المؤلفون: Chang, Wakam, Wang, Yuexia, Östlund, Cecilia, Worman, Howard, Gundersen, Gregg, Luxton, Gw

المصدر: Proceedings of the National Academy of Sciences of USA. 116(9)

مصطلحات موضوعية: Hutchinson–Gilford progeria syndrome, LINC complex, SUN proteins, centrosome orientation, nuclear movement, Aging, Animals, Cell Nucleus, Cell Polarity, Dyneins, Fibroblasts, Gene Expression Regulation, Humans, Lamin Type A, Membrane Proteins, Mice, Microfilament Proteins, Microtubule-Associated Proteins, NIH 3T3 Cells, Nerve Tissue Proteins, Nuclear Envelope, Nuclear Proteins, Progeria, Protein Prenylation

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/44g669rkTest

المؤلفون: Christina Manakanatas, Santhosh Kumar Ghadge, Azra Agic, Fatih Sarigol, Petra Fichtinger, Irmgard Fischer, Roland Foisner, Selma Osmanagic-Myers

المصدر: Aging (Albany NY)

مصطلحات موضوعية: Aging, integumentary system, Down-Regulation, Aorta, Thoracic, Cell Biology, senescence-associated micro RNAs, Atherosclerosis, Lamin Type A, Hutchinson-Gilford progeria syndrome, Up-Regulation, Mice, MicroRNAs, Progeria, Gene Expression Regulation, cardiovascular disease, endothelial senescence, Paracrine Communication, Animals, Endothelium, Vascular, RNA, Messenger, Tumor Suppressor Protein p53, Cellular Senescence, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164366cc8189269bf555e5916bae4beeTest
http://europepmc.org/articles/PMC8791216Test

المؤلفون: Rivera-Torres, José, Calvo, Conrado J, Llach, Anna, Guzmán-Martínez, Gabriela, Caballero, Ricardo, González-Gómez, Cristina, Jiménez-Borreguero, Luis J, Guadix, Juan A, Osorio, Fernando G, López-Otín, Carlos, Herraiz-Martínez, Adela, Cabello, Nuria, Vallmitjana, Alex, Benítez, Raul, Gordon, Leslie B, Jalife, José, Pérez-Pomares, José M, Tamargo, Juan, Delpón, Eva, Hove-Madsen, Leif, Filgueiras-Rama, David, Andrés, Vicente

مصطلحات موضوعية: Hutchinson–Gilford progeria syndrome, calcium handling, connexin43, prelamin A, progerin, Adolescent, Adult, Animals, Arrhythmias, Cardiac, Calcium, Cardiac Conduction System Disease, Child, Preschool, Connexin 43, Female, Heart, Humans, Male, Membrane Proteins, Metalloendopeptidases, Mice, Inbred C57BL, Knockout, Myocardium, Nuclear Lamina, Progeria, Sarcoplasmic Reticulum, Young Adult

العلاقة: http://hdl.handle.net/10668/10568Test; PMC5135377; https://europepmc.org/articles/pmc5135377?pdf=renderTest; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135377/pdfTest

الإتاحة: https://doi.org/10.1073/pnas.1603754113Test
http://hdl.handle.net/10668/10568Test
https://europepmc.org/articles/pmc5135377?pdf=renderTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135377/pdfTest

المؤلفون: Ricardo Villa-Bellosta

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Male, 0301 basic medicine, 030204 cardiovascular system & hematology, Pyrophosphate, Mice, chemistry.chemical_compound, Adenosine Triphosphate, Progeria, 0302 clinical medicine, Gene Knock-In Techniques, Pyrophosphatases, RNA, Small Interfering, media_common, Multidisciplinary, integumentary system, Apyrase, Longevity, Calcinosis, Biological Sciences, Lamin Type A, Diphosphates, RNA Interference, Hutchinson Gilford Progeria Syndrome, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, media_common.quotation_subject, Myocytes, Smooth Muscle, Aortic Diseases, Mice, Transgenic, Real-Time Polymerase Chain Reaction, 03 medical and health sciences, Antigens, CD, Internal medicine, medicine, Animals, Humans, Vascular calcification, Phosphoric Diester Hydrolases, business.industry, nutritional and metabolic diseases, Alkaline Phosphatase, medicine.disease, Disease Models, Animal, 030104 developmental biology, Endocrinology, Levamisole, chemistry, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc5d2c846386409bed45f6b6a6f47f5Test
https://doi.org/10.1073/pnas.1910972116Test

المؤلفون: Sussan Nourshargh, Loïc Rolas, María J. Andrés-Manzano, Beatriz Dorado, Víctor Fanjul, Ignacio Benedicto, Carla Espinós-Estévez, Pilar Gonzalo, Magda R. Hamczyk, Raquel Riquelme-Borja, Lara Del Campo, Jesús Vázquez, Alvaro Macias, Emilio Camafeita, Amanda Sánchez-López, Cristina González-Gómez, Anna Barkaway, Vicente Andrés

المساهمون: Ministerio de Ciencia e Innovación (España), Agencia Estatal de Investigación (España), Unión Europea. Comisión Europea. H2020, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Asociación Apadrina la Ciencia-Ford España-Ford Motor Company Fund, Fundación La Caixa, Comunidad de Madrid (España), Instituto de Salud Carlos III, Fundación ProCNIC, Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España)

المصدر: Circulation

مصطلحات موضوعية: Premature aging, medicine.medical_specialty, Myocytes, Smooth Muscle, cardiac myocyte, Mice, Transgenic, Disease, Muscle, Smooth, Vascular, smooth muscle, Mice, Progeria, Physiology (medical), Internal medicine, Original Research Articles, medicine, Animals, Humans, Myocytes, Cardiac, Myocardial infarction, Stroke, integumentary system, business.industry, cell, Progerin, medicine.disease, Lamin Type A, Hutchinson-Gilford progeria syndrome, Disease Models, Animal, Heart failure, Cardiology, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Cardiology and Cardiovascular Medicine, business, Lamin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b306bba104ae2c185182e39402ab1beTest
https://pubmed.ncbi.nlm.nih.gov/34694158Test

المؤلفون: Vicente Andrés, Beatriz Dorado, Ignacio Benedicto

المساهمون: Ministerio de Ciencia e Innovación (España), Instituto de Salud Carlos III, Unión Europea. Comisión Europea. H2020, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Progeria Research Foundation, Fundación La Marató TV3, Comunidad de Madrid (España), Fundación ProCNIC

المصدر: Cells
Cells, Vol 10, Iss 1157, p 1157 (2021)

مصطلحات موضوعية: 0301 basic medicine, Aging, Myocardial Infarction, Disease, Review, 030204 cardiovascular system & hematology, Bioinformatics, Cardiovascular System, endothelial dysfunction, Muscle, Smooth, Vascular, Mice, 0302 clinical medicine, Progeria, cardiovascular disease, Myocardial infarction, Biology (General), Endothelial dysfunction, Stroke, Cytoskeleton, Clinical Trials as Topic, integumentary system, General Medicine, Progerin, Lamin Type A, vessel stiffening, Physiological Aging, Phenotype, Cardiovascular Diseases, congenital, hereditary, and neonatal diseases and abnormalities, Heart Diseases, QH301-705.5, extracellular matrix, 03 medical and health sciences, progeroid animal models, medicine, Animals, Humans, Vascular Calcification, Hutchinson-Gilford progeria syndrome (HGPS), business.industry, fibrosis, nutritional and metabolic diseases, Muscle, Smooth, medicine.disease, Atherosclerosis, Fibrosis, Disease Models, Animal, 030104 developmental biology, Heart failure, progerin, Endothelium, Vascular, vascular smooth muscle cell, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c457295db5bc0418addb0cd861a1c7a6Test
http://europepmc.org/articles/PMC8151355Test

المؤلفون: Villa-Bellosta, Ricardo, Rivera-Torres, Jose, Osorio, Fernando G, Acin-Perez, Rebeca, Enriquez, Jose Antonio, López-Otín, Carlos, Andres, Vicente

المساهمون: Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, Progeria Research Foundation, Botín Foundation, Fundación Cajastur, Fundación ProCNIC

مصطلحات موضوعية: ATP, Hutchinson-Gilford progeria syndrome, muscle, Progerin, Pyrophosphate, Tissue-non specific alkaline phosphatase, Vascular calcification, Smooth, Adenosine Triphosphate, Alkaline Phosphatase, Animals, Aorta, Cells, Cultured, Diphosphates, Disease Models, Animal, Lamin Type A, Male, Mice, Inbred C57BL, Mutant Strains, Mitochondria, Vascular, Progeria, Treatment Outcome

العلاقة: Postprint; https://doi.org/10.1161/CIRCULATIONAHA.112.000571Test; info:eu-repo/grantAgreement/ES/SAF2010-16044; info:eu-repo/grantAgreement/ES/RD06/0014/0021; info:eu-repo/grantAgreement/ES/RD12/0042/0028; info:eu-repo/grantAgreement/ES/JCI-2011-09663; Circulation. 2013; 127(24):2442-51; http://hdl.handle.net/20.500.12105/7754Test; Circulation

الإتاحة: https://doi.org/20.500.12105/7754Test
https://doi.org/10.1161/CIRCULATIONAHA.112.000571Test
https://hdl.handle.net/20.500.12105/7754Test

المؤلفون: Jesús Vázquez, Vicente Andrés, José Rivera-Torres, Beatriz Dorado, Cristina González-Gómez, Inmaculada Jorge, Ana Barettino, Alvaro Macias, Emilio Camafeita, María J. Andrés-Manzano, Carlos López-Otín, Víctor Fanjul

المساهمون: Ministerio de Ciencia e Innovación (España), Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Instituto de Salud Carlos III, Fundación La Marató TV3, Fundación La Caixa, Progeria Research Foundation, Fundación ProCNIC, European Regional Development Fund (ERDF/FEDER), Instituto de Salud Carlos III - ISCIII, Fundació La Marató

المصدر: RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Repisalud
Instituto de Salud Carlos III (ISCIII)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
Aging Cell

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Aging, Swine, Enfermedad cardiovascular, Envejecimiento, Biology, Protein oxidation, Bioinformatics, 03 medical and health sciences, Mice, 0302 clinical medicine, Progeria, Glycation, medicine, Animals, Humans, mouse models, Risk factor, pathophysiology, pig models, cardiometabolic disease, Hutchinson–Gilford progeria syndrome, integumentary system, Cell Biology, Original Articles, medicine.disease, Pathophysiology, Disease Models, Animal, 030104 developmental biology, Proteostasis, Cardiovascular Diseases, Heart failure, HGPS, Original Article, 030217 neurology & neurosurgery, Célula

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50b4d1c300dd6743871c47c547e973eTest
http://hdl.handle.net/10651/56245Test

المؤلفون: Daisuke Takahashi, Nanako Machida, Yuto Takahashi, Pavel Hozák, Masahiko Harata, Kei Miyamoto, Junpei Matsushita, Tom Misteli, Shogo Hiratsuka

المصدر: Nucleus, Vol 11, Iss 1, Pp 250-263 (2020)
Nucleus
article-version (VoR) Version of Record

مصطلحات موضوعية: Premature aging, congenital, hereditary, and neonatal diseases and abnormalities, DNA Repair, lcsh:QH426-470, nuclear organization, macromolecular substances, Biology, Mice, 03 medical and health sciences, Progeria, Gene expression, medicine, Animals, Humans, lamin, lcsh:QH573-671, Wnt Signaling Pathway, Actin, 030304 developmental biology, Cell Nucleus, 0303 health sciences, integumentary system, lcsh:Cytology, 030302 biochemistry & molecular biology, Wnt signaling pathway, Cell Biology, Lamin Type A, medicine.disease, Progerin, Actins, Chromatin, Cell biology, lcsh:Genetics, nuclear actin, progerin, NIH 3T3 Cells, gene expression, Lamin, Research Article, hutchinson-gilford progeria syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b80f90f21712ebd16646d8a4cc4220eTest

المؤلفون: Martin W. Hetzer, Ling Huang, Simone Bersini, Roberta Schulte, Hannah Tsai

المصدر: eLife, Vol 9 (2020)
eLife

مصطلحات موضوعية: 0301 basic medicine, Aging, Mouse, Vascular permeability, 030204 cardiovascular system & hematology, medicine.disease_cause, Mice, 0302 clinical medicine, Progeria, Phosphoprotein Phosphatases, Medicine, Biology (General), Glutathione Transferase, integumentary system, General Neuroscience, General Medicine, Cell biology, Tools and Resources, Endothelial stem cell, endothelial cell, medicine.symptom, Reprogramming, Human, hutchinson-gilford progeria syndrome, congenital, hereditary, and neonatal diseases and abnormalities, QH301-705.5, Science, Myocytes, Smooth Muscle, Inflammation, Bone morphogenetic protein, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Downregulation and upregulation, Animals, Humans, smooth muscle cell, General Immunology and Microbiology, business.industry, vascular barrier, nutritional and metabolic diseases, Endothelial Cells, medicine.disease, direct reprogramming, 030104 developmental biology, business, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3808a0e9cdb72e2f1c7214c0ade3a503Test
https://pubmed.ncbi.nlm.nih.gov/32896271Test