نتائج البحث - "Önder Yildirim"

1

A drug screen with approved compounds identifies amlexanox as a novel Wnt/beta-catenin activator inducing lung epithelial organoid formation

المؤلفون: Martina M. De Santis, Ina Rothenaigner, Monica Campillos, Melanie Königshoff, Kamyar Hadian, Ali Önder Yildirim, Mareike Lehmann, Ali Doryab, Hoeke A. Baarsma, Darcy E. Wagner, Xueping Liu, Otmar Schmid, Rita Costa, Kenji Schorpp

المساهمون: Groningen Research Institute for Asthma and COPD (GRIAC)

المصدر: British Journal of Pharmacology, 178(19), 4026-4041. Wiley-Blackwell
Br. J. Pharmacol. 178, 4026-4041 (2021)

مصطلحات موضوعية: TBK1, Aminopyridines, regenerative medicine, HEPATOCYTE GROWTH-FACTOR, chronic obstructive pulmonary disease, Mice, In vivo, REGENERATION, medicine, Organoid, Organoids, Regenerative Medicine, Wnt/β-catenin Signaling Pathway, Amlexanox, Chronic Obstructive Pulmonary Disease, Emphysema, Animals, COPD, Luciferase, Lung, Wnt Signaling Pathway, beta Catenin, organoids, Pharmacology, REPAIR, Chemistry, amlexanox, IKK-EPSILON, Wnt signaling pathway, PLATFORM, respiratory system, CONCISE GUIDE, respiratory tract diseases, APOPTOSIS, Mice, Inbred C57BL, emphysema, Mechanism of action, Pharmaceutical Preparations, Catenin, Cancer research, UPDATE, Wnt/beta-catenin signalling pathway, medicine.symptom, Ex vivo, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52de4eaeaca13ea80f024fc17ff04a91Test
https://research.rug.nl/en/publications/dac3e8a9-8845-4eee-b4cc-2bf9a66fe19cTest

2

TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema

المؤلفون: Johann Schredelseker, Jonas Weber, Yu-Kai Chao, Ali Önder Yildirim, Christian Schremmer, Christian Grimm, Martina Kannler, Thomas Gudermann, Suhasini Rajan, Gabriela Krasteva-Christ, Norbert Weissmann, Monika Brosien, Alexander Dietrich

المصدر: JCI Insight
JCI Insight, Vol 5, Iss 20 (2020)
JCI insight 5:e134464 (2020)

مصطلحات موضوعية: Lung Diseases, 0301 basic medicine, TRPV4, Pulmonology, Endothelium, Cell, TRPV Cation Channels, Calcium Channels, Cell Biology, Ion Channels, Pharmacology, Bronchi, Mice, 03 medical and health sciences, Transient receptor potential channel, 0302 clinical medicine, Cell Movement, Leucine, Edema, medicine, Animals, Humans, Barrier function, Mice, Knockout, Sulfonamides, Voltage-dependent calcium channel, Chemistry, General Medicine, respiratory system, Molecular biology, Aquaporin 5, Disease Models, Animal, Calcium channels, 030104 developmental biology, medicine.anatomical_structure, Alveolar Epithelial Cells, Reperfusion Injury, Ion channels, 030220 oncology & carcinogenesis, Medicine, medicine.symptom, Ex vivo, Lung Transplantation, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1a6d0ec2d338adf9cf72fca54adeccTest
https://doi.org/10.1172/jci.insight.134464Test

3

LSC - 2019 - Relevant murine model to study the development of COPD pathogenesis in smokers with viral infections

المؤلفون: Ali Önder Yildirim, Susanne Krauss-Etschmann, Natalia El-Merhie, Heinz Fehrenbach, Sebastian Reuter, Martin A. Wolff, Torsten Goldmann

المصدر: Airway cell biology and immunopathology.

مصطلحات موضوعية: COPD, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Inflammation, Lipocalin, medicine.disease, respiratory tract diseases, Pathogenesis, Transcriptome, Cytokine, Bronchoalveolar lavage, Immunology, medicine, medicine.symptom, Risk factor, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c5149755994435ceae19d022a3ca66e5Test
https://doi.org/10.1183/13993003.congress-2019.pa2408Test

4

Transient receptor vanilloid 4 (TRPV4) channels are essential for alveolar epithelial cell function

المؤلفون: Johann Schredelseker, Norbert Weissmann, Gabriela Krasteva-Christ, Monika Brosien, Ali Önder Yildirim, Alexander Dietrich, Yu-Kai Chao, Thomas Gudermann, Suhasini Rajan, Jonas Weber, Christian Grimm, Martina Kannler

مصطلحات موضوعية: TRPV4, Lung, Endothelium, Chemistry, Surfactant protein C, respiratory system, Cell biology, Transient receptor potential channel, medicine.anatomical_structure, Edema, medicine, medicine.symptom, Barrier function, Corneal epithelium

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fb8445347d894ea844c1f0b30c92adTest
https://doi.org/10.1101/775668Test

5

TRPA1 channels: expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia

المؤلفون: Dirk Steinritz, Robin Lüling, Ali Önder Yildirim, Thomas Gudermann, Martina Kannler, Alexander Dietrich

المصدر: Pflügers Archiv - European Journal of Physiology. 470:1231-1241

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35f3342858d83cee99fdeea69da4b32Test
https://doi.org/10.1007/s00424-018-2148-6Test

6

Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice

المؤلفون: Zhe Zhou-Suckow, Oliver Eickelberg, Thomas M. Conlon, Jie Jia, Carolina Ballester Lopez, Mariola Bednorz, Ali Önder Yildirim, Marcus A. Mall, Norbert Weissmann, Michael Seimetz

المصدر: Am. J. Physiol. Lung Cell Mol. Physiol. 311, L602-L610 (2016)

مصطلحات موضوعية: Male, 0301 basic medicine, Pulmonary and Respiratory Medicine, Pathology, medicine.medical_specialty, Physiology, Mice, Transgenic, Inflammation, Respiratory Mucosa, Airways Disease, Cigarette Smoke, Mucus, Newborn, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, Smoke, Physiology (medical), Tobacco, medicine, Animals, Lung, medicine.diagnostic_test, business.industry, Smoking, Cell Biology, respiratory system, medicine.disease, Neutrophilia, Obstructive lung disease, respiratory tract diseases, Mice, Inbred C57BL, CXCL1, 030104 developmental biology, Bronchoalveolar lavage, medicine.anatomical_structure, Animals, Newborn, Immunology, Airway Remodeling, Female, medicine.symptom, Airway, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d857143e0ad3f7af8d9124eeaa82b36Test
https://doi.org/10.1152/ajplung.00124.2016Test

7

The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease

المؤلفون: Oliver Eickelberg, Carolina Ballester‐López, Isis E. Fernandez, Zeynep Ertüz, Martin Irmler, Ali Önder Yildirim, Thomas M. Conlon, Stijn E. Verleden, Johannes Beckers, Flavia R. Greiffo

المصدر: EBioMedicine 43, 562-575 (2019)
EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, Research paper, NF-KAPPA-B, Fluorescent Antibody Technique, Gene Expression, EMPHYSEMA, Research & Experimental Medicine, Monocytes, ACTIVATION, Mice, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Macrophage, ALVEOLAR MACROPHAGES, Lung, Mice, Knockout, COPD, Receptors, Notch, Cigarette smoke, General Medicine, medicine.anatomical_structure, DNER, Medicine, Research & Experimental, 030220 oncology & carcinogenesis, Notch signalling, SIGNALING PATHWAY, medicine.symptom, Life Sciences & Biomedicine, Signal Transduction, EXPRESSION, DEFENSE, Notch signaling pathway, Inflammation, Nerve Tissue Proteins, Receptors, Cell Surface, IFN gamma, Models, Biological, General Biochemistry, Genetics and Molecular Biology, NFkB, MECHANISMS, Immunophenotyping, 03 medical and health sciences, Interferon-gamma, Medicine, General & Internal, Immunity, General & Internal Medicine, medicine, Animals, Humans, Secretion, Science & Technology, INTERFERON-GAMMA, RECEPTOR, business.industry, Microarray analysis techniques, Macrophages, Macrophage Activation, medicine.disease, respiratory tract diseases, Disease Models, Animal, 030104 developmental biology, Copd, Dner, Notch Signalling, Ifn Gamma, Cigarette Smoke, Nfkb, Cancer research, Human medicine, business, Biomarkers

وصف الملف: application/pdf; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b166c725ded5788b3bb57659385902Test
https://europepmc.org/articles/PMC6562022Test/

8

Relevant murine model to study the development of COPD pathogenesis in smokers with viral infections

المؤلفون: Heinz Fehrenbach, Martin A. Wolff, Sebastian Reuter, Susanne Krauss-Etschmann, Ali Önder Yildirim, Natalia El-Merhie, Torsten Goldmann

المصدر: Airway Cell Biology and Immunopathology.

مصطلحات موضوعية: COPD, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Inflammation, Lipocalin, medicine.disease, respiratory tract diseases, Pathogenesis, Transcriptome, Bronchoalveolar lavage, Cytokine, Immunology, medicine, medicine.symptom, Risk factor, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ce4bcb1c6de697b1aa439abb8bbfefeeTest
https://doi.org/10.1183/23120541.lungscienceconference-2019.pp109Test

9

2D cross-omics integrated enrichment analysis reveals insights into COPD pathogenesis

المؤلفون: Ali Önder Yildirim, Fabian J. Theis, Oliver Eickelberg, Jan Krumsiek, Jörg Bartel, Julian Dorer, Martina Häckl, Thomas M. Conlon

المصدر: Airway Cell Biology and Immunopathology.

مصطلحات موضوعية: COPD, business.industry, Inflammation, medicine.disease, Bioinformatics, Proteomics, Omics, Transcriptome, Pathogenesis, medicine, medicine.symptom, business, Pathological, Small Airway Remodeling

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::734ceef2be329e9d9651b6c4909b74a5Test
https://doi.org/10.1183/1393003.congress-2017.oa291Test

10

Inflammaging increases susceptibility to cigarette smoke-induced COPD

المؤلفون: Gerrit John-Schuster, Ali Önder Yildirim, Oliver Eickelberg, Stefanie Günter, Katrin Hager, Thomas M. Conlon

المصدر: Oncotarget 7, 30068-30083 (2016)
Oncotarget

مصطلحات موضوعية: 0301 basic medicine, T-Lymphocytes, Cell Count, Pulmonary compliance, Lymphocyte Activation, Pathogenesis, Mice, Pulmonary Disease, Chronic Obstructive, Research Paper: Gerotarget (Focus on Aging), iBALT, Smoke, Lung, Lung Compliance, COPD, B-Lymphocytes, Gerotarget, cigarette smoke, Smoking, Age Factors, Pathophysiology, Specific Pathogen-Free Organisms, medicine.anatomical_structure, Oncology, Chronic inflammatory response, Airway Remodeling, Female, Disease Susceptibility, medicine.symptom, Bronchoalveolar Lavage Fluid, medicine.medical_specialty, Inflammation, 03 medical and health sciences, Immune system, Internal medicine, Tobacco, medicine, Animals, Humans, B cells, business.industry, aging, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, Immunology, B Cells, Copd, Aging, Cigarette Smoke, Ibalt, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b7f85ed8b2719d7a75c7a633d1bcf8Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=45500Test

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