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المؤلفون: Dinesh Rakheja, Sanchari Bhattacharyya, Masako Suzuki, Benjamin A. Gartrell, Xiaosheng Wu, Emily Ressigue, Bradley C. Leibovich, Alexander Tischer, John C. Cheville, Lou Ann Gross, John M. Greally, Yiyu Zou, Thomas E. Witzig, Tushar D. Bhagat, Venkata R. Machha, R. Houston Thompson, Amit Verma, Christine M. Lohse, Shanisha Gordon-Mitchell, Stephen A. Boorjian, Gaurav Choudhary, Lance C. Pagliaro, Kith Pradhan, Li Fan Wong, Ulrich Steidl, Niraj Shenoy, Katalin Susztak, Beamon Agarwal
المصدر: Journal of Clinical Investigation. 129:1612-1625
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Ascorbic Acid, Gene Expression Regulation, Enzymologic, Mice, 03 medical and health sciences, 0302 clinical medicine, Renal cell carcinoma, In vivo, Cell Line, Tumor, medicine, Animals, Humans, Epigenetics, Carcinoma, Renal Cell, Chemistry, Cancer, General Medicine, Methylation, medicine.disease, Ascorbic acid, Kidney Neoplasms, Gene Expression Regulation, Neoplastic, Alcohol Oxidoreductases, Editorial Commentary, Clear cell renal cell carcinoma, 030104 developmental biology, 030220 oncology & carcinogenesis, DNA methylation, 5-Methylcytosine, Cancer research, Female, Gene Deletion
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750099f155edb0673134c93f7a9f865eTest
https://doi.org/10.1172/jci98747Test -
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المؤلفون: Zi Yan, Rituparna Mukhopadhyay, Masako Suzuki, Boris Bartholdy, Eric E. Bouhassira, Shouping Zhang, John M. Greally, Julien Lajugie
المصدر: Blood Advances. 2:1833-1852
مصطلحات موضوعية: 0301 basic medicine, Erythroblasts, Biology, Response Elements, Cell Line, S Phase, 03 medical and health sciences, chemistry.chemical_compound, Red Cells, Iron, and Erythropoiesis, Humans, S phase, hemic and immune systems, Cell Differentiation, Promoter, Hematology, Methylation, DNA Methylation, Chromatin, Cell biology, DNA Demethylation, 030104 developmental biology, DNA demethylation, Differentially methylated regions, chemistry, DNA methylation, DNA
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24789d4253eb62453fb63436fd4bbe9fTest
https://doi.org/10.1182/bloodadvances.2018015651Test -
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المؤلفون: Orsolya Giricz, Deepak Nagrath, Yiyu Zou, Beamon Agarwal, John M. Greally, Matthias Bartenstein, Paola A. Guerrero, Srabani Sahu, Anirban Maitra, Srinivas Aluri, Changsoo Kwak, Tushar D. Bhagat, Shanisha Gordon-Mitchell, Brijesh Patel, Hongyun Zhao, Michael Goggins, Debabrata Banerjee, Davendra Sohal, Masako Suzuki, Lifeng Yang, Dagny Von Ahrens, Joelle Baddour, Sonal Gupta, Sanchari Bhattacharyya, Surinder K. Batra, Amit Verma, Gaurav Choudhary, Meelad M. Dawlaty, Ulrich Steidl, Prafulla Bhagat, Abhinav Achreja, Kith Pradhan, Yiting Yu
المصدر: eLife
eLife, Vol 8 (2019)مصطلحات موضوعية: 0301 basic medicine, Mouse, Epigenesis, Genetic, Mice, 0302 clinical medicine, Cancer-Associated Fibroblasts, pancreas, Biology (General), Epigenomics, Cancer Biology, biology, Chemistry, General Neuroscience, General Medicine, Cellular Reprogramming, Cell Transformation, Neoplastic, 030220 oncology & carcinogenesis, DNA methylation, 5-Methylcytosine, Medicine, Ketoglutaric Acids, Reprogramming, Carcinoma, Pancreatic Ductal, Research Article, Receptors, CXCR4, QH301-705.5, Science, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Pancreatic cancer, Cell Line, Tumor, medicine, stroma, Animals, Humans, Neoplasm Invasiveness, Epigenetics, Lactic Acid, Cell Proliferation, General Immunology and Microbiology, Mesenchymal stem cell, Mesenchymal Stem Cells, DNA Methylation, medicine.disease, Pancreatic Neoplasms, 030104 developmental biology, biology.protein, Cancer research, Demethylase, methylation, Stromal Cells, Transcriptome
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7428ffb16c7e0c51d33447be0990ccc8Test
https://pubmed.ncbi.nlm.nih.gov/31663852Test -
4Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts
المؤلفون: Yidong Wang, Bingruo Wu, Donghong Zhang, John M. Greally, Deyou Zheng, Ping Wang, Bin Zhou, Tamilla Nechiporuk, Pengfei Lu, Thomas Floss
المصدر: Nucleic Acids Research
Nucleic Acids Res. 45, 3102-3115 (2017)مصطلحات موضوعية: 0301 basic medicine, Potassium Channels, Biology, 03 medical and health sciences, Mice, Transcription (biology), Gene expression, Genetics, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Gene silencing, Animals, Epigenetics, DNA (Cytosine-5-)-Methyltransferases, Gene Silencing, Transcription factor, Cells, Cultured, Regulation of gene expression, Binding Sites, Myocardium, Gene regulation, Chromatin and Epigenetics, Gene Expression Regulation, Developmental, Heart, Methylation, DNA Methylation, Molecular biology, Mice, Inbred C57BL, Repressor Proteins, 030104 developmental biology, DNA methylation, CpG Islands, Protein Binding
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a62a964209e8c4ca2d708095332f51Test
http://europepmc.org/articles/PMC5389556Test -
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المؤلفون: Emily Bernstein, Hoa Nguyen, Gaston Habets, Gregg B. Fields, Chao Zhang, Tushar D. Bhagat, Elizabeth A. Burton, Yiting Yu, Evripidis Gavathiotis, Amit Verma, Veronika Polishchuk, Chiara Vardabasso, John M. Greally, Kith Pradhan, Paraic A. Kenny, Douglas B. Johnson, Matthias Bartenstein, E. Richard Stanley, Gideon Bollag, Yongkai Mo, Brian L. West, Kimberly B. Dahlman, Bernice Matusow, James Tsai, Rafe Shellooe, Orsolya Giricz, Xiomaris M. Cotto-Rios, Jeffrey A. Sosman
مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Proto-Oncogene Proteins B-raf, MAP Kinase Signaling System, THP-1 Cells, Transplantation, Heterologous, Antineoplastic Agents, Biology, 03 medical and health sciences, Mice, Downregulation and upregulation, RNA interference, Cell Line, Tumor, medicine, Animals, Humans, Epigenetics, neoplasms, Melanoma, Mitogen-Activated Protein Kinase Kinases, Mice, Inbred BALB C, Kinase, Interleukins, Drug Synergism, General Medicine, Methylation, U937 Cells, DNA Methylation, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Drug Resistance, Neoplasm, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, DNA methylation, Core Binding Factor Alpha 2 Subunit, Mutation, Cancer research, Female, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d6c5e0043ccf47a9e44247d6ebb7d7Test
https://europepmc.org/articles/PMC6124424Test/ -
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المصدر: Methods in Molecular Biology ISBN: 9781493978649
مصطلحات موضوعية: 0301 basic medicine, Differential display, Massive parallel sequencing, HpaII, Methylation, Genome, Molecular biology, 03 medical and health sciences, 5-Methylcytosine, chemistry.chemical_compound, 030104 developmental biology, Adapter (genetics), chemistry, DNA methylation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7cca66601fe63aecef12a1be23e2dd28Test
https://doi.org/10.1007/978-1-4939-7865-6_12Test -
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المؤلفون: Yi-An Ko, Kristin Ware, X. Shirley Liu, Orsolya Giricz, Sanchari Bhattacharya, Yiting Yu, Caroline Hu, Krishna Gundabolu, Ae Seo Deok Park, John M. Greally, Nishanth Vallumsetla, Katalin Susztak, James Pullman, Amit Verma, María Concepción Izquierdo, Masako Suzuki, Davoud Mohtat, Niraj Shenoy, Tushar D. Bhagat
المصدر: Clinical Cancer Research. 20:4349-4360
مصطلحات موضوعية: Cancer Research, Biology, Real-Time Polymerase Chain Reaction, Bioinformatics, medicine.disease_cause, Article, Epigenesis, Genetic, Cohort Studies, Biomarkers, Tumor, medicine, Humans, RNA, Messenger, Epigenetics, Promoter Regions, Genetic, Enhancer, Carcinoma, Renal Cell, Cells, Cultured, Regulation of gene expression, Reverse Transcriptase Polymerase Chain Reaction, Promoter, Methylation, DNA Methylation, Prognosis, Kidney Neoplasms, Gene Expression Regulation, Neoplastic, Survival Rate, Enhancer Elements, Genetic, HELP assay, Oncology, Organ Specificity, Case-Control Studies, DNA methylation, Cancer research, Carcinogenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe27a0121ef1a20b5100e3081ad2359fTest
https://doi.org/10.1158/1078-0432.ccr-14-0494Test -
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المؤلفون: Aaron Golden, Cathal Seoighe, Laurence J. Egan, John M. Greally, Alan Barnicle
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Receptors, Retinoic Acid, Inflammation, Biology, Receptor Tyrosine Kinase-like Orphan Receptors, Inflammatory bowel disease, in-vivo, Transcriptome, 03 medical and health sciences, inflammatory bowel disease, Gene expression, medicine, Humans, intestinal epithelium, Intestinal Mucosa, Molecular Biology, Gene, ulcerative colitis, DNA methylation, Brief Report, crohns-disease, colorectal-cancer, Nuclear Proteins, intestinal epithelial cell, chromatin-state, Methylation, Middle Aged, medicine.disease, Ulcerative colitis, gene-expression, 030104 developmental biology, crypt-villus axis, Cancer research, Hepatocyte Nuclear Factor 3-beta, human epigenomes, Colitis, Ulcerative, Female, medicine.symptom, transcriptome, bowel-disease, colon-cancer
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68cd28ec9ac58d060defff0ee9a0a2eTest
http://hdl.handle.net/10379/10357Test -
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المؤلفون: N. Ari Wijetunga, Maria Abadi, John M. Greally, Nicolas F. Schlecht, Kathleen Whitney, Thomas J. Belbin, Mark H. Einstein, Robert D. Burk
المصدر: Gynecologic oncology. 142(3)
مصطلحات موضوعية: 0301 basic medicine, Adult, Uterine Cervical Neoplasms, Cervical intraepithelial neoplasia, Article, Epigenesis, Genetic, 03 medical and health sciences, Young Adult, 0302 clinical medicine, CDKN2A, medicine, Cyclin-Dependent Kinase Inhibitor p18, Humans, Genes, Tumor Suppressor, Cancer epigenetics, Epigenetics, neoplasms, Cyclin-Dependent Kinase Inhibitor p16, Aged, Cervical cancer, Oncogene Proteins, business.industry, Genes, p16, Obstetrics and Gynecology, Methylation, DNA Methylation, Middle Aged, medicine.disease, Uterine Cervical Dysplasia, Biomarker (cell), 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, Disease Progression, Female, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60234fde7079a2a5c26e7f8d4ebc885bTest
https://pubmed.ncbi.nlm.nih.gov/27401842Test -
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المؤلفون: Nir Barzilai, Ciprian P. Gheorghe, Hong Qian Liang, Gil Atzmon, Reid F. Thompson, John M. Greally, Christina Lowes
المصدر: Aging Cell. 9:506-518
مصطلحات موضوعية: Genetics, Gene expression profiling, Aging, Epigenetics of physical exercise, DNA methylation, Promoter, Cell Biology, Methylation, Epigenetics, Biology, Gene, Epigenomics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::29f88b668bdc467a3d6bba2485681467Test
https://doi.org/10.1111/j.1474-9726.2010.00577.xTest