المؤلفون: Jessie D. Trujillo, Emily R. Miraldi, Jan Bakker, Benjamin R. tenOever, Andre L. Moreira, Helen Ray-Jones, Ivan Marazzi, Simin Zheng, Nan Zhao, Laura Campisi, Michael Schotsaert, Zeyu Zhu, Sven Heinz, Elaine Shum, Christopher Benner, Jessica Sook Yuin Ho, Anna Junxia Zhang, Adolfo García-Sastre, Sreeja Parameswaran, Joseph A. Wayman, Matthew T. Weirauch, Anand D. Jeyasekharan, Yesai Fstkchyan, Igor Morozov, Wen-Chun Liu, Minji Byun, Sumit K. Chanda, Sabarish V. Indran, Natasha N. Gaudreault, Mikhail Spivakov, Honglin Chen, Alba Escalera, Bobo Wing-Yee Mok, Kris M. White, Juergen A. Richt, Mariano Carossino, Valeriya Malysheva, Randy A. Albrecht, Tristan X. Jordan, Teresa Aydillo, Robert Sebra, Betsaida Salom Melo, Andrew Chak-Yiu Lee, Sonia Jangra, Udeni B. R. Balasuriya, David A. Meekins, Ernesto Guccione, Siu Ying Lau, Soner Yildiz, Michiel J. Thiecke, David A. Kaufman, Raveen Rathnasinghe, Honglian Liu

المساهمون: Intensive Care

المصدر: Cell, 184(10), 2618-2632.e17. Cell Press
Cell, vol 184, iss 10
Cell

مصطلحات موضوعية: THP-1 Cells, Type I, Pharmacology, Medical and Health Sciences, Transgenic, Mice, 0302 clinical medicine, inducible genes, Chlorocebus aethiops, Lung, topoisomerase, 0303 health sciences, Biological Sciences, Infectious Diseases, 5.1 Pharmaceuticals, cytokine storm, Pneumonia & Influenza, Development of treatments and therapeutic interventions, medicine.symptom, transcription, medicine.drug, Genetically modified mouse, Inflammation, Biology, Topoisomerase-I Inhibitor, Article, General Biochemistry, Genetics and Molecular Biology, Proinflammatory cytokine, Vaccine Related, 03 medical and health sciences, Pharmacotherapy, topotecan, Biodefense, medicine, Animals, Humans, Vero Cells, 030304 developmental biology, Mesocricetus, epigenetics, SARS-CoV-2, Prevention, Inflammatory and immune system, Topoisomerase, COVID-19, Pneumonia, medicine.disease, COVID-19 Drug Treatment, Emerging Infectious Diseases, Good Health and Well Being, inflammation, biology.protein, chromatin, Topotecan, Topoisomerase I Inhibitors, Cytokine storm, 030217 neurology & neurosurgery, DNA Topoisomerases, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d169781a64bf58af62230f5b19d8e6adTest
https://pure.eur.nl/en/publications/c6a3d84a-3a2d-4ff6-9904-1d7f6b018446Test

المؤلفون: Jessica Sook Yuin Ho, Bobo Wing-Yee Mok, Laura Campisi, Tristan Jordan, Soner Yildiz, Sreeja Parameswaran, Joseph A Wayman, Natasha N Gaudreault, David A Meekins, Sabarish V. Indran, Igor Morozov, Jessie D Trujillo, Yesai S Fstkchyan, Raveen Rathnasinghe, Zeyu Zhu, Simin Zheng, Nan Zhao, Kris White, Helen Ray-Jones, Valeriya Malysheva, Michiel J Thiecke, Siu-Ying Lau, Honglian Liu, Anna Junxia Zhang, Andrew Chak-Yiu Lee, Wen-Chun Liu, Teresa Aydillo, Betsaida Salom Melo, Ernesto Guccione, Robert Sebra, Elaine Shum, Jan Bakker, David A. Kaufman, Andre L. Moreira, Mariano Carossino, Udeni B R Balasuriya, Minji Byun, Emily R Miraldi, Randy A Albrecht, Michael Schotsaert, Adolfo Garcia-Sastre, Sumit K Chanda, Anand D Jeyasekharan, Benjamin R TenOever, Mikhail Spivakov, Matthew T Weirauch, Sven Heinz, Honglin Chen, Christopher Benner, Juergen A Richt, Ivan Marazzi

المصدر: bioRxiv

مصطلحات موضوعية: Genetically modified mouse, THP-1 Cells, Inflammation, Mice, Transgenic, Pharmacology, Article, Proinflammatory cytokine, Mice, In vivo, Chlorocebus aethiops, medicine, Animals, Humans, Epigenetics, Vero Cells, biology, Mesocricetus, business.industry, SARS-CoV-2, Topoisomerase, COVID-19, In vitro, COVID-19 Drug Treatment, DNA Topoisomerases, Type I, biology.protein, Topotecan, medicine.symptom, Topoisomerase I Inhibitors, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0569b26060aba6559d1d01d0d172051Test
https://pubmed.ncbi.nlm.nih.gov/33836156Test

المؤلفون: Siwen Liu, Pin Chen, Bobo Mok, Siu-Ying Lau, Honglin Chen, Kenneth Siu Sing Leung, Honglian Liu, Andrew Chak-Yiu Lee, Jasper Fuk-Woo Chan, Shaofeng Deng, Kwok-Yung Yuen, Eddie Lam-Kwong Lee, Jinxia Zhang, Hiu-Yin Lao, Conor J. Cremin, Gilman Kit Hang Siu, Kwok-Hung Chan, Kelvin K. W. To, Pui Wang, Timothy Ting-Leung Ng

مصطلحات موضوعية: Titer, Respiratory distress, Transmission (medicine), Mutant, medicine, Hamster, Disease, Biology, medicine.symptom, Virology, Asymptomatic, Virus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a1155ef4a00acd5519b1d41b13343aTest
https://doi.org/10.21203/rs.3.rs-81279/v1Test

المؤلفون: Xing Yao, Lanjuan Li, Hainv Gao, Shichang Xia, Shigui Yang, Jifang Sheng, Yanjun Zhang, Dawei Cui, Jade Lee-Lee Teng, Yu Chen, Yun-Tao Zhang, Qiang Fang, Nanping Wu, Haibo Wu, Jasper Fuk-Woo Chan, Hongyan Diao, Honglin Chen, Pui Wang, Kwok-Hung Chan, Hangping Yao, Min Zheng, Kwok-Yung Yuen, Yongcheng Li, Shufa Zheng, Wenjun Song, Kelvin K. W. To, Weifeng Liang, Siu-Ying Lau, Jianer Wo, Hoi-Wah Tsoi

المصدر: Lancet (London, England)

مصطلحات موضوعية: Male, China, medicine.drug_class, viruses, Antibiotics, Genome, Viral, Biology, medicine.disease_cause, Communicable Diseases, Emerging, Poultry, Article, Virus, Zoonoses, Influenza, Human, medicine, Animals, Humans, Transmission (medicine), General Medicine, Middle Aged, medicine.disease, Virology, Influenza A virus subtype H5N1, Influenza A virus, Influenza in Birds, Viral evolution, Sputum, Female, Human Virus, medicine.symptom, Tomography, X-Ray Computed, Pneumonia (non-human)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee40bd87f8ba5998cb44644994a4fc7Test
https://doi.org/10.1016/s0140-6736Test(13)60903-4

المؤلفون: Jian Zheng, Wenwei Tu, Zheng Xiang, Yinping Liu, Wai-Lan Wu, Siu-Ying Lau, Ming Liu, Kwok-Yung Yuen, Kwok-Hung Chan, Yu-Lung Lau, Jasper Fuk-Woo Chan, Honglin Chen, Lanjuan Li, Kelvin K. W. To, Kwok-Tai Lam

المصدر: PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0135999 (2015)

مصطلحات موضوعية: Oseltamivir, Blotting, Western, lcsh:Medicine, Pamidronate, Inflammation, Apoptosis, medicine.disease_cause, Influenza A Virus, H7N9 Subtype, Real-Time Polymerase Chain Reaction, Virus Replication, Virus, Immunoenzyme Techniques, chemistry.chemical_compound, Mice, Orthomyxoviridae Infections, T-Lymphocyte Subsets, Influenza, Human, medicine, Influenza A virus, Animals, Humans, RNA, Messenger, lcsh:Science, Lung, Cells, Cultured, Mice, Knockout, Multidisciplinary, biology, Bone Density Conservation Agents, Diphosphonates, Reverse Transcriptase Polymerase Chain Reaction, lcsh:R, DNA-Binding Proteins, Viral replication, chemistry, Granzyme, Perforin, Immunology, biology.protein, lcsh:Q, medicine.symptom, Viral load, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc405af8e04ecafa11ed92592a00499Test
http://europepmc.org/articles/PMC4540487Test

المؤلفون: Qiaoyun Zhu, Shigui Yang, Shufa Zheng, Siu-Ying Lau, Li Tian, David Cui, Jianzhou Lou, Xichao Guo, Jian Fan, Xianzhi Yang, Guoliang Xie, Yu Chen, Yuejiao Dong, Xuefen Li, Fei Yu, Zhaoxia Huo, Xiaofeng Huang

المصدر: BMC Infectious Diseases

مصطلحات موضوعية: Male, China, Avian influenza, Biology, Influenza A Virus, H7N9 Subtype, Real-Time Polymerase Chain Reaction, Rnase P, medicine.disease_cause, H5N1 genetic structure, Virus, Madin Darby Canine Kidney Cells, H7N9, Dogs, Limit of Detection, Influenza, Human, Multiplex polymerase chain reaction, Influenza A virus, medicine, Animals, Humans, Multiplex, Reverse Transcriptase Polymerase Chain Reaction, Virology, Influenza A virus subtype H5N1, Detection, Infectious Diseases, Molecular Diagnostic Techniques, Multiplex real-time RT-PCR, biology.protein, Sputum, Female, medicine.symptom, Multiplex Polymerase Chain Reaction, Neuraminidase, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ecb5549fe5f9ced03c39d5ba7ef467Test