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المؤلفون: Michela Verzè, Elisa Giovannetti, Alessandro Leonetti, Amir Avan, Roberta Minari, Alessandro Gregori, Mjriam Capula, Filippo Papini, Paola Bordi, Giulia Mazzaschi, Btissame El Hassouni, Marcello Tiseo
المساهمون: Medical oncology laboratory, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, Amsterdam Gastroenterology Endocrinology Metabolism
المصدر: Cells, 10(6):1520. MDPI Multidisciplinary Digital Publishing Institute
Leonetti, A, Capula, M, Minari, R, Mazzaschi, G, Gregori, A, el Hassouni, B, Papini, F, Bordi, P, Verzè, M, Avan, A, Tiseo, M & Giovannetti, E 2021, ' Dynamic Evaluation of Circulating miRNA Profile in EGFR-Mutated NSCLC Patients Treated with EGFR-TKIs ', Cells, vol. 10, no. 6, 1520 . https://doi.org/10.3390/cells10061520Test
Cells
Cells, Vol 10, Iss 1520, p 1520 (2021)
Volume 10
Issue 6مصطلحات موضوعية: Oncology, Circulating mirnas, Male, Lung Neoplasms, medicine.medical_treatment, Drug Resistance, Disease, Targeted therapy, Basal (phylogenetics), EGFR‐mutated NSCLC, Carcinoma, Non-Small-Cell Lung, Medicine, Biology (General), Non-Small-Cell Lung, Tumor, Gefitinib, General Medicine, Middle Aged, targeted therapy, Response to EGFR‐TKI, response to EGFR-TKI, ErbB Receptors, Female, EGFR-mutated NSCLC, Adult, medicine.medical_specialty, QH301-705.5, Antineoplastic Agents, Afatinib, Article, Erlotinib Hydrochloride, Statistical significance, Internal medicine, microRNA, Biomarkers, Tumor, Humans, Circulating MicroRNA, MiRNA, Aged, Drug Resistance, Neoplasm, MicroRNAs, Mutation, Protein Kinase Inhibitors, Retrospective Studies, miRNA, business.industry, Carcinoma, Retrospective cohort study, Fold change, respiratory tract diseases, Neoplasm, business, Biomarkers
وصف الملف: application/pdf
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https://research.vumc.nl/en/publications/9f10a1ce-6a0e-421a-b323-08d160a0846fTest -
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المؤلفون: Elisa Giovannetti, Laura L. Meijer, Tessa Y S Le Large, Giulia Mantini, Hanneke W. M. van Laarhoven, Nicole C.T. van Grieken, Bart Kok, Connie R. Jimenez, Jaco C. Knol, Geert Kazemier, Thang V. Pham, Niccola Funel, Sander R. Piersma, Maarten F. Bijlsma
المساهمون: Graduate School, CCA - Cancer biology and immunology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Oncology, Center of Experimental and Molecular Medicine, Radiotherapy, Surgery, Medical oncology laboratory, Pathology, Amsterdam Gastroenterology Endocrinology Metabolism
المصدر: JCI Insight
JCI insight, 5(15):e138290. The American Society for Clinical Investigation
JCI Insight, 5(15):e138290
Le Large, T Y S, Mantini, G, Meijer, L L, Pham, T V, Funel, N, van Grieken, N C T, Kok, B, Knol, J, van Laarhoven, H W M, Piersma, S R, Jimenez, C R, Kazemier, G, Giovannetti, E & Bijlsma, M F 2020, ' Microdissected pancreatic cancer proteomes reveal tumor heterogeneity and therapeutic targets ', JCI Insight, vol. 5, no. 15, e138290 . https://doi.org/10.1172/jci.insight.138290Testمصطلحات موضوعية: 0301 basic medicine, Proteomics, Male, Stromal cell, Proteome, Molecular biology, Biology, Extracellular matrix, 03 medical and health sciences, Mice, 0302 clinical medicine, Stroma, Pancreatic cancer, medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Animals, Humans, Cancer, Aged, Aged, 80 and over, General Medicine, Cell Biology, Middle Aged, medicine.disease, Prognosis, Xenograft Model Antitumor Assays, Extracellular Matrix, Gene Expression Regulation, Neoplastic, Pancreatic Neoplasms, Survival Rate, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Female, Stromal Cells, Carcinoma, Pancreatic Ductal, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bd1e4d181261da5e96c3a6fad92ba2Test
https://pubmed.ncbi.nlm.nih.gov/32634123Test -
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المؤلفون: Yves Mentens, Jose Ferri, Godefridus J. Peters, Elisa Giovannetti, Nele Van Der Steen, Paul Germonpré, M. Ramael, Patrick Pauwels, Leticia G. Leon, David R. Gandara, Christian Rolfo
المساهمون: CCA - Cancer biology and immunology, Medical oncology laboratory, Medical oncology, CCA - Cancer Treatment and quality of life, Amsterdam Gastroenterology Endocrinology Metabolism
المصدر: Van Der Steen, N, Mentens, Y, Ramael, M, Leon, L G, Germonpré, P, Ferri, J, Gandara, D R, Giovannetti, E, Peters, G J, Pauwels, P & Rolfo, C 2018, ' Double Trouble : A Case Series on Concomitant Genetic Aberrations in NSCLC ', Clinical Lung Cancer, vol. 19, no. 1, pp. 35-41 . https://doi.org/10.1016/j.cllc.2017.06.010Test
Clinical Lung Cancer, 19(1), 35-41. Elsevier
Clinical lung cancerمصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Cancer Research, Lung Neoplasms, medicine.medical_treatment, Viral Oncogene, medicine.disease_cause, Targeted therapy, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Exon, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, Genetic Testing, Molecular Targeted Therapy, Epidermal growth factor receptor, Neoplasm Metastasis, Lung cancer, Genetic testing, biology, medicine.diagnostic_test, business.industry, Middle Aged, Proto-Oncogene Proteins c-met, medicine.disease, ErbB Receptors, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, Cancer research, biology.protein, Female, Human medicine, KRAS, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184d2225d523195834ff5aba158882edTest
https://doi.org/10.1016/j.cllc.2017.06.010Test -
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المؤلفون: Elisa Giovannetti, Vanesa Gregorc, Chiara Lazzari, Maria Giulia Cangi, Mariacarmela Santarpia, Alessandra Bulotta
المصدر: Lazzari, C, Gregorc, V, Cangi, M G, Giovannetti, E, Bulotta, A & Santarpia, M 2018, ' Combined exosomal RNA and circulating tumor DNA for epidermal growth factor mutation detection in non-small cell lung cancer ', Journal of Thoracic Disease, vol. 10, pp. S4023-S4027 . https://doi.org/10.21037/jtd.2018.10.17Test
Journal of thoracic disease (Online) 10 (2018): S4023–S4027. doi:10.21037/jtd.2018.10.17
info:cnr-pdr/source/autori:Lazzari C.; Gregorc V.; Cangi M.G.; Giovannetti E.; Bulotta A.; Santarpia M./titolo:Combined exosomal RNA and circulating tumor DNA for epidermal growth factor mutation detection in non-small cell lung cancer/doi:10.21037%2Fjtd.2018.10.17/rivista:Journal of thoracic disease (Online)/anno:2018/pagina_da:S4023/pagina_a:S4027/intervallo_pagine:S4023–S4027/volume:10مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Adult, Male, Lung Neoplasms, DNA Mutational Analysis, Antineoplastic Agents, Exosomes, Sensitivity and Specificity, Circulating Tumor DNA, Epidermal growth factor, Carcinoma, Non-Small-Cell Lung, medicine, ROS1, Biomarkers, Tumor, Anaplastic lymphoma kinase, Humans, Mutation detection, Lung cancer, Aged, Acrylamides, business.industry, Liquid Biopsy, RNA, Genes, erbB-1, Middle Aged, medicine.disease, ErbB Receptors, Editorial, Pyrimidines, Circulating tumor DNA, Cancer research, Female, Non small cell, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85b54e65ba6cced812d1e88976ca0d2Test
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057399178&origin=inwardTest -
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المؤلفون: Michal Stark, Elisa Giovannetti, Gerrit Jansen, Larry H. Matherly, Maria Gemelli, Godefridus J. Peters, Erik Thunnissen, Ittai B. Muller, Zhanjun Hou, P. A. Zucali, E. A. Struys, Niccola Funel, M. Perrino, Yehuda G. Assaraf
المساهمون: Medical oncology laboratory, CCA - Cancer biology and immunology, Pathology, Clinical chemistry, AGEM - Inborn errors of metabolism, AGEM - Endocrinology, metabolism and nutrition, Rheumatology, AGEM - Digestive immunity
المصدر: Annals of Oncology, 28(11), 2725-2732. Oxford University Press
Giovannetti, E, Zucali, P A, Assaraf, Y G, Funel, N, Gemelli, M, Stark, M, Thunnissen, E, Hou, Z, Muller, I B, Struys, E A, Perrino, M, Jansen, G, Matherly, L H & Peters, G J 2017, ' Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma : Clinical evidence and new pharmacological tools ', Annals of Oncology, vol. 28, no. 11, pp. 2725-2732 . https://doi.org/10.1093/annonc/mdx499Testمصطلحات موضوعية: Male, Mesothelioma, 0301 basic medicine, Oncology, Thymidylate synthase, Immunoenzyme Techniques, Reduced Folate Carrier Protein, chemistry.chemical_compound, 0302 clinical medicine, Tumor Cells, Cultured, Aged, 80 and over, biology, Hematology, Methylation, Middle Aged, Prognosis, Survival Rate, Pemetrexed, 030220 oncology & carcinogenesis, Antifolate, Immunohistochemistry, Female, Proton-Coupled Folate Transporter, medicine.drug, Adult, medicine.medical_specialty, Pleural Neoplasms, 03 medical and health sciences, Internal medicine, Biomarkers, Tumor, medicine, Humans, Gene silencing, Survival rate, Aged, Cell Proliferation, business.industry, Original Articles, Thymidylate Synthase, medicine.disease, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, biology.protein, Folic Acid Antagonists, business, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccf6187f967e64fb83a9f2dcd466830Test
https://doi.org/10.1093/annonc/mdx499Test -
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المؤلفون: Henk L. Dekker, Elisa Giovannetti, Marcello Tiseo, Patrick Pauwels, Filip Lardon, Christian Rolfo, Kaylee Keller, Rob Ruijtenbeek, Alessandro Leonetti, Niccola Funel, Godefridus J. Peters, Nele Van Der Steen
المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer biology and immunology
المصدر: Biochemical pharmacology
van der Steen, N, Leonetti, A, Keller, K, Dekker, H, Funel, N, Lardon, F, Ruijtenbeek, R, Tiseo, M, Rolfo, C, Pauwels, P, Peters, G J & Giovannetti, E 2019, ' Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line ', Biochemical Pharmacology, vol. 166, pp. 128-138 . https://doi.org/10.1016/j.bcp.2019.05.014Test
Biochemical Pharmacology, 166, 128-138. Elsevier Inc.مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, Lung Neoplasms, Antineoplastic Agents, Biochemistry, 03 medical and health sciences, Erlotinib Hydrochloride, 0302 clinical medicine, Crizotinib, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Epidermal growth factor receptor, Phosphorylation, Lung cancer, Protein kinase B, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, Aged, Pharmacology, biology, Chemistry, Pharmacology. Therapy, Drug Synergism, Cell cycle, Middle Aged, Proto-Oncogene Proteins c-met, medicine.disease, ErbB Receptors, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, Erlotinib, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198c1da7976161631dcc7ca088486798Test
https://hdl.handle.net/10067/1611930151162165141Test -
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المؤلفون: Marcello Tiseo, Godefridus J. Peters, Paul Germonpré, Christian Rolfo, Nele Van Der Steen, Christophe Hermans, Giulia Mazzaschi, Elisa Giovannetti, Karen Zwaenepoel, Daan P. Geerke, Patrick Pauwels, Paul Van Schil, Ken Op de Beeck, Filip Lardon, Rosa A. Luirink
المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Imaging and biomarkers, AIMMS, Molecular and Computational Toxicology
المصدر: Molecules
Volume 24
Issue 24
Molecules: a journal of synthetic chemistry and natural product chemistry
Molecules, 24(24). Multidisciplinary Digital Publishing Institute
van der Steen, N, Zwaenepoel, K, Mazzaschi, G, A Luirink, R, P Geerke, D, op de Beeck, K, Hermans, C, Tiseo, M, van Schil, P, Lardon, F, Germonpré, P, Rolfo, C, Giovannetti, E, J Peters, G & Pauwels, P 2019, ' The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies ', Molecules, vol. 24, no. 24 . https://doi.org/10.3390/molecules24244443Test
Molecules, 24(24):4443. Multidisciplinary Digital Publishing Institute (MDPI)
Van Der Steen, N, Zwaenepoel, K, Mazzaschi, G, Luirink, R A, Geerke, D P, De Beeck, K O, Hermans, C, Tiseo, M, Van Schil, P, Lardon, F, Germonpré, P, Rolfo, C, Giovannetti, E, Peters, G J & Pauwels, P 2019, ' The role of c-met as a biomarker and player in innate and acquired resistance in non-small-cell lung cancer : Two new mutations warrant further studies ', Molecules, vol. 24, no. 24, 4443 . https://doi.org/10.3390/molecules24244443Testمصطلحات موضوعية: Male, Lung Neoplasms, Mutant, Pharmaceutical Science, NSCLC, Analytical Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Drug Discovery, Epidermal growth factor receptor, Neoplasm Metastasis, Receptor, 0303 health sciences, biology, Middle Aged, Proto-Oncogene Proteins c-met, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, Chemistry, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Molecular Medicine, Biomarker (medicine), Female, Antibody, Adult, C-Met, EGFR, Article, Deep sequencing, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Biomarkers, Tumor, medicine, Humans, Physical and Theoretical Chemistry, Lung cancer, Biology, Aged, 030304 developmental biology, business.industry, Organic Chemistry, Gene Amplification, medicine.disease, chemistry, Drug Resistance, Neoplasm, Mutation, biology.protein, Cancer research, Tumor Suppressor Protein p53, business, Biomarkers
وصف الملف: application/pdf
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المؤلفون: C. J. van Groeningen, Elisa Giovannetti, G.J. Peters, R. Ruijter, Henk M.W. Verheul, Giuseppe Giaccone, A. A. van Zweeden, Richard J. Honeywell, Carolien H. Smorenburg, Hans J. van der Vliet
المساهمون: Medical oncology, Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer Treatment and quality of life
المصدر: van Zweeden, A A, van Groeningen, C J, Honeywell, R J, Giovannetti, E, Ruijter, R, Smorenburg, C H, Giaccone, G, Verheul, H M W, Peters, G J & van der Vliet, H J 2018, ' Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer ', Cancer Chemotherapy and Pharmacology, vol. 82, no. 1, pp. 39-48 . https://doi.org/10.1007/s00280-018-3588-6Test
Cancer Chemotherapy and Pharmacology
Cancer Chemotherapy and Pharmacology, 82(1), 39-48. Springer Verlagمصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, medicine.medical_specialty, Folic acid, Esophageal Neoplasms, Esophagogastric cancer, Cmax, Phases of clinical research, Adenocarcinoma, Toxicology, Gastroenterology, Deoxycytidine, 03 medical and health sciences, 0302 clinical medicine, Stomach Neoplasms, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Clinical endpoint, Humans, Pharmacology (medical), Vitamin B12, Aged, Pharmacology, Cisplatin, Aged, 80 and over, business.industry, Drug Synergism, Middle Aged, medicine.disease, Gemcitabine, Vitamin B 12, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Toxicity, Dietary Supplements, Original Article, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502b3d61670f51491c3457468559503Test
https://research.vumc.nl/en/publications/2bf1b93c-372d-48e0-ac96-fc8c6c2699d3Test -
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المؤلفون: Godefridus J. Peters, Isabella Vittimberga, Editta Baldini, Myriam Chartoire, Luca Boni, Marcello Tiseo, Matteo Brighenti, Fausto Barbieri, Andrea Camerini, Elisa Giovannetti, Francesca Mazzoni, Carmelo Tibaldi, Annalisa Gilli, Richard J. Honeywell
المساهمون: CCA - Imaging and biomarkers, Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system
المصدر: British journal of cancer, 119(11), 1326-1331. Nature Publishing Group
British Journal of Cancer, 119(11), 1326-1331. Nature Publishing Group
Tibaldi, C, Camerini, A, Tiseo, M, Mazzoni, F, Barbieri, F, Vittimberga, I, Brighenti, M, Boni, L, Baldini, E, Gilli, A, Honeywell, R, Chartoire, M, Peters, G J, Giovannetti, E & Italian Oncological Group of Clinical Research (GOIRC) 2018, ' Cytidine deaminase enzymatic activity is a prognostic biomarker in gemcitabine/platinum-treated advanced non-small-cell lung cancer : a prospective validation study ', British Journal of Cancer, vol. 119, no. 11, pp. 1326-1331 . https://doi.org/10.1038/s41416-018-0307-3Test
British Journal of Cancerمصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Predictive markers, Deoxycytidine, Article, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Medical research, Internal medicine, Carcinoma, Non-Small-Cell Lung, Cytidine Deaminase, Antineoplastic Combined Chemotherapy Protocols, medicine, Carcinoma, Biomarkers, Tumor, Humans, Prospective Studies, Prospective cohort study, Lung cancer, Survival rate, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Retrospective cohort study, Cytidine deaminase, Middle Aged, medicine.disease, Prognosis, Gemcitabine, 030104 developmental biology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, Cisplatin, business, Non-small-cell lung cancer, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a41cf0b0a4002de132af4198423642Test
https://pure.amc.nl/en/publications/cytidine-deaminase-enzymatic-activity-is-a-prognostic-biomarker-in-gemcitabineplatinumtreated-advanced-nonsmallcell-lung-cancer-a-prospective-validation-studyTest(297ba0b2-d07b-4b73-bc30-89fce3b095d5).html -
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المؤلفون: Carlotta Granchi, Elisa Giovannetti, Amir Avan, Babette Aicher, Daniela Massihnia, Mina Maftouh, Leticia G. Leon, Rajiv S. Raktoe, Anne van Krieken, Niccola Funel, Filippo Minutolo, Antonio Russo, Ugo Boggi, Godefridus J. Peters
المساهمون: Massihnia, D., Avan, A., Funel, N., Maftouh, M., Van Krieken, A., Granchi, C., Raktoe, R., Boggi, U., Aicher, B., Minutolo, F., Russo, A., Leon, L., Peters, G., Giovannetti, E., CCA - Cancer biology and immunology, AGEM - Digestive immunity, Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system
المصدر: Massihnia, D, Avan, A, Funel, N, Maftouh, M, Van Krieken, A, Granchi, C, Raktoe, R, Boggi, U, Aicher, B, Minutolo, F, Russo, A, Leon, L G, Peters, G J & Giovannetti, E 2017, ' Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer ', Journal of Hematology and Oncology, vol. 10, no. 1, 9 . https://doi.org/10.1186/s13045-016-0371-1Test
Journal of Hematology & Oncology
Journal of Hematology and Oncology, 10(1):9. BioMed Central
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-17 (2017)مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Biopsy, AKT1, Apoptosis, Akt, Gemcitabine, Pancreatic ductal adenocarcinoma, Synergism, Hematology, Molecular Biology, Deoxycytidine, 0302 clinical medicine, Cell Movement, Tumor Cells, Cultured, Glucose Transporter Type 1, medicine.diagnostic_test, Chemistry, Cell Cycle, Pancreatic Neoplasm, Drug Synergism, lcsh:Diseases of the blood and blood-forming organs, Cell cycle, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Aged, Carcinoma, Pancreatic Ductal, Female, Humans, Pancreatic Neoplasms, Phosphoproteins, Proto-Oncogene Proteins c-akt, RNA, Messenger, Spheroids, Cellular, 030220 oncology & carcinogenesis, Phosphoprotein, medicine.drug, Human, medicine.medical_specialty, Prognosi, lcsh:RC254-282, Flow cytometry, 03 medical and health sciences, Internal medicine, Pancreatic cancer, medicine, Protein kinase B, PI3K/AKT/mTOR pathway, lcsh:RC633-647.5, Research, Apoptosi, medicine.disease, 030104 developmental biology, Cancer cell, Cancer research
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0527d043c396c119ac955e1ab571ea8Test
https://research.vumc.nl/en/publications/e3915272-5f2e-4b5f-a149-4af093da963cTest
