دورية أكاديمية
Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study. A WSES observational study
| العنوان: | Physiological parameters for Prognosis in Abdominal Sepsis (PIPAS) Study. A WSES observational study |
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| المؤلفون: | Sartelli, Massimo, Abu-Zidan, Fikri M, Labricciosa, Francesco M, Kluger, Yoram, Coccolini, Federico, Ansaloni, Luca, Leppäniemi, Ari, Kirkpatrick, Andrew W, Tolonen, Matti, Tranà, Cristian, Regimbeau, Jean-Marc, Hardcastle, Timothy, Koshy, Renol M, Abbas, Ashraf, Aday, Ulaş, Adesunkanmi, A R K, Ajibade, Adesina, Akhmeteli, Lali, Akın, Emrah, Akkapulu, Nezih, Alotaibi, Alhenouf, Altintoprak, Fatih, Anyfantakis, Dimitrios, Atanasov, Boyko, Augustin, Goran, Azevedo, Constança, Bala, Miklosh, Balalis, Dimitrios, Baraket, Oussama, Baral, Suman, Barkai, Or, Beltran, Marcelo, Bini, Roberto, Bouliaris, Konstantinos, Caballero, Ana B, Calu, Valentin, Catani, Marco, Ceresoli, Marco, Charalampakis, Vasileios, Jusoh, Asri Che, Chiarugi, Massimo, Cillara, Nicola, Cuesta, Raquel Cobos, Cobuccio, Luigi, Cocorullo, Gianfranco, Colak, Elif, Conti, Luigi, Cui, Yunfeng, De Simone, Belinda, Delibegovic, Samir, Demetrashvili, Zaza, Demetriades, Demetrios, Dimova, Ana, Dogjani, Agron, Enani, Mushira, Farina, Federica, Ferrara, Francesco, Foghetti, Domitilla, Fontana, Tommaso, Fraga, Gustavo P, Gachabayov, Mahir, Gérard, Grelpois, Ghnnam, Wagih, Maurel, Teresa Giménez, Gkiokas, Georgios, Gomes, Carlos A, Guner, Ali, Gupta, Sanjay, Hecker, Andreas, Hirano, Elcio S, Hodonou, Adrien, Hutan, Martin, Ilaschuk, Igor, Ioannidis, Orestis, Isik, Arda, Ivakhov, Georgy, Jain, Sumita, Jokubauskas, Mantas, Karamarkovic, Aleksandar, Kaushik, Robin, Kenig, Jakub, Khokha, Vladimir, Khokha, Denis, Kim, Jae Il, Kong, Victor, Korkolis, Dimitris, Kruger, Vitor F, Kshirsagar, Ashok, Simões, Romeo Lages, Lanaia, Andrea, Lasithiotakis, Konstantinos, Leão, Pedro, Arellano, Miguel León, Listle, Holger, Litvin, Andrey, Lizarazu Pérez, Aintzane, Lopez-Tomassetti Fernandez, Eudaldo, Lostoridis, Eftychios, Luppi, Davide, Machain V, Gustavo M, Major, Piotr, Manatakis, Dimitrios, Reitz, Marianne Marchini, Marinis, Athanasios, Marrelli, Daniele, Martínez-Pérez, Aleix, Marwah, Sanjay, McFarlane, Michael, Mesic, Mirza, Mesina, Cristian, Michalopoulos, Nickos, Misiakos, Evangelos, Moreira, Felipe Gonçalves, Mouaqit, Ouadii, Muhtaroglu, Ali, Naidoo, Noel, Negoi, Ionut, Nikitina, Zane, Nikolopoulos, Ioannis, Nita, Gabriela-Elisa, Occhionorelli, Savino, Olaoye, Iyiade, Ordoñez, Carlos A, Ozkan, Zeynep, Pal, Ajay, Palini, Gian M, Papageorgiou, Kyriaki, Papagoras, Dimitris, Pata, Francesco, Pędziwiatr, Michał, Pereira, Jorge, Pereira Junior, Gerson A, Perrone, Gennaro, Pintar, Tadeja, Pisarska, Magdalena, Plehutsa, Oleksandr, Podda, Mauro, Poillucci, Gaetano, Quiodettis, Martha, Rahim, Tuba, Rios-Cruz, Daniel, Rodrigues, Gabriel, Rozov, Dmytry, Sakakushev, Boris, Sall, Ibrahima, Sazhin, Alexander, Semião, Miguel, Sharda, Taanya, Shelat, Vishal, Sinibaldi, Giovanni, Skicko, Dmitrijs, Skrovina, Matej, Stamatiou, Dimitrios, Stella, Marco, Strzałka, Marcin, Sydorchuk, Ruslan, Teixeira Gonsaga, Ricardo A, Tochie, Joel Noutakdie, Tomadze, Gia, Ugoletti, Lara, Ulrych, Jan, Ümarik, Toomas, Uzunoglu, Mustafa Y, Vasilescu, Alin, Vaz, Osborne, Vereczkei, Andras, Vlad, Nutu, Walędziak, Maciej, Yahya, Ali I, Yalkin, Omer, Yilmaz, Tonguç U, Ünal, Ali Ekrem, Yuan, Kuo-Ching, Zachariah, Sanoop K, Žilinskas, Justas, Zizzo, Maurizio, Pattonieri, Vittoria, Baiocchi, Gian Luca, Catena, Fausto |
| المساهمون: | Sartelli, Massimo, Abu-Zidan, Fikri M, Labricciosa, Francesco M, Kluger, Yoram, Coccolini, Federico, Ansaloni, Luca, Leppäniemi, Ari, Kirkpatrick, Andrew W, Tolonen, Matti, Tranà, Cristian, Regimbeau, Jean-Marc, Hardcastle, Timothy, Koshy, Renol M, Abbas, Ashraf, Aday, Ulaş, Adesunkanmi, A R K, Ajibade, Adesina, Akhmeteli, Lali, Akın, Emrah, Akkapulu, Nezih, Alotaibi, Alhenouf, Altintoprak, Fatih, Anyfantakis, Dimitrio, Atanasov, Boyko, Augustin, Goran, Azevedo, Constança, Bala, Miklosh, Balalis, Dimitrio, Baraket, Oussama, Baral, Suman, Barkai, Or, Beltran, Marcelo, Bini, Roberto, Bouliaris, Konstantino, Caballero, Ana B, Calu, Valentin, Catani, Marco, Ceresoli, Marco, Charalampakis, Vasileio, Jusoh, Asri Che, Chiarugi, Massimo, Cillara, Nicola, Cuesta, Raquel Cobo, Cobuccio, Luigi, Cocorullo, Gianfranco, Colak, Elif, Conti, Luigi, Cui, Yunfeng, De Simone, Belinda, Delibegovic, Samir, Demetrashvili, Zaza, Demetriades, Demetrio, Dimova, Ana, Dogjani, Agron, Enani, Mushira, Farina, Federica, Ferrara, Francesco, Foghetti, Domitilla, Fontana, Tommaso, Fraga, Gustavo P, Gachabayov, Mahir, Gérard, Grelpoi, Ghnnam, Wagih, Maurel, Teresa Giménez, Gkiokas, Georgio, Gomes, Carlos A, Guner, Ali, Gupta, Sanjay, Hecker, Andrea, Hirano, Elcio S, Hodonou, Adrien, Hutan, Martin, Ilaschuk, Igor, Ioannidis, Oresti, Isik, Arda, Ivakhov, Georgy, Jain, Sumita, Jokubauskas, Manta, Karamarkovic, Aleksandar, Kaushik, Robin, Kenig, Jakub, Khokha, Vladimir, Khokha, Deni, Kim, Jae Il, Kong, Victor, Korkolis, Dimitri, Kruger, Vitor F, Kshirsagar, Ashok, Simões, Romeo Lage, Lanaia, Andrea, Lasithiotakis, Konstantino, Leão, Pedro, Arellano, Miguel León, Listle, Holger, Litvin, Andrey, Lizarazu Pérez, Aintzane, Lopez-Tomassetti Fernandez, Eudaldo, Lostoridis, Eftychio, Luppi, Davide, Machain V, Gustavo M |
| بيانات النشر: | Springer Nature CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND |
| سنة النشر: | 2019 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | acute peritoniti, aarly warning score, emergency surgery, source control, abdomen, adult, aged, chi-square distribution, female, hospital mortality, human, injury severity score, logistic model, male, middle aged, risk factor, sepsi, prognosis |
| الوصف: | Background: Timing and adequacy of peritoneal source control are the most important pillars in the management of patients with acute peritonitis. Therefore, early prognostic evaluation of acute peritonitis is paramount to assess the severity and establish a prompt and appropriate treatment. The objectives of this study were to identify clinical and laboratory predictors for in-hospital mortality in patients with acute peritonitis and to develop a warning score system, based on easily recognizable and assessable variables, globally accepted. Methods: This worldwide multicentre observational study included 153 surgical departments across 56 countries over a 4-month study period between February 1, 2018, and May 31, 2018. Results: A total of 3137 patients were included, with 1815 (57.9%) men and 1322 (42.1%) women, with a median age of 47years (interquartile range [IQR] 28-66). The overall in-hospital mortality rate was 8.9%, with a median length of stay of 6days (IQR 4-10). Using multivariable logistic regression, independent variables associated with in-hospital mortality were identified: age > 80years, malignancy, severe cardiovascular disease, severe chronic kidney disease, respiratory rate >= 22 breaths/min, systolic blood pressure < 100mmHg, AVPU responsiveness scale (voice and unresponsive), blood oxygen saturation level (SpO(2)) < 90% in air, platelet count < 50,000 cells/mm3, and lactate > 4mmol/l. These variables were used to create the PIPAS Severity Score, a bedside early warning score for patients with acute peritonitis. The overall mortality was 2.9% for patients who had scores of 0-1, 22.7% for those who had scores of 2-3, 46.8% for those who had scores of 4-5, and 86.7% for those who have scores of 7-8. Conclusions: The simple PIPAS Severity Score can be used on a global level and can help clinicians to identify patients at high risk for treatment failure and mortality. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/31341511; info:eu-repo/semantics/altIdentifier/wos/WOS:000475741400001; volume:14; numberofpages:11; journal:WORLD JOURNAL OF EMERGENCY SURGERY; https://hdl.handle.net/11573/1659858Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85069147924 |
| DOI: | 10.1186/s13017-019-0253-2 |
| الإتاحة: | https://doi.org/10.1186/s13017-019-0253-2Test https://hdl.handle.net/11573/1659858Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.DC82CD08 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13017-019-0253-2 |
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