المؤلفون: Chin Wong, Thomas Gelzleichter, Junichiro Sonoda, Amos Baruch, Linda Morrow, Suresh Dheerendra, Leslie W. Chinn, Richard Boismenu, Eric Wakshull, Maria E. Wilson, Puneet S. Arora, Shan Chen, Anjali Vaze, Johnny Gutierrez, Nicholas Lewin-Koh

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Male, 0301 basic medicine, obesity, Medical Sciences, FGF21, Adipose tissue, Mice, 0302 clinical medicine, Weight loss, Homeostasis, Medicine, Multidisciplinary, biology, Middle Aged, Biological Sciences, Adipose Tissue, Female, Adiponectin, Antibody, medicine.symptom, FGF21 receptor activation, Adult, Agonist, medicine.medical_specialty, Adolescent, medicine.drug_class, 030209 endocrinology & metabolism, Antibodies, Food Preferences, Young Adult, 03 medical and health sciences, Internal medicine, Weight Loss, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 1, Aged, business.industry, Fibroblast growth factor receptor 1, Body Weight, medicine.disease, Obesity, Fibroblast Growth Factors, stomatognathic diseases, Macaca fascicularis, 030104 developmental biology, Endocrinology, biology.protein, food preference, business, metabolism, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb1e6fc5999a3fd66bc3ad16e368b18Test
https://doi.org/10.1073/pnas.2012073117Test

المؤلفون: Martin O'Rourke, Nicholas Charles Ray, Thomas Gelzleichter, Leah Schutt, Ellen Ingalla, Neville James Mclean, Xiaojing Wang, Stephen Daly, Yingqing Ran, Jiangpeng Liao, Tommy Lai, Yu Zhong, Jun Liang, Sharada Labadie, Lori Friedman, Amy Sambrone, Jun Li, Robert A. Blake, Tao Wang, Liu Zhiguo, Birong Zhang, Steven J. Hartman, Jae H. Chang, Wei Zhou, Jane Guan, Vidhi Mody, Jonathan White, Fabien Roussel, Antonio G. DiPasquale, Jason R. Zbieg, Daniel F. Ortwine, Amy Young, James R. Kiefer, Maia Vinogradova, Simon Charles Goodacre, Deepak Sampath, Tracy Kleinheinz, Xiaoping Zheng, Jennifer M. Giltnane, Lorn Kategaya, Ingrid E. Wertz, Matthew Gill, Ciara Metcalfe, Siew Kuen Yeap, John S. Wai, Jason Oeh, Michelle Nannini

المصدر: Journal of medicinal chemistry. 64(16)

مصطلحات موضوعية: Phases of clinical research, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Mice, Structure-Activity Relationship, Breast cancer, Dogs, In vivo, Drug Discovery, medicine, Animals, Humans, Dosing, Molecular Structure, Chemistry, Antagonist, Estrogen Receptor alpha, medicine.disease, Xenograft Model Antitumor Assays, In vitro, Rats, Macaca fascicularis, Cell culture, Cancer research, MCF-7 Cells, Molecular Medicine, Female, Estrogen Receptor Antagonists, Carbolines

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee86fe3f8068fbb2ff9647a59eadb710Test
https://pubmed.ncbi.nlm.nih.gov/34251202Test

المؤلفون: Kyra J. Cowan, Feng Yang, Mark Z. Chen, Ambrose Williams, Terry Hudson, Shannon Liu, Nicole Valle, Timothy Tully, Junichiro Sonoda, Thomas Gelzleichter, Sharmila Rajan, Frank Macchi

المصدر: Journal of pharmacological and toxicological methods. 94(Pt 1)

مصطلحات موضوعية: 0301 basic medicine, Male, Bispecific antibody, Receptor complex, Mice, Obese, CHO Cells, Toxicology, Antibodies, Cell Line, 03 medical and health sciences, Mice, Cricetulus, Animals, Humans, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Related impurities, Obese Mice, Pharmacology, Manufacturing process, Chemistry, Membrane Proteins, Highly selective, Combinatorial chemistry, Mice, Inbred C57BL, Molecular Weight, stomatognathic diseases, Disease Models, Animal, Drug Combinations, 030104 developmental biology, HEK293 Cells, Product (mathematics), Immunoglobulin G, Drug product, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b66987db00744fc1e7acdc79bb85f9Test
https://pubmed.ncbi.nlm.nih.gov/29660397Test

المؤلفون: Suhasini Iyer, Sherry Yeh, Kathy Howell, Mercedesz Balazs, Laura DeForge, Jeffrey Thompson, Allen J. Ebens, Zhonghua Lin, Christine Ambrose, Maya Leabman, Germaine Fuh, Shiming Ye, Wyne P. Lee, Qinglin Ou, Thomas Gelzleichter, Chingwei V. Lee, Wei Yu Lin, Dimitry M. Danilenko, Melissa A. Starovasnik, Joseph Beyer, Qian Gong, Dhaya Seshasayee, Flavius Martin, Jean Shu, Eric Suto

المصدر: Blood. 110:3959-3967

مصطلحات موضوعية: Cell Survival, medicine.drug_class, medicine.medical_treatment, Plasma Cells, Immunology, Bone Marrow Cells, Monoclonal antibody, Biochemistry, Lymphocyte Depletion, Mice, Species Specificity, Antigen, Neoplasms, B-Cell Activating Factor, Animals, Medicine, B-cell activating factor, B cell, CD20, Mice, Inbred BALB C, biology, business.industry, Antibodies, Monoclonal, Cell Biology, Hematology, Immunotherapy, Blockade, Macaca fascicularis, medicine.anatomical_structure, Immune System Diseases, biology.protein, Antibody, business, B-Cell Activation Factor Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097d141204a369c61e0bbe2e44212d6aTest
https://doi.org/10.1182/blood-2007-04-088088Test

المؤلفون: Eric Stefanich, Deborah L. Mortensen, Wendy S. Putnam, Kristin Wallace, Saloumeh Kadkhodayan-Fischer, Paul J. Fielder, Thomas Gelzleichter, Jenny Jiang, Saileta Prabhu, Dana L. Baker, Suhasini Iyer

مصطلحات موضوعية: medicine.drug_class, Metabolic Clearance Rate, Immunology, Antibody Affinity, Omalizumab, Antigen-Antibody Complex, Receptors, Fc, Pharmacology, Immunoglobulin E, Monoclonal antibody, Antibodies, Monoclonal, Humanized, Mice, Pharmacokinetics, Report, medicine, Immunology and Allergy, Animals, Humans, Receptor, biology, Antibodies, Monoclonal, Haplorhini, Fragment crystallizable region, Asthma, Antibodies, Anti-Idiotypic, Pharmacodynamics, biology.protein, Antibody, medicine.drug, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ca34912b3cf9479a187310d4a2e2e6Test
https://europepmc.org/articles/PMC3502239Test/

المؤلفون: Sean K, Kelley, Thomas, Gelzleichter, Dong, Xie, Wyne P, Lee, Walter C, Darbonne, Ferhan, Qureshi, Kim, Kissler, Ezogelin, Oflazoglu, Iqbal S, Grewal

المصدر: British journal of pharmacology. 148(8)

مصطلحات موضوعية: Male, Macaca fascicularis, Mice, Species Specificity, Papers, otorhinolaryngologic diseases, Animals, Antibodies, Monoclonal, Enzyme-Linked Immunosorbent Assay, sense organs, Mice, SCID, CD40 Antigens, Flow Cytometry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::37d0f3daf2f60e1632a9ff1fc6edb7a7Test
https://pubmed.ncbi.nlm.nih.gov/16847437Test