نتائج البحث - "Kaye J. Williams"

1

A preclinical radiotherapy dosimetry audit using a realistic 3D printed murine phantom

المؤلفون: Emma R, Biglin, Adam H, Aitkenhead, Gareth J, Price, Amy L, Chadwick, Elham, Santina, Kaye J, Williams, Karen J, Kirkby

المصدر: Scientific reports. 12(1)

مصطلحات موضوعية: Mice, Alanine, Phantoms, Imaging, Printing, Three-Dimensional, Animals, Reproducibility of Results, Radiometry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::8e595d1b327ffaf9c6252dd6fcbf3b30Test
https://pubmed.ncbi.nlm.nih.gov/35474242Test

2

Preclinical dosimetry: exploring the use of small animal phantoms

المؤلفون: Amy L. Chadwick, Gareth J Price, Kaye J. Williams, Emma R. Biglin, A. Aitkenhead, Karen J. Kirkby

المصدر: Radiation Oncology, Vol 14, Iss 1, Pp 1-10 (2019)
Radiation Oncology (London, England)
Biglin, E R, Price, G J, Chadwick, A L, Aitkenhead, A H, Williams, K J & Kirkby, K J 2019, ' Preclinical dosimetry: exploring the use of small animal phantoms ', Radiation Oncology, vol. 14, no. 1 . https://doi.org/10.1186/s13014-019-1343-8Test

مصطلحات موضوعية: Tissue-equivalent, lcsh:Medical physics. Medical radiology. Nuclear medicine, medicine.medical_specialty, Standardization, lcsh:R895-920, Dose profile, Review, lcsh:RC254-282, Phantoms, 03 medical and health sciences, Mice, 0302 clinical medicine, Small animal, Dosimetry, medicine, Animals, Humans, Radiology, Nuclear Medicine and imaging, Medical physics, Manchester Cancer Research Centre, Radiotherapy, business.industry, Phantoms, Imaging, ResearchInstitutes_Networks_Beacons/mcrc, Radiotherapy Planning, Computer-Assisted, Radiotherapy Dosage, Equipment Design, 3D printing, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, Tissue equivalent, Oncology, 030220 oncology & carcinogenesis, Printing, Three-Dimensional, business, Quality assurance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4db655234c58206fba345e933cb1c6cTest
http://link.springer.com/article/10.1186/s13014-019-1343-8Test

3

3D DESI-MS lipid imaging in a xenograft model of glioblastoma: a proof of principle

المؤلفون: Emmy Hoyes, Emmanuelle Claude, Kaye J. Williams, Joanna Denbigh, Lidan Christie, Adam McMahon, Fiona Henderson, Emrys A. Jones, Richard Chapman, Federico Roncaroli

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Henderson, F, Jones, E, Denbigh, J, Christie, L, Chapman, R, Hoyes, E, Claude, E, Williams, K, Roncaroli, F & McMahon, A 2020, ' 3D DESI-MS lipid imaging in a xenograft model of glioblastoma: a proof of principle ', Scientific Reports, vol. 10, 16512 (2020) . https://doi.org/10.1038/s41598-020-73518-xTest

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643732f3e557b2fbd565a94d6d1d87f6Test
https://doi.org/10.1038/s41598-020-73518-xTest

4

Cardiac sub-volume targeting demonstrates regional radiosensitivity in the mouse heart

المؤلفون: Eleanor K Gill, Stephen J. McMahon, David J. Grieve, Kevin S Edgar, Carmen Bergom, Mihaela Ghita, Marianne C. Aznar, Kaye J. Williams, Chris J Watson, Karl T. Butterworth, Alan McWilliam, Eliana Vasquez Osorio, Marcel van Herk, Gerard Walls

المصدر: Radiother Oncol
Ghita, M, Gill, E, Walls, G, Edgar, K, McMahon, S, Vasquez Osorio, E, Bergom, C, Grieve, D, Watson, C, McWilliam, A, Aznar, M, van herk, M, Williams, K J & Butterworth, K 2020, ' Cardiac sub-volume targeting demonstrates regional radiosensitivity in the mouse heart ', Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology . https://doi.org/10.1016Test/j.radonc.2020.07.016, https://doi.org/10.1016Test/j.radonc.2020.07.016
Ghita, M, Gill, E K, Walls, G M, Edgar, K S, McMahon, S J, Osorio, E V, Bergom, C, Grieve, D J, Watson, C J, McWilliam, A, Aznar, M, van Herk, M, Williams, K J & Butterworth, K T 2020, ' Cardiac sub-volume targeting demonstrates regional radiosensitivity in the mouse heart ', Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology . https://doi.org/10.1016Test/j.radonc.2020.07.016

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Diastole, Radiation Tolerance, Small animal radiotherapy, Article, 030218 nuclear medicine & medical imaging, Mouse model, 03 medical and health sciences, Mice, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Cardiac toxicity, Internal medicine, medicine, Preclinical radiotherapy, Animals, Humans, Radiology, Nuclear Medicine and imaging, Radiosensitivity, Lung cancer, Radiation Injuries, Radiometry, Mouse Heart, Cone beam ct, business.industry, Radiotherapy Planning, Computer-Assisted, Heart, Radiotherapy Dosage, Hematology, medicine.disease, Apex (geometry), Radiation therapy, Mice, Inbred C57BL, Oncology, Radiology Nuclear Medicine and imaging, 030220 oncology & carcinogenesis, Cardiology, business, Heart dose

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d93aad34ccb05f8d99f62504315232eTest
https://europepmc.org/articles/PMC10181791Test/

5

Tubulin-binding dibenz[c,e]oxepines: Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents

المؤلفون: Timothy W. Wallace, John A. Hadfield, Steven B. Rossington, Kaye J. Williams, Steven D. Shnyder

المصدر: Rossington, S, Hadfield, J, Shnyder, S D, Wallace, T & Williams, K 2017, ' Tubulin-binding dibenz[c,e]oxepines : Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents ', Bioorganic and Medicinal Chemistry, vol. 25, no. 5, pp. 1630-1642 . https://doi.org/10.1016Test/j.bmc.2017.01.027

مصطلحات موضوعية: Necrosis, Clinical Biochemistry, Pharmaceutical Science, Tumour vasculature, 01 natural sciences, Biochemistry, Tubulin binding, Structural variation, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tubulin, Cell Line, Tumor, Neoplasms, Biological property, Drug Discovery, Journal Article, medicine, Animals, Humans, Colchicine, Molecular Biology, Biological evaluation, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, direct arylation, Organic Chemistry, palladium catalyst, 0104 chemical sciences, tubulin, chemistry, Cell culture, 030220 oncology & carcinogenesis, biology.protein, Heterografts, Molecular Medicine, medicine.symptom, Dibenzoxepins

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7159b0428917a521e7ecb361504f199Test
https://doi.org/10.1016Test/j.bmc.2017.01.027

6

Non-myeloablative busulfan chimeric mouse models are less pro-inflammatory than head-shielded irradiation for studying immune cell interactions in brain tumours

المؤلفون: Gabriella Forte, Brian A. Telfer, Ian Kamaly-Asl, Aiyin Liao, Claire O'Leary, Helen Parker, Brian W. Bigger, Kaye J. Williams, A. Saam Youshani, Samuel Rowlston

المصدر: Journal of Neuroinflammation
Youshani, A S, Rowlston, S, O'Leary, C, Forte, G, Parker, H, Liao, A, Telfer, B, Williams, K, Kamaly-Asl, I D & Bigger, B W 2019, ' Non-myeloablative busulfan chimeric mouse models are less pro-inflammatory than head-shielded irradiation for studying immune cell interactions in brain tumours ', Journal of Neuroinflammation, vol. 16, no. 1, 25 . https://doi.org/10.1186/s12974-019-1410-yTest
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)

مصطلحات موضوعية: 0301 basic medicine, Lydia Becker Institute, medicine.medical_treatment, lcsh:RC346-429, Mice, 0302 clinical medicine, Immunity, Cellular, Brain Neoplasms, General Neuroscience, Haematopoiesis, Cytokine, medicine.anatomical_structure, Neurology, Radiation Chimera, Cytokines, Female, Microglia, Chimeric mouse model, medicine.drug, Immunology, Bone Marrow Cells, 03 medical and health sciences, Cellular and Molecular Neuroscience, Immune system, Antigen, ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation, Cell Line, Tumor, medicine, Animals, Head-shielded irradiation, Antineoplastic Agents, Alkylating, Busulfan, Neuroinflammation, lcsh:Neurology. Diseases of the nervous system, Inflammation, business.industry, Chimera, Research, Macrophages, Non-myeloablative conditioning, Mice, Inbred C57BL, 030104 developmental biology, Cancer research, Leukocyte Common Antigens, Bone marrow, business, Glioblastoma, 030217 neurology & neurosurgery, Whole Bone Marrow, Neoplasm Transplantation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34af8a6d27ae53e8d5199c4dd9f7f6dTest
http://europepmc.org/articles/PMC6362590Test

7

Oxygen-enhanced MRI Is Feasible, Repeatable, and Detects Radiotherapy-induced Change in Hypoxia in Xenograft Models and in Patients with Non-small Cell Lung Cancer

المصدر: Salem, A, Little, R A, Latif, A, Featherstone, A K, Babur, M, Peset, I, Cheung, S, Watson, Y, Tessyman, V, Mistry, H, Ashton, G, Behan, C, Matthews, J C, Asselin, M-C, Bristow, R G, Jackson, A, Parker, G J M, Faivre-Finn, C, Williams, K J & O'Connor, J P B 2019, ' Oxygen-enhanced MRI Is Feasible, Repeatable, and Detects Radiotherapy-induced Change in Hypoxia in Xenograft Models and in Patients with Non-small Cell Lung Cancer ', Clinical Cancer Research, vol. 25, no. 13, pp. 3818-3829 . https://doi.org/10.1158/1078-0432.CCR-18-3932Test

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Mice, 0302 clinical medicine, Internal medicine, Glioma, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, medicine, Animals, Humans, Precision Medicine, Lung cancer, Hypoxia, Tumor hypoxia, medicine.diagnostic_test, Manchester Cancer Research Centre, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, Reproducibility of Results, Magnetic resonance imaging, Hypoxia (medical), medicine.disease, Image Enhancement, Magnetic Resonance Imaging, Xenograft Model Antitumor Assays, Tumor Burden, Radiation therapy, Oxygen, Disease Models, Animal, Regional Blood Flow, 030220 oncology & carcinogenesis, medicine.symptom, business, Ex vivo, Chemoradiotherapy, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1346c3b72db2126441d823a34d7edaTest
https://pubmed.ncbi.nlm.nih.gov/31053599Test

8

Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters

المؤلفون: Manal Mehibel, Fernando Ortiz-Martinez, Catharine M L West, Nadine Voelxen, Brian A. Telfer, Amy Boyers, Ian J. Stratford, Kaye J. Williams, Susan E. Critchlow, Wolfgang Mueller-Klieser, Amy L. Chadwick

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Mehibel, M, Ortiz-martinez, F, Voelxen, N, Boyers, A, Chadwick, A, Telfer, B A, Mueller-klieser, W, West, C M, Critchlow, S E, Williams, K J & Stratford, I J 2018, ' Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters ', Scientific Reports, vol. 8, no. 1, 16804 . https://doi.org/10.1038/s41598-018-35103-1Test

مصطلحات موضوعية: Monocarboxylic Acid Transporters, 0301 basic medicine, Statin, medicine.drug_class, lcsh:Medicine, Pyrimidinones, Thiophenes, Article, Oxidative Phosphorylation, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Lactic Acid, Precision Medicine, lcsh:Science, Multidisciplinary, Manchester Cancer Research Centre, biology, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, lcsh:R, Head and neck cancer, Cancer, Prognosis, medicine.disease, Head and neck squamous-cell carcinoma, 030104 developmental biology, Monocarboxylate transporter 1, Head and Neck Neoplasms, Simvastatin, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Cancer research, Biomarker (medicine), lcsh:Q, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, Biomarkers, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d742e81eac83a56f7780095c7b65244Test
https://doi.org/10.1038/s41598-018-35103-1Test

9

High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma

المؤلفون: Joanna Dutko-Gwozdz, Omar N. Pathmanaban, Peter Cueppens, Kenny Yu, Brian A. Telfer, Gareth Griffiths, Ian Peers, Roderick Benson, Kaye J. Williams, Brian W. Bigger, Deniz Beyit, Catherine McBain, Ian Kamaly-Asl, Amir Saam Youshani, Jessica T. Taylor

المصدر: PLoS ONE
Yu, K K H, Taylor, J T, Pathmanaban, O N, Youshani, A S, Beyit, D, Dutko-Gwozdz, J, Benson, R, Griffiths, G, Peers, I, Cueppens, P, Telfer, B A, Williams, K J, McBain, C, Kamaly-Asl, I D & Bigger, B W 2018, ' High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma ', PLoS ONE, vol. 13, no. 3, e0193694 . https://doi.org/10.1371/journal.pone.0193694Test
PLoS ONE, Vol 13, Iss 3, p e0193694 (2018)

مصطلحات موضوعية: 0301 basic medicine, Cancer Treatment, lcsh:Medicine, Apoptosis, Mice, SCID, Bortezomib, Mice, 0302 clinical medicine, Mice, Inbred NOD, Medicine and Health Sciences, Tumor Cells, Cultured, Medicine, Blastomas, lcsh:Science, Neurological Tumors, Staining, Multidisciplinary, Cell Death, Brain Neoplasms, Cell Staining, Oncology, Neurology, Cell Processes, 030220 oncology & carcinogenesis, High-content screening, Neoplastic Stem Cells, Female, Biological Cultures, medicine.drug, Research Article, Transplantation, Heterologous, Surgical and Invasive Medical Procedures, Antineoplastic Agents, Research and Analysis Methods, 03 medical and health sciences, In vivo, Cancer stem cell, Neurosphere, Animals, Humans, Cell Proliferation, Pharmacology, Mitoxantrone, Drug Screening, Surgical Resection, business.industry, lcsh:R, Biology and Life Sciences, Cancers and Neoplasms, Cell Biology, Cell Cultures, Transplantation, Nuclear Staining, 030104 developmental biology, Cell culture, Specimen Preparation and Treatment, Drug Resistance, Neoplasm, Gamma Rays, Cancer research, lcsh:Q, Neurospheres, business, Glioblastoma, Glioblastoma Multiforme

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62738a9c8f7a45480d33d24e41cc123dTest
http://europepmc.org/articles/PMC5834163Test

10

Dissemination via the lymphatic or angiogenic route impacts the pathology, microenvironment and hypoxia-related drug response of lung metastases

المؤلفون: Muhammad Babur, Brian A. Telfer, R J Fitzmaurice, Roben G. Gieling, Kaye J. Williams

المصدر: Clinical & Experimental Metastasis. 32:567-577

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389a1ef6e7a7d55e258395f2bf69d029Test
https://doi.org/10.1007/s10585-015-9728-zTest

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