المؤلفون: Bakhoum, Samuel F, Ngo, Bryan, Laughney, Ashley M, Cavallo, Julie-Ann, Murphy, Charles J, Ly, Peter, Shah, Pragya, Sriram, Roshan K, Watkins, Thomas BK, Taunk, Neil K, Duran, Mercedes, Pauli, Chantal, Shaw, Christine, Chadalavada, Kalyani, Rajasekhar, Vinagolu K, Genovese, Giulio, Venkatesan, Subramanian, Birkbak, Nicolai J, McGranahan, Nicholas, Lundquist, Mark, LaPlant, Quincey, Healey, John H, Elemento, Olivier, Chung, Christine H, Lee, Nancy Y, Imielenski, Marcin, Nanjangud, Gouri, Pe’er, Dana, Cleveland, Don W, Powell, Simon N, Lammerding, Jan, Swanton, Charles, Cantley, Lewis C

المصدر: Nature. 553(7689)

مصطلحات موضوعية: Genetics, HIV/AIDS, Aetiology, 2.1 Biological and endogenous factors, Cancer, Animals, Brain Neoplasms, Breast Neoplasms, Carcinoma, Squamous Cell, Cell Line, Chromosomal Instability, Chromosome Segregation, Cytosol, DNA, Neoplasm, Female, Head and Neck Neoplasms, Humans, Inflammation, Membrane Proteins, Mesoderm, Mice, Micronuclei, Chromosome-Defective, NF-kappa B, Neoplasm Metastasis, Nucleotidyltransferases, Xenograft Model Antitumor Assays, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/27h418ppTest

المؤلفون: Lee, Gina, Zheng, Yuxiang, Cho, Sungyun, Jang, Cholsoon, England, Christina, Dempsey, Jamie M, Yu, Yonghao, Liu, Xiaolei, He, Long, Cavaliere, Paola M, Chavez, Andre, Zhang, Erik, Isik, Meltem, Couvillon, Anthony, Dephoure, Noah E, Blackwell, T Keith, Yu, Jane J, Rabinowitz, Joshua D, Cantley, Lewis C, Blenis, John

المصدر: Cell. 171(7)

مصطلحات موضوعية: Genetics, Aetiology, 1.1 Normal biological development and functioning, Underpinning research, 2.1 Biological and endogenous factors, Generic health relevance, Animals, Cell Nucleus, Cholesterol, Fatty Acids, Female, Gene Expression Regulation, Heterografts, Humans, Lipogenesis, Mechanistic Target of Rapamycin Complex 1, Mice, Mice, Nude, Neoplasm Transplantation, Protein Serine-Threonine Kinases, RNA Processing, Post-Transcriptional, Ribosomal Protein S6 Kinases, 70-kDa, Signal Transduction, CK1, RNA splicing, RNA stability, S6K1, SR proteins, SRPK2, cancer metabolism, de novo lipid synthesis, mTOR, nonsense-mediated decay, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2bt0k3czTest

المؤلفون: Hu, Hai, Juvekar, Ashish, Lyssiotis, Costas A, Lien, Evan C, Albeck, John G, Oh, Doogie, Varma, Gopal, Hung, Yin Pun, Ullas, Soumya, Lauring, Josh, Seth, Pankaj, Lundquist, Mark R, Tolan, Dean R, Grant, Aaron K, Needleman, Daniel J, Asara, John M, Cantley, Lewis C, Wulf, Gerburg M

المصدر: Cell. 164(3)

مصطلحات موضوعية: Underpinning research, 1.1 Normal biological development and functioning, Animals, Breast Neoplasms, Cell Line, Tumor, Cytoskeleton, Cytosol, Disease Models, Animal, Epithelial Cells, Fructose-Bisphosphate Aldolase, Glycolysis, Humans, Insulin, Mice, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Signal Transduction, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7hv4z168Test

المؤلفون: Bettaieb, Ahmed, Bakke, Jesse, Nagata, Naoto, Matsuo, Kosuke, Xi, Yannan, Liu, Siming, AbouBechara, Daniel, Melhem, Ramzi, Stanhope, Kimber, Cummings, Bethany, Graham, James, Bremer, Andrew, Zhang, Sheng, Lyssiotis, Costas A, Zhang, Zhong-Yin, Cantley, Lewis C, Havel, Peter J, Haj, Fawaz G

المصدر: Journal of Biological Chemistry. 288(24)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Diabetes, Obesity, Nutrition, Underpinning research, 1.1 Normal biological development and functioning, Metabolic and endocrine, 3T3-L1 Cells, Adipose Tissue, Brown, Adult, Aged, Amino Acid Substitution, Animals, Diet, High-Fat, Energy Metabolism, Gene Knockdown Techniques, Glucose Intolerance, Humans, Insulin Resistance, Macaca mulatta, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Middle Aged, Phosphorylation, Phosphotyrosine, Protein Interaction Domains and Motifs, Protein Interaction Mapping, Protein Processing, Post-Translational, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Pyruvate Kinase, Signal Transduction, Adipocyte, Metabolism, Tyrosine Protein Phosphatase, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9kk0r72cTest

المؤلفون: Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-Kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G

المصدر: Nature Chemical Biology. 8(10)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, Animals, Biopolymers, Blotting, Western, Cell Proliferation, Cell Transformation, Neoplastic, Enzyme Activators, Humans, Mice, Neoplasms, Pyruvate Kinase, Medicinal and Biomolecular Chemistry, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0s42k651Test

المؤلفون: Shaw, Reuben J., Lamia, Katja A., Vasquez, Debbie, Koo, Seung-Hoi, Bardeesy, Nabeel, DePinho, Ronald A., Montminy, Marc, Cantley, Lewis C.

المصدر: Science, 2005 Dec 01. 310(5754), 1642-1646.

الوصول الحر: https://www.jstor.org/stable/3842960Test

المؤلفون: Wang, Lei, Yang, Linda, Burns, Kevin, Kuan, Chia-Yi, Zheng, Yi, Cantley, Lewis C.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2005 Sep . 102(38), 13484-13489.

الوصول الحر: https://www.jstor.org/stable/3376659Test

المؤلفون: Luo, Ji, Sobkiw, Cassandra L., Logsdon, Nicole M., Watt, John M., Signoretti, Sabina, O'Connell, Fionnuala, Shin, Eyoung, Shim, Youngju, Pao, Lily, Neel, Benjamin G., DePinho, Ronald A., Loda, Massimo, Cantley, Lewis C.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2005 Jul . 102(29), 10238-10243.

الوصول الحر: https://www.jstor.org/stable/3375960Test

المؤلفون: Ueki, Kohjiro, Yballe, Claudine M., Brachmann, Saskia M., Vicent, David, Watt, John M., Kahn, C. Ronald, Cantley, Lewis C.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2002 Jan 01. 99(1), 419-424.

الوصول الحر: https://www.jstor.org/stable/3057552Test

المؤلفون: Satterthwaite, Anne B., Willis, Fiona, Kanchanastit, Prim, Fruman, David, Cantley, Lewis C., Helgason, Cheryl D., Humphries, R. Keith, Lowell, Clifford A., Simon, Melvin, Leitges, Michael, Tarakhovsky, Alexander, Tedder, Thomas F., Lesche, Ralf, Wu, Hong, Witte, Owen N.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2000 Jun 01. 97(12), 6687-6692.

الوصول الحر: https://www.jstor.org/stable/122698Test