المؤلفون: Tobias V Lanz, R Camille Brewer, Peggy P Ho, Kevin M Jude, Daniel Fernandez, Jae-Seung Moon, Ricardo A Fernandes, Alejandro M Gomez, Gabriel-Stefan Nadj, Christopher M Bartley, Ryan D Schubert, Isobel A Hawes, Sara E Vazquez, Manasi Iyer, J Bradley Zuchero, Bianca Teegen, Jeffrey E Dunn, Christopher B Lock, Lucas B Kipp, Victoria C Cotham, Beatrix M Ueberheide, Blake T Aftab, Mark S Anderson, Joseph L DeRisi, Michael R Wilson, Rachael JM Bashford-Rogers, Michael Platten, K Christopher Garcia, Lawrence Steinman, William H Robinson

المصدر: Nature
Nature, vol 603, iss 7900

مصطلحات موضوعية: Epstein-Barr Virus Infections, Herpesvirus 4, Human, Multiple Sclerosis, General Science & Technology, Nerve Tissue Proteins, Neurodegenerative, Autoimmune Disease, Article, Mice, Clinical Research, Genetics, 2.1 Biological and endogenous factors, Animals, Humans, Aetiology, Neuron-Glia, B-Lymphocytes, Multidisciplinary, Cell Adhesion Molecules, Neuron-Glia, Herpesvirus 4, Neurosciences, Brain Disorders, Infectious Diseases, Epstein-Barr Virus Nuclear Antigens, Neurological, Cell Adhesion Molecules, Human, Biotechnology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2318b2d41a42f0170e92995f810de60Test
https://doi.org/10.1038/s41586-022-04432-7Test

المؤلفون: Daniel W. Sherbenou, Thomas G. Martin, Olivia Perez De Acha, Byron Hann, Blake T. Aftab, Megan Murnane, Yang Su, Jeffery L. Wolf, Shelby C. Bearrows, Bin Liu, Christopher R. Behrens

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 26, iss 22
Clin Cancer Res

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Immunoconjugates, medicine.medical_treatment, Mice, 0302 clinical medicine, hemic and lymphatic diseases, Monoclonal, Multiple myeloma, Cancer, Tumor, Antibodies, Monoclonal, Hematology, Middle Aged, Intercellular Adhesion Molecule-1, Flow Cytometry, Antibodies, Anti-Idiotypic, Anti-Idiotypic, medicine.anatomical_structure, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Heterografts, Female, Development of treatments and therapeutic interventions, Multiple Myeloma, Biotechnology, Adult, Antibody-drug conjugate, medicine.drug_class, Oncology and Carcinogenesis, Monoclonal antibody, Article, Antibodies, Cell Line, 03 medical and health sciences, Rare Diseases, Clinical Research, In vivo, Cell Line, Tumor, medicine, Animals, Humans, Oncology & Carcinogenesis, Cell Proliferation, Aged, business.industry, Daratumumab, Immunotherapy, medicine.disease, ADP-ribosyl Cyclase 1, Orphan Drug, 030104 developmental biology, Cancer research, Bone marrow, business, Ex vivo

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c90915ca7c606383916fa2bf8e189cbTest
https://doi.org/10.1158/1078-0432.ccr-20-0400Test

المؤلفون: Amani Makkouk, Xue (Cher) Yang, Taylor Barca, Anthony Lucas, Mustafa Turkoz, Jonathan T S Wong, Kevin P Nishimoto, Mary M Brodey, Maryam Tabrizizad, Smitha R Y Gundurao, Lu Bai, Arun Bhat, Zili An, Stewart Abbot, Daulet Satpayev, Blake T Aftab, Marissa Herrman

المصدر: Journal for Immunotherapy of Cancer

مصطلحات موضوعية: Cancer Research, Carcinoma, Hepatocellular, T-Lymphocytes, Immunology, Apoptosis, Mice, SCID, cell engineering, adoptive, Immunotherapy, Adoptive, Mice, Glypicans, Mice, Inbred NOD, innate, Tumor Cells, Cultured, tumor microenvironment, Animals, Humans, Immunology and Allergy, Cell Proliferation, Interleukin-15, Pharmacology, Receptors, Chimeric Antigen, Immune Cell Therapies and Immune Cell Engineering, Liver Neoplasms, Receptors, Antigen, T-Cell, gamma-delta, immunity, Xenograft Model Antitumor Assays, Oncology, Leukocytes, Mononuclear, Molecular Medicine, Female, immunotherapy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e955ee28a80f5478bb3fb0c7d714e4Test
https://doi.org/10.1136/jitc-2021-003441Test

المؤلفون: Hui Liu, Yu Hsiu T. Lin, Megan Murnane, Geoffrey A. Smith, Christine Lam, Margarette C. Mariano, Arun P. Wiita, Jack Taunton, Sandy W. Wong, Jun O. Liu, Constantine S. Mitsiades, Blake T. Aftab, Ian Ferguson, Byron Hann

المصدر: Haematologica, vol 103, iss 7
Haematologica

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Ruxolitinib, Proteome, Cell Communication, Cardiorespiratory Medicine and Haematology, Plasma Cell Disorders, chemistry.chemical_compound, Mice, Piperidines, Bone Marrow, Tumor Microenvironment, 2.1 Biological and endogenous factors, Medicine, Aetiology, Cancer, Hematology, 3. Good health, STAT Transcription Factors, medicine.anatomical_structure, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Multiple Myeloma, medicine.drug, Signal Transduction, Stromal cell, Plasma Cells, Immunology, Article, 03 medical and health sciences, Rare Diseases, In vivo, Animals, Humans, Pyrroles, Protein Kinase Inhibitors, Janus Kinases, Tumor microenvironment, Tofacitinib, 5.2 Cellular and gene therapies, business.industry, Venetoclax, Animal, Mesenchymal stem cell, Drug Repositioning, Mesenchymal Stem Cells, Phosphoproteins, Xenograft Model Antitumor Assays, Disease Models, Animal, Orphan Drug, 030104 developmental biology, Pyrimidines, chemistry, Disease Models, Cancer research, Bone marrow, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3bb91b64a9c4e0fbaed43ab5969e84Test
https://escholarship.org/uc/item/99g7601fTest

المؤلفون: Jennifer N. Rauch, Bryan M. Dunyak, Byron Hann, Peter Walter, Martin Kampmann, Megan Murnane, Min Cho, Xiaokai Li, Teresa A. Colvin, Jason E. Gestwicki, Diego Acosta-Alvear, Blake T. Aftab, Jonathan S. Weissman, Michael Y. Sherman

المصدر: Molecular cancer therapeutics, vol 14, iss 3

مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Cancer Research, Oncology and Carcinogenesis, Allosteric regulation, Antineoplastic Agents, Pharmacology, BAG3, Article, Cell Line, Protein–protein interaction, Mice, Cell Line, Tumor, Proliferating Cell Nuclear Antigen, 2.1 Biological and endogenous factors, Animals, Humans, HSP70 Heat-Shock Proteins, Protein Interaction Domains and Motifs, Oncology & Carcinogenesis, Aetiology, Cancer, Adaptor Proteins, Signal Transducing, Cell Proliferation, Regulation of gene expression, Neoplastic, Tumor, biology, Effector, Forkhead Box Protein M1, Signal Transducing, Adaptor Proteins, Signal transducing adaptor protein, Forkhead Transcription Factors, Pharmacology and Pharmaceutical Sciences, Gene Expression Regulation, Neoplastic, Gene Expression Regulation, Oncology, Hela Cells, Chaperone (protein), MCF-7 Cells, Cancer research, biology.protein, FOXM1, Apoptosis Regulatory Proteins, HT29 Cells, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3b22505bee1d46a3729d48f13aa063Test
https://doi.org/10.1158/1535-7163.mct-14-0650Test

المؤلفون: P. Leif Bergsagel, Marta Chesi, Marianne Kraus, Christoph Driessen, Laura K. Shawver, Grace J. Lee, Blake T. Aftab, Szerenke Kiss von Soly, Mark Rolfe, Megan Murnane, Ronan Le Moigne, Jinhai Wang, Daniel Anderson, Jeffrey L. Wolf, Arun P. Wiita, Mary Kamala Menon, Emily M. King, Stevan Djakovic, David J. Wustrow, Ferdie Soriano, Constantine S. Mitsiades, Han Jie Zhou, Eduardo Valle, Stephen T. C. Wong, Thomas G. Martin, Zhi Yong Wu, Eugen Dhimolea, Christine Lam, F. Michael Yakes, Julie Rice, Bing Yao

المصدر: Molecular cancer therapeutics. 16(11)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Proteasome Endopeptidase Complex, Indoles, Apoptosis, Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Ubiquitin, P97 Inhibitor CB-5083, medicine, Animals, Humans, Nuclear protein, Multiple myeloma, Cell Proliferation, Adenosine Triphosphatases, Cell growth, Nuclear Respiratory Factor 1, Nuclear Proteins, medicine.disease, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Pyrimidines, Oncology, Proteasome, 030220 oncology & carcinogenesis, Unfolded protein response, Cancer research, biology.protein, Proteasome inhibitor, Unfolded Protein Response, Multiple Myeloma, Proteasome Inhibitors, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdabd665906a2c466a4f478c5ace23bbTest
https://pubmed.ncbi.nlm.nih.gov/28878026Test

المؤلفون: Peter Walter, Xiaobo Wu, Daniel W. Sherbenou, Bin Liu, Blake T. Aftab, Diego Acosta-Alvear, Thomas G. Martin, Aaron C Logan, Yang Su, Byron Hann, Marc A. Shuman, John P. Atkinson, Jeffrey L. Wolf, Arun P. Wiita, Christopher R. Behrens

المصدر: The Journal of clinical investigation, vol 126, iss 12

مصطلحات موضوعية: 0301 basic medicine, Immunoconjugates, Antibodies, Neoplasm, viruses, Cell, Gene Dosage, Medical and Health Sciences, Mice, Monoclonal, Multiple myeloma, Cancer, Tumor, biology, Antibodies, Monoclonal, General Medicine, Hematology, female genital diseases and pregnancy complications, 3. Good health, medicine.anatomical_structure, 5.1 Pharmaceuticals, Chromosomes, Human, Pair 1, Pair 1, Antibody, Development of treatments and therapeutic interventions, Multiple Myeloma, Human, Biotechnology, Research Article, Antibody-drug conjugate, medicine.drug_class, Immunology, Monoclonal antibody, Chromosomes, Antibodies, Cell Line, Membrane Cofactor Protein, 03 medical and health sciences, Rare Diseases, Clinical Research, Cell Line, Tumor, medicine, Genetics, Animals, Humans, Innate immune system, business.industry, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Cell culture, biology.protein, Cancer research, Neoplasm, Bone marrow, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4493ea8c812dbe33beb060ad3da7b1b3Test
https://europepmc.org/articles/PMC5127683Test/

المؤلفون: Philip A. Beachy, Alexandra Borodovsky, Daniel H. Kim, Baozhi Chen, Alexander Lee, Melika Rezaee, Ervin H. Epstein, James Kim, Jynho Kim, Gregory J. Riggins, Emily M. King, Charles M. Rudin, Blake T. Aftab, Jean Y. Tang

المصدر: Cancer Cell. 23(1):23-34

مصطلحات موضوعية: Cancer Research, Pyridines, Itraconazole, Antineoplastic Agents, Context (language use), Pharmacology, Biology, Arsenicals, Receptors, G-Protein-Coupled, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Arsenic Trioxide, GLI2, medicine, Animals, Anilides, Hedgehog Proteins, Arsenic trioxide, 030304 developmental biology, Medulloblastoma, 0303 health sciences, Oxides, Cell Biology, medicine.disease, Smoothened Receptor, Hedgehog signaling pathway, 3. Good health, chemistry, Oncology, Carcinoma, Basal Cell, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Smoothened, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e7ef15dfa1007e4c08e307d327c7a5Test

المؤلفون: Sanh Tan Lam, Edna F. Choo, Lillian Lee, Harvey Wong, Amy C. Peterson, Congfen Li, Yongchang Shi, Klaus P. Hoeflich, John Prescott, Geoffrey Del Rosario, Marcia Belvin, Jean-Francois Martini, Ron Aoyama, Peiwen Yu, Joeseph A Ware, Blake T. Aftab, Laurent Vernillet

المصدر: Clinical Cancer Research. 18:3090-3099

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Population, Mice, Nude, Antineoplastic Agents, Pharmacology, Models, Biological, Mice, Piperidines, Pharmacokinetics, In vivo, Cell Line, Tumor, Animals, Humans, Medicine, Potency, education, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase Kinases, education.field_of_study, business.industry, MEK inhibitor, Melanoma, medicine.disease, Xenograft Model Antitumor Assays, Oncology, Pharmacodynamics, Azetidines, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afddce05a73ecd664670ea98a745ceb1Test
https://doi.org/10.1158/1078-0432.ccr-12-0445Test

المؤلفون: Steve Wong, Jinhai Wang, Laura K. Shawver, Szerenke Kiss von Soly, Mark Rolfe, Julie Rice, Bing Yao, Brajesh Kumar, Martin Kampmann, Daniel Anderson, Eduardo Valle, Blake T. Aftab, Ronan Le Moigne, F. Michael Yakes, Zhi Yong Wu, Mary-Kamala Menon, Jonathan S. Weissman, Antonett Madriaga, Stevan Djakovic, Ferdie Soriano, Han-Jie Zhou, Yuwen Chen, David J. Wustrow

المصدر: Cancer cell, vol 28, iss 5

مصطلحات موضوعية: Cancer Research, Indoles, Nude, Apoptosis, Mice, SCID, Mice, 0302 clinical medicine, Neoplasms, Homeostasis, 2.1 Biological and endogenous factors, Molecular Targeted Therapy, Nuclear protein, Enzyme Inhibitors, Aetiology, Cancer, Regulation of gene expression, Adenosine Triphosphatases, 0303 health sciences, Tumor, Molecular Structure, Blotting, Reverse Transcriptase Polymerase Chain Reaction, Nuclear Proteins, Endoplasmic Reticulum-Associated Degradation, Ubiquitinated Proteins, AAA proteins, 3. Good health, Cell biology, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, RNA Interference, Western, Biotechnology, Blotting, Western, Oncology and Carcinogenesis, Mice, Nude, Biology, Endoplasmic-reticulum-associated protein degradation, SCID, Article, Cell Line, 03 medical and health sciences, Cell Line, Tumor, Genetics, ERAD pathway, Animals, Humans, Oncology & Carcinogenesis, 030304 developmental biology, Neoplastic, Endoplasmic reticulum, HEK 293 cells, Neurosciences, Cell Biology, HCT116 Cells, Xenograft Model Antitumor Assays, Pyrimidines, HEK293 Cells, Gene Expression Regulation, Unfolded protein response, CRISPR-Cas Systems, K562 Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c0010f90064594c471ccfefe9d9d4dTest
https://escholarship.org/uc/item/1mg4031wTest