المؤلفون: La Regina G., Bai R., Rensen W., Coluccia A., Piscitelli F., Gatti V., Bolognesi A., Granata I., Porta A., Maresca B., Soriani A., Iannitto M. L., Mariani M., Santoni A., Brancale A., Ferlini C., Dondio G., Varasi M., Mercurio C., Hamel E., Lavia P., Silvestri R., LAVECCHIA, ANTONIO, NOVELLINO, ETTORE

المساهمون: La Regina, G., Bai, R., Rensen, W., Coluccia, A., Piscitelli, F., Gatti, V., Bolognesi, A., Lavecchia, Antonio, Granata, I., Porta, A., Maresca, B., Soriani, A., Iannitto, M. L., Mariani, M., Santoni, A., Brancale, A., Ferlini, C., Dondio, G., Varasi, M., Mercurio, C., Hamel, E., Lavia, P., Novellino, Ettore, Silvestri, R.

مصطلحات موضوعية: Cancer Cell, Anticancer Agent, Antimitotic Drug, Breast Cancer, Microtubule, Colchicine, Indole, Docking

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000297946300016; volume:54; issue:24; firstpage:8394; lastpage:8406; numberofpages:13; journal:JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11588/415081Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84055211830

الإتاحة: https://doi.org/10.1021/jm2012886Test
http://hdl.handle.net/11588/415081Test

المؤلفون: La Regina G., Masci D., Martini C.

المساهمون: La Regina, Giuseppe, Bai, R., Coluccia, A., Naccarato, V., Famiglini, V., Nalli, M., Masci, Domiziana, Verrico, A., Rovella, P., Mazzoccoli, C., Da Pozzo, E., Cavallini, C., Martini, Maria Cristina, Vultaggio, S., Dondio, G., Varasi, M., Mercurio, C., Hamel, E., Lavia, P., Silvestri, R.

مصطلحات موضوعية: Cancer cell, Indole, Inhibitor, Microtubule, Tubulin, Antineoplastic Agents, Cell Proliferation, Cell Survival, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, Humans, Indoles, Molecular Structure, Polymerization, Structure-Activity Relationship, Tubulin Modulators, Tumor Cells, Cultured, Settore CHIM/08 - CHIMICA FARMACEUTICA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29730191; info:eu-repo/semantics/altIdentifier/wos/WOS:000435048900023; volume:152; issue:May; firstpage:283; lastpage:297; numberofpages:15; issueyear:2018; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/10807/195403Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85046738606; https://www.sciencedirect.com/science/article/pii/S0223523418303763Test

الإتاحة: https://doi.org/10.1016/j.ejmech.2018.04.042Test
https://hdl.handle.net/10807/195403Test
https://www.sciencedirect.com/science/article/pii/S0223523418303763Test

المؤلفون: Angela Santoni, Alessandra Soriani, Romano Silvestri, Bruno Maresca, Cristiano Ferlini, Valerio Gatti, Ruoli Bai, Ciro Mercurio, Willeke Rensen, Antonio Lavecchia, Giulio Dondio, Francesco Piscitelli, Ernest Hamel, Alessio Bolognesi, Maria Luisa Iannitto, Mario Varasi, Patrizia Lavia, Andrea Brancale, Ilaria Granata, Antonio Coluccia, Giuseppe La Regina, Amalia Porta, Ettore Novellino, Marisa Mariani

المساهمون: La Regina, G., Bai, R., Rensen, W., Coluccia, A., Piscitelli, F., Gatti, V., Bolognesi, A., Lavecchia, Antonio, Granata, I., Porta, A., Maresca, B., Soriani, A., Iannitto, M. L., Mariani, M., Santoni, A., Brancale, A., Ferlini, C., Dondio, G., Varasi, M., Mercurio, C., Hamel, E., Lavia, P., Novellino, Ettore, Silvestri, R.

المصدر: Journal of medicinal chemistry 54 (2011): 8394–8406. doi:10.1021/jm2012886
info:cnr-pdr/source/autori:La Regina G, Bai R, Rensen W, Coluccia A, Piscitelli F, Gatti V, Bolognesi A, Lavecchia A, Granata I, Porta A, Maresca B, Soriani A, Iannitto ML, Mariani M, Santoni A, Brancale A, Ferlini C, Dondio MG, Varasi M, Mercurio C, Hamel E, Lavia P, Novellino E, Silvestri R./titolo:Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability/doi:10.1021%2Fjm2012886/rivista:Journal of medicinal chemistry/anno:2011/pagina_da:8394/pagina_a:8406/intervallo_pagine:8394–8406/volume:54

مصطلحات موضوعية: Male, Indoles, Administration, Oral, Pharmacology, Docking, Mice, chemistry.chemical_compound, Drug Discovery, Caspase 3, Cell Cycle, Tubulin Modulators, Vinblastine, Paclitaxel, Biochemistry, Injections, Intravenous, Microsomes, Liver, Molecular Medicine, Cancer Cell, medicine.drug, Biological Availability, Mice, Nude, Antineoplastic Agents, Microtubule, Thiophenes, In Vitro Techniques, Article, Cell Line, Anticancer Agent, Structure-Activity Relationship, Pharmacokinetics, Cell Line, Tumor, Breast Cancer, medicine, Animals, Humans, Pyrroles, Furans, Cell Proliferation, Combretastatin, Cell growth, Antimitotic Drug, Bioavailability, Solubility, chemistry, Drug Resistance, Neoplasm, Apoptosis, Cell culture, Indole, Drug Design, Drug Screening Assays, Antitumor, Colchicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982e1c6a1e422676ace27810974272c2Test
http://hdl.handle.net/11588/415081Test