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1
المؤلفون: Sujata Rao, Rakesh Verma, Todd M. Bauer, Aung Naing, J. Leveque, Raid Aljumaily, Zev A. Wainberg, Johanna C. Bendell, J. Randolph Hecht, Gerald Steven Falchook, Martin Oft, Annie Hung, Karen A. Autio, Shubham Pant, Jeffrey R. Infante, Navneet Ratti, Deborah J. Wong, Manish R. Patel, Kyriakos P. Papadopoulos, Peter VanVlasselaer, Milind Javle
المصدر: Investigational new drugs, vol 39, iss 1
Invest New Drugsمصطلحات موضوعية: 0301 basic medicine, Oncology, Organoplatinum Compounds, Metastatic pancreatic adenocarcinoma, Leucovorin, Phases of clinical research, Kaplan-Meier Estimate, Polyethylene Glycols, 0302 clinical medicine, FOLFOX, Antineoplastic Combined Chemotherapy Protocols, Pharmacology (medical), 6.2 Cellular and gene therapies, Cancer, education.field_of_study, Pharmacology and Pharmaceutical Sciences, Middle Aged, Progression-Free Survival, Interleukin-10, Tolerability, Pancreatic Ductal, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, IL-10, Fluorouracil, Pegilodecakin, Drug, Carcinoma, Pancreatic Ductal, medicine.drug, Adult, medicine.medical_specialty, Clinical Trials and Supportive Activities, Population, Phase 1, Article, Dose-Response Relationship, Pancreatic Cancer, 03 medical and health sciences, Rare Diseases, Clinical Research, Internal medicine, medicine, Humans, Oncology & Carcinogenesis, Pegylated IL-10, Adverse effect, education, Response Evaluation Criteria in Solid Tumors, Neoplasm Staging, Aged, Pharmacology, Dose-Response Relationship, Drug, business.industry, Carcinoma, Evaluation of treatments and therapeutic interventions, digestive system diseases, Oxaliplatin, Pancreatic Neoplasms, Regimen, 030104 developmental biology, Tumor progression, Digestive Diseases, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69d0ddd9f3551a8ca0a4d0daab7d846Test
https://doi.org/10.1007/s10637-020-01000-6Test -
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المؤلفون: Ruth Plummer, Rachel E. Sanborn, Fiona C Thistlethwaite, Omid Hamid, Daniel C. Cho, Lawrence Lu, Valentina Boni, Johanna C. Bendell, Mark Stroh, Elisabeth G.E. de Vries, Karen A. Autio, Patrick A. Ott, Javier Garcia-Corbacho
المساهمون: Guided Treatment in Optimal Selected Cancer Patients (GUTS)
المصدر: Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Journal for immunotherapy of cancer, 9(7):002446. BMCمصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Gastroenterology, B7-H1 Antigen, 0302 clinical medicine, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Immunology and Allergy, Prodrugs, Immune Checkpoint Inhibitors, RC254-282, Clinical/Translational Cancer Immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Antibodies, Monoclonal, Middle Aged, Oncology, Tolerability, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, Toxicity, Molecular Medicine, Female, immunotherapy, medicine.drug, Adult, CTLA-4 antigen, medicine.medical_specialty, Combination therapy, Immunology, therapies, Ipilimumab, investigational, 03 medical and health sciences, Internal medicine, medicine, Humans, Testicular cancer, Pneumonitis, Aged, Pharmacology, Dose-Response Relationship, Drug, business.industry, medicine.disease, 030104 developmental biology, NIVOLUMAB PLUS IPILIMUMAB, PD-L1 inhibitor, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f59b5f6c6c998d04c0063e8f4efa570Test
https://pubmed.ncbi.nlm.nih.gov/34301808Test -
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المؤلفون: Herbert Hurwitz, Vaibhav Sahai, Chris Verslype, Jason Clark, Johanna C. Bendell, Ashwin Reddy Sama, Eric Van Cutsem, Manuel Hidalgo, Edward W Greeno, Eileen M. O'Reilly, Chung Pin Li, Kenneth H. Yu, Christopher James Walker, Fitzroy Dawkins, Teresa Macarulla, Marcelo Garrido Salvo
المصدر: Investigational New Drugs. 36:683-695
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Ruxolitinib, Placebo, Disease-Free Survival, Article, Capecitabine, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Pancreatic cancer, Antineoplastic Combined Chemotherapy Protocols, Nitriles, medicine, Clinical endpoint, Humans, Pharmacology (medical), Aged, Aged, 80 and over, Pharmacology, business.industry, Hazard ratio, Janus Kinase 1, Janus Kinase 2, Middle Aged, medicine.disease, Chemotherapy regimen, Pancreatic Neoplasms, Clinical trial, Pyrimidines, 030104 developmental biology, 030220 oncology & carcinogenesis, Disease Progression, Pyrazoles, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4efb9dd95fab56ab09c97a08030248fTest
https://doi.org/10.1007/s10637-018-0580-2Test -
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المؤلفون: Erika Hamilton, Hani Gabra, Kathleen M. Moore, Jennifer R. Diamond, Mark Poole, D. Ross Camidge, Martin D. Forster, Michael S. Gordon, David M. Waterhouse, Barbara A. Goff, Carolyn D. Britten, Johanna C. Bendell
المصدر: Invest New Drugs
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, Mitochondrial inhibitor, Cell, Uterine Cervical Neoplasms, Neutropenia, Article, Drug Administration Schedule, 03 medical and health sciences, 0302 clinical medicine, Stable Disease, Pharmacokinetics, Ovarian cancer, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, ME-344, Pharmacology (medical), Oncology & Carcinogenesis, Aged, Ovarian Neoplasms, Pharmacology, Lung, Dose-Response Relationship, Drug, Small cell lung cancer, business.industry, Middle Aged, medicine.disease, Isoflavones, Mitochondria, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Toxicity, Female, 1115 Pharmacology And Pharmaceutical Sciences, Topotecan, Neoplasm Recurrence, Local, Topoisomerase I Inhibitors, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14dee4e7e022a14638395d5059e46ddfTest
https://doi.org/10.1007/s10637-017-0444-1Test -
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المؤلفون: Sunil Sharma, Emin Avsar, Kati Maharry, Jan H.M. Schellens, Anna Spreafico, Rona Yaeger, Martin Schuler, Jason E. Faris, Takayuki Yoshino, Arkendu Chatterjee, Savina Jaeger, Ferry A.L.M. Eskens, Johanna C. Bendell, Tim Demuth, Josep Tabernero, Martijn P. Lolkema, Zev A. Wainberg, Yasuhide Yamada, Jean Pierre Delord, Robin M.J.M. van Geel, Eugene Tan, Elena Elez, Heinz-Josef Lenz
المساهمون: MUMC+: DA KFT Medische Staf (9), RS: FHML non-thematic output, Medical Oncology
المصدر: Cancer Discovery, 7(6), 610-619. American Association for Cancer Research Inc.
Cancer discovery, vol 7, iss 6
Cancer Discovery, 7(6), 610. American Association for Cancer Research Inc.مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Colorectal cancer, Medizin, Cetuximab, Raf Kinase Inhibitor, Pharmacology, 0302 clinical medicine, Encorafenib, Antineoplastic Combined Chemotherapy Protocols, 80 and over, Phosphoinositide-3 Kinase Inhibitors, Cancer, Aged, 80 and over, Sulfonamides, COLON-CANCER, Middle Aged, Clinical Trial, Colo-Rectal Cancer, 3. Good health, Multicenter Study, Tolerability, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Maximum Tolerated Dose, EGFR, Oncology and Carcinogenesis, BIOMARKERS, INHIBITION, Antineoplastic Agents, Disease-Free Survival, Clinical Trial, Phase I, 03 medical and health sciences, Phase I, SDG 3 - Good Health and Well-being, Clinical Research, Internal medicine, MAPK PATHWAY, medicine, Journal Article, KRAS, Humans, WILD-TYPE, neoplasms, Protein Kinase Inhibitors, Aged, business.industry, Evaluation of treatments and therapeutic interventions, RAF, medicine.disease, digestive system diseases, FLUOROURACIL, Clinical trial, Thiazoles, 030104 developmental biology, Concomitant, Mutation, GENE COPY NUMBER, Carbamates, Phosphatidylinositol 3-Kinase, Digestive Diseases, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a74efca771fba8318569827a37a712fTest
https://hdl.handle.net/1765/108310Test -
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المؤلفون: Michael S. Gordon, Shirin Arastu-Kapur, Hansen L. Wong, Johanna C. Bendell, Jeffrey R. Infante, Howard A. Burris, Anthony W. Tolcher, David S. Mendelson, Heidi H. Gillenwater, Kyriakos P. Papadopoulos
المصدر: Investigational New Drugs. 34:216-224
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Maximum Tolerated Dose, Nausea, Administration, Oral, Antineoplastic Agents, Pharmacology, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Neoplasms, Internal medicine, medicine, Humans, Pharmacology (medical), Adverse effect, Aged, Neoplasm Staging, Aged, 80 and over, Dose-Response Relationship, Drug, business.industry, Middle Aged, medicine.disease, Carfilzomib, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Pharmacodynamics, Vomiting, Proteasome inhibitor, Female, medicine.symptom, business, Oligopeptides, Proteasome Inhibitors, Hypophosphatemia, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b434cde377daa673bea93ab1e8657bTest
https://doi.org/10.1007/s10637-016-0327-xTest -
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المؤلفون: Patrick Murphy, Lowell L. Hart, Adil Moyhuddin, Jeffrey Patton, Dana S. Thompson, Suzanne F. Jones, Chris Earwood, Jeffrey R. Infante, Shubham Pant, Johanna C. Bendell, William Charles Penley, Cassie M. Lane
المصدر: Cancer Investigation. 33:477-482
مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Pharmacology, Gastroenterology, Capecitabine, Stable Disease, Neoplasms, Partial response, Internal medicine, medicine, Humans, HSP90 Heat-Shock Proteins, Hsp90 Inhibitor AUY922, Aged, business.industry, Isoxazoles, Resorcinols, General Medicine, Middle Aged, Phase i study, Diarrhea, Oncology, Fluorouracil, Maximum tolerated dose, Female, medicine.symptom, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522d00ebf1128ee0f4191dcdeae22ebdTest
https://doi.org/10.3109/07357907.2015.1069834Test -
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المؤلفون: YanYan Zhou, Alicia Allred, Johanna C. Bendell, Howard A. Burris, Michael S. Gordon, Suzanne F. Jones, Donna S. Cox, Keith W. Orford, Jeffrey R. Infante
المصدر: Clinical Pharmacology in Drug Development. 4:287-294
مصطلحات موضوعية: Trametinib, business.industry, MEK inhibitor, Cmax, Pharmaceutical Science, Dabrafenib, Pharmacology, Crossover study, Bioavailability, Pharmacokinetics, Medicine, Pharmacology (medical), business, Adverse effect, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e87769620e990c51bc8f964319efb7e9Test
https://doi.org/10.1002/cpdd.152Test -
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المؤلفون: J. H. Barton, David R. Spigel, Chris Earwood, Johanna C. Bendell, Lowell L. Hart, Cassie M. Lane, Howard A. Burris, Suzanne F. Jones, Jeffrey R. Infante
المصدر: Investigational New Drugs. 33:187-193
مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Linsitinib, Maximum Tolerated Dose, Colorectal cancer, Neutropenia, Receptor, IGF Type 1, chemistry.chemical_compound, Refractory, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Mucositis, Humans, Medicine, Pharmacology (medical), Everolimus, Adverse effect, Protein Kinase Inhibitors, Aged, Sirolimus, Pharmacology, Performance status, business.industry, Imidazoles, Middle Aged, medicine.disease, chemistry, Pyrazines, Female, Colorectal Neoplasms, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3606b88aa816d856b6c6a4d17473f3eTest
https://doi.org/10.1007/s10637-014-0177-3Test -
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المؤلفون: Kelly Levinson, J. R. Infante, Suzanne F. Jones, Afshin Dowlati, Michael P. Kane, H. A. Burris, Johanna C. Bendell, Mark N. Stein, Antoinette R. Tan, A B Suttle
المصدر: British Journal of Cancer
مصطلحات موضوعية: Adult, Male, Cancer Research, Indazoles, Lung Neoplasms, Maximum Tolerated Dose, Paclitaxel, Neutropenia, Pharmacology, Lapatinib, Drug Administration Schedule, Pazopanib, EGFR and HER2 tyrosine kinase inhibitor, chemistry.chemical_compound, Pharmacokinetics, Carcinoma, Non-Small-Cell Lung, Antineoplastic Combined Chemotherapy Protocols, pazopanib, Humans, Medicine, lapatinib, skin and connective tissue diseases, Aged, Sulfonamides, business.industry, Area under the curve, Middle Aged, Salivary Gland Neoplasms, medicine.disease, vascular endothelial growth factor receptor tyrosine kinase inhibitor, Regimen, Biliary Tract Neoplasms, Pyrimidines, Treatment Outcome, Oncology, chemistry, Tolerability, Clinical Study, Quinazolines, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c862256b7196b7ba8fe14049ad312dfTest
https://doi.org/10.1038/bjc.2014.233Test