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المؤلفون: Rachael A Lawson, Seyed Ehsan Saffari, David J. Brooks, Zheyu Xu, Kirstie N. Anderson, Nicola Pavese, K. Ray Chaudhuri
المصدر: Xu, Z, Anderson, K N, Saffari, S E, Lawson, R A, Chaudhuri, K R, Brooks, D & Pavese, N 2021, ' Progression of sleep disturbances in Parkinson's disease : a 5-year longitudinal study ', Journal of Neurology, vol. 268, no. 1, pp. 312-320 . https://doi.org/10.1007/s00415-020-10140-xTest
Journal of Neurologyمصطلحات موضوعية: Sleep Wake Disorders, Pediatrics, medicine.medical_specialty, Insomnia, Neurology, Parkinson's disease, Excessive daytime sleepiness, REM Sleep Behavior Disorder, REM sleep behavior disorder, RBD, EDS, 03 medical and health sciences, PPMI, 0302 clinical medicine, DISORDER SCREENING QUESTIONNAIRE, QUALITY-OF-LIFE, Humans, BEHAVIOR DISORDER, Medicine, Longitudinal Studies, 030212 general & internal medicine, Sleep disorder, Original Communication, business.industry, Epworth Sleepiness Scale, Parkinson Disease, medicine.disease, Sleep in non-human animals, DYSFUNCTION, EVOLUTION, PREVALENCE, EXCESSIVE DAYTIME SLEEPINESS, Parkinson’s disease, EARLY-STAGE, Neurology (clinical), medicine.symptom, Sleep, NONMOTOR SYMPTOMS, business, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34b78919ca0a5379e48b273c65b102aTest
https://doi.org/10.1007/s00415-020-10140-xTest -
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المصدر: Pasquini, J, Ceravolo, R, Brooks, D J, Bonuccelli, U & Pavese, N 2020, ' Progressive loss of raphe nuclei serotonin transporter in early Parkinson's disease : A longitudinal 123 I-FP-CIT SPECT study ', Parkinsonism & Related Disorders, vol. 77, pp. 170-175 . https://doi.org/10.1016Test/j.parkreldis.2019.03.025
مصطلحات موضوعية: 0301 basic medicine, Serotonin, Parkinson's disease, Population, Excessive daytime sleepiness, Physiology, Non-motor symptoms, Serotonergic, 03 medical and health sciences, 0302 clinical medicine, medicine, education, Serotonin transporter, education.field_of_study, Progression, Raphe, biology, business.industry, medicine.disease, Raphe nuclei, 030104 developmental biology, Neurology, biology.protein, Neurology (clinical), Geriatrics and Gerontology, medicine.symptom, business, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81e4ce802d76873a301037f59aa9f86Test
https://doi.org/10.1016Test/j .parkreldis.2019.03.025 -
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المؤلفون: David J. Brooks, Anne M. Landau, Majken B. Thomsen, Anna C. Schacht, Thea P. Lillethorup, Jan Jacobsen, Mette Kildevæld Simonsen, Marina Romero-Ramos
المصدر: Thomsen, M, Jacobsen, J, Lillethorup, T P, Schacht, A C, Simonsen, M I T, Romero-Ramos, M, Brooks, D J & Landau, A 2021, ' In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET ', Journal of Cerebral Blood Flow and Metabolism, vol. 41, no. 4, pp. 819-830 . https://doi.org/10.1177/0271678X20931140Test
J Cereb Blood Flow Metabمصطلحات موضوعية: Levetiracetam, Nerve Tissue Proteins, Pharmacology, Synaptic vesicle, Neuroprotection, Rats, Sprague-Dawley, Synapse, Lesion, Hydroxydopamines, 03 medical and health sciences, chemistry.chemical_compound, fluids and secretions, 0302 clinical medicine, synapse, In vivo, medicine, Animals, rat, Parkinson Disease, Secondary, 030304 developmental biology, SV2A, 0303 health sciences, Membrane Glycoproteins, Chemistry, Neurodegeneration, neurodegeneration, Original Articles, Quinolinic Acid, medicine.disease, Corpus Striatum, Rats, SV2A protein, Kinetics, Huntington Disease, Neuroprotective Agents, [11C]UCB-J PET, Neurology, Positron-Emission Tomography, Synapses, embryonic structures, Autoradiography, Anticonvulsants, Female, Neurology (clinical), Radiopharmaceuticals, medicine.symptom, Cardiology and Cardiovascular Medicine, 030217 neurology & neurosurgery, Quinolinic acid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d936e22954b72b8ef486a681c907b897Test
https://doi.org/10.1177/0271678x20931140Test -
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المؤلفون: Per Borghammer, Karen Østergaard, Peter Parbo, Arne Møller, Kristian Stær, David J. Brooks, Nicola Pavese, Alicia Garrido, Eduardo Tolosa, Morten Gersel Stokholm, Mónica Serradell, María José Martí, Alex Iranzo
المصدر: Stokholm, M G, Garrido, A, Tolosa, E, Serradell, M, Iranzo, A, Ostergaard, K, Borghammer, P, Moller, A, Parbo, P, Staer, K, Brooks, D J, Jose Marti, M & Pavese, N 2020, ' Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers ', Journal of Neurology, vol. 267, no. 8, pp. 2296-2300 . https://doi.org/10.1007/s00415-020-09830-3Test
Journal of Neurologyمصطلحات موضوعية: 0301 basic medicine, PENETRANCE, medicine.medical_specialty, Parkinson's disease, Neurology, Dopamine, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Asymptomatic, DISEASE, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Genetics, medicine, Humans, Movement disorders, Neuroinflammation, Subclinical infection, Original Communication, Microglia, business.industry, Parkinsonism, SYNUCLEINOPATHIES, Parkinson Disease, medicine.disease, nervous system diseases, PATHOLOGY, PET, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Clinical neurology, Mutation, Parkinson’s disease, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d9ae05a56f269dd603e6775f67cce3Test
https://doi.org/10.1007/s00415-020-09830-3Test -
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المؤلفون: Kathrine Stokholm, Majken B. Thomsen, Thea P. Lillethorup, Dariusz Orlowski, Jens Christian Sørensen, Ove Noer, Anna C. Schacht, David J. Brooks, Hamed Zaer, Trine Werenberg Mikkelsen, Andreas Nørgaard Glud, Erik Nielsen, Aage Kristian Olsen Alstrup, Michael Winterdahl, Anne M. Landau
مصطلحات موضوعية: medicine.medical_specialty, business.industry, MPTP, Dopaminergic, Asymptomatic, Cell loss, chemistry.chemical_compound, Text mining, Endocrinology, chemistry, Internal medicine, medicine, medicine.symptom, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::744f625987bdb45895bae68ed861ac10Test
https://doi.org/10.21203/rs.3.rs-620635/v1Test -
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المؤلفون: Karen Østergaard, Carles Gaig, David J. Brooks, Kristine Farmen, Eduardo Tolosa, Mónica Serradell, Per Borghammer, Kristina Bacher Svendsen, Alicia Garrido, Morten Gersel Stokholm, Marit Otto, Alex Iranzo, Sara K. Nissen, Arne Møller, Nicola Pavese, Joan Santamaria, Dolores Vilas, Marina Romero-Ramos
المصدر: Farmen, K, Nissen, S K, Stokholm, M G, Iranzo, A, Østergaard, K, Serradell, M, Otto, M, Svendsen, K B, Garrido, A, Vilas, D, Borghammer, P, Santamaria, J, Møller, A, Gaig, C, Brooks, D J, Tolosa, E, Pavese, N & Romero-Ramos, M 2021, ' Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 10, e2020858118 . https://doi.org/10.1073/pnas.2020858118Test
Proc Natl Acad Sci U S Aمصطلحات موضوعية: Male, Positron emission tomography, ALPHA-SYNUCLEIN, Inflammation, Substantia nigra, REM Sleep Behavior Disorder, REM sleep behavior disorder, Monocytes, Immune system, Neuroinflammation, PARKINSONS-DISEASE, medicine, Humans, TLR4, Aged, Neurons, Synucleinopathies, CD11b Antigen, Multidisciplinary, business.industry, Parkinsonism, Monocyte, HLA-DR Antigens, Biological Sciences, Middle Aged, medicine.disease, Substantia Nigra, Toll-Like Receptor 4, medicine.anatomical_structure, Positron-Emission Tomography, CELLS, Immunology, Female, CD163, medicine.symptom, monocytes, business, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2becded01064f4f976e0f987f5c183a5Test
https://doi.org/10.1073/pnas.2020858118Test -
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المؤلفون: D Hughes, Rainer Hinz, Anthony H.V. Schapira, Peter Parbo, Atul Mehta, Nicola Pavese, Stephen Mullin, David J. Brooks, Morten Gersel Stokholm
المصدر: Mullin, S, Stokholm, M G, Hughes, D, Mehta, A, Parbo, P, Hinz, R, Pavese, N, Brooks, D J & Schapira, A H V 2020, ' Brain Microglial Activation Increased in Glucocerebrosidase (GBA) Mutation Carriers without Parkinson's disease ', Movement Disorders . https://doi.org/10.1002/mds.28375Test
Mullin, S, Stokholm, M G, Hughes, D, Mehta, A, Parbo, P, Hinz, R, Pavese, N, Brooks, D J & Schapira, A H 2021, ' Brain Microglial Activation Increased in Glucocerebrosidase (GBA) Mutation Carriers without Parkinson's disease ', Movement Disorders, vol. 36, no. 3, pp. 774-779 . https://doi.org/10.1002/mds.28375Test
Movement Disordersمصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Parkinson's disease, positron emission tomography, microglia, Substantia nigra, Regular Issue Articles, Gene mutation, 03 medical and health sciences, 0302 clinical medicine, Hyposmia, Dopamine, Internal medicine, medicine, Humans, Neuroinflammation, business.industry, glucocerebrosidase, Brief Report, Brain, Parkinson Disease, medicine.disease, Penetrance, 030104 developmental biology, Endocrinology, Neurology, substantia nigra, Mutation, Glucosylceramidase, Brief Reports, Neurology (clinical), medicine.symptom, business, Glucocerebrosidase, 030217 neurology & neurosurgery, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8094805c5b2d2b943d326429467d4fTest
https://doi.org/10.1002/mds.28375Test -
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المؤلفون: Morten Gersel Stokholm, Rola Ismail, Simon Fristed Eskildsen, Hanne Gottrup, Allan K Hansen, Kim V. Hansen, David J. Brooks, Peter Parbo, Pernille L. Kjeldsen, Lasse Stensvig Madsen, Jeppe L. Schaldemose
المصدر: Ismail, R, Parbo, P, Madsen, L S, Hansen, A K, Hansen, K V, Schaldemose, J L, Kjeldsen, P L, Stokholm, M G, Gottrup, H, Eskildsen, S F & Brooks, D J 2020, ' The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease : a longitudinal PET study ', Journal of Neuroinflammation, vol. 17, no. 1, 151 . https://doi.org/10.1186/s12974-020-01820-6Test
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Journal of Neuroinflammationمصطلحات موضوعية: Male, 0301 basic medicine, MILD COGNITIVE IMPAIRMENT, Longitudinal study, Neurology, lcsh:RC346-429, 0302 clinical medicine, Neuroinflammation, Longitudinal Studies, BRAIN, TANGLES, Flortaucipir, medicine.diagnostic_test, Microglia, β-amyloid, General Neuroscience, beta-amyloid, Neurofibrillary Tangles, medicine.anatomical_structure, Positron emission tomography, Disease Progression, Cardiology, Female, medicine.symptom, MRI, PLAQUES, EXTRACTION, medicine.medical_specialty, Amyloid, PiB, Immunology, Prodromal Symptoms, tau Proteins, Inflammation, 03 medical and health sciences, Cellular and Molecular Neuroscience, POSITRON-EMISSION-TOMOGRAPHY, Alzheimer Disease, Internal medicine, Image Interpretation, Computer-Assisted, mental disorders, medicine, Humans, Cognitive Dysfunction, LOAD, Beta (finance), lcsh:Neurology. Diseases of the nervous system, Aged, PK11195, Amyloid beta-Peptides, business.industry, Research, MICROGLIAL ACTIVATION, MCI, PET, 030104 developmental biology, Positron-Emission Tomography, Alzheimer, Tau, business, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ed1916f133e151218ab5c6f47575b0Test
https://doi.org/10.1186/s12974-020-01820-6Test -
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المؤلفون: Rikke Beese Dalby, David J. Brooks, Rola Ismail, Rune Nielsen, Leif Østergaard, Peter Parbo, Hanne Gottrup, Hans Brændgaard, Simon Fristed Eskildsen, Anna Tietze
المصدر: Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Nielsen, R B, Parbo, P, Ismail, R, Dalby, R, Tietze, A, Brændgaard, H, Gottrup, H, Brooks, D J, Østergaard, L & Eskildsen, S F 2020, ' Impaired perfusion and capillary dysfunction in prodromal Alzheimer's disease ', Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, vol. 12, no. 1, e12032 . https://doi.org/10.1002/dad2.12032Test
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)مصطلحات موضوعية: capillary transit‐time heterogeneity, medicine.medical_specialty, positron emission tomography, neurovascular, prodromal, Precuneus, Neuroimaging, Blood volume, lcsh:Geriatrics, lcsh:RC346-429, 03 medical and health sciences, mild cognitive impairment, 0302 clinical medicine, Internal medicine, medicine, blood flow, magnetic resonance imaging, Dementia, lcsh:Neurology. Diseases of the nervous system, 030304 developmental biology, 0303 health sciences, medicine.diagnostic_test, hypoxia, business.industry, Neurodegeneration, amyloid, Magnetic resonance imaging, Blood flow, Hypoxia (medical), Alzheimer's, medicine.disease, lcsh:RC952-954.6, Psychiatry and Mental health, medicine.anatomical_structure, Cardiology, Neurology (clinical), medicine.symptom, business, Perfusion, 030217 neurology & neurosurgery, dementia
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e067b34cb29cd8b5a97ea9613ad42aTest
https://doi.org/10.1002/dad2.12032Test -
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المؤلفون: Rola Ismail, Kaj Blennow, David J. Brooks, Henrik Zetterberg, Peter Parbo, Lasse Stensvig Madsen, Thomas Vorup-Jensen, Simon Fristed Eskildsen
المصدر: Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-7 (2020)
Parbo, P, Madsen, L S, Ismail, R, Zetterberg, H, Blennow, K, Eskildsen, S F, Vorup-Jensen, T & Brooks, D J 2020, ' Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease ', Alzheimer's Research & Therapy, vol. 12, no. 1, 3 . https://doi.org/10.1186/s13195-019-0574-0Testمصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Neurology, Precuneus, lcsh:RC346-429, 0302 clinical medicine, Cerebrospinal fluid, Neurofilament Proteins, Carbon Radioisotopes, Microglia, medicine.diagnostic_test, biology, Middle Aged, Magnetic Resonance Imaging, medicine.anatomical_structure, Female, medicine.symptom, medicine.medical_specialty, Neurofilament light, Cognitive Neuroscience, Prodromal Symptoms, Inflammation, Neuroprotection, lcsh:RC321-571, 03 medical and health sciences, Alzheimer Disease, medicine, Translocator protein, Humans, Cognitive Dysfunction, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, lcsh:Neurology. Diseases of the nervous system, Aged, PK11195, business.industry, Research, Magnetic resonance imaging, Isoquinolines, MCI, 030104 developmental biology, PET, Positron-Emission Tomography, biology.protein, Alzheimer, Neurology (clinical), Radiopharmaceuticals, business, 030217 neurology & neurosurgery, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6a0deb927dcc81eeef293d7bb0d6c7Test
http://europepmc.org/articles/PMC6941285Test
