نتائج البحث - "Francisco Morís"

1

The SRC Inhibitor Dasatinib Induces Stem Cell-Like Properties in Head and Neck Cancer Cells that are Effectively Counteracted by the Mithralog EC-8042

المؤلفون: Francisco Hermida-Prado, Francisco Morís, Laura Santos, Rocío Granda-Díaz, Jhudit Pérez-Escuredo, Rene Rodriguez, M. Ángeles Villaronga, Juan P. Rodrigo, Luis M. Montuenga, Eva Allonca, Juana M. García-Pedrero, Rocío Fuente, Nagore Del-Río-Ibisate, Maria Ana Hermosilla, Jackeline Agorreta, Juan Tornin, Irati Garmendia, Patricia Oro

المصدر: Journal of Clinical Medicine; Volume 8; Issue 8; Pages: 1157
Journal of Clinical Medicine, Vol 8, Iss 8, p 1157 (2019)
Journal of Clinical Medicine
WOS:000483737700057
RUO. Repositorio Institucional de la Universidad de Oviedo
instname

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a83bb6b1215e278f5b57e50350187bTest

2

Chemoenzymatic Approaches to the Synthesis of the Calcimimetic Agent Cinacalcet Employing Transaminases and Ketoreductases

المؤلفون: Fernando López-Gallego, Javier González-Sabín, Nicolás Ríos-Lombardía, Lisa Marx, Judith E. Farnberger, Wolfgang Kroutil, Francisco Morís, Ana I. Benítez-Mateos, Per Berglund

المصدر: Advanced Synthesis & Catalysis

مصطلحات موضوعية: chemistry.chemical_classification, Ketone, Cinacalcet, 010405 organic chemistry, Enantioselective synthesis, General Chemistry, Alkylation, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Turnover number, Enantiopure drug, chemistry, Biocatalysis, medicine, Amination, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ddc3b3b5329ac9f4731e978fb2e629Test
https://doi.org/10.1002/adsc.201701485Test

3

The multikinase inhibitor EC-70124 synergistically increased the antitumor activity of doxorubicin in sarcomas

المؤلفون: Carlos Alvarez-Fernandez, Paula Costales, Juan Tornin, Lucia Fernandez-Nevado, Francisco Morís, Laura Santos, Patricia Oro, Aida Rodríguez, Maria Ana Hermosilla, Veronica Rey, María Teresa Fernández-García, Jhudit Pérez-Escuredo, Sofía T. Menéndez, Alejandro Braña, Oscar Estupiñan, Aurora Astudillo, Eva Allonca, Rene Rodriguez

المساهمون: Universitat Politècnica de Catalunya. Departament de Ciència dels Materials i Enginyeria Metal·lúrgica

المصدر: Recercat. Dipósit de la Recerca de Catalunya
instname
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo

مصطلحات موضوعية: Cancer Research, Cell cycle checkpoint, Carbazoles, Mice, SCID, Enginyeria dels materials [Àrees temàtiques de la UPC], Tumors--Treatment, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, In vivo, Mice, Inbred NOD, Antineoplastic Combined Chemotherapy Protocols, medicine, Tumor Cells, Cultured, Animals, Humans, Doxorubicin, Midostaurin, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Tumors -- Tractament, Kinase, Chemistry, Cancer--Treatment, TOR Serine-Threonine Kinases, Drug Synergism, Sarcoma, Staurosporine, Xenograft Model Antitumor Assays, Oncology, 030220 oncology & carcinogenesis, Cancer research, ATP-Binding Cassette Transporters, Female, Càncer -- Tractament, Proto-oncogene tyrosine-protein kinase Src, medicine.drug, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459e877b0384337f68ba47f23f7d302fTest
https://pubmed.ncbi.nlm.nih.gov/30575954Test

4

EC-70124, a Novel Glycosylated Indolocarbazole Multikinase Inhibitor, Reverts Tumorigenic and Stem Cell Properties in Prostate Cancer by Inhibiting STAT3 and NF-κB

المؤلفون: Francisco Morís, Domenico Albino, Cristina García Inclán, Luz Elena Núñez, Cecilia Dallavalle, Giuseppina M. Carbone, Nicole Longoni, Paula Costales, Carlo V. Catapano, Gianluca Civenni

المصدر: Molecular Cancer Therapeutics. 15:806-818

مصطلحات موضوعية: Male, STAT3 Transcription Factor, 0301 basic medicine, Cancer Research, Glycosylation, Antineoplastic Agents, Apoptosis, Pharmacology, Mice, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Cancer stem cell, Prostate, Cell Line, Tumor, medicine, Animals, Humans, Staurosporine, STAT3, Protein Kinase Inhibitors, Transcription factor, Cell Proliferation, biology, Cell Cycle, NF-kappa B, Prostatic Neoplasms, Cell cycle, medicine.disease, Xenograft Model Antitumor Assays, Tumor Burden, Disease Models, Animal, Cell Transformation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, biology.protein, Cancer research, Stem cell, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e707f716755d5eba02662d41b4e8396Test
https://doi.org/10.1158/1535-7163.mct-15-0791Test

5

Cytotoxic effects of mithramycin DIG-MSK can depend on the rise of autophagy

المؤلفون: Luz Elena Núñez, Francisco Morís, Maria A. Rodríguez-Sánchez, José Portugal, Carolina Vizcaíno

المساهمون: European Commission, Generalitat de Catalunya, Ministerio de Ciencia e Innovación (España)

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
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مصطلحات موضوعية: Cell death, Cell type, Programmed cell death, Antineoplastic Agents, Apoptosis, HCT116 cells, Deoxyglucose, Biology, Toxicology, Mithramycin, Cell Line, Tumor, Autophagy, medicine, Humans, Cytotoxic T cell, Ovarian Neoplasms, Plicamycin, General Medicine, Cell cycle, Cell biology, Gene Expression Regulation, Neoplastic, Cell culture, Colonic Neoplasms, A2780 cells, Female, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1867520e29a95b8911357f8b2f759afaTest
https://doi.org/10.1016/j.tiv.2015.06.008Test

6

The chromomycin CmmA acetyltransferase: a membrane-bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

المؤلفون: Luz Elena Núñez, Francisco Morís, Carmen Méndez, Javier González-Sabín, Beatriz García, Alfredo F. Braña, Nuria Menéndez, José A. Salas

المصدر: Microbial Biotechnology. 4:226-238

مصطلحات موضوعية: Plicamycin, Glycosylation, Bioengineering, Acetyltransferases, Biology, biology.organism_classification, Applied Microbiology and Biotechnology, Biochemistry, chemistry.chemical_compound, Biosynthesis, chemistry, Acetylation, Cell culture, Acetyltransferase, medicine, Streptomyces griseus, Biotechnology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8b5d7f1d0c09f1c7c2d8c723b807f48eTest
https://doi.org/10.1111/j.1751-7915.2010.00229.xTest

7

Front Cover Picture: Chemoenzymatic Approaches to the Synthesis of the Calcimimetic Agent Cinacalcet Employing Transaminases and Ketoreductases (Adv. Synth. Catal. 11/2018)

المؤلفون: Ana I. Benítez-Mateos, Lisa Marx, Nicolás Ríos-Lombardía, Wolfgang Kroutil, Fernando López-Gallego, Per Berglund, Javier González-Sabín, Judith E. Farnberger, Francisco Morís

المصدر: Advanced Synthesis & Catalysis. 360:2061-2061

مصطلحات موضوعية: Cinacalcet, Front cover, Calcimimetic agent, Chemistry, medicine, Enantioselective synthesis, General Chemistry, Combinatorial chemistry, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2fd14abc5bcfdfe3b40d03a12488c804Test
https://doi.org/10.1002/adsc.201800499Test

8

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer

المؤلفون: Luz Elena Núñez, Atanasio Pandiella, Alberto Ocaña, Mónica Gómez-Juárez, Gary D. Bader, Maria Jose Gascon-Escribano, Verónica Corrales-Sánchez, Maria D. Cuenca-Lopez, Jorge Morales, Juan Carlos Montero, Gemma Serrano-Heras, Veronique Voisin, Francisco Morís

المساهمون: Fundación CRIS contra el Cáncer, Asociación Española Contra el Cáncer, Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España)

المصدر: Oncotarget
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Epithelial-Mesenchymal Transition, Rebeccamycin, Blotting, Western, Antineoplastic Agents, Apoptosis, Triple Negative Breast Neoplasms, ComputingMilieux_LEGALASPECTSOFCOMPUTING, Biology, Mice, Breast cancer, Cell Movement, Cell Line, Tumor, medicine, Staurosporine, Animals, Humans, Protein Kinase Inhibitors, Triple-negative breast cancer, PI3K/AKT/mTOR pathway, Cell Proliferation, Oligonucleotide Array Sequence Analysis, EC-70124, Mice, Inbred BALB C, Kinase inhibitor, Kinase, Cell growth, Reverse Transcriptase Polymerase Chain Reaction, Cancer, medicine.disease, Molecular biology, Immunohistochemistry, Xenograft Model Antitumor Assays, Oncology, Cancer research, Female, Triple negative, medicine.drug, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f96b533c4da5dcf10c6f9b9bda90e4Test
http://hdl.handle.net/10261/135723Test

9

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2

المؤلفون: Luz Elena Núñez, Atanasio Pandiella, Juan Carlos Montero, Alberto Ocaña, Francisco Morís

المساهمون: Fundación Ramón Areces, Instituto de Salud Carlos III, European Commission, Fundación CRIS contra el Cáncer, Ministerio de Economía y Competitividad (España), Asociación Española Contra el Cáncer

المصدر: Oncotarget
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: Time Factors, medicine.medical_treatment, Apoptosis, Cell Cycle Proteins, Triple Negative Breast Neoplasms, ComputingMilieux_LEGALASPECTSOFCOMPUTING, Docetaxel, Pharmacology, Antineoplastic Combined Chemotherapy Protocols, Triple negative breast cancer, Phosphorylation, Triple-negative breast cancer, Mice, Inbred BALB C, Antibiotics, Antineoplastic, Nuclear Proteins, Plicamycin, Protein-Tyrosine Kinases, Cell cycle, Cyclin-Dependent Kinases, Tumor Burden, G2 Phase Cell Cycle Checkpoints, Oncology, Caspases, Female, Taxoids, Signal Transduction, Research Paper, medicine.drug, Mice, Nude, Inhibitory Concentration 50, Mithralogs, Breast cancer, Cell Line, Tumor, EC-8042, CDC2 Protein Kinase, medicine, Animals, Humans, Cell Proliferation, Chemotherapy, Dose-Response Relationship, Drug, Cell growth, business.industry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba31ee4da2ed465d54b7f8f39e62a50dTest
http://hdl.handle.net/10261/135835Test

10

Modulation of the activity of sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer

المؤلفون: Anastasia Malek, Marco Magistri, Francisco Morís, Sandra Jovic, Luz Elena Núñez, Giuseppina M. Carbone, Lara Brambilla, Carlo V. Catapano

المصدر: Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
PLoS ONE, Vol 7, Iss 4, p e35130 (2012)
PLoS ONE

مصطلحات موضوعية: Male, Mouse, Cancer Treatment, lcsh:Medicine, Pharmacology, Biochemistry, Metastasis, Mice, Prostate cancer, Prostate, Transcription (biology), Drug Discovery, Basic Cancer Research, Gene expression, Neoplasm Metastasis, lcsh:Science, Sp Transcription Factors, Mice, Inbred BALB C, Antibiotics, Antineoplastic, Multidisciplinary, Prostate Cancer, Plicamycin, Animal Models, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Oncology, Medicine, Research Article, Biotechnology, medicine.drug, Mice, Nude, Biology, Model Organisms, Cell Line, Tumor, DNA-binding proteins, medicine, Animals, Humans, Transcription factor, Cell Proliferation, Cell growth, lcsh:R, Prostatic Neoplasms, Proteins, Cancers and Neoplasms, Promoter, Chemotherapy and Drug Treatment, medicine.disease, Genitourinary Tract Tumors, Small Molecules, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0bd693fe8e9bc9086b2cee44cd7680Test
http://hdl.handle.net/10651/41514Test

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