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ABC Transporters in Bacterial Nanomachineries

التفاصيل البيبلوغرافية
العنوان: ABC Transporters in Bacterial Nanomachineries
المؤلفون: Florestan L. Bilsing, Manuel T. Anlauf, Eymen Hachani, Sakshi Khosa, Lutz Schmitt
المصدر: International Journal of Molecular Sciences, Vol 24, Iss 7, p 6227 (2023)
بيانات النشر: MDPI AG, 2023.
سنة النشر: 2023
المجموعة: LCC:Biology (General)
LCC:Chemistry
مصطلحات موضوعية: ABC transporter, nanomachineries, Mac system, Lpt system, Mla system, Lol system, Biology (General), QH301-705.5, Chemistry, QD1-999
الوصف: Members of the superfamily of ABC transporters are found in all domains of life. Most of these primary active transporters act as isolated entities and export or import their substrates in an ATP-dependent manner across biological membranes. However, some ABC transporters are also part of larger protein complexes, so-called nanomachineries that catalyze the vectorial transport of their substrates. Here, we will focus on four bacterial examples of such nanomachineries: the Mac system providing drug resistance, the Lpt system catalyzing vectorial LPS transport, the Mla system responsible for phospholipid transport, and the Lol system, which is required for lipoprotein transport to the outer membrane of Gram-negative bacteria. For all four systems, we tried to summarize the existing data and provide a structure-function analysis highlighting the mechanistical aspect of the coupling of ATP hydrolysis to substrate translocation.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1422-0067
1661-6596
العلاقة: https://www.mdpi.com/1422-0067/24/7/6227Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test
DOI: 10.3390/ijms24076227
الوصول الحر: https://doaj.org/article/867591361c994a67ae73b0b133b7393aTest
رقم الانضمام: edsdoj.867591361c994a67ae73b0b133b7393a
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14220067
16616596
DOI:10.3390/ijms24076227