المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/dataset/PANTHER_/15024486Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.s004Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/dataset/PANTHER_unique_/15024489Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.s005Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/dataset/Metabolon_LCFA_/15024495Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.s007Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/figure/LCFA_Box_plots_/15024516Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.g006Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/figure/Suggested_role_of_CD36_in_Down_syndrome_/15024525Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.g009Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/figure/Plot_of_log_2_values_crGART_HeLa_DEG_fold_change_/15024507Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.g003Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/figure/De_novo_purine_synthesis_DNPS_pathway_/15024501Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.g001Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/figure/crGART_requires_adenine_for_growth_/15024504Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.g002Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/figure/Principal_component_analysis_of_crGART_and_HeLa_replicates_/15024510Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.g004Test

المؤلفون: Randall C. Mazzarino (11160654), Veronika Baresova (5571200), Marie Zikánová (6065822), Nathan Duval (5722925), Terry G. Wilkinson II (11160657), David Patterson (188114), Guido N. Vacano (5722928)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Biotechnology, Developmental Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transcriptome changes, DNPS pathway intermediates, crGART, cell line, CRISPR-Cas 9 mutagenesis, log 2 value, purine synthesis deficiency, phosphoribosylglycinamide formyltra., EC, glycineamide ribonucleotide, purine-depleted growth conditions, novel cell model, HeLa transcriptomes, Alzheimer disease, basal expression, GART activity, CD 36 expression, HeLa cell line, synthetase, trifunctional protein

العلاقة: https://figshare.com/articles/dataset/PANTHER_common_/15024492Test

الإتاحة: https://doi.org/10.1371/journal.pone.0247227.s006Test