دورية أكاديمية
Endovascular Treatment:The Role of Dominant Caliber M2 Segment Occlusion in Ischemic Stroke
| العنوان: | Endovascular Treatment:The Role of Dominant Caliber M2 Segment Occlusion in Ischemic Stroke |
|---|---|
| المؤلفون: | Compagne, Kars C. J., van der Sluijs, Pieter M., van den Wijngaard, Ido R., Roozenbeek, Bob, Mulder, Maxim J. H. L., van Zwam, Wim H., Emmer, Bart J., Majoie, Charles B. L. M., Yoo, Albert J., Nijeholt, Geert J. Lycklama A., Lingsma, Hester F., Dippel, Diederik W. J., van der Lugt, Aad, van Es, Adriaan C. G. M., Roos, Yvo B. W. E. M., van Oostenbrugge, Robert J., Boiten, Jelis, Vos, Jan Albert, Jansen, Ivo G. H., Goldhoorn, Robert-Jan B., Schonewille, Wouter J., Coutinho, Jonathan M., Wermer, Marieke J. H., van Walderveen, Marianne A. A., Staals, Julie, Hofmeijer, Jeannette, Martens, Jasper M., de Bruijn, Sebastiaan F., van Dijk, Lukas C., van der Worp, H. Bart, Lo, Rob H., van Dijk, Ewoud J., Boogaarts, Hieronymus D., de Kort, Paul L. M., Peluso, Jo J. P., van den Berg, Jan S. P., Postma, Alida A., Groot, P. F. C. |
| المصدر: | Compagne , K C J , van der Sluijs , P M , van den Wijngaard , I R , Roozenbeek , B , Mulder , M J H L , van Zwam , W H , Emmer , B J , Majoie , C B L M , Yoo , A J , Nijeholt , G J L A , Lingsma , H F , Dippel , D W J , van der Lugt , A , van Es , A C G M , Roos , Y B W E M , van Oostenbrugge , R J .... |
| سنة النشر: | 2019 |
| المجموعة: | Maastricht University Research Publications |
| مصطلحات موضوعية: | middle cerebral artery, reperfusion, stroke, thrombectomy, treatment outcome, MIDDLE CEREBRAL-ARTERY, MECHANICAL THROMBECTOMY, ANGIOGRAPHY, OUTCOMES, SCORE, THERAPY, M1 |
| الوصف: | Background and Purpose-It is unclear whether endovascular treatment (EVT) is beneficial for patients with acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery. We aimed to compare functional outcomes, technical aspects, and complications of EVT between patients with acute ischemic stroke because of M2 and M1 occlusions in clinical practice. Furthermore, outcome and complications after EVT in dominant and nondominant caliber M2 division occlusions were studied. Methods-Data were obtained from the MR CLEAN Registry (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) which is an ongoing observational study in 16 Dutch centers performing EVT in the Netherlands. Functional outcome was measured with the modified Rankin Scale score at 90 days. Neurological recovery (delta National Institutes of Health Stroke Scale), successful reperfusion rates (extended Thrombolysis in Cerebral Infarction >= 2B), and safety outcomes were also investigated. Associations between occlusion location and outcome were analyzed with ordinal logistic regression models, with adjustment for other prognostic factors. Results-In total, 244 (24%) patients with an M2 and 759 (76%) patients with an M1 occlusion who underwent EVT were analyzed. Functional outcomes were not significantly different between patients with M2 versus M1 occlusions (adjusted common odds ratio, 1.24; 95% CI, 0.87-1.73). Occurrence of symptomatic intracerebral hemorrhage was also similar for M2 and M1 occlusions (6.6% versus 5.9%; P=0.84). Further analysis about dominance of an M2 branch was performed in 175 (72%) patients. Neurological recovery was comparable (mean delta National Institutes of Health Stroke Scale, -2 +/- 10 for dominant M2, -5 +/- 5 for nondominant M2, and -4 +/- 9 [P=0.24] for M1 occlusions). Furthermore, the effect of reperfusion status on functional outcome was comparable between occlusion divisions (common odds ratio, 1.27; 95% CI, 1.06-1.53 for dominant M2; ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1161/STROKEAHA.118.023117 |
| الإتاحة: | https://doi.org/10.1161/STROKEAHA.118.023117Test https://cris.maastrichtuniversity.nl/en/publications/bf75aee4-a236-430d-bb0e-4dfa25c0660bTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.8ED429CD |
| قاعدة البيانات: | BASE |
| DOI: | 10.1161/STROKEAHA.118.023117 |
|---|