نتائج البحث

1

Systems biology strategy and experimental validation to uncover the pharmacological mechanism of Xihuang Pill in treating non-small cell lung cancer

المؤلفون: Zhenjie Zhuang, Dan Huang, Zhou Rui Sheng, Zeng Jie Ye, Haimei Jiang, Yi Yuan, Binyu Qin, Yan Zhao, Hua-Feng Pan, Ying Tang

المصدر: Phytomedicine. 108:154491

مصطلحات موضوعية: Pharmacology, Lung Neoplasms, Systems Biology, Mice, Nude, Pharmaceutical Science, Gene Expression Regulation, Neoplastic, Mice, Complementary and alternative medicine, Carcinoma, Non-Small-Cell Lung, Drug Discovery, Tumor Microenvironment, Animals, Humans, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8128c0cd99260768d7a67e9e4a3e5c2cTest
https://doi.org/10.1016/j.phymed.2022.154491Test

2

Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension

المساهمون: British Heart Foundation

المصدر: American Journal of Respiratory and Critical Care Medicine

مصطلحات موضوعية: Respiratory System, Complement Pathway, Alternative, Critical Care and Intensive Care Medicine, Mice, 0302 clinical medicine, Medicine, 030212 general & internal medicine, Complement Activation, 11 Medical and Health Sciences, Mice, Knockout, Pulmonary Arterial Hypertension, biology, Complement C5, Complement C3, Prognosis, MACROPHAGE RECRUITMENT, 3. Good health, Hypertension, Biomarker (medicine), medicine.symptom, Antibody, Life Sciences & Biomedicine, Complement Factor B, EXPRESSION, Pulmonary and Respiratory Medicine, FIBROBLASTS, vascular remodeling, Hypertension, Pulmonary, IMMUNE, Immunoglobulins, Inflammation, ALTERNATIVE PATHWAY, Proinflammatory cytokine, 03 medical and health sciences, Critical Care Medicine, General & Internal Medicine, Animals, Humans, Pulmonary Vascular Disease, Science & Technology, IGG, business.industry, hypoxia, Granulocyte-Macrophage Colony-Stimulating Factor, biomarkers, AMPLIFICATION, GM-CSF, Original Articles, Hypoxia (medical), medicine.disease, Pulmonary hypertension, Rats, Complement system, Disease Models, Animal, 030228 respiratory system, inflammation, Immunoglobulin G, Immunology, biology.protein, Alternative complement pathway, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae262e1e465000c232d4aacd14e460c6Test
http://europepmc.org/articles/PMC6961733Test

3

NEDD9 Is a Novel and Modifiable Mediator of Platelet–Endothelial Adhesion in the Pulmonary Circulation

المصدر: Am J Respir Crit Care Med
American Journal of Respiratory and Critical Care Medicine

مصطلحات موضوعية: Blood Platelets, Male, Pulmonary and Respiratory Medicine, Pulmonary Circulation, Hypertension, Pulmonary, Cell Communication, Critical Care and Intensive Care Medicine, NEDD9, Mice, 03 medical and health sciences, 0302 clinical medicine, Mediator, Cell Adhesion, medicine, Animals, Humans, Platelet, 030212 general & internal medicine, Endothelium, Hypoxia, Cells, Cultured, Adaptor Proteins, Signal Transducing, business.industry, Editorials, Endothelial Cells, Adhesion, Original Articles, Middle Aged, Hypoxia (medical), medicine.disease, Thrombosis, 030228 respiratory system, Models, Animal, Cancer research, Female, medicine.symptom, Pulmonary Embolism, business, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191e4218f50b4e0e706507034153a2beTest
https://europepmc.org/articles/PMC8483217Test/

4

Effect of Moringa oleifera stem extract on hydrogen peroxide-induced opacity of cultured mouse lens

المؤلفون: Ma-li Zheng, Yu Zhou, Rui-sheng Zhong, Xin Jin, Lei Qi, Weijie Li, Yuan Lin

المصدر: BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Complementary and Alternative Medicine

مصطلحات موضوعية: Male, Antioxidant, medicine.medical_treatment, medicine.disease_cause, Cataract, Superoxide dismutase, Moringa, Organ culture, 03 medical and health sciences, chemistry.chemical_compound, Mice, Lens, 0302 clinical medicine, Lens, Crystalline, medicine, Animals, Humans, PPAR alpha, Hydrogen peroxide, chemistry.chemical_classification, Moringa oleifera, Reactive oxygen species, Mice, Inbred BALB C, biology, Plant Extracts, Superoxide Dismutase, General Medicine, Glutathione, Hydrogen Peroxide, lcsh:Other systems of medicine, Catalase, lcsh:RZ201-999, Molecular biology, 030205 complementary & alternative medicine, Complementary and alternative medicine, chemistry, Oxidative stress, 030220 oncology & carcinogenesis, biology.protein, Reactive Oxygen Species, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba94a3b3226e3b153957a7760b87355Test
http://link.springer.com/article/10.1186/s12906-019-2555-zTest

5

Antiviral Effects of ABMA and DABMA against Influenza Virus In Vitro and In Vivo via Regulating the Endolysosomal Pathway and Autophagy

المؤلفون: Hongtao Liu, Chunlai Jiang, Yu Wu, Min Wu, Jiaxin Wu, Guanshu Zhao, Jie Sun, Xinyu Huang, Jiemin Li, Rui Sheng, Julien Barbier, Jean-Christophe Cintrat, Daniel Gillet, Weiheng Su

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3940

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3d2b20a986e22452495cfdac4e40abTest
https://doi.org/10.3390/ijms23073940Test

6

Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis

المؤلفون: Yu Liang, Mengyuan Wang, Qiuchan Xiong, Ling Ye, Qianming Chen, Jing Li, Yuchen Guo, Shuibin Lin, Yuan Wang, Liang Xie, Rixin Zheng, Quan Yuan, Xuedong Zhou, Peng Deng, Yi-Zhou Jiang, Yunshu Wu, Rui Sheng

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Adenosine, Science, General Physics and Astronomy, Parathyroid hormone, Bone Marrow Cells, Biology, Methylation, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, Bone Marrow, Osteogenesis, Conditional gene knockout, medicine, Animals, Epigenetics, RNA, Messenger, lcsh:Science, Adiposity, Receptor, Parathyroid Hormone, Type 1, Regulation of gene expression, Mice, Knockout, Multidisciplinary, Adipogenesis, Mesenchymal stem cell, Cell Differentiation, Estrogens, Mesenchymal Stem Cells, General Chemistry, Methyltransferases, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Parathyroid Hormone, Osteoporosis, lcsh:Q, Bone marrow, Signal transduction, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a675f4088bddf5e6eeff638b3e85a9Test
https://doaj.org/article/6dee164452b4421384ea332c5f24434fTest

7

Maternal anesthesia with sevoflurane during the mid-gestation induces social interaction deficits in offspring C57BL/6 mice

المؤلفون: Jianping Yang, Fu-hai Ji, Qingcai Chen, Xin Jin, Shaoyong Song, Wei Chu, Rui Sheng

المصدر: Biochemical and biophysical research communications. 553

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5269af2a6df6508944f83d74c947d7Test
https://pubmed.ncbi.nlm.nih.gov/33756347Test

8

NADPH is superior to NADH or edaravone in ameliorating metabolic disturbance and brain injury in ischemic stroke

المؤلفون: Zheng-Hong Qin, Zhong Chen, Mei Li, Rui Sheng, Rong Zhang, Jun-Chao Wu, Xin-Xin Wang, Guang-Hui Mao, Jing She, Fan Wang, Rong Han

المصدر: Acta Pharmacol Sin

مصطلحات موضوعية: 0301 basic medicine, Male, Antioxidant, medicine.medical_treatment, Pharmacology, Nicotinamide adenine dinucleotide, medicine.disease_cause, Neuroprotection, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, Random Allocation, 0302 clinical medicine, Atrophy, Stress, Physiological, Edaravone, medicine, Animals, Pharmacology (medical), Ischemic Stroke, Mice, Inbred ICR, Dose-Response Relationship, Drug, business.industry, Infarction, Middle Cerebral Artery, General Medicine, medicine.disease, NAD, In vitro, Disease Models, Animal, 030104 developmental biology, Neuroprotective Agents, chemistry, 030220 oncology & carcinogenesis, Reperfusion Injury, Ischemic stroke, business, Oxidative stress, NADP

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c62e59f3695a1b6f002bbaca1faa03Test
https://pubmed.ncbi.nlm.nih.gov/34168317Test

9

A sphingosine kinase 2-mimicking TAT-peptide protects neurons against ischemia-reperfusion injury by activating BNIP3-mediated mitophagy

المؤلفون: Yun-Fei Xia, Zheng-Hong Qin, Lei Chen, Ke Qian, Xin-Xin Wang, Rui Sheng, Christian Waeber, Jia-Li Chen, Jie Tang

مصطلحات موضوعية: Male, 0301 basic medicine, Small interfering RNA, BNIP3, medicine.medical_treatment, Intraperitoneal injection, Ischemia, Brain Edema, Pharmacology, Neuroprotection, Mitochondrial Proteins, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Mitophagy, Autophagy, Animals, Medicine, Sphingosine kinase 2, RNA, Small Interfering, Ischemic Stroke, Neurons, Mice, Inbred ICR, business.industry, TAT-SPK2 peptide, Membrane Proteins, Sphingosine Kinase 2, Infarction, Middle Cerebral Artery, Cerebral ischemia, medicine.disease, Mitochondria, Phosphotransferases (Alcohol Group Acceptor), Neuroprotective Agents, 030104 developmental biology, Proto-Oncogene Proteins c-bcl-2, Reperfusion Injury, Gene Products, tat, Beclin-1, Peptides, business, Reperfusion injury, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f413142c7107a7306ffaae2c8c92766cTest
https://hdl.handle.net/10468/10657Test

10

AFF1 inhibits adipogenic differentiation via targeting TGM2 transcription

المؤلفون: Yunshu Wu, Quan Yuan, Yuan Wang, Ruoshi Xu, Weimin Lin, Y. Chen, Rui Sheng, Chenchen Zhou

المصدر: Cell Proliferation

مصطلحات موضوعية: 0301 basic medicine, 3T3‐L1 pre‐adipocytes, Small interfering RNA, Stromal cell, Transcription, Genetic, Mice, Nude, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Transcription (biology), GTP-Binding Proteins, AF4/FMR2 family member 1, 3T3-L1 Cells, Oil Red O, Animals, Humans, Protein Glutamine gamma Glutamyltransferase 2, Cells, Cultured, Mice, Inbred BALB C, Adipogenesis, Transglutaminases, human mesenchymal stromal/stem cells, Stem Cells, Mesenchymal stem cell, Nuclear Proteins, Promoter, Mesenchymal Stem Cells, Cell Biology, General Medicine, Original Articles, Cell biology, DNA-Binding Proteins, 030104 developmental biology, chemistry, Gene Expression Regulation, 030220 oncology & carcinogenesis, TGM2, Original Article, Stem cell, Transcriptional Elongation Factors, adipogenic differentiation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e1d61a256d8b185af9ab13708517e9Test
http://europepmc.org/articles/PMC7309944Test

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