المؤلفون: N De Bont, Thierry Lejeune, Thierry Deltombe, V Halkin, M Rahamatali, Maxime Valet, P Hanson, C Selves

المساهمون: UCL - SSS/IONS - Institute of NeuroScience, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - (MGD) Service de médecine physique et revalidation, UCL - (SLuc) Service de médecine physique et de réadaptation motrice

المصدر: Acta neurologica Belgica, Vol. 121, no. 1, p. 181-189 (2021)

مصطلحات موضوعية: Male, medicine.medical_specialty, Neurology, Activities of daily living, Population, Walk Test, Fatigability, 03 medical and health sciences, 0302 clinical medicine, Quality of life, medicine, Humans, 030212 general & internal medicine, education, Stroke, Chronic stroke, Fatigue, Depression (differential diagnoses), Aged, education.field_of_study, Depression, business.industry, General Medicine, Middle Aged, medicine.disease, Cross-Sectional Studies, Chronic Disease, Physical therapy, Anxiety, Female, Perception, Self Report, Neurology (clinical), medicine.symptom, business, Psychomotor Performance, 030217 neurology & neurosurgery

الوصف: Post-stroke fatigue (PSF) is a common symptom associated with disability and decreased quality of life. Distinction can be made between perceived fatigue and fatigability. The first aim of this study was to evaluate the prevalence of perceived fatigue and fatigability amongst patients with chronic stroke and to explore how these two parameters relate. The second aim was to study the relationship between modifiable factors (sleep disorders, anxiety, depression and activities of daily living) and fatigue in this population. Sixty-two patients with chronic stroke (> 6 months) were included. Perceived fatigue was evaluated using the Fatigue Severity Scale (FSS). Motor fatigability was assessed with the percent change in meters walked from first to last minute of the 6-min Walk Test and an isometric muscular fatigability test. Subjects also completed self-report questionnaires assessing anxiety and depression (Hospital Anxiety and Depression Scale-HADS), sleep quality (Pittsburgh Sleep Quality Index-PSQI) and activity limitations (ACTIVLIM-stroke). Seventy-one percent of participants presented PSF. There was no correlation between the FSS and motor fatigability. FSS significantly correlated with HADS-Anxiety (ρ = 0.53, P

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce02be6829a6189e07b04b76d3a0bebTest
https://doi.org/10.1007/s13760-020-01453-9Test

المؤلفون: Maxime Valet, Gaëtan Stoquart, Marc Francaux, Clémence de Broglie, Thierry Lejeune

المصدر: Scandinavian Journal of Medicine & Science in Sports. 30:1908-1917

مصطلحات موضوعية: Adult, Data Analysis, Male, medicine.medical_specialty, Multiple Sclerosis, Physical fitness, Physical Therapy, Sports Therapy and Rehabilitation, 030204 cardiovascular system & hematology, Work rate, 03 medical and health sciences, Oxygen Consumption, 0302 clinical medicine, Heart Rate, Internal medicine, Heart rate, Humans, Medicine, Orthopedics and Sports Medicine, Respiratory exchange ratio, Retrospective Studies, Exercise Tolerance, Pulmonary Gas Exchange, business.industry, Case-control study, VO2 max, Cardiorespiratory fitness, 030229 sport sciences, Middle Aged, Standard error, Case-Control Studies, Cardiology, Female, business, human activities

الوصف: Among patients with multiple sclerosis (MS), the impairment of exercise tolerance is closely related to disability. Maximal oxygen uptake (VO2max ) is the gold standard to assess exercise tolerance in healthy subjects (HS). Among patients with MS, the accuracy of VO2max measurement is often impaired because the patients are unable to reach the maximal exercise intensity due to interdependent factors linked to the disease (such as pathological fatigue, pain, lack of exercise habit, and lack of mobility). This study assesses the accuracy of simplified indices for assessing exercise tolerance, which are more suitable in patients with MS. They are simple in the way they are either measurable during submaximal exercise (oxygen uptake efficiency slopes (OUES), physical working capacity at 75% of maximal heart rate (PWC75% ), oxygen consumption at a respiratory exchange ratio of 1 (VO2 @RER1)) or not based on gas exchange analysis (peak work rate (PWR)-based predictive equation and PWC75% ). All indices were significantly lower in the MS group compared to the HS group (P .70, P < .001) with VO2peak , in both groups, without difference between groups. PWR-based prediction of VO2peak showed a standard error of the estimate of 315 mL min-1 in HS and 176 mL min-1 in MS. PWC75% did not correlate to VO2peak in neither group. These findings suggest an impairment of exercise tolerance functions in mildly disabled persons with MS, independently from other factors. Submaximal indices involving gas exchange analysis or peakWR-based estimation of VO2peak are usable to accurately assess exercise tolerance.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888c232705c5aa92a1b98a3745f88327Test
https://doi.org/10.1111/sms.13756Test

المؤلفون: Vincent Van Pesch, Gaëtan Stoquart, Souraya El Sankari, Thierry Lejeune, Christine Detrembleur, Maxime Valet

المساهمون: UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - (SLuc) Service de médecine physique et de réadaptation motrice, UCL - (SLuc) Service de neurologie

المصدر: Clinical Biomechanics, Vol. 86, no.-, p. 105382 (2021)

مصطلحات موضوعية: Adult, medicine.medical_specialty, Multiple Sclerosis, Placebo-controlled study, Biophysics, Walking, law.invention, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Randomized controlled trial, law, Potassium Channel Blockers, Medicine, Humans, Orthopedics and Sports Medicine, Treadmill, 4-Aminopyridine, Gait, Expanded Disability Status Scale, business.industry, Repeated measures design, 030229 sport sciences, Middle Aged, Preferred walking speed, Treatment Outcome, Gait analysis, Female, business, human activities, 030217 neurology & neurosurgery

الوصف: Background People with multiple sclerosis have reduced walking speed and impaired gait pattern. Prolonged release-fampridine is a potassium channel blocker that improves nerve conduction in patients with multiple sclerosis, leading to walking benefits. Whether fampridine alters gait pattern is unknown. Methods In this crossover, randomized controlled trial, patients with multiple sclerosis were tested for responder status during a 4-week run-in period. Patients were considered responders if they improved their 25-ft walk test by 10% and improved their perceived walking capacity. Responders were randomized to prolonged release-fampridine (10 mg b.i.d.) or placebo for a 6-week period. After a 2-week wash-out period, they were allocated to the other treatment for 6 weeks. Participants were assessed before and after both conditions. Three-dimensional gait analysis assessed kinematic, kinetic, mechanic and energetic variables while walking on a treadmill at comfortable speed. Six-minute walk test and 25-ft walk test were used to assess walking speed on middle and short-distances, respectively. Patient-reported outcome measures were also used. Repeated measures ANCOVAs were applied to assess the treatment effects. Findings Out of 39 included patients, 24 responders (12 women; Expanded Disability Status Scale:4.25[4–5]; age:46 ± 10 years; maximal speed:0.93 ± 0.38 m·s−1) were identified. Among them, prolonged release-fampridine reduced the external mechanical work (−0.039 J·kg−1·m−1;p = 0.02), and improved knee flexion during swing phase (+5.3°; p = 0.02). No differences were found in other walking tests and patient-reported outcomes, at group-level. Interpretation Prolonged release-fampridine increases knee flexion during swing phase and lowers mechanical external work. Whether these changes are related to clinically meaningful improvements in walking capacity and other functional variables should be further investigated.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaa9ad273bcded7531186897d356bbfTest
https://hdl.handle.net/2078.1/246184Test

المؤلفون: Thierry Lejeune, Vincent Van Pesch, Maxime Valet, Gaëtan Stoquart, Alice De Haan, Caroline Remy, Souraya El Sankari

المساهمون: UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service de médecine physique et de réadaptation motrice, UCL - (SLuc) Service de neurologie

المصدر: European journal of physical and rehabilitation medicine, Vol. 56, no. 4, p. 403-411 (2020)

مصطلحات موضوعية: Adult, Male, 030506 rehabilitation, Multiple Sclerosis, Cross-sectional study, medicine.medical_treatment, Population, Psychological intervention, MEDLINE, Physical Therapy, Sports Therapy and Rehabilitation, Logistic regression, Health Services Accessibility, 03 medical and health sciences, 0302 clinical medicine, Telerehabilitation, Medicine, Humans, education, education.field_of_study, Rehabilitation, Descriptive statistics, business.industry, Middle Aged, Patient Acceptance of Health Care, Cross-Sectional Studies, Female, 0305 other medical science, business, Telecommunications, 030217 neurology & neurosurgery

الوصف: Background Telerehabilitation is a promising approach for patients with multiple sclerosis (MS), but uncertainties regarding patients' access and preferences remain. Aim To investigate the access to telecommunication technologies and rehabilitation services of patients with MS, and their willingness to use these technologies for rehabilitation. Design Cross-sectional survey. Setting Outpatient neurological facility. Population Patients with MS. Methods Patients with MS attending consultations in the Neurology department were asked to fill in a paper questionnaire. This anonymous questionnaire was designed to gain information about needs and access to rehabilitation and telecommunication technologies, as well as interests and perspectives of telerehabilitation among these patients. Descriptive statistics, chi- squared tests and logistic regressions were used to describe the sample and survey answers. Results Two hundred patients completed the questionnaire. Mean age was 44.41(±12.52) years. Seventy-one percent were women, and 49% were unemployed. Ninety-one percent of the patients regularly used internet and 73% used apps. Most patients were interested in using telecommunication technologies to receive a program of physical exercises (62%), for information and personalized advice about physical activity and MS (69%), and to communicate with caregivers (75%). Patients with EDSS>4 were less interested than patients with EDSS≤4 in communicating with the caregivers via apps (33%vs52%,Δ19%[CI-36%;- 2%],p=0.04) but expressed greater interest in receiving information and personal advice about physical activity and MS via the internet (70%vs51%,Δ19%[CI+2%;+36%],p=0.03). One third of the patients was not interested in receiving telerehabilitation interventions (32%), notably patients with EDSS>4 and non-workers. Conclusions Patients with MS are mainly interested in using telecommunication technologies for rehabilitation services, and most of these patients have access to the required technology. Being mildly disabled and having a professional activity are associated with a greater interest in telerehabilitation. In contrary, patients with moderate-to-severe disability and non-workers have reportedly less access and ease in using the required technologies. Clinical rehabilitation impact Telerehabilitation is feasible and wished by patients with MS, specifically in patients with low EDSS scores and workers. Given the strong need for rehabilitation in more disabled patients, the barriers to its access, the lower access and ease of use of telecommunication technologies, a special effort is needed to facilitate their use in these patients.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b364bfdf0e9cb8959501a36383c363Test
https://pubmed.ncbi.nlm.nih.gov/32293811Test

المؤلفون: Thierry Lejeune, Svetlana Khatkova, Lynne Turner-Stokes, Philippe Picaut, Pascal Maisonobe, Jovita Balcaitiene, François Constant Boyer

المساهمون: UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - (SLuc) Service de médecine physique et de réadaptation motrice

المصدر: Journal of rehabilitation medicine, Vol. 52, no. 6, p. jrm00068 [1-9] (2020)
Journal of Rehabilitation Medicine, Vol 52, Iss 6, p jrm00068 (2020)

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, Shoulder, shoulder pain, Acetylcholine Release Inhibitors, Physical Therapy, Sports Therapy and Rehabilitation, RM1-950, Injections, abobotulinumtoxinA, Humans, Botulinum Toxins, Type A, muscle spasticity, shoulder joint, clinical trials, Rehabilitation, General Medicine, Middle Aged, phase III, abobotulinumtoxina, Treatment Outcome, clinical trials, phase iii, Neuromuscular Agents, Muscle Spasticity, Female, observational study, Therapeutics. Pharmacology, human activities

الوصف: Botulinum toxins, such as abobotulinumtoxinA, are used to treat spasticity (muscle overactivity) in arm muscles. Spasticity in shoulder muscles occurs in many patients following a stroke. Shoulder spasticity can be painful and limit limb movement. This paper compares the results from patients who did and those who did not receive abobotulinumtoxinA injections in shoulder muscles (among other arm muscles) in 2 studies. In both studies, the results showed that more patients receiving treatment in shoulder muscles chose pain as a key goal for treatment and had reduced pain following treatment compared with patients not treated in the shoulder. In addition, patients receiving shoulder injections showed further improvement in arm movement compared with those not receiving shoulder injections. Overall, these results suggest that abobotulinumtoxinA treatment in shoulder muscles may improve outcomes for patients with arm spasticity involving the shoulder.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71feaf2e77ac620ce24b386372f1dda3Test
https://hdl.handle.net/2078.1/230235Test

المؤلفون: Thierry Lejeune, Martin Edwards, Stéphanie Dehem, Vincenza Montedoro, Marie Alsamour, Bruno Dehez

المساهمون: UCL - SSH/IPSY - Psychological Sciences Research Institute, UCL - SST/IMMC - Institute of Mechanics, Materials and Civil Engineering, UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - (SLuc) Service de médecine physique et de réadaptation motrice

المصدر: Archives of Clinical Neuropsychology

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Future studies, Intraclass correlation, media_common.quotation_subject, Standardized test, Neuropsychological Tests, Sensitivity and Specificity, Functional Laterality, 050105 experimental psychology, Neglect, Perceptual Disorders, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Reference Values, medicine, Humans, Attention, 0501 psychology and cognitive sciences, Diagnosis, Computer-Assisted, Reliability (statistics), Aged, media_common, Aged, 80 and over, business.industry, 05 social sciences, Reproducibility of Results, Robotics, General Medicine, Middle Aged, Test (assessment), Stroke, Psychiatry and Mental health, Clinical Psychology, Neuropsychology and Physiological Psychology, Unilateral neglect, Case-Control Studies, Space Perception, Clinical diagnosis, Female, business, Psychology, 030217 neurology & neurosurgery

الوصف: OBJECTIVE Patients with hemineglect fail to respond to egocentric stimuli or allocentric parts of stimuli contralateral to the brain lesion. The clinical diagnosis of hemineglect mainly involves evaluation of the egocentric form, while less sensitive standardized tests exist for other forms. Our global aim is to develop an innovative integrative robot measure, the MonAmour test, combining the assessment of egocentric, allocentric and motor hemineglect. Here, we present the egocentric and allocentric evaluations. METHODS Thirty-five first stroke patients (25 hemineglect) and 56 age-matched healthy controls were assessed on the index test (MonAmour) and on three reference standard tests (Bells test, Apples test and Neglect subtest of the Test for Attentional Performance). Based on controls' performance, normative data were created. Validity was evaluated between the MonAmour and the reference standard tests through correlations and test sensitivity/specificity. Reliability of the MonAmour was measured with test-retest and minimal detectable change. RESULTS Results demonstrated moderate to strong correlations between the MonAmour and the reference standard tests (r = .40-.88, p < .001 - p = .016). The sensitivity was high (50%-96%), with accurate diagnosis of patients with hemineglect, and reliability was excellent (Intraclass Correlation Coefficient = .79-.95, p < .001). CONCLUSIONS The MonAmour robot test is a valid, sensitive and reliable tool that can diagnose egocentric and allocentric hemineglect. Future studies will deepen the assessment and understanding of the different forms of hemineglect by testing the motor component of the test in order to use this accurate and integrative measure in daily clinical routine. REGISTRATION ClinicalTrials.gov(NCT02543424).

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90a2d3d498c4d525cd36fc2b9a82be8Test
https://doi.org/10.1093/arclin/acy062Test

المؤلفون: Gaëtan Stoquart, Maxime Gilliaux, Christine Detrembleur, Stéphanie Dehem, Julien Sapin, Thierry Lejeune, Daniel Galinski, Martin Vanderwegen

المساهمون: UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - (SLuc) Service de médecine physique et de réadaptation motrice, UCL - SST/IMMC/MEED - Mechatronic, Electrical Energy, and Dynamics Systems

المصدر: Journal of Rehabilitation Medicine, Vol. 49, no.49, p. 565–571 (2017)
Journal of Rehabilitation Medicine, Vol 49, Iss 7, Pp 565-571 (2017)

مصطلحات موضوعية: Male, 0209 industrial biotechnology, medicine.medical_specialty, Stroke patient, Elbow flexor, Motor nerve, Physical Therapy, Sports Therapy and Rehabilitation, RM1-950, 02 engineering and technology, upperextremity, 03 medical and health sciences, 020901 industrial engineering & automation, 0302 clinical medicine, Physical medicine and rehabilitation, Robotic Surgical Procedures, Humans, Medicine, Resistance force, Spasticity, Chronic stroke, business.industry, Rehabilitation, Stroke Rehabilitation, Robotics, General Medicine, Middle Aged, Stroke, body regions, medicine.anatomical_structure, Muscle Spasticity, Chronic Disease, Upper limb, Female, Therapeutics. Pharmacology, Upper limb spasticity, medicine.symptom, business, robotics,musclespasticity, 030217 neurology & neurosurgery, symptomassessment

الوصف: Objective: To assess the capacity of the robotic device REAplan to measure overall upper limb peak resistance force, as a reflection of upper limb spasticity. Methods: Twelve patients with chronic stroke presenting upper limb spasticity were recruited to the study. Patients underwent musculocutaneous motor nerve block to reduce the spasticity of elbow flexor muscles. Each patient was assessed before and after the motor nerve block. Overall the REAplan measured upper limb resistance force. The robot passively mobilized the patient’s upper limb at various velocities (10, 20, 30, 40 and 50 cm/s) in a back-and-forth trajectory (30 cm). The peak resistance force was analysed for each forward movement. Ten movements were performed and averaged at each velocity condition. Results: The overall upper limb resistance force increased proportionally to the mobilization velocity (p < 0.001). Resistance force decreased after the motor nerve block at 40 and 50 cm/s (p < 0.05). Overall upper limb resistance force results showed excellent correlation with the Modified Ashworth Scale for elbow flexor muscles, for each velocity condition equal or higher than 30 cm/s (ρ >0.6). Conclusion: This study proposes a new, valid, reliable and sensitive protocol to quantify upper limb resistance force using the REAplan, as a reflection of upper limb spasticity.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e9fdfbd2ccafb006fe973d3f878666Test
https://doi.org/10.2340/16501977-2248Test

المؤلفون: Charles Sèbiyo Batcho, Etienne Alagnide, Toussaint G. Kpadonou, Ditouah Didier Niama Natta, Gaëtan Stoquart, Thierry Lejeune

المساهمون: UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - (SLuc) Service de médecine physique et de réadaptation motrice

المصدر: European journal of physical and rehabilitation medicine, Vol. 55, no. 1, p. 19-28 (2019)

مصطلحات موضوعية: Adult, Male, 030506 rehabilitation, medicine.medical_specialty, Activities of daily living, Population, Physical Therapy, Sports Therapy and Rehabilitation, Disability Evaluation, 03 medical and health sciences, 0302 clinical medicine, Surveys and Questionnaires, Activities of Daily Living, Benin, Humans, Medicine, education, Aged, education.field_of_study, Rasch model, business.industry, Rehabilitation, Reproducibility of Results, Construct validity, Polytomous Rasch model, Middle Aged, Hand, Functional Independence Measure, Differential item functioning, Stroke, Cross-Sectional Studies, Motor Skills, Physical therapy, Female, Observational study, 0305 other medical science, business, 030217 neurology & neurosurgery

الوصف: Background ABILHAND is a self-reported questionnaire assessing manual ability. It was validated and calibrated using the Rasch analysis for European stroke patients. After a stroke, performing upper limb activities of daily living is influenced by personal and environmental contextual factors. It is thus important to conduct a contextual validation to use this questionnaire outside of Europe. Aim The aim of this study was to perform a cross cultural validation of the ABILHAND-Stroke questionnaire for post-stroke patients living in Benin, a West-African country. Design Observational cross-sectional study. Setting Outpatient rehabilitation centres. Population 223 Beninese chronic stroke patients. Methods The experimental questionnaire was made of 59 items evaluating manual activities. Patients had to estimate their difficulty of performing each activity according to four response categories: impossible, very difficult, difficult and easy. For construct validity analysis, patients were also evaluated with other assessment tools: Box and Block Test, the motor subscale of the Functional Independence Measure, the Stroke Impairment Assessment Set, and ACTIVLIM-Stroke. Data were analysed with the Rasch partial credit model. Results The response categories very difficult and difficult were merged and the number of response categories was reduced from 4 to 3 (impossible, difficult and easy). The Rasch analyses selected 16 bimanual activities that fit the Rasch model (chi square=42.35; P=0.10). The item location ranged from -1.10 to 2.24 logits. The standard error ranged from 0.15 to 0.22 logits. There is no differential item functioning between subgroups (age, sex, dexterity, affected side, time since stroke). The person separation index is 0.82. The questionnaire can measure 3 levels of manual ability, similarly to the occidental version. Conclusions The ABILHAND-stroke is a Rasch validated, unidimensional and invariant questionnaire to assess manual ability among Beninese patients. The ordinal score can be transformed into linear score using a conversion table. Clinical rehabilitation impact This assessment tool is clinically relevant in Benin, a developing country, since it requires no specific equipment or training. It should promote and standardize assessments for stroke patients in clinical practice and research in this African country.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a0c84f39f53205b6f7dfec1fb392e4Test
https://doi.org/10.23736/s1973-9087.18.05195-xTest

المؤلفون: Sophie Heins, Dehez Bruno, Martin Edwards, Stéphanie Dehem, Christine Detrembleur, Thierry Lejeune, Vincenza Montedoro, Gaëtan Stoquart, Anne Renders

المساهمون: UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - SSH/IPSY - Psychological Sciences Research Institute, UCL - (SLuc) Service de médecine physique et de réadaptation motrice, UCL - SST/IMMC/MEED - Mechatronic, Electrical Energy, and Dynamics Systems

المصدر: NeuroRehabilitation, Vol. 44, no.2, p. 263-274 (2019)

مصطلحات موضوعية: Adult, Male, 030506 rehabilitation, medicine.medical_specialty, Stroke patient, Physical Therapy, Clinical Neurology, Physical Therapy, Sports Therapy and Rehabilitation, Isometric exercise, Kinematics, Serious game, Sports Therapy and Rehabilitation, Upper Extremity, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, medicine, Humans, Muscle Strength, Motor assessment, Aged, business.industry, Rehabilitation, Stroke Rehabilitation, Healthy subjects, Robotics, Middle Aged, Biomechanical Phenomena, medicine.anatomical_structure, Motor Skills, Upper limb, Female, Neurology (clinical), Artificial intelligence, 0305 other medical science, business, human activities, 030217 neurology & neurosurgery

الوصف: BACKGROUND: ROBiGAME project aims to implement serious games on robots to rehabilitate upper limb (UL) in stroke patients. The serious game characteristics (target position, level of assistance/resistance, level of force) are adapted based on the patient’s assessment before and continuously during the game (measuring UL working area, kinematics and muscle strength). OBJECTIVE: To develop an UL robotic motor assessment protocol to configure the serious game. METHODS: 32 healthy subjects and 20 stroke patients participated in the study. Subjects were clinically assessed (UL length and isometric force) and using a robot. The robot assessment consisted of the patient’s UL working area (WA), the UL isometric and isokinetic force in three directions and the UL kinematics during a pointing task toward targets placed at different distances. RESULTS: The WA and the UL isometric force were moderately to highly correlated with clinical measures (respectively ρ = 0.52; p = 0.003, ρ = 0.68–0.73; p < 0.001). Ratios between the UL isokinetic force generated on three directions were established. The velocity and straightness indexes of all subjects increased when subjects had to reach to targets placed more distantly (r = 0.82–0.90; ρ = 0.86–0.90 respectively; p < 0.001). AUTHOR COPY CONCLUSIONS: This protocol can be integrated into a serious game in order to continuously configure the game charac- teristics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baca10d671aaeb7e4f7f75fbe6419a5fTest

المؤلفون: Gaëtan Stoquart, Géraldine Jacquemin, Christine Detrembleur, Thierry Lejeune, Maxime Gilliaux, Stéphanie Dehem, Sara Palumbo, Anne Frederick

المساهمون: UCL - SSS/IREC/NMSK - Neuro-musculo-skeletal Lab, UCL - (SLuc) Service de médecine physique et de réadaptation motrice

المصدر: Annals of Physical and Rehabilitation Medicine, Vol. 62, no. 5, p. 313-320 (2019)

مصطلحات موضوعية: Male, 030506 rehabilitation, medicine.medical_specialty, Activities of daily living, medicine.medical_treatment, Psychological intervention, Phase (combat), rehabilitation, law.invention, Upper Extremity, 03 medical and health sciences, Disability Evaluation, 0302 clinical medicine, Physical medicine and rehabilitation, Randomized controlled trial, International Classification of Functioning, Disability and Health, law, upper extremity, medicine, Humans, Orthopedics and Sports Medicine, Single-Blind Method, Stroke, Aged, robotics, Rehabilitation, business.industry, Recovery of function, Stroke Rehabilitation, Recovery of Function, Robotics, Middle Aged, medicine.disease, stroke, Exercise Therapy, Paresis, medicine.anatomical_structure, Treatment Outcome, Upper limb, Female, 0305 other medical science, business, 030217 neurology & neurosurgery

الوصف: Background Upper-limb robotic-assisted therapy (RAT) is promising for stroke rehabilitation, particularly in the early phase. When RAT is provided as partial substitution of conventional therapy, it is expected to be at least as effective or might be more effective than conventional therapy. Assessments have usually been restricted to the first 2 domains of the International classification of functioning, disability and health (ICF). Objective This was a pragmatic, multicentric, single-blind, randomized controlled trial to evaluate the effectiveness of upper-limb RAT used as partial substitution to conventional therapy in the early phase of stroke rehabilitation, following the 3 ICF domains. Methods We randomized 45 patients with acute stroke into 2 groups (conventional therapy, n = 22, and RAT, n = 23). Both interventions were dose-matched regarding treatment duration and lasted 9 weeks. The conventional therapy group followed a standard rehabilitation. In the RAT group, 4 sessions of conventional therapy (25%) were substituted by RAT each week. RAT consisted of moving the paretic upper limb along a reference trajectory while the robot provided assistance as needed. A blinded assessor evaluated participants before, just after the intervention and 6 months post-stroke, according to the ICF domains UL motor impairments, activity limitations, and social participation restriction. Results In total, 28 individuals were assessed after the intervention. The following were more improved in the RAT than conventional therapy group at 6 months post-stroke: gross manual dexterity (Box and Block test +7.7 blocks; P = 0.02), upper-limb ability during functional tasks (Wolf Motor Function test +12%; P = 0.02) and patient social participation (Stroke Impact Scale +18%; P = 0.01). Participants’ abilities to perform manual activities and activities of daily living improved similarly in both groups. Conclusion For the same duration of daily rehabilitation, RAT combined with conventional therapy during the early rehabilitation phase after stroke is more effective than conventional therapy alone to improve gross manual dexterity, upper-limb ability during functional tasks and patient social participation.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b331a3fc6e1fa1c845ea833d80df24Test
https://pubmed.ncbi.nlm.nih.gov/31028900Test