نتائج البحث - "Lipoxygenase"

1

Natural Inhibitors against Potential Targets of Cyclooxygenase, Lipoxygenase and Leukotrienes

المؤلفون: Sisir Nandi, Sudatta Dey, Rishita Dey, Asmita Samadder, Anil Saxena

المصدر: Combinatorial Chemistry & High Throughput Screening. 25:2341-2357

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fbd5d995ba1b23b58e403774b6fef7Test
https://doi.org/10.2174/1386207325666210917111847Test

2

Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition

المؤلفون: Mosaad S. Mohamed, Shahenda Mahgoub, Hend Medhat El-Shanbaky, Rania H. Abd El-Hameed, Sahar A. Ali

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 977-986 (2021)

مصطلحات موضوعية: Chemokine, medicine.drug_class, Inflammation, RM1-950, 01 natural sciences, Anti-inflammatory, Lipoxygenase, Structure-Activity Relationship, 4-Butyrolactone, Heterocyclic Compounds, Drug Discovery, medicine, Humans, 15-LOX inhibitors, Lipoxygenase Inhibitors, Pyridazinone, anti-inflammatory, Pharmacology, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, biology, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Tumor Necrosis Factor-alpha, TNF-α inhibitor, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Biochemistry, Cyclooxygenase 2, biology.protein, Tumor necrosis factor alpha, selective COX-2 inhibitor, Cyclooxygenase, Therapeutics. Pharmacology, medicine.symptom, Research Article, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19667daf6d13bb3c9f348e6d97dfab69Test
http://europepmc.org/articles/PMC8118430Test

3

From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution

المؤلفون: Antonietta Rossi, Tran Hung, Oliver Werz, Christina Weinigel, Rossella Bilancia, Birgit Waltenberger, Zhigang Rao, Veronika Temml, Hermann Stuppner, Christian Kretzer, Carsten Giesel, Andreas Koeberle, Stefan Schwaiger, Silke Rummler, Alilou Mostafa, Tran Thi Van Anh, Paul M. Jordan, Simona Pace

المساهمون: Van Anh, T. T., Mostafa, A., Rao, Z., Pace, S., Schwaiger, S., Kretzer, C., Temml, V., Giesel, C., Jordan, P. M., Bilancia, R., Weinigel, C., Rummler, S., Waltenberger, B., Hung, T., Rossi, A., Stuppner, H., Werz, O., Koeberle, A.

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1629-1647 (2021)

مصطلحات موضوعية: 12-HHT, 12(S)-hydroxy-5-cis-8,10-trans-heptadecatrienoic acid, Lipoxygenase, UPLC‒MS/MS, ultra-performance liquid chromatography–tandem mass spectrometry, chemistry.chemical_compound, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, 0302 clinical medicine, RP, reversed phase, mPGES-1, microsomal prostaglandin E2 synthase 1, General Pharmacology, Toxicology and Pharmaceutics, Prostaglandin E2, LOX, lipoxygenase, chemistry.chemical_classification, DPPH, 2,2-diphenyl-1-picrylhydrazyl, 0303 health sciences, biology, ESI, electrospray ionization, Rv, resolvin, Biflavonoid, SPM, specialized pro-resolving mediators, PMNL, polymorphonuclear neutrophils, Cell biology, MaR, maresin, PBMC, peripheral blood mononuclear cells, SPE, solid phase extraction, Lipid mediator, HPLC, high performance liquid chromatography, PD, protectin, 030220 oncology & carcinogenesis, Original Article, medicine.symptom, medicine.drug, DAD, diode array detector, Leukotriene Production, Allosteric regulation, LT, leukotriene, Inflammation, RM1-950, Natural product, 03 medical and health sciences, Biosynthesis, ECD, electronic circular dichroism, LTC4S, leukotriene C4 synthase, medicine, IFN, interferon, PG, prostaglandin, 030304 developmental biology, Lipidomic, TX, thromboxane, 5-H(p)ETE, 5-hydro(pero)xy-eicosatetraenoic acid, Lipid signaling, HR, high resolution, sEH, soluble epoxide hydrolase, IL, interleukin, COX, cyclooxygenase, chemistry, Lipidomics, biology.protein, Therapeutics. Pharmacology, FCS, fetal calf serum, Resolution