المؤلفون: Elena Kostromina, Christoffer Nord, Tomas Alanentalo, Federico Morini, Per Olof Berggren, Yan Xiong, Erwin Ilegems, Jürgen Mayer, Pim P van Krieken, James Sharpe, Ulf Ahlgren, Teresa Pereira, Maria Eriksson, Jorge L. Ruas, Max Hahn

المصدر: Communications Biology, Vol 3, Iss 1, Pp 1-14 (2020)
Communications Biology

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system diseases, Cell- och molekylärbiologi, Cell, Medicine (miscellaneous), Optical imaging, Mice, 0302 clinical medicine, 3-D reconstruction, Insulin-Secreting Cells, Insulin, lcsh:QH301-705.5, Glucose Transporter Type 2, Microscopy, Confocal, geography.geographical_feature_category, biology, Diabetes, Islet, Experimental models of disease, Mechanisms of disease, medicine.anatomical_structure, Endokrinologi och diabetes, General Agricultural and Biological Sciences, medicine.drug, endocrine system, medicine.medical_specialty, Down-Regulation, 030209 endocrinology & metabolism, Endocrinology and Diabetes, Article, General Biochemistry, Genetics and Molecular Biology, Diabetes Mellitus, Experimental, Islets of Langerhans, 03 medical and health sciences, Microscopy, Electron, Transmission, Downregulation and upregulation, Internal medicine, Diabetes mellitus, medicine, Animals, geography, Glucose transporter, nutritional and metabolic diseases, medicine.disease, Streptozotocin, Mice, Inbred C57BL, Transplantation, 030104 developmental biology, Endocrinology, Microscopy, Fluorescence, lcsh:Biology (General), biology.protein, GLUT2, Cell and Molecular Biology, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba990408233453663d8fd8eb4c76959Test
http://link.springer.com/article/10.1038/s42003-020-01243-2Test

المؤلفون: Tomas Alanentalo, Nils Langeland Johansen, Jens Buchardt, Knud Vad, Peter Thygesen, Prafull S. Gandhi, Johannes Josef Fels, Maj Petersen, Peter Helding-Kvist

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1181 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 4

مصطلحات موضوعية: Male, Models, Molecular, 0301 basic medicine, Fluorescence-lifetime imaging microscopy, Growth hormone receptor, Rats, Sprague-Dawley, lcsh:Chemistry, Mice, Pharmaceutical Sciences, 0302 clinical medicine, Tissue Distribution, lcsh:QH301-705.5, Cells, Cultured, Spectroscopy, Chemistry, General Medicine, Human serum albumin, Computer Science Applications, proximal epiphysis, human growth hormone, Female, medicine.drug, medicine.medical_specialty, Biodistribution, receptor signaling, Mice, Nude, 030209 endocrinology & metabolism, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, In vivo, Internal medicine, P-STAT5 activation, medicine, Animals, Humans, Distribution (pharmacology), fluorescence molecular tomography, Physical and Theoretical Chemistry, Molecular Biology, biodistribution, Organic Chemistry, Isothermal titration calorimetry, Receptors, Somatotropin, Farmaceutiska vetenskaper, light-sheet fluorescence microscopy, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, somapacitan, p-stat5 activation, Hepatocytes, Ex vivo

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7858fd82c1582eb0b5f986f6b7db2a5fTest
https://www.mdpi.com/1422-0067/21/4/1181Test

المؤلفون: Tess Tsai Hsiu Lu, Kasper Marstal, Lotte Bjerre Knudsen, Knut Conradsen, Casper Gravesen Salinas, Anders Bjorholm Dahl, Jacob Hecksher-Sørensen, Sanaz Gabery, Anna Secher, Aaron J. Mercer, Tomas Alanentalo, Anda Cornea

المساهمون: Medical Informatics, Radiology & Nuclear Medicine

المصدر: Salinas, C B G, Lu, T T H, Gabery, S, Marstal, K, Alanentalo, T, Mercer, A J, Cornea, A, Conradsen, K, Hecksher-Sørensen, J, Dahl, A B, Knudsen, L B & Secher, A 2018, ' Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment ', Scientific Reports, vol. 8, no. 1, 10310 . https://doi.org/10.1038/s41598-018-28496-6Test
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports, 8:10310. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, Nervous system, Computer science, Central nervous system, Hypothalamus, lcsh:Medicine, Nervous System, Brain mapping, Article, Glucagon-Like Peptide-1 Receptor, Eating, Mice, 03 medical and health sciences, medicine, Animals, Hypoglycemic Agents, Lateral parabrachial nucleus, lcsh:Science, Brain Mapping, Multidisciplinary, Computational neuroscience, Liraglutide, Brain atlas, lcsh:R, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Microscopy, Fluorescence, Light sheet fluorescence microscopy, lcsh:Q, Brainstem, Proto-Oncogene Proteins c-fos, Neuroscience, Brain Stem, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702f32f44771f707e197f3cd05ced199Test
https://orbit.dtu.dk/en/publications/6bc1039c-723b-4b61-b42f-1a2e139eb81eTest

المؤلفون: Rasmus Wernersson, Fredrik Wolfhagen Sand, Charlotte Helgstrand, Kevin Dalgaard, Jacob Hald, Anne Grapin-Botton, Sven Hastrup, Thomas Frogne, Jonas Ahnfelt-Rønne, Ole D. Madsen, Lena Hansson, Erik Vernet, Mark Kalisz, Dennis Madsen, Tomas Alanentalo, Mads Grønborg, Maja Borup Kjær Petersen, Fredrik Kryh Öberg, Michael Paolo Bastner Sandrini, Annette Plesner, Claude Rescan, Christian Honoré, Philippe Ravassard, Carsten Jessen, Louise Winkel, Camilla Ingvorsen, Xenia Asbæk Wolf, Hanni Willenbrock, Jan N. Jensen, Anna Kirstine Ringgaard, Christine Bruun, Violeta Georgieva Tsonkova, Jacob Hecksher-Sørensen, Johannes Josef Fels, Lars Groth Grunnet, Allan Christian Shaw

المساهمون: University of Copenhagen = Københavns Universitet (KU), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Molecular metabolism
Molecular metabolism, Elsevier, 2018, 8, pp.144-157. ⟨10.1016/j.molmet.2017.12.007⟩
Molecular Metabolism
Molecular Metabolism, Vol 8, Iss, Pp 144-157 (2018)
Tsonkova, V G, Sand, F W, Wolf, X A, Grunnet, L G, Ringgaard, A K, Ingvorsen, C, Winkel, L, Kalisz, M, Dalgaard, K, Bruun, C, Fels, J J, Helgstrand, C, Hastrup, S, Öberg, F K, Vernet, E, Sandrini, M P B, Shaw, A C, Jessen, C, Grønborg, M, Hald, J, Willenbrock, H, Madsen, D, Wernersson, R, Hansson, L, Jensen, J N, Plesner, A, Alanentalo, T, Petersen, M B K, Grapin-Botton, A, Honoré, C, Ahnfelt-Rønne, J, Hecksher-Sørensen, J, Ravassard, P, Madsen, O D, Rescan, C & Frogne, T 2018, ' The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates ', Molecular Metabolism, vol. 8, pp. 144-157 . https://doi.org/10.1016/j.molmet.2017.12.007Test

مصطلحات موضوعية: 0301 basic medicine, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, SI, Stimulation index, medicine.medical_treatment, EndoC-βH1, Proliferation, Cell Culture Techniques, Drug Evaluation, Preclinical, Mice, SCID, CytMix, Cytokine mixture, Mice, 0302 clinical medicine, Insulin-Secreting Cells, Insulin Secretion, Cells, Cultured, Chemistry, Bxv1, B10 xenotropic virus 1, EdU, 5-ethynyl-2′-deoxyuridine, 3. Good health, Cell biology, Cytokine, Original Article, Beta cell, Glucose stimulated insulin secretion, medicine.drug, lcsh:Internal medicine, Somatostatin signaling, Incretin, GSIS, Glucose stimulated insulin secretion, 030209 endocrinology & metabolism, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Cell Line, Diabetes Mellitus, Experimental, 03 medical and health sciences, GLP1R, GLP1 receptor, PACAP, Pituitary Adenylate Cyclase-Activating Polypeptides, medicine, Animals, Humans, Hypoglycemic Agents, Pseudoislets, lcsh:RC31-1245, sXBP1, spliced XBP1, Molecular Biology, IPGTT, Intraperitoneal glucose tolerance test, Insulin, SST, Somatostatin, BB, Bombesin, STZ, Streptozotocin, Cell Biology, Streptozotocin, SSTR, Somatostatin receptor, SEM, Standard error of the mean, 030104 developmental biology, Cell culture, Apoptosis, Unfolded protein response, Ex4, Exendin-4

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb3e641ee305f9db5f81e09f4ed88e7Test
https://hal.sorbonne-universite.fr/hal-02018209/documentTest