نتائج البحث - "ALLOSTERIC MODULATION"

1

Structural Basis of Drug Recognition by Human Serum Albumin

المؤلفون: Alessandra Di Masi, Viviana Trezza, Loris Leboffe, Paolo Ascenzi, Fabio Polticelli

المساهمون: Leboffe, L., Di Masi, A., Polticelli, F., Trezza, V., Ascenzi, P., Leboffe, Lori, di Masi, Alessandra, Polticelli, Fabio, Trezza, Viviana, Ascenzi, Paolo

المصدر: Current Medicinal Chemistry. 27:4907-4931

مصطلحات موضوعية: Drug, Competitive modulation of drug binding, Drug carrier, media_common.quotation_subject, Allosteric regulation, Ligand, Serum Albumin, Human, Endogeny, Plasma protein binding, Ligands, 010402 general chemistry, 01 natural sciences, Biochemistry, 03 medical and health sciences, Pharmacokinetics, Drug Discovery, medicine, Humans, Binding site, 030304 developmental biology, media_common, Pharmacology, 0303 health sciences, Binding Sites, Chemistry, Organic Chemistry, Binding Site, Human serum albumin, 0104 chemical sciences, body regions, Drug recognition, Structural basi, competitive modulation of drug binding, embryonic structures, Allosteric modulation of drug binding, Molecular Medicine, Human, Protein Binding, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a0aea0285eabd57d39b5c5c07c1eb8Test
https://doi.org/10.2174/0929867326666190320105316Test

2

Allosteric modulation of G protein‐coupled receptors by amiloride and its derivatives. Perspectives for drug discovery?

المؤلفون: Arnault Massink, Tasia Amelia, Adriaan P. IJzerman, Alex Karamychev

المصدر: Medicinal Research Reviews
Medicinal Research Reviews, 40(2), 683-708

مصطلحات موضوعية: Allosteric regulation, Review Article, Receptors, G-Protein-Coupled, Amiloride, 03 medical and health sciences, 0302 clinical medicine, G protein-coupled receptors, Allosteric Regulation, G protein‐coupled receptors, Drug Discovery, medicine, N-hexamethylene)amiloride, 5‐(N,N‐hexamethylene)amiloride, Animals, Humans, Binding site, Receptor, Review Articles, 030304 developmental biology, G protein-coupled receptor, Pharmacology, 0303 health sciences, allosteric modulation, Drug discovery, Chemistry, Small molecule, 5-(N, 030220 oncology & carcinogenesis, Biophysics, Molecular Medicine, Sodium ion binding, hormones, hormone substitutes, and hormone antagonists, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ef56b63b0f374602c4e9c2510a6e1dTest
http://europepmc.org/articles/PMC7028016Test

3

It takes two—or more—to tango: Revisiting the role of dopamine transporter oligomerization

المؤلفون: Harald H. Sitte, Ulrik Gether

المصدر: The Journal of Biological Chemistry
Gether, U & Sitte, H H 2021, ' It takes two-or more-to tango : Revisiting the role of dopamine transporter oligomerization ', Journal of Biological Chemistry, vol. 296, 100629 . https://doi.org/10.1016/j.jbc.2021.100629Test

مصطلحات موضوعية: 0301 basic medicine, monoamine transporters, Allosteric regulation, AL, AIM-100-like compound, Endocytosis, Biochemistry, Reuptake, oligomerization, 03 medical and health sciences, Editors' Pick Highlight, Dopamine, DAT, dopamine transporter, medicine, Animals, Humans, endocytosis, Neurotransmitter sodium symporter, Molecular Biology, dopamine transporter, Dopamine transporter, Dopamine Plasma Membrane Transport Proteins, dimerization, allosteric modulation, 030102 biochemistry & molecular biology, biology, Chemistry, Transporter, Cell Biology, SERT, serotonin, Transmembrane protein, 030104 developmental biology, NET, norepinephrine, biology.protein, Biophysics, NSS, neurotransmitter:sodium symporter, Protein Multimerization, medicine.drug, TM, transmembrane

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dbc05ec5cee35576bc25e4aa4af8cdTest
http://europepmc.org/articles/PMC8100069Test

4

Allosteric Modulation of the CB1 Cannabinoid Receptor by Cannabidiol—A Molecular Modeling Study of the N-Terminal Domain and the Allosteric-Orthosteric Coupling

المؤلفون: Robert Preissner, Slawomir Filipek, Jakub Jakowiecki, Urszula Orzeł, Pawel Pasznik, Renata Abel

المصدر: Molecules, Vol 26, Iss 2456, p 2456 (2021)
Molecules
Volume 26
Issue 9

مصطلحات موضوعية: Models, Molecular, Allosteric modulator, Cannabinoid receptor, Magnetic Resonance Spectroscopy, THC, Molecular model, Stereochemistry, Allosteric regulation, Pharmaceutical Science, Organic chemistry, Plasma protein binding, Molecular Dynamics Simulation, Article, Protein Structure, Secondary, GPCRs, Analytical Chemistry, 03 medical and health sciences, 0302 clinical medicine, QD241-441, Allosteric Regulation, Receptor, Cannabinoid, CB1, Drug Discovery, medicine, interaction fingerprints, Animals, Cannabidiol, Humans, Physical and Theoretical Chemistry, 030304 developmental biology, G protein-coupled receptor, 0303 health sciences, allosteric modulation, Chemistry, REST2, cannabinoid receptor, CB1, digestive system diseases, molecular dynamics, Chemistry (miscellaneous), Docking (molecular), Molecular Medicine, CBD, 030217 neurology & neurosurgery, Allosteric Site, medicine.drug, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb09c905a0214e3a49ef4d73eed03e3bTest
https://www.mdpi.com/1420-3049/26/9/2456Test

5

Targeting the K(v)11.1 (hERG) channel with allosteric modulators

المؤلفون: Jacobus P. D. van Veldhoven, Constantijn J.E. van Gessel, Dorien Ward-van Oostwaard, Christine L. Mummery, Rongfang Liu, Giulia Campostrini, Milena Bellin, Adriaan P. IJzerman

المصدر: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 212:113033. Elsevier BV
European Journal of Medicinal Chemistry, 212. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a17cbc5b7a058d19fe58d9fbcf3538dTest
https://hdl.handle.net/1887/3221400Test

6

Menthol acts as a positive allosteric modulator on nematode levamisole sensitive nicotinic acetylcholine receptors

المؤلفون: Sasa M. Trailovic, Shivani Choudhary, Xiaoyu Zhang, Djordje S. Marjianović, Joel R. Coats, Alan P. Robertson, Richard J. Martin, Colin R. Wong, Melanie Abongwa

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 9, Iss, Pp 44-53 (2019)
International Journal for Parasitology-Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance

مصطلحات موضوعية: 0301 basic medicine, Allosteric modulator, 030231 tropical medicine, Cholinergic Agents, Receptors, Nicotinic, nAChR, Pharmacology, Article, lcsh:Infectious and parasitic diseases, Nicotine, Xenopus laevis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Allosteric Regulation, medicine, Animals, lcsh:RC109-216, Pharmacology (medical), Receptor, Allosteric modulation, Ascaris suum, Nematode, Acetylcholine receptor, Anthelmintics, Monoterpenoid, 3. Good health, Oesophagostomum, Menthol, 030104 developmental biology, Infectious Diseases, Nicotinic agonist, Levamisole, chemistry, Monoterpenes, Cholinergic, Female, Parasitology, Acetylcholine, medicine.drug