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المؤلفون: Sylwia Kopijasz, Corran Roberts, Victoria Y Strauss, Shibani Nicum, Andrew R Clamp, Marcia Hall, Richard D. Kennedy, Ana Montes, Charlie Gourley, Jacinta Abraham, Michael R.L. Stratford, Susana Banerjee, Lisa K. Folkes
المصدر: Roberts, C, Strauss, V Y, Kopijasz, S, Gourley, C, Hall, M, Montes, A, Abraham, J, Clamp, A, Kennedy, R, Banerjee, S, Folkes, L K, Stratford, M & Nicum, S 2020, ' Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours ', British Journal of Cancer, vol. 122, no. 4, pp. 483-490 . https://doi.org/10.1038/s41416-019-0674-4Test, https://doi.org/10.1038/s41416-019-0674-4Test
Roberts, C, Strauss, V Y, Kopijasz, S, Gourley, C, Hall, M, Montes, A, Abraham, J, Clamp, A, Kennedy, R, Banerjee, S, Folkes, L K, Stratford, M & Nicum, S 2020, ' Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours ', British Journal of Cancer, vol. 122, no. 4, pp. 483-490 . https://doi.org/10.1038/s41416-019-0674-4Test
British Journal of Cancerمصطلحات موضوعية: Adult, Oncology, medicine.medical_specialty, Cancer Research, Cancer therapy, medicine.medical_treatment, Breast Neoplasms, Gene mutation, Article, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, SDG 3 - Good Health and Well-being, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Humans, Medicine, Aged, 030304 developmental biology, BRCA2 Protein, Ovarian Neoplasms, Salvage Therapy, Cisplatin, 0303 health sciences, Chemotherapy, BRCA1 Protein, Mercaptopurine, business.industry, Middle Aged, medicine.disease, Progression-Free Survival, Cancer therapeutic resistance, Methotrexate, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, PARP inhibitor, Female, Neoplasm Recurrence, Local, business, Ovarian cancer, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b494bdec4a88dbce8776a6e9b65b9cTest
https://doi.org/10.1038/s41416-019-0674-4Test -
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المؤلفون: Jane Holmes, Leena Elhussein, Claire Brooks, Tim Maughan, Corran Roberts, Tim Coutts, S.M. Ng, Nicholas F. Brown, Peter Hoskin, Paul Mulholland, Sarah P. Blagden
المصدر: BMC Cancer
Brown, N F, Ng, S M, Brooks, C, Coutts, T, Holmes, J, Roberts, C, Elhussein, L, Hoskin, P, Maughan, T, Blagden, S & Mulholland, P 2020, ' A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma : The Ipi-Glio trial protocol ', BMC Cancer, vol. 20, no. 1, 198 . https://doi.org/10.1186/s12885-020-6624-yTest
BMC Cancer, Vol 20, Iss 1, Pp 1-5 (2020)مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, medicine.medical_specialty, Ipilimumab, lcsh:RC254-282, 03 medical and health sciences, Study Protocol, Young Adult, 0302 clinical medicine, Surgical oncology, Glioma, Genetics, medicine, Temozolomide, Humans, Adverse effect, Aged, Manchester Cancer Research Centre, business.industry, Brain Neoplasms, Standard treatment, ResearchInstitutes_Networks_Beacons/mcrc, Chemoradiotherapy, Cytoreduction Surgical Procedures, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Debulking, Survival Analysis, United Kingdom, Surgery, 030104 developmental biology, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Female, business, Glioblastoma, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b75e328f376518aaf00b055e9ba51b3Test
http://europepmc.org/articles/PMC7068928Test -
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المؤلفون: Alison Kennedy, Aimee E Houlton, Paul Ferguson, Michael Dennis, Marlen Metzner, Shamyla Siddique, Sandeep Nagra, Keith Wheatley, Natalia Garcia-Martin, Mary Frances McMullin, Lynn Quek, Srinivas Pillai, Jamie Cavenagh, Emma Gbandi, Manoj Raghavan, Richard Kelly, Corran Roberts, Louise Dudley, Angela Hamblin, Paresh Vyas, Charles Craddock
المصدر: Craddock, C, Houlton, A E, Quek, L S, Ferguson, P, Gbandi, E, Roberts, C, Metzner, M, Garcia-Martin, N, Kennedy, A, Hamblin, A, Raghavan, M, Nagra, S, Dudley, L, Wheatley, K, McMullin, M, Pillai, S P, kelly, R J, Siddique, S, Dennis, M, Cavenagh, J D & Vyas, P 2017, ' Outcome of azacitidine therapy in acute myeloid leukaemia is not improved by concurrent vorinostat therapy but is predicted by a diagnostic molecular signature ', Clinical Cancer Research . https://doi.org/10.1158/1078-0432.CCR-17-1423Test
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Myeloid, Azacitidine, Hydroxamic Acids, Disease-Free Survival, Drug Administration Schedule, 03 medical and health sciences, 0302 clinical medicine, Immunophenotyping, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Cyclin-Dependent Kinase Inhibitor p18, Humans, Progenitor cell, neoplasms, Vorinostat, Cyclin-Dependent Kinase Inhibitor p16, Aged, business.industry, Cancer, Myeloid leukemia, Middle Aged, medicine.disease, Combined Modality Therapy, Isocitrate Dehydrogenase, Histone Deacetylase Inhibitors, Leukemia, Myeloid, Acute, Leukemia, Treatment Outcome, Editorial, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mutation, Immunology, Female, Tumor Suppressor Protein p53, business, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26326dd64b25e6545090d1d151ab6d82Test
https://doi.org/10.1158/1078-0432.ccr-17-1423Test -
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المؤلفون: Stephen Falk, Susan J Dutton, Wasat Mansoor, David A J Stevenson, Caroline Clark, Russell D. Petty, Aileen Osborne, Asa Dahle-Smith, Angel Garcia-Alonso, Mark Harrison, Joyce Thompson, Graeme I. Murray, Ian Chau, Irene Chong, Jonathan Wadsley, Corran Roberts, Doreen Massie, Zosia Miedzybrodzka, Anirban Chatterjee, Sean Elyan, David Walter Fyfe, David Ferry
المصدر: Journal of Clinical Oncology. 35:2279-2287
مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, Esophageal Neoplasms, DNA Mutational Analysis, Gene Dosage, medicine.disease_cause, Tyrosine-kinase inhibitor, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Medicine, Single-Blind Method, Epidermal growth factor receptor, In Situ Hybridization, Fluorescence, Randomized Controlled Trials as Topic, biology, Gefitinib, Middle Aged, Esophageal cancer, ErbB Receptors, Survival Rate, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, Female, KRAS, Signal Transduction, medicine.drug, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Class I Phosphatidylinositol 3-Kinases, medicine.drug_class, Antineoplastic Agents, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Internal medicine, Biomarkers, Tumor, Humans, neoplasms, Survival rate, Aged, business.industry, Gene Amplification, Cancer, Genes, erbB-1, medicine.disease, respiratory tract diseases, 030104 developmental biology, Clinical Trials, Phase III as Topic, Mutation, Quinazolines, biology.protein, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8371b4cd78ae0dea0b7758a0d5bded2bTest
https://doi.org/10.1200/jco.2016.70.3934Test -
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المؤلفون: Corran Roberts, Adelyn Wise, Charles Kelly, Carie Corner, Finn Tysoe, J. Lester, Martha Woodward, Avinash Gupta, Ernie Marshall, Sharon Love, Jenny Nobes, L Collins, M Goff, Mark R. Middleton, Amanda Salisbury, Virginia Wolstenholme
المصدر: British Journal of Cancer
مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, vandetanib, Radiation-Sensitizing Agents, education, Antineoplastic Agents, Vandetanib, Disease-Free Survival, law.invention, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Randomized controlled trial, Double-Blind Method, Piperidines, law, Internal medicine, brain metastases, medicine, melanoma, Humans, Lung cancer, Aged, Cervical cancer, Aged, 80 and over, Radiotherapy, business.industry, Brain Neoplasms, Melanoma, Brain, trial, Middle Aged, medicine.disease, Combined Modality Therapy, Clinical trial, 030104 developmental biology, phase 2, 030220 oncology & carcinogenesis, Clinical Study, Quinazolines, Female, Skin cancer, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34ce1a018b44ba5680dee61cc8b7282Test
http://europepmc.org/articles/PMC5104891Test -
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المؤلفون: Jim Murray, Graham P. Collins, Andrew R. Pettitt, Maite Cabes, George A Follows, Helen McCarthy, Elizabeth Soilleux, Basile Stamatopoulos, Lucy Boyle, Chris Hatton, John G. Gribben, R Clifford, Christopher P. Fox, Anna Schuh, Toby A. Eyre, Stephen Devereux, Corran Roberts, Peter Hillmen, Adrian Bloor, Tim Littlewood, Sharon Love, Andrew Wotherspoon
المصدر: BRITISH JOURNAL OF HAEMATOLOGY
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Lymphoma, Phases of clinical research, CHOP, Antibodies, Monoclonal, Humanized, Ofatumumab, Maintenance Chemotherapy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Prednisone, Positron Emission Tomography Computed Tomography, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Cyclophosphamide, Aged, Neoplasm Staging, Aged, 80 and over, business.industry, Antibodies, Monoclonal, Induction chemotherapy, Induction Chemotherapy, Syndrome, Hematology, Middle Aged, Leukemia, Lymphocytic, Chronic, B-Cell, Survival Analysis, Fludarabine, Surgery, Regimen, Treatment Outcome, chemistry, Doxorubicin, Vincristine, 030220 oncology & carcinogenesis, Disease Progression, Prednisolone, Female, business, Biomarkers, 030215 immunology, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f3182a832d6254e3dacb6f678c165dTest
http://livrepository.liverpool.ac.uk/3026122/1/Eyre_et_al-2016-British_Journal_of_Haematology.pdfTest -
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المؤلفون: C. J. Vickery, M. J. Lamparelli, R. Gupta, G. Maskell, A. C. Bateman, M. L. Hughes, Michael Braun, D. A. Agbamu, H. O'Neill, J. H. Scholefield, W. Faux, A. S. Myint, C. Macklin, H. J. Pearson, P. Richman, Geraint T. Williams, S. Sukumar, A. Kawesha, J. Robinson, Dion Morton, Caroline Finlayson, M. Saeed, A. Anathhanam, D. M. Melville, J. Whalley, Rizvana Ahmad, V. Howarth, E. Favill, Jacob G. Scott, M. Scott, D. Eason, S. M. Ahmad, Rajarshi Roy, M. Gupta, F. Lofts, N. Beharry, N. Lees, M. Charig, A. Buxton, Fiona Campbell, K. G. Walker, M. Train, P. Nichols, J. Mathew, G. Stenhouse, J. Orrell, P. Burn, D. Peake, S. P. Lake, D. Ilsley, A. J. Watson, A Mayer, A C Wotherspoon, David J. Smith, A. K. Thompson, J. Gutmann, W. K. Dunn, J. Huang, Tracy E Roberts, L. Meleagros, D. Cowlishaw, Angela E Taylor, P. Chandran, C. Bronder, B. Fozard, Jurjees Hasan, S. J. Needham, Rob Glynne-Jones, Jonathan Wadsley, F. Adab, J. Ostrowski, Andrew Bateman, I. T. Saeed, David Cunningham, E. Loveday, David Ferry, A. Hartley, K. Sleigh, A. Page, I. C. Ilesley, P. Cohen, D. Whillis, Phillipe Taniere, Paul J. Finan, S. Pritchard, S. Lee, A. Zaitoun, J. A. Rees, G. Langman, G. Howarth, D. Pai, D. Blunt, R. Osborne, W. Atkinson, D. Barber, O. A. Ogunbiyi, J. Harrison, H. Burnett, V. Sundaresan, S. Hayes, J. Livingstone, Simon Gollins, F. Daniel, G. Kurien, C. Holland, I. Britton, A. Sherif, Clifton D. Fuller, D. Shareef, Matthew T. Seymour, J. McCutcheon, C. Phelan, Charles Lowdell, R. M. Blaquiere, J. Alexander, A. Hamid, Sherif Raouf, A. Baxter, Tamas Hickish, Joanne Hornbuckle, A. Pallan, J. R.G. Bell, Graham Branagan, D. Tolan, A. Moss, J. Hampton, C. W. Hendrickse, D. Furniss, T. Burdge, Carolyn S. Hall, J. Watkins, C. Barlow, J. Hartley, P. Rooney, B. Pravee, Anne Pullyblank, C. Corr, A. Chiphang, J. Walther, Paris P. Tekkis, M. J. Dworkin, D. Eaton, R. Hagger, J. Mikel, A. Coup, M. Peters, S. Muzaffar, Sujal R. Desai, D. Tarver, C. Ramsey, Sarah Smith, J. Geraghty, N. Mapstone, Corran Roberts, John Bridgewater, S. Amin, P. Dawson, Vanessa Potter, C. J. Walsh, M. Pitt, N. Woodcock, S. Ramesh, Charlotte Rees, Nigel Scott, N. Steven, A. Maw, D. P. O'Leary, David Farrugia, S. Cook, D. Tsang, M. Callaway, P. Taylor, Andrew J. Hall, S. R. Muthuramalingam, S. A.M. Mangalika, N. Cruickshank, U. Raja, M. Dobson, C. Bale, R. W. Talbot, M. Qaiyum, M. Crabtree, Stephen H D Jackson, J. Hyde, S. Snape, Richard J. Ellis, R. Borgstein, A. Higginson, M. Thyveetil, Michael Thomas, A. Lowe, W. Partridge, Gina Brown, A. W. MacDonald, O. Lalude, M. Clwyd, Brendan J. Moran, G. T. Smith, Samir Mehta, B. T. Ismail, R. Donovan, P. Kitsanta, E. Kweka, N. Scot, K. Hopkins, N. Rooney, A. L. Desai, S. Jain, N. Wong, T. Iveson, Rubin Soomal, R. D. Taraporewalla, A. Clarke, J. Brittenden, S. Dundas, Marcia Hall, J. Denson, N. Day, Simon Aird Grumett, R. Church, M. Zeiderman, M. Steward, Daniel Swinson, S. Susnerwala, Stephen Falk, A. Malhotra, D. White, N. Pranesh, J. Haselden, James Hill, D. Scullion
المصدر: The Lancet Oncology. 13:1152-1160
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Organoplatinum Compounds, Colorectal cancer, medicine.medical_treatment, law.invention, Randomized controlled trial, law, Antineoplastic Combined Chemotherapy Protocols, Humans, Medicine, Neoadjuvant therapy, Aged, Neoplasm Staging, Aged, 80 and over, Intention-to-treat analysis, Rectal Neoplasms, business.industry, Panitumumab, Antibodies, Monoclonal, Perioperative, Middle Aged, medicine.disease, Combined Modality Therapy, Neoadjuvant Therapy, Surgery, Oxaliplatin, Radiation therapy, Oncology, Colonic Neoplasms, Preoperative Period, Resection margin, Female, Fluorouracil, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c179d79bec2b424eaa6df5c9ef3b22Test
https://doi.org/10.1016/s1470-2045Test(12)70348-0 -
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المؤلفون: Oliver, Old, Paul, Moayyedi, Sharon, Love, Corran, Roberts, Julie, Hapeshi, Chris, Foy, Clive, Stokes, Andrew, Briggs, Janusz, Jankowski, Hugh, Barr, Mohamed, Yousif
المصدر: Journal of medical screening. 22(3)
مصطلحات موضوعية: Research design, Adult, Male, Risk, medicine.medical_specialty, Esophageal Neoplasms, Cost-Benefit Analysis, Oesophageal adenocarcinoma, Adenocarcinoma, law.invention, Barrett Esophagus, Young Adult, Randomized controlled trial, law, medicine, Humans, Early Detection of Cancer, Aged, medicine.diagnostic_test, business.industry, Health Policy, Public Health, Environmental and Occupational Health, Follow up studies, Endoscopy, Middle Aged, medicine.disease, Surgery, Treatment Outcome, Research Design, Barrett's oesophagus, Disease Progression, Female, Malignant progression, business, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaba8710aab170f00e8472682d7df702Test
https://pubmed.ncbi.nlm.nih.gov/25767103Test