نتائج البحث - "David Neal Franz"

1

Cannabidiol Elevates Mechanistic Target of Rapamycin Inhibitor Levels in Patients With Tuberous Sclerosis Complex

المؤلفون: David Neal Franz, Karen Agricola, Cynthia Tudor, Daniel Ebrahimi-Fakhari, Darcy A. Krueger

المصدر: Pediatric neurology. 105

مصطلحات موضوعية: Adult, Male, Adolescent, Pharmacology, 03 medical and health sciences, Tuberous sclerosis, Young Adult, 0302 clinical medicine, Developmental Neuroscience, Tuberous Sclerosis, 030225 pediatrics, medicine, Cannabidiol, Humans, Drug Interactions, Everolimus, Adverse effect, Child, Mechanistic target of rapamycin, Protein Kinase Inhibitors, Sirolimus, biology, business.industry, TOR Serine-Threonine Kinases, Middle Aged, medicine.disease, Neurology, Child, Preschool, Pediatrics, Perinatology and Child Health, Toxicity, Lymphangioleiomyomatosis, biology.protein, Anticonvulsants, Drug Therapy, Combination, Female, Neurology (clinical), business, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbb2387e40b9232f862c00834a7dcacTest
https://pubmed.ncbi.nlm.nih.gov/31924480Test

2

Everolimus dosing recommendations for tuberous sclerosis complex–associated refractory seizures

المؤلفون: Neva Coello, Maurizio Voi, Kai Grosch, David Neal Franz, Christian Brandt, Zuhal Yapici, John A. Lawson, Jacqueline A. French, Michael Kohrman, Michael Wong, Wing Cheung, Adelheid Wiemer-Kruel, Mathieu Milh

المصدر: Epilepsia

مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Time Factors, Adolescent, TDM, 03 medical and health sciences, Cmin, Young Adult, 0302 clinical medicine, Double-Blind Method, Seizures, Tuberous Sclerosis, Internal medicine, Linear regression, medicine, Humans, Dosing, Everolimus, Adverse effect, Child, TSC, medicine.diagnostic_test, Dose-Response Relationship, Drug, Proportional hazards model, business.industry, dose, Age Factors, Cytochrome P-450 CYP3A Inducers, Middle Aged, refractory, Neurology, Therapeutic drug monitoring, 030220 oncology & carcinogenesis, Concomitant, Child, Preschool, Full‐length Original Research, Female, Neurology (clinical), Drug Monitoring, business, 030217 neurology & neurosurgery, Immunosuppressive Agents, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85269570c88949365f781d57c01f2b7Test
http://europepmc.org/articles/PMC6033043Test

3

Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study

المؤلفون: Noah Berkowitz, Petrus J. de Vries, David Neal Franz, Zuhal Yapici, John A. Lawson, Rima Nabbout, Dennis J. Dlugos, Maurizio Voi, Severine Peyrard, Paolo Curatolo, Hiroko Ikeda, Diana Pelov, Tilman Polster, Jacqueline A. French

المصدر: The Lancet. 388:2153-2163

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, Placebo-controlled study, Antineoplastic Agents, Placebo, law.invention, 03 medical and health sciences, Tuberous sclerosis, 0302 clinical medicine, Double-Blind Method, Randomized controlled trial, Seizures, Tuberous Sclerosis, law, Internal medicine, Humans, Medicine, Combined Modality Therapy, Everolimus, Child, Aged, Medicine(all), Dose-Response Relationship, Drug, business.industry, General Medicine, Middle Aged, medicine.disease, Settore MED/39 - Neuropsichiatria Infantile, Surgery, Clinical trial, 030104 developmental biology, Child, Preschool, Concomitant, Anticonvulsants, Female, business, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4c6c454633f380d955764e6ceac4e1Test
https://doi.org/10.1016/s0140-6736Test(16)31419-2

4

Lymphangioleiomyomatosis Mortality in Patients with Tuberous Sclerosis Complex

المؤلفون: Nishant Gupta, Weiji Su, David Neal Franz, Francis X. McCormack, Sara Mary Zak, Maxwell Mays, Rhonda D. Szczesniak, Nadine Mokhallati, Darcy A. Krueger

المصدر: Annals of the American Thoracic Society. 16(4)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59e9d4adf5e916e70db4bfe19a3071bTest
https://pubmed.ncbi.nlm.nih.gov/30571922Test

5

Effect of everolimus on renal function in patients with tuberous sclerosis complex: evidence from EXIST-1 and EXIST-2

المؤلفون: Matthias Sauter, Michael Frost, David Neal Franz, Bernard A. Zonnenberg, J. Christopher Kingswood, John J. Bissler, Noah Berkowitz, Elena Belousova, Klemens Budde, Antonia Ridolfi

المصدر: Nephrology Dialysis Transplantation

مصطلحات موضوعية: Male, 030232 urology & nephrology, 030204 cardiovascular system & hematology, urologic and male genital diseases, Kidney, Tuberous sclerosis, chemistry.chemical_compound, 0302 clinical medicine, Lymphangioleiomyomatosis, Child, Proteinuria, Middle Aged, Kidney Neoplasms, medicine.anatomical_structure, Nephrology, Child, Preschool, Female, medicine.symptom, Immunosuppressive Agents, Glomerular Filtration Rate, Adult, medicine.medical_specialty, Adolescent, Renal Hemorrhage, Angiomyolipoma, Urology, Renal function, Antineoplastic Agents, tuberous sclerosis, Astrocytoma, Nephrotoxicity, 03 medical and health sciences, Young Adult, Double-Blind Method, Clinical Research, medicine, Humans, Everolimus, Renal Insufficiency, Chronic, Retrospective Studies, Transplantation, Creatinine, business.industry, renal function, Infant, medicine.disease, chemistry, Kidney Failure, Chronic, mTOR inhibition, ORIGINAL ARTICLES, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b5ead399d52f64c834878ca1799f8eTest
https://pubmed.ncbi.nlm.nih.gov/30053159Test

6

Pooled analysis of menstrual irregularities from three major clinical studies evaluating everolimus for the treatment of tuberous sclerosis complex

المؤلفون: Karin Burock, J. Christopher Kingswood, Steven Sparagana, Noah Berkowitz, John J. Bissler, Darcy A. Krueger, David Neal Franz

المصدر: PLoS ONE, Vol 12, Iss 10, p e0186235 (2017)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Pediatrics, Physiology, Peptide Hormones, lcsh:Medicine, Drug research and development, Biochemistry, Giant Cells, Menstruation, Follicle-stimulating hormone, 0302 clinical medicine, Endocrinology, Clinical trials, Tuberous Sclerosis, Reproductive Physiology, Animal Cells, Medicine and Health Sciences, Multicenter Studies as Topic, Prospective cohort study, Child, lcsh:Science, Neurological Tumors, Menstruation Disturbances, Multidisciplinary, Incidence, Middle Aged, Phase III clinical investigation, Oncology, Neurology, Genetic Diseases, Research Design, 030220 oncology & carcinogenesis, Menarche, Amenorrhea, Female, medicine.symptom, Cellular Types, Infertility, Female, Phase II clinical investigation, medicine.drug, Research Article, Adult, medicine.medical_specialty, Adolescent, Clinical Research Design, Astrocytoma, 03 medical and health sciences, Clinical Trials, Phase II as Topic, medicine, Humans, Everolimus, Menstrual Cycle, Gynecology, Clinical Genetics, Pharmacology, Subependymal giant cell astrocytoma, Endocrine Physiology, business.industry, lcsh:R, Biology and Life Sciences, Cancers and Neoplasms, Cell Biology, Luteinizing Hormone, medicine.disease, Hormones, Research and analysis methods, Irregular menstruation, 030104 developmental biology, Clinical Trials, Phase III as Topic, Clinical medicine, lcsh:Q, Adverse Events, Follicle Stimulating Hormone, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e784a16c61434d03425063149ad2bacTest
http://europepmc.org/articles/PMC5638404?pdf=renderTest

7

Utility of [ 18 F]2-Fluoro-2-Deoxyglucose-PET in Sporadic and Tuberous Sclerosis-Associated Lymphangioleiomyomatosis

المؤلفون: Christopher D.M. Fletcher, Francis X. McCormack, Matthew D. Galsky, Thomas C. Corbridge, Michael J. Gelfand, David Neal Franz, Preeti Nagarkatte, Lisa R. Young, Kathryn A. Wikenheiser-Brokamp, Anna P. Lam

المصدر: Chest. 136:926-933

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c344858eb2beca669c097677d815f9Test
https://doi.org/10.1378/chest.09-0336Test

8

Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis

المؤلفون: Francis X. McCormack, John J. Bissler, Judy A. Bean, Jennifer Leonard, Shelia Salisbury, Tal Laor, Jean M. Elwing, Gail Chuck, Alan S. Brody, Vincent J. Schmithorst, David Neal Franz, Lisa R. Young

المصدر: New England Journal of Medicine. 358:140-151

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d842da10e6cb2fd0c7deafafddf057Test
https://doi.org/10.1056/nejmoa063564Test

9

Mutational and Radiographic Analysis of Pulmonary Disease Consistent with Lymphangioleiomyomatosis and Micronodular Pneumocyte Hyperplasia in Women with Tuberous Sclerosis

المؤلفون: Francis X. McCormack, David Neal Franz, Gail Chuck, Alan S. Brody, Jennifer Leonard, Gopalan Sethuraman, Sandra L. Dabora, Cristopher A. Meyer, David J. Kwiatkowski, Thomas V. Colby

المصدر: Scopus-Elsevier

مصطلحات موضوعية: Adult, Pulmonary and Respiratory Medicine, Pathology, medicine.medical_specialty, Lung Neoplasms, Angiomyolipoma, Adolescent, Genotype, DNA Mutational Analysis, Critical Care and Intensive Care Medicine, Pulmonary function testing, Tuberous sclerosis, Tuberous Sclerosis, hemic and lymphatic diseases, Prevalence, medicine, Humans, Cyst, Prospective Studies, Solitary pulmonary nodule, Hyperplasia, business.industry, Respiratory disease, Solitary Pulmonary Nodule, Middle Aged, medicine.disease, Pedigree, Respiratory Function Tests, Pulmonary Alveoli, Spirometry, Multifocal micronodular pneumocyte hyperplasia, Lymphangioleiomyomatosis, Female, Kidney Diseases, Tomography, X-Ray Computed, business, Lymphangiomyoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc06d9c0b5d7281ed261233beb02b9a9Test
https://doi.org/10.1164/ajrccm.164.4.2011025Test

10

Lymphangioleiomyomatosis screening in women with tuberous sclerosis

المؤلفون: Corey J. Cudzilo, John J. Bissler, Darcy A. Krueger, Lisa R. Young, Rhonda D. Szczesniak, Alan S. Brody, David Neal Franz, Francis X. McCormack, Mantosh S. Rattan

المصدر: Chest. 144(2)

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Adult, medicine.medical_specialty, Adolescent, Population, Chest ct, Computed tomography, Critical Care and Intensive Care Medicine, Asymptomatic, Tuberous sclerosis, immune system diseases, Tuberous Sclerosis, hemic and lymphatic diseases, Female patient, medicine, Prevalence, Humans, Cyst, Lymphangioleiomyomatosis, education, Ohio, Retrospective Studies, education.field_of_study, medicine.diagnostic_test, business.industry, Middle Aged, bacterial infections and mycoses, medicine.disease, lipids (amino acids, peptides, and proteins), Female, Radiology, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Tomography, X-Ray Computed

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947de40faa6a087ac69c9bb7bc118962Test
https://pubmed.ncbi.nlm.nih.gov/23539171Test

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