المؤلفون: Rene Gonzalez, Adil Daud, Ming Yin, Omid Hamid, Peter D. Boasberg, Karl D. Lewis, Anna C. Pavlick, Luna Musib, Igor Puzanov, Grant A. McArthur, Theodore F. Logan, Damien Kee, Thomas F. Gajewski, Antoni Ribas, Lawrence E. Flaherty, Iris T. Chan, Bartosz Chmielowski, Nicholas Choong

المصدر: The Lancet Oncology. 15:954-965

مصطلحات موضوعية: Male, Indoles, Skin Neoplasms, Pharmacology, Gastroenterology, chemistry.chemical_compound, Piperidines, Medicine, Prospective Studies, Infusions, Intravenous, Vemurafenib, Melanoma, Sulfonamides, MEK inhibitor, Middle Aged, Rash, Survival Rate, Treatment Outcome, Oncology, Drug Therapy, Combination, Female, medicine.symptom, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Maximum Tolerated Dose, Risk Assessment, Disease-Free Survival, Drug Administration Schedule, Internal medicine, Humans, Neoplasm Invasiveness, Adverse effect, Protein Kinase Inhibitors, Survival rate, Aged, Neoplasm Staging, Cobimetinib, Dose-Response Relationship, Drug, business.industry, Patient Selection, Dabrafenib, medicine.disease, chemistry, Mutation, Azetidines, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f37e6205efc353876207a88d307180Test
https://doi.org/10.1016/s1470-2045Test(14)70301-8

المؤلفون: Mark J. Dresser, Iris T. Chan, Edna F. Choo, Isabelle Rooney, Luna Musib, Yuzhong Deng, Steve Eppler

المصدر: Molecular Pharmaceutics. 10:4046-4054

مصطلحات موضوعية: Adult, Male, Drug, Absorption (pharmacology), medicine.drug_class, media_common.quotation_subject, Cmax, Rabeprazole, Administration, Oral, Biological Availability, Pharmaceutical Science, Proton-pump inhibitor, Pharmacology, Absorption, Young Adult, chemistry.chemical_compound, Piperidines, Drug Discovery, medicine, Humans, media_common, Cobimetinib, Molecular Structure, Chemistry, Proton Pump Inhibitors, Hydrogen-Ion Concentration, Middle Aged, Drug interaction, Bioavailability, Food, Azetidines, Molecular Medicine, Female, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52f3843b73b39bdd612661047c8a741Test
https://doi.org/10.1021/mp400383xTest

المؤلفون: Junko Aimi, Steven Gendreau, Peter Schmid, Ian E. Krop, Meng Chen, Stephen T. Johnston, Mark R. Lackner, Garret Hampton, Mika K. Derynck, Kimberly Walter, Jiaheng Qiu, Lukas C. Amler, Heidi Savage, Timothy R. Wilson, Iris T. Chan, Jill M. Spoerke

المصدر: Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)

مصطلحات موضوعية: 0301 basic medicine, Oncology, DNA Mutational Analysis, General Physics and Astronomy, Drug resistance, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Breast, skin and connective tissue diseases, Fulvestrant, Aged, 80 and over, Sulfonamides, Multidisciplinary, Estradiol, DNA, Neoplasm, Middle Aged, Metastatic breast cancer, 030220 oncology & carcinogenesis, Female, medicine.drug, Adult, medicine.medical_specialty, Indazoles, medicine.drug_class, Class I Phosphatidylinositol 3-Kinases, Science, Breast Neoplasms, General Biochemistry, Genetics and Molecular Biology, Article, Disease-Free Survival, 03 medical and health sciences, Internal medicine, medicine, Humans, Clinical significance, Allele frequency, Protein Kinase Inhibitors, Aged, Aromatase inhibitor, business.industry, Estrogen Receptor alpha, Estrogens, General Chemistry, medicine.disease, Clinical trial, body regions, 030104 developmental biology, Endocrinology, Drug Resistance, Neoplasm, Mutation, Estrogen Receptor Antagonists, business, Estrogen receptor alpha

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9793ee4d0117eafc5f817a18176c60Test
http://europepmc.org/articles/PMC4869259Test

المؤلفون: Susan S. Huang, Lindsey R. Baden, Richard Stone, Iris T. Chan

المصدر: Huang, SS; Chan, IT; Stone, RM; & Baden, LR. (2002). Successful treatment of angioinvasive aspergillosis during prolonged neutropenia with liposomal amphotericin, voriconazole, and caspofungin. Infectious Diseases in Clinical Practice, 11(6), 355-358. doi: 10.1097/01.idc.0000078754.71576.ce. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8ts5f2sjTest

مصطلحات موضوعية: Microbiology (medical), Voriconazole, medicine.medical_specialty, business.industry, Neutropenia, Aspergillosis, medicine.disease, Gastroenterology, chemistry.chemical_compound, Infectious Diseases, chemistry, Internal medicine, medicine, Liposomal amphotericin, Caspofungin, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb7288dba25d705db44360b4b7351ccTest
https://doi.org/10.1097/01.idc.0000078754.71576.ceTest

المؤلفون: Steven Gendreau, Stephen T. Johnston, Ian E. Krop, Mika K. Derynck, J Qui, Peter Schmid, Kimberly Walter, G. Hampton, Lukas C. Amler, Mark R. Lackner, Jill M. Spoerke, Iris T. Chan

المصدر: Cancer Research. 76:PD6-03

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Pathology, medicine.drug_class, Luma, Phases of clinical research, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, medicine, Digital polymerase chain reaction, Allele frequency, Aromatase inhibitor, Fulvestrant, business.industry, medicine.disease, body regions, 030104 developmental biology, 030220 oncology & carcinogenesis, business, Estrogen receptor alpha, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a043109642edc056cb6c72ccb8e4db08Test
https://doi.org/10.1158/1538-7445.sabcs15-pd6-03Test

المؤلفون: Iris T. Chan, D. Gary Gilliland

المصدر: Cell Cycle. 3:534-535

مصطلحات موضوعية: Regulation of gene expression, medicine.drug_class, Histone deacetylase inhibitor, Promoter, Cell Biology, Biology, Virology, Chromatin, Histone, Cell culture, Gene expression, medicine, Cancer research, biology.protein, Molecular Biology, Vorinostat, Developmental Biology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::36cdefac349c9183b65f4a5b159319c0Test
https://doi.org/10.4161/cc.3.5.827Test

المؤلفون: M.S.L. Teng, Adil Daud, Rene Gonzalez, Grant A. McArthur, Thomas F. Gajewski, Anna C. Pavlick, Igor Puzanov, Iris T. Chan, A. Ribas, Nicholas Choong

المصدر: Annals of Oncology. 23:ixe19

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Nausea, business.industry, Melanoma, Hematology, medicine.disease, Rash, Discontinuation, Tolerability, Internal medicine, medicine, Liver function, medicine.symptom, Adverse effect, business, Vemurafenib, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a085286d002e016cacaef77df937967cTest
https://doi.org/10.1016/s0923-7534Test(20)34336-2