نتائج البحث - "Orian S. Shirihai"

1

IRGM1 links mitochondrial quality control to autoimmunity

المؤلفون: Michael B. Fessler, Julie M. Meacham, Mark W. Grinstaff, Kyathanahalli S. Janardhan, Gregory A. Taylor, Orian S. Shirihai, Jennifer H. Madenspacher, Mei Yan, Wan Chi Lin, Prashant Rai, Jennifer Martinez, Jialiu Zeng, Quan Zhen Li, Peer W. F. Karmaus

المصدر: Nat Immunol

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc485527207d70e1e2427b9ebee176ceTest
https://pubmed.ncbi.nlm.nih.gov/33547457Test

2

Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

المؤلفون: Ting Chen, Peter S. Hammerman, Julia M. Nagle, Nicholas J. Dyson, Brandon Nicolay, Ahlima Roumane, Myriam Boukhali, D. Neil Hayes, Hongcang Gu, Alexander Meissner, Rahul Karnik, Kwok-Kin Wong, Orian S. Shirihai, Yvonne Y. Li, Michele C. Hayward, Marc Liesa, Wilhelm Haas, Nabeel Bardeesy, Filippos Kottakis

المصدر: Nature

مصطلحات موضوعية: Serine, congenital, hereditary, and neonatal diseases and abnormalities, Multidisciplinary, DNA methylation, medicine, Metabolism, Computational biology, Biology, skin and connective tissue diseases, Carcinogenesis, medicine.disease_cause

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c988ed0bae5252eed8af6f24d1e8832Test
https://doi.org/10.1038/s41586-019-1696-zTest

3

Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells

المصدر: Stem Cell Reports, Vol 4, Iss 5, Pp 873-885 (2015)
Stem Cell Reports

مصطلحات موضوعية: Epigenomics, Cellular differentiation, Induced Pluripotent Stem Cells, Enzyme-Linked Immunosorbent Assay, Biology, medicine.disease_cause, Biochemistry, Article, Transcriptome, Directed differentiation, Autophagy, Genetics, medicine, Humans, Induced pluripotent stem cell, lcsh:QH301-705.5, Alleles, Cells, Cultured, Oligonucleotide Array Sequence Analysis, lcsh:R5-920, Mutation, Alpha 1-antitrypsin deficiency, Liver Diseases, Cell Differentiation, Cell Biology, DNA Methylation, medicine.disease, Molecular biology, 3. Good health, Carbamazepine, lcsh:Biology (General), alpha 1-Antitrypsin, DNA methylation, Hepatocytes, Cancer research, Hepatic stellate cell, lcsh:Medicine (General), Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8125970c350943fbe45427c1fc4028e2Test
https://doi.org/10.1016/j.stemcr.2015.02.021Test

4

A bioenergetic profile of non-transformed fibroblasts uncovers a link between death-resistance and enhanced spare respiratory capacity

المؤلفون: Jakob D. Wikstrom, Orian S. Shirihai, Kristen P. Nickens, Steven R. Patierno, Susan Ceryak

المصدر: Mitochondrion. 13:662-667

مصطلحات موضوعية: Programmed cell death, Cell Death, Bioenergetics, Cell Biology, Fibroblasts, Biology, Mitochondrion, medicine.disease_cause, Article, Cell Line, Cell biology, Electron Transport, Apoptosis, Cell culture, Cancer cell, medicine, Humans, Molecular Medicine, Energy Metabolism, Carcinogenesis, Clonogenic assay, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826492ecb40dfde07aebcf5645045abdTest
https://doi.org/10.1016/j.mito.2013.09.005Test

5

ABCB10 deletion in cardiomyocytes leads to mitochondrial dysfunction and early death

المؤلفون: Orian S. Shirihai, Marc Liesa, Aaron L. Sverdlov, Deborah A. Siwik, Dominique Croteau, Aly Elezaby, Jordan M. Chambers, Wilson S. Colucci, Ivan Luptak, David R. Pimentel

المصدر: Free Radical Biology and Medicine. 128:S22

مصطلحات موضوعية: chemistry.chemical_classification, medicine.medical_specialty, Reactive oxygen species, Antioxidant, medicine.medical_treatment, Ischemia, Wild type, Mitochondrion, medicine.disease_cause, medicine.disease, Biochemistry, Endocrinology, chemistry, Physiology (medical), Internal medicine, Knockout mouse, medicine, MYH6, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::035c660a93df2badda1b06aad9765d31Test
https://doi.org/10.1016/j.freeradbiomed.2018.10.007Test

6

Salen Mn Complexes are Superoxide Dismutase/Catalase Mimetics that Protect the Mitochondria

المؤلفون: Marc Liesa, Simon Melov, Philip J. Tofilon, Orian S. Shirihai, Susan R. Doctrow

المصدر: Current Inorganic Chemistrye. 2:325-334

مصطلحات موضوعية: biology, Chemistry, Superoxide, General Engineering, Respiratory chain, Oxidative phosphorylation, Mitochondrion, medicine.disease_cause, medicine.disease, Cell biology, Superoxide dismutase, chemistry.chemical_compound, Catalase, medicine, biology.protein, General Earth and Planetary Sciences, Reperfusion injury, Oxidative stress, General Environmental Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f01262ee3d636cf4b5292cc146640129Test
https://doi.org/10.2174/1877944111202030325Test

7

Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease

المؤلفون: Deborah A. Siwik, Markus Bachschmid, Aly Elezaby, Orian S. Shirihai, Timothy D. Calamaras, Aaron L. Sverdlov, Ivan Luptak, Fuzhong Qin, David R. Pimentel, Wilson S. Colucci, Jessica B. Behring, Marc Liesa, Richard A. Cohen, Edward J. Miller

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial ROS, obesity, Mitochondrial Diseases, Mitochondrion, medicine.disease_cause, Mitochondria, Heart, Ventricular Function, Left, chemistry.chemical_compound, Ventricular Dysfunction, Left, Adenosine Triphosphate, Dietary Sucrose, Medicine, oxidative stress, Original Research, 2. Zero hunger, chemistry.chemical_classification, Metabolic Syndrome, biology, ATP synthase, oxidative protein modifications, Electron Transport Complex II, metabolic heart disease, Catalase, mitochondria, Hypertrophy, Left Ventricular, Cardiology and Cardiovascular Medicine, Oxidation-Reduction, medicine.medical_specialty, Mice, Transgenic, Oxidative phosphorylation, Diet, High-Fat, 03 medical and health sciences, Internal medicine, Animals, Heart Failure, Reactive oxygen species, Electron Transport Complex I, business.industry, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, chemistry, Animal Models of Human Disease, Mutation, biology.protein, Contractile function, business, Oxidant Stress, Energy Metabolism, Reactive Oxygen Species, Adenosine triphosphate, Protein Processing, Post-Translational, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b479bd062916844c4294122158d5a1d4Test
http://europepmc.org/articles/PMC4859372Test

8

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

المؤلفون: Julia M. Nagle, Marc Liesa, Ahlima Roumane, Brandon Nicolay, Peter S. Hammerman, Myriam Boukhali, Michele C. Hayward, Orian S. Shirihai, Nabeel Bardeesy, Wilhelm Haas, Nicholas J. Dyson, Yvonne Y. Li, Kwok-Kin Wong, Ting Chen, Rahul Karnik, Filippos Kottakis, Hongcang Gu, Alexander Meissner, D. Neil Hayes

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, S-Adenosylmethionine, Methyltransferase, Retroelements, Cell Culture Techniques, Glycine, Biology, AMP-Activated Protein Kinases, Protein Serine-Threonine Kinases, medicine.disease_cause, Article, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, chemistry.chemical_compound, Mice, AMP-Activated Protein Kinase Kinases, Cell Line, Tumor, medicine, Serine, Gene silencing, Animals, Humans, Genes, Tumor Suppressor, Epigenetics, DNA (Cytosine-5-)-Methyltransferases, Gene Silencing, Enzyme Inhibitors, Gene, Transaminases, Multidisciplinary, Kinase, TOR Serine-Threonine Kinases, Pancreatic Ducts, Epithelial Cells, DNA Methylation, Chromatin, Cell biology, 030104 developmental biology, Cell Transformation, Neoplastic, chemistry, Biochemistry, DNA methylation, Carcinogenesis, Glycolysis, DNA

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bae729bcc73d50e1436d2a04b403542Test

9

Mitochondrial Transporter ATP Binding Cassette Mitochondrial Erythroid Is a Novel Gene Required for Cardiac Recovery After Ischemia/Reperfusion

المؤلفون: Deborah A. Siwik, Neil B. Ruderman, David R. Pimentel, Wilson S. Colucci, X. Julia Xu, Ergun Sahin, Fuzhong Qin, Karl Huffman, Ivan Luptak, Marc Liesa, Lauren Richey, Zhengkun Zhu, Brigham B. Hyde, Susan R. Doctrow, Orian S. Shirihai

المصدر: Circulation. 124:806-813

مصطلحات موضوعية: Cardiac function curve, Ischemia, ATP-binding cassette transporter, Transporter, Oxidative phosphorylation, Mitochondrion, Biology, medicine.disease, medicine.disease_cause, Molecular biology, Physiology (medical), Ventricular pressure, medicine, Cardiology and Cardiovascular Medicine, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9faa928433c1457ef7812d55fcaf84caTest
https://doi.org/10.1161/circulationaha.110.003418Test

10

A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity

المؤلفون: Orian S. Shirihai, Shuxi Qiao, Xiufeng Song, Douangsone D. Vadysirisack, Richard T. Lee, John C. Reed, Marc Liesa, Zhifen Yang, Leif W. Ellisen, Devika Salunke, Michael Dennis, Shu-ichi Matsuzawa, Zachary M. Nash, Jun Yoshioka

المصدر: Nature Communications

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0dd4fbb43d3d10e38dc11321758e5cTest
https://pubmed.ncbi.nlm.nih.gov/25916556Test

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