Attention-deficit/hyperactivity disorder drugs and growth: an Italian prospective observational study
| العنوان: | Attention-deficit/hyperactivity disorder drugs and growth: an Italian prospective observational study |
|---|---|
| المؤلفون: | Germinario, Ea, Arcieri, R, Bonati, M, Zuddas, A, Masi, G, Vella, S, Chiarotti, F, Panei, P, Italian ADHD Regional Reference Centers, Bobba, B, Veneselli, EDVIGE MARIA, Baldizzone, Mj, De Nobili, G, Marcelli, M, Torrioli, Mg, Vicari, S, Bartolomeo, S, Curatolo, P, Fabrizi, A, Donfrancesco, R, Parisi, R, Suglia, D, Nicoletta, M, Stagi, P, Murru, F, Tullini, A, Chiodo, S, Pirisi, A, Morbin, E, Milantoni, L, Bernardina, Bd, Maschietto, D, Mambelli, C, Condini, A, Brighenti, M, Miottello, P, Tombolato, R, Rizzo, L, Gemma, A, Musumeci, S, Vanadia, F, Costanza, G, Ragusa, D, Calamoneri, F, Mazzone, D, Giaccherini, F, Carrozzi, M, Cremaschi, S, Ottolini, A, Arisi, D, Tiberti, A, Terragni, Ml, Morosini, P, Meraviglia, C, Lenti, C, Pezzani, M, Balottin, U, Piccinelli, P, Chiarenza, G, Brunati, E, Montrasio, V, Molteni, M, Rinaldi, F, Rossi, G, Segala, R, Guccione, F, Bailo, P, Besana, D, Bassi, B, Rolando, M, Jarre, L, Ragazzo, F, Tondi, M, Casara, G, Arcangeli, D, Stermann, I, Giannelli, C, Voltolin, G, Legge, Mp, Sechi, E, Gennaro, E, Campolo, G, La Vitola, A, Mingolla, A, Spina, A, Margari, L, Massagli, A, Bravaccio, C, Granato, R, Grimaldi, G, Mazzotta, G, Cioni, G, Pincherle, M, Cesare, C, Stoppioni, V, Rosolino, T. |
| المساهمون: | Bobba, B, Veneselli, E, Baldizzone, Mj, De Nobili, G, Marcelli, M, Torrioli, Mg, Vicari, S, Bartolomeo, S, Curatolo, P, Fabrizi, A, Donfrancesco, R, Parisi, R, Suglia, D, Nicoletta, M, Stagi, P, Murru, F, Tullini, A, Chiodo, S, Pirisi, A, Morbin, E, Milantoni, L, Bernardina, Bd, Maschietto, D, Mambelli, C, Condini, A, Brighenti, M, Miottello, P, Tombolato, R, Rizzo, L, Gemma, A, Musumeci, S, Vanadia, F, Costanza, G, Ragusa, D, Calamoneri, F, Mazzone, D, Giaccherini, F, Carrozzi, M, Cremaschi, S, Ottolini, A, Arisi, D, Tiberti, A, Terragni, Ml, Morosini, P, Meraviglia, C, Lenti, C, Pezzani, M, Balottin, U, Piccinelli, P, Chiarenza, G, Brunati, E, Montrasio, V, Molteni, M, Rinaldi, F, Rossi, G, Segala, R, Guccione, F, Bailo, P, Besana, D, Bassi, B, Rolando, M, Jarre, L, Ragazzo, F, Zuddas, A, Tondi, M, Casara, G, Arcangeli, D, Stermann, I, Giannelli, C, Voltolin, G, Legge, Mp, Sechi, E, Gennaro, E, Campolo, G, La Vitola, A, Mingolla, A, Spina, A, Margari, L, Massagli, A, Bravaccio, C, Granato, R, Grimaldi, G, Mazzotta, G, Masi, G, Cioni, G, Pincherle, M, Cesare, C, Stoppioni, V, Rosolino, T. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Male, Pediatrics, medicine.medical_specialty, Percentile, Adolescent, Body weight, Atomoxetine Hydrochloride, Child Development, mental disorders, medicine, Attention deficit hyperactivity disorder, Humans, Pharmacology (medical), Prospective Studies, Registries, Prospective cohort study, Child, Adrenergic Uptake Inhibitors, Propylamines, Methylphenidate, Atomoxetine, Body Weight, Original Articles, Adolescent Development, medicine.disease, Body Height, Surgery, Psychiatry and Mental health, Italy, Attention Deficit Disorder with Hyperactivity, Pediatrics, Perinatology and Child Health, Observational study, Central Nervous System Stimulants, Female, Psychology, human activities, medicine.drug, Atomoxetine hydrochloride |
| الوصف: | This study was conducted to assess the long-term effect of methylphenidate (MPH) or atomoxetine (ATX) on growth in attention-deficit/hyperactivity disorder (ADHD) drug-naïve children.The study was an observational, post-marketing, fourth phase study.Data on height and weight were collected at baseline and every 6 months up to 24 months.Both ATX and MPH lead to decreased height gain (assessed by means of z-scores); the effect was significantly higher for ATX than for MPH. At any time, height z-score decrease in the ATX group was higher than the corresponding decrease observed in the MPH group, but the difference was significantly relevant only during the first year of treatment. An increment of average weight was observed both in patients treated with MPH and in those treated with ATX. However, using Tanner's percentile, a subset of patients showed a degree of growth lower than expected. This negative effect was significantly higher for ATX than for MPH.We conclude that ADHD drugs show a negative effect on linear growth in children in middle term. Such effect appears more evident for ATX than for MPH. |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae7ac7f6e78e522719f9b26a726c058Test http://hdl.handle.net/2318/146096Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bae7ac7f6e78e522719f9b26a726c058 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |