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المؤلفون: Uwe Zangemeister-Wittke, Fabian Brandl, Andreas Plückthun, Martina Zimmermann, Martin Béhé, Hannes Merten
المصدر: Journal of Controlled Release. 307:379-392
مصطلحات موضوعية: Biodistribution, Recombinant Fusion Proteins, Pharmaceutical Science, 02 engineering and technology, DNA-binding protein, Mice, 03 medical and health sciences, chemistry.chemical_compound, Neoplasms, Animals, Distribution (pharmacology), Tissue Distribution, 030304 developmental biology, Tumor marker, 0303 health sciences, Chemistry, Epithelial cell adhesion molecule, Epithelial Cell Adhesion Molecule, 021001 nanoscience & nanotechnology, Fusion protein, Extravasation, Ankyrin Repeat, Cell biology, DARPin, Female, Peptides, 0210 nano-technology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2118c77f5bc0663751dc5d252d686eaTest
https://doi.org/10.1016/j.jconrel.2019.06.030Test -
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المؤلفون: Alexey A. Schulga, Daria Kiseleva, Sergey M. Deyev, Irina V. Balalaeva, E. A. Sokolova, O N Shilova
المصدر: International Journal of Molecular Sciences
Volume 20
Issue 10
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2399 (2019)مصطلحات موضوعية: 0301 basic medicine, Receptor, ErbB-2, medicine.medical_treatment, Muscle Proteins, immunogenicity, medicine.disease_cause, Targeted therapy, lcsh:Chemistry, Mice, 0302 clinical medicine, Ovarian carcinoma, Pseudomonas exotoxin, Molecular Targeted Therapy, lcsh:QH301-705.5, Spectroscopy, ADP Ribose Transferases, Ovarian Neoplasms, Mice, Inbred BALB C, far-red fluorescent protein, Pseudomonas exotoxin A, Immunogenicity, Immunotoxins, Nuclear Proteins, General Medicine, targeted therapy, Computer Science Applications, DARPin, Liver, 030220 oncology & carcinogenesis, Toxicity, Epitopes, B-Lymphocyte, Heterografts, Female, Cell Survival, Virulence Factors, Recombinant Fusion Proteins, Bacterial Toxins, Exotoxins, Mice, Nude, Antineoplastic Agents, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Inhibitory Concentration 50, Cell Line, Tumor, HER2, medicine, Biomarkers, Tumor, Animals, Humans, Amino Acid Sequence, Physical and Theoretical Chemistry, Molecular Biology, business.industry, Organic Chemistry, Carcinoma, medicine.disease, Xenograft Model Antitumor Assays, ovarian carcinoma, Disease Models, Animal, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Cancer research, Ovarian cancer, business, Exotoxin, Spleen
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5873f832e09f153de0037e4542245fTest
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المؤلفون: Fabian Zellweger, Monique Vogel, Alexander Eggel, Daniel Brigger, Pascal Gasser, Patrick Buschor
المصدر: Allergy. 72(8)
مصطلحات موضوعية: 0301 basic medicine, Allergy, Recombinant Fusion Proteins, Immunology, Mice, Transgenic, Cross Reactions, Immunoglobulin E, Cell Degranulation, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Hypersensitivity, Immunology and Allergy, Animals, Humans, Receptor, biology, Effector, Receptors, IgE, Binding protein, Receptors, IgG, Degranulation, medicine.disease, 3. Good health, Basophils, Disease Models, Animal, 030104 developmental biology, DARPin, Immunoglobulin G, Ribosome display, biology.protein, 030215 immunology, Protein Binding, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9828e285149bdc3bd73161a66b830edaTest
https://pubmed.ncbi.nlm.nih.gov/27997998Test -
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المؤلفون: Michael T. Stumpp, Ivo Sonderegger, H. Kaspar Binz, Douglas Phillips, Maya Gulotti-Georgieva, Patrik Forrer, Daniel Steiner, Denis Villemagne, Christof Zitt, Frieder W. Merz
المصدر: Protein engineering, designselection : PEDS. 30(9)
مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Recombinant Fusion Proteins, Genetic Vectors, Serum albumin, Gene Expression, Bioengineering, Monoclonal antibody, Biochemistry, 03 medical and health sciences, Mice, 0302 clinical medicine, Pharmacokinetics, In vivo, medicine, Escherichia coli, Animals, Humans, Cloning, Molecular, Molecular Biology, Serum Albumin, biology, Chemistry, Protein Stability, Hydrogen-Ion Concentration, Orders of magnitude (mass), Ankyrin Repeat, Macaca fascicularis, 030104 developmental biology, Drug development, DARPin, 030220 oncology & carcinogenesis, biology.protein, Ankyrin repeat, Biotechnology, Half-Life, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda304704d3ca688cb9dda6719e0dd75Test
https://pubmed.ncbi.nlm.nih.gov/29088432Test -
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المؤلفون: Gerard A. Rodrigues, Candice Hansen, Lisa M. Hernández, Keith A. Luhrs, Matthew Mason, James R. Burke, Thomas C. Hohman, Lori-Ann Christie
المصدر: Investigative Opthalmology & Visual Science. 59:5836
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, 0301 basic medicine, genetic structures, Angiogenesis, Recombinant Fusion Proteins, Angiogenesis Inhibitors, Vascular permeability, Retinal Neovascularization, Pharmacology, Capillary Permeability, Neovascularization, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Ranibizumab, Human Umbilical Vein Endothelial Cells, medicine, Animals, Humans, Corneal Neovascularization, Tube formation, Chemistry, Nuclear Proteins, General Medicine, medicine.disease, eye diseases, Bevacizumab, Disease Models, Animal, Vascular endothelial growth factor A, 030104 developmental biology, DARPin, Corneal neovascularization, 030221 ophthalmology & optometry, Blood Vessels, Calcium, Rabbits, medicine.symptom
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3ce73e8c1d47b7cf27d22af5e1befbTest
https://doi.org/10.1167/iovs.18-25307Test -
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المؤلفون: Goldstein, Robert, Sosabowski, Jane, Livanos, Maria, Leyton, Julius, Vigor, Kim, Bhavsar, Gaurav, Nagy-Davidescu, Gabriela, Rashid, Mohammed, Miranda, Enrique, Yeung, Jenny, Tolner, Berend, Plückthun, Andreas, Mather, Stephen, Meyer, Tim, Chester, Kerry
المساهمون: University of Zurich, Chester, Kerry
المصدر: European Journal of Nuclear Medicine and Molecular Imaging
مصطلحات موضوعية: Receptor, ErbB-2, Recombinant Fusion Proteins, Molecular imaging, 610 Medicine & health, Mice, Breast cancer, Coordination Complexes, HER2, Cell Line, Tumor, 10019 Department of Biochemistry, Animals, Humans, 2741 Radiology, Nuclear Medicine and Imaging, Tissue Distribution, skin and connective tissue diseases, neoplasms, Tomography, Emission-Computed, Single-Photon, Mice, Inbred BALB C, Indium Radioisotopes, Mammary Neoplasms, Experimental, General Medicine, Ankyrin Repeat, DARPin, Radiology Nuclear Medicine and imaging, SPECT, 570 Life sciences, biology, Original Article, Female, Radiopharmaceuticals, Protein Binding
وصف الملف: Goldstein et al. 2015.pdf - application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::09abcec372ac5df3fac9f32f4bf2ecffTest
https://doi.org/10.5167/uzh-113056Test -
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المؤلفون: Michael T. Stumpp, Julia Katharina Ahlskog, Christopher Seidel, Peter A. Campochiaro, Michael Baumann, Daniel Snell, Jikui Shen, Jing Tian, Aling Dong, Rebecca Stevens, Savira Ekawardhani, Takeshi Iwase, Sean F. Hackett
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Cancer Research, medicine.medical_specialty, Physiology, Angiogenesis, Recombinant Fusion Proteins, Clinical Biochemistry, Becaplermin, Mice, Transgenic, Pharmacology, Biology, Retinal Neovascularization, Article, chemistry.chemical_compound, Mice, Ischemia, medicine, Animals, Opsins, Retinal Detachment, Retinal, Exudative retinal detachment, Proto-Oncogene Proteins c-sis, Choroidal Neovascularization, Surgery, Rats, Vascular endothelial growth factor, Mice, Inbred C57BL, Vascular endothelial growth factor A, Choroidal neovascularization, DARPin, chemistry, Receptors, LDL, biology.protein, NIH 3T3 Cells, medicine.symptom, Injections, Intraocular, Platelet-derived growth factor receptor, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a294306d2f66d1050c4ff01101f3136fTest
https://europepmc.org/articles/PMC3999311Test/ -
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المؤلفون: Patricia, Martin-Killias, Martin-Killias, Patricia, Nikolas, Stefan, Sacha, Rothschild, Andreas, Plückthun, Uwe, Zangemeister-Wittke
المساهمون: University of Zurich, Plückthun, A
المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research
مصطلحات موضوعية: Cancer Research, Cell Survival, Virulence Factors, Recombinant Fusion Proteins, Bacterial Toxins, Exotoxins, Mice, Nude, Antineoplastic Agents, Biology, Protein Engineering, medicine.disease_cause, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Fusion Toxin, Cell Line, Tumor, medicine, 10019 Department of Biochemistry, Animals, Humans, 1306 Cancer Research, 030304 developmental biology, ADP Ribose Transferases, 0303 health sciences, Epithelial cell adhesion molecule, Neoplasms, Experimental, Protein engineering, Xenograft Model Antitumor Assays, Molecular biology, In vitro, Ankyrin Repeat, 3. Good health, Oncology, DARPin, Biochemistry, chemistry, Cell culture, 030220 oncology & carcinogenesis, Injections, Intravenous, Pseudomonas aeruginosa, 570 Life sciences, biology, Female, Ankyrin repeat, 2730 Oncology, Cell Adhesion Molecules, Exotoxin
وصف الملف: APpub0318_V.pdf - application/pdf; Clin_Cancer_Res-2010-Martin-Killias-1078-0432.CCR-10-1303.pdf - application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86840a7503fe783d9dd59f9ca21f8d9Test
https://doi.org/10.5167/uzh-43147Test -
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المؤلفون: Jeoung-Sook Shin, Beomkyu Kim, Gabriel Hobi, Beda M. Stadler, Theodore S. Jardetzky, Monique Vogel, Alexander Eggel, Günther Baravalle, Patrick Buschor, Patrik Forrer, Clemens A. Dahinden
المصدر: The Journal of allergy and clinical immunology
مصطلحات موضوعية: Models, Molecular, Allergy, Protein Conformation, Recombinant Fusion Proteins, Immunology, Mice, Transgenic, Omalizumab, Antibodies, Monoclonal, Humanized, medicine.disease_cause, Immunoglobulin E, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Immunology and Allergy, Mast Cells, Antigens, Anaphylaxis, 030304 developmental biology, 0303 health sciences, Dose-Response Relationship, Drug, biology, Receptors, IgE, Chemistry, Molecular Mimicry, medicine.disease, Ankyrin Repeat, Antibodies, Anti-Idiotypic, Basophils, 3. Good health, Molecular mimicry, 030228 respiratory system, DARPin, biology.protein, Antibody, Cell activation, Protein Binding, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b5d007f0043e77c6ee29f6b9812ec7Test
https://doi.org/10.1016/j.jaci.2014.02.005Test