المؤلفون: Catalina Anghel, Dennis S. Deng, Richard B. Richardson

المصدر: Aging (Albany NY)

مصطلحات موضوعية: Adult, Male, Oncology, Senescence, Aging, medicine.medical_specialty, cancer incidence, Adolescent, driver mutations, Carcinogenesis, Cancer Model, Biology, Gene mutation, cancer model, medicine.disease_cause, Young Adult, Neoplasms, Internal medicine, SEER program, medicine, Humans, Stage (cooking), Child, Carcinogen, Aged, Aged, 80 and over, Incidence, Tumor Suppressor Proteins, Incidence (epidemiology), Age Factors, Infant, Newborn, Infant, Cancer, Cell Biology, Middle Aged, medicine.disease, Child, Preschool, Female, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe5d76d58352eca5e863127812850f2Test
https://doi.org/10.18632/aging.203651Test

المؤلفون: Manoj Kumar Panigrahi, Smreti Vasudevan, Ullas Batra, Sanjeev Sharma, Anurag Mehta, Moushumi Suryavanshi, Mumtaz Saifi

المصدر: Applied Cancer Research, Vol 40, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, medicine.disease_cause, lcsh:RC254-282, DNA sequencing, Tyrosine-kinase inhibitor, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Compound mutations, Lung cancer, Gene, High-throughput sequencing, business.industry, Driver mutations, General Medicine, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Clinical trial, 030104 developmental biology, Fusion transcript, 030220 oncology & carcinogenesis, KRAS, business, Single-gene assay

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8c5360a27951783b5a285642e3f492Test
http://link.springer.com/article/10.1186/s41241-020-00089-8Test

المؤلفون: Jarom Heijmans, Wouter L. Smit

المساهمون: Graduate School, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, General Internal Medicine, Clinical Haematology

المصدر: Mol Cell Oncol
Molecular & cellular oncology, 8(4):1879614. Taylor and Francis Ltd.

مصطلحات موضوعية: Cancer Research, Messenger RNA, driver mutations, protein synthesis, Colorectal cancer, Translation (biology), Biology, medicine.disease_cause, medicine.disease, Cell biology, Transformation (genetics), Organoid, medicine, Protein biosynthesis, mTOR signaling, Author’s Views, Molecular Medicine, KRAS, Enhancer, neoplasms, global translation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8194db6dbc28c579cbb0459b38a72ff4Test
https://pubmed.ncbi.nlm.nih.gov/34616863Test

المؤلفون: Yael P. Mosse, Courtney M. Smith, Krishna Suresh, Ravi Radhakrishnan, Abigail A Lemmon, Keshav Patil, Jin H. Park, Mark A. Lemmon, Earl Joseph Jordan

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, alpha-Helical, driver mutations, Disease, Computational biology, Biology, Molecular Dynamics Simulation, medicine.disease_cause, kinase activation, Machine Learning, 03 medical and health sciences, 0302 clinical medicine, medicine, Anaplastic lymphoma kinase, Humans, Anaplastic Lymphoma Kinase, chemistry.chemical_classification, Mutation, Multidisciplinary, Kinase, Cancer, Biological Sciences, medicine.disease, molecular dynamics, Amino acid, focus formation assay, Enzyme Activation, Biophysics and Computational Biology, 030104 developmental biology, chemistry, Protein kinase domain, 030220 oncology & carcinogenesis, Target protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9199b12102cdd0e542ec239a708e35afTest
http://europepmc.org/articles/PMC7958353Test

المؤلفون: Eugene V. Koonin, Noam Auslander, Yuri I. Wolf

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: driver mutations, In silico, passenger mutations, Computational biology, Biology, medicine.disease_cause, Evolution, Molecular, Neoplasms, Databases, Genetic, Genetics, medicine, Humans, Computer Simulation, Gene, Sequence (medicine), Mutation, Multidisciplinary, Models, Genetic, Artificial neural network, Cancer, Biological Sciences, neural networks, medicine.disease, cancer progression, machine learning, Recurrent neural network, PNAS Plus, Tumor progression, Neural Networks, Computer, human activities, Algorithms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e695ca23c7551821fa393e7261e29048Test
https://doi.org/10.1073/pnas.1901695116Test

المؤلفون: Claudia N. Spaan, Jarom Heijmans, Jan Koster, Ruben J. de Boer, Alyson W. MacInnes, Jacqueline Ludovicus Maria Vermeulen, Wouter L. Smit, Gijs R. van den Brink, Tânia Martins Garcia, Jan Paul Medema, Marco Lezzerini, Vanesa Muncan, Prashanthi Ramesh, Bartolomeus J. Meijer

المساهمون: Graduate School, Tytgat Institute for Liver and Intestinal Research, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Gastroenterology and Hepatology, CCA - Cancer biology and immunology, Laboratory for General Clinical Chemistry, Oncogenomics, Center of Experimental and Molecular Medicine, Radiotherapy, General Internal Medicine

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 117(41), 25560-25570. National Academy of Sciences
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Adenoma, Cell division, Mice, Transgenic, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, medicine.disease_cause, Tissue Culture Techniques, Mice, medicine, Animals, Humans, Gene knockdown, Multidisciplinary, Carcinoma, EIF4E, Driver mutations, Translation (biology), Biological Sciences, Colorectal cancer, Cell biology, Intestines, Organoids, HEK293 Cells, Protein Biosynthesis, Mutation, Cancer cell, KRAS, Global translation, Colorectal Neoplasms, Protein synthesis, Reprogramming, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc285b42dbd5905f7bee76ae706c536Test
https://pure.amc.nl/en/publicationsTest/driver-mutations-of-the-adenomacarcinoma-sequence-govern-the-intestinal-epithelial-global-translational-capacity(b9887a9c-b0c1-49aa-bfe1-d01c5e5c2282).html

المؤلفون: Clare Fiala, Eleftherios P. Diamandis

المصدر: BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: 0301 basic medicine, Adult, DNA Mutational Analysis, Normal tissue, lcsh:Medicine, Context (language use), Disease, Review, medicine.disease_cause, Normal tissues, 03 medical and health sciences, Young Adult, 0302 clinical medicine, medicine, Humans, Gene, Aged, Mutation, Circulating tumor DNA, business.industry, lcsh:R, Driver mutations, Cancer, General Medicine, Middle Aged, medicine.disease, 030104 developmental biology, The Hallmarks of Cancer, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, business, Mutations, Passenger mutations

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e5e26cfddf582179c94bbbc1336f44Test
http://europepmc.org/articles/PMC7594459Test

المؤلفون: Irene Vanni, Enrica Teresa Tanda, Bruna Dalmasso, Lorenza Pastorino, Virginia Andreotti, William Bruno, Andrea Boutros, Francesco Spagnolo, Paola Ghiorzo

المصدر: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 7 (2020)

مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Mutation rate, driver mutations, medicine.medical_treatment, Disease, Review, Biology, medicine.disease_cause, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, medicine, melanoma, Molecular Biosciences, Gene, Molecular Biology, lcsh:QH301-705.5, non-BRAF mutation, Mutation, Genetic heterogeneity, Melanoma, medicine.disease, targeted therapy, 030104 developmental biology, lcsh:Biology (General), 030220 oncology & carcinogenesis, Cancer research, genetic, heterogeneity, WES, WGS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963d6500283ca19c51304fc876c8998cTest
http://europepmc.org/articles/PMC7396525Test

المؤلفون: Swapnil Rajurkar, TingTing Tan, Isa Mambetsariev, Ravi Salgia, Benjamin I. Leach, Prakash Kulkarni, Rebecca Pharaon

المصدر: Journal of Clinical Medicine, Vol 9, Iss 1870, p 1870 (2020)
Journal of Clinical Medicine

مصطلحات موضوعية: Oncology, medicine.medical_specialty, driver mutations, lcsh:Medicine, Genomics, Disease, Review, team medicine, medicine.disease_cause, 03 medical and health sciences, 0302 clinical medicine, Electronic health record, Internal medicine, Medicine, Personalized therapy, Lung cancer, non-small cell lung cancer, 030304 developmental biology, 0303 health sciences, testing rates, receptor tyrosine kinases, business.industry, lcsh:R, General Medicine, medicine.disease, 030220 oncology & carcinogenesis, Community practice, Non small cell, business, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c361ca52fa1d5f6e396ace21b80dd8Test
https://www.mdpi.com/2077-0383/9/6/1870Test

المؤلفون: Hans Clevers, Ivana Bozic, Chay Paterson

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Paterson, C, Clevers, H & Bozic, I 2020, ' Mathematical model of colorectal cancer initiation ', Proceedings of the National Academy of Sciences, vol. 117, no. 34, pp. 20681-20688 . https://doi.org/10.1073/pnas.2003771117Test
Proceedings of the National Academy of Sciences of the United States of America, 117(34), 20681-20688. National Academy of Sciences
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Mutation rate, Genes, APC, Carcinogenesis, Colorectal cancer, medicine.disease_cause, law.invention, Cancer evolution, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins p21(ras)/genetics, Genes, APC/physiology, Immune system, Theoretical, Mutation Rate, law, Models, Genotype, Medicine, Humans, p53/genetics, ras, Mutation, Multidisciplinary, Oncogene, business.industry, APC/physiology, Driver mutations, Cancer, Colonic Neoplasms/genetics, Oncogenes, Biological Sciences, Models, Theoretical, Genes, p53, medicine.disease, Colorectal Neoplasms/genetics, Genes, p53/genetics, Genes, ras, Stochastic model, Genes, Colonic Neoplasms, Cancer research, Disease Progression, Suppressor, Tumor Suppressor Protein p53/genetics, KRAS, Carcinogenesis/genetics, Tumor Suppressor Protein p53, Colorectal Neoplasms, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0be1b6f7a2a90b22b288ed47a748750Test