, Carcinoma, Non-Small-Cell Lung, Mutation, Cancer research, biology.protein, Humans, Non small cell, Epidermal growth factor receptor, Protein Kinase Inhibitors, Molecular Biology, Tyrosine kinase, EGFR inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dca1262857426871d50050ba20e810dTest
https://doi.org/10.1080/07391102.2020.1786460Test -
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المؤلفون: Marcin Wierzchowski, Mariusz Kaczmarek, Hanna Piotrowska-Kempisty, Marta Dyszkiewicz-Konwińska, Jadwiga Jodynis-Liebert, Wiesława Kranc, Małgorzata Józkowiak, Piotr Ramlau, Julia Spaczyńska
المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6180, p 6180 (2021)
Volume 22
Issue 12مصطلحات موضوعية: QH301-705.5, gefitinib, Catalysis, Receptor tyrosine kinase, Article, Inorganic Chemistry, Gefitinib, Antineoplastic Combined Chemotherapy Protocols, medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Humans, Epidermal growth factor receptor, Biology (General), Physical and Theoretical Chemistry, QD1-999, Molecular Biology, Spectroscopy, EGFR inhibitors, Cell Proliferation, biology, Chemistry, Organic Chemistry, Cell Cycle, tongue cancer, apoptosis, DMU-214, General Medicine, Cell cycle, Computer Science Applications, Tongue Neoplasms, resveratrol analogue, ErbB Receptors, Gene Expression Regulation, Neoplastic, EGFR inhibitor, Resveratrol, Cancer cell, biology.protein, Cancer research, Phosphorylated Epidermal Growth Factor Receptor, Tyrosine kinase, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc504c58cd37f26d80165dff96a4ebfTest
http://europepmc.org/articles/PMC8226931Test -
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المؤلفون: Yoshikazu Nakamura, Junko Hamamoto, Masatoshi Fujiwara, Tomoko Betsuyaku, Hiroyuki Yasuda, Yosuke Nonaka, Kenzo Soejima
المصدر: Biochemical and Biophysical Research Communications. 503:1330-1334
مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Aptamer, Biophysics, Apoptosis, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Tumor Cells, Cultured, medicine, Humans, Lung cancer, Cytotoxicity, Molecular Biology, Cell Proliferation, EGFR inhibitors, Dose-Response Relationship, Drug, Chemistry, Cell growth, Cancer, Gefitinib, Cell Biology, Aptamers, Nucleotide, medicine.disease, Receptors, Fibroblast Growth Factor, 030104 developmental biology, 030220 oncology & carcinogenesis, embryonic structures, Cancer cell, Cancer research, Fibroblast Growth Factor 2, Drug Screening Assays, Antitumor, Tyrosine kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0052408a8ac93120a58fa9810c8bd58Test
https://doi.org/10.1016/j.bbrc.2018.07.044Test -
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المؤلفون: Daryono H. Tjahjono, Frangky Sangande, Elin Julianti
المصدر: International Journal of Molecular Sciences, Vol 21, Iss 7779, p 7779 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20مصطلحات موضوعية: 0301 basic medicine, dual inhibitor, Databases, Pharmaceutical, Drug Evaluation, Preclinical, Ligands, Tyrosine-kinase inhibitor, lcsh:Chemistry, 0302 clinical medicine, Epidermal growth factor receptor, lcsh:QH301-705.5, Spectroscopy, EGFR inhibitors, biology, Chemistry, General Medicine, Computer Science Applications, ErbB Receptors, Molecular Docking Simulation, Axitinib, VEGFR2, 030220 oncology & carcinogenesis, cardiovascular system, Erlotinib, Pharmacophore, Tyrosine kinase, medicine.drug, ligand-based pharmacophore, medicine.drug_class, EGFR, Antineoplastic Agents, Molecular Dynamics Simulation, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, medicine, Physical and Theoretical Chemistry, Protein Kinase Inhibitors, Molecular Biology, Organic Chemistry, Hydrogen Bonding, molecular docking, Vascular Endothelial Growth Factor Receptor-2, molecular dynamics, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Docking (molecular), Cancer research, biology.protein
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9077a9f9d5cc7f842b1c0811d9942198Test
https://www.mdpi.com/1422-0067/21/20/7779Test -
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المؤلفون: Zahra M. Al-amshany, Manal M. Anwar, Eman S. Nossier, Nada Y. Tashkandi, Ismail M.M. Othman, Mohamed A. M. Gad-Elkareem
المصدر: Bioorganic Chemistry. 114:105078
مصطلحات موضوعية: Models, Molecular, Antifungal Agents, Antineoplastic Agents, Microbial Sensitivity Tests, Pharmacology, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Pyrimidine analogue, Cell Line, Tumor, Drug Discovery, medicine, Humans, Proteus vulgaris, Osimertinib, Epidermal growth factor receptor, Protein Kinase Inhibitors, Molecular Biology, EGFR inhibitors, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Aspergillus fumigatus, Organic Chemistry, Streptococcus, Antimicrobial, Anti-Bacterial Agents, 0104 chemical sciences, ErbB Receptors, 010404 medicinal & biomolecular chemistry, Pyrimidines, Docking (molecular), Mucorales, biology.protein, Pyrazoles, Erlotinib, Drug Screening Assays, Antitumor, Tyrosine kinase, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cd48c2b124f72134db93422dd2865cTest
https://doi.org/10.1016/j.bioorg.2021.105078Test -
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المؤلفون: Rashidi Dzulkeflee, Kok Hoong Leong, Ke Han Tan, Choon Han Heh, Azhar Ariffin, Muhammad Kumayl Abdulwahab
المصدر: Journal of Molecular Structure. 1228:129786
مصطلحات موضوعية: Mutation, 010405 organic chemistry, Chemistry, Kinase, Organic Chemistry, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Molecular biology, respiratory tract diseases, 0104 chemical sciences, Analytical Chemistry, Inorganic Chemistry, T790M, Gefitinib, Cell culture, Epidermal growth factor, medicine, Tyrosine kinase, Spectroscopy, medicine.drug, EGFR inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a442507c90f1575a5d2fc490e800a7aaTest
https://doi.org/10.1016/j.molstruc.2020.129786Test -
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المؤلفون: Cheng-Chu Zeng, Leifu Yang, Peng Liu, Yongjuan Lv, Xuemei Qin, Liming Hu, Zhipeng Li
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:1571-1575
مصطلحات موضوعية: 0301 basic medicine, Morpholines, Clinical Biochemistry, Mutant, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, T790M, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, Quinazoline, Humans, Protein Kinase Inhibitors, Molecular Biology, IC50, Cell Proliferation, EGFR inhibitors, A549 cell, Dose-Response Relationship, Drug, Molecular Structure, Kinase, Organic Chemistry, ErbB Receptors, Molecular Docking Simulation, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Quinazolines, Molecular Medicine, Drug Screening Assays, Antitumor, Tyrosine kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8125837b3f516ed53a37bb866cb5b4b8Test
https://doi.org/10.1016/j.bmcl.2016.02.009Test -
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المصدر: Molecular Informatics. 35:25-35
مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Receptor, ErbB-2, medicine.drug_class, Molecular Dynamics Simulation, medicine.disease_cause, Tyrosine-kinase inhibitor, 03 medical and health sciences, 0302 clinical medicine, Gefitinib, Protein Domains, Structural Biology, Catalytic Domain, Drug Discovery, medicine, Humans, Computer Simulation, Epidermal growth factor receptor, skin and connective tissue diseases, Protein Kinase Inhibitors, neoplasms, EGFR inhibitors, Mutation, Molecular Structure, biology, Organic Chemistry, Hydrogen Bonding, Biological activity, Molecular biology, Computer Science Applications, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, biology.protein, Thermodynamics, Molecular Medicine, Bosutinib, Tyrosine kinase, Protein Binding, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383753cd4685bdbe375a3dc210a3119eTest
https://doi.org/10.1002/minf.201500030Test -
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المؤلفون: Markku Syrjänpää, Natalia Tong-Ochoa, Nicolas Legrand, Kari Kopra, Harri Härmä
المصدر: Analytica Chimica Acta. 897:96-101
مصطلحات موضوعية: Luminescence, ta3111, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, Europium, Fluorescence Resonance Energy Transfer, medicine, Environmental Chemistry, Staurosporine, Phosphorylation, Tyrosine, ta116, Spectroscopy, Enzyme Assays, EGFR inhibitors, Quenching (fluorescence), Kinase, Tyrosine phosphorylation, Molecular biology, High-Throughput Screening Assays, Enzyme Activation, ErbB Receptors, chemistry, Peptides, Tyrosine kinase, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9b55b054740d278070b0adb22b771aTest
https://doi.org/10.1016/j.aca.2015.09.032Test -
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المؤلفون: Timothy Perera, John David Konda, Alessio Noghero, Martina Olivero, Jessica Erriquez, Maria Flavia Di Renzo, Daniele Musiani, Francesco Sassi, Simona Pavan, Erica Torchiaro
المصدر: The FASEB Journal. 28:4055-4067
مصطلحات موضوعية: MAPK/ERK pathway, endocrine system, animal structures, EGFR, medicine.medical_treatment, Blotting, Western, HSP27 Heat-Shock Proteins, Antineoplastic Agents, Apoptosis, Gene mutation, Real-Time Polymerase Chain Reaction, Biochemistry, Research Communications, Targeted therapy, Immunoenzyme Techniques, Mice, Stomach Neoplasms, Tumor Cells, Cultured, Genetics, medicine, Animals, Humans, RNA, Messenger, Epidermal growth factor receptor, RNA, Small Interfering, HSF1, Protein Kinase Inhibitors, Molecular Biology, Heat-Shock Proteins, Cell Proliferation, EGFR inhibitors, biology, Hepatocyte growth factor receptor, Reverse Transcriptase Polymerase Chain Reaction, Cell Cycle, Proto-Oncogene Proteins c-met, Xenograft Model Antitumor Assays, Up-Regulation, Gene Expression Regulation, Neoplastic, Drug Resistance, Neoplasm, Hepatocyte Growth Factor Receptor, embryonic structures, Hepatocyte growth factor receptor, EGFR, Cancer research, biology.protein, Tyrosine kinase, Molecular Chaperones, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df6ce1d7c2dbc83a1537e8159af50a7Test
https://doi.org/10.1096/fj.13-247924Test