المؤلفون: Michael H. Criqui, Kate Kosmac, Charlotte A. Peterson, Lingyu Li, A. Zenobia Moore, Lu Tian, C. Leeuwenburgh, Luigi Ferrucci, Melina R. Kibbe, Jack M. Guralnik, Tamar S. Polonsky, Robert L. Sufit, Mary M. McDermott, Marta Gonzalez-Freire

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association, vol 9, iss 7

مصطلحات موضوعية: Male, Translational Studies, humanos, ADN, Walking, Cardiorespiratory Medicine and Haematology, 030204 cardiovascular system & hematology, Severity of Illness Index, 0302 clinical medicine, Microheteroplasmy, Ischemia, Clinical Studies, heteroplasmy, D-loop, D‐loop, mediana edad, Original Research, Randomized Controlled Trials as Topic, anciano, 0303 health sciences, mtDNA, ensayos clínicos controlados aleatorizados como asunto, Middle Aged, Heteroplasmy, Mitochondria, medicine.anatomical_structure, Female, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Mitochondrial DNA, mtDNA copy number, estudios de casos y controles, arteriopatía periférica, peripheral artery disease, Pathophysiology, DNA, Mitochondrial, pierna, Peripheral Arterial Disease, 03 medical and health sciences, Gastrocnemius muscle, Internal medicine, Diabetes mellitus, Genetics, medicine, Humans, índice de gravedad de la enfermedad, Mobility Limitation, Muscle, Skeletal, caminata, Aged, 030304 developmental biology, mitocondrias, Leg, business.industry, Skeletal muscle, DNA, medicine.disease, Mitochondria, Muscle, body regions, ankle brachial index, Cross-Sectional Studies, Endocrinology, Case-Control Studies, limitación de la movilidad, isquemia, Oxidant Stress, business, estudios transversales

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5398ad34c76dd1bae32c8b563856756Test
https://doi.org/10.1161/jaha.119.015197Test

المؤلفون: Jennifer A. Smith, Andrea A. Baccarelli, Jordana T. Bell, James B. Meigs, James S. Pankow, Jun Liu, Ayse Demirkan, Marjolein J. Peters, Jerome I. Rotter, Elias Salfati, Bertha Hidalgo, Audrey Y. Chu, André G. Uitterlinden, Luigi Ferrucci, Pooja R. Mandaviya, Nona Sotoodehnia, Eric A. Whitsel, Liesbeth Duijts, Marie-France Hivert, Elena Carnero-Montoro, Eric J.G. Sijbrands, Ann Zenobia Moore, Janine F. Felix, Jenny van Dongen, Najaf Amin, Tim D. Spector, Oscar H. Franco, Harald Grallert, Tiphaine Martin, Ivana Nedeljkovic, Josée Dupuis, Aaron Isaacs, Themistocles L. Assimes, Pei-Chien Tsai, Cornelia M. van Duijn, Lifang Hou, Daniel Levy, Ko Willems van Dijk, Rahul Gondalia, Samantha Lent, Abbas Dehghan, Rozenn N. Lemaitre, Jan Bressler, Christian Herder, Min A. Jhun, Symen Ligthart, Dorret I. Boomsma, Gonneke Willemsen, Toshiko Tanaka, Rick Jansen, Joyce B. J. van Meurs, Shih-Jen Hwang, Vincent W. V. Jaddoe, Donna K. Arnett, Eco J. C. de Geus, Henning Tiemeier, Stefania Bandinelli

المساهمون: Pediatric surgery, Epidemiology and Data Science, Biological Psychology, APH - Mental Health, APH - Personalized Medicine, APH - Methodology, Epidemiology, Internal Medicine, Pediatrics, Erasmus MC other, Child and Adolescent Psychiatry / Psychology, RS: CARIM - R1 - Thrombosis and haemostasis, RS: FHML MaCSBio, Biochemie, RS: Carim - B01 Blood proteins & engineering

المصدر: Liu, Jun; Carnero-Montoro, Elena; van Dongen, Jenny; Lent, Samantha; Nedeljkovic, Ivana; Ligthart, Symen; Tsai, Pei-Chien; Martin, Tiphaine C; Mandaviya, Pooja R; Jansen, Rick; Peters, Marjolein J; Duijts, Liesbeth; Jaddoe, Vincent W V; Tiemeier, Henning; Felix, Janine F; Willemsen, Gonneke; de Geus, Eco J C; Chu, Audrey Y; Levy, Daniel; Hwang, Shih-Jen; ... (2019). An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature communications, 10(1), p. 2581. Nature Publishing Group 10.1038/s41467-019-10487-4 <http://dx.doi.org/10.1038/s41467-019-10487-4Test>
Nature Communications, 10(1):2581. Nature Publishing Group
Liu, J, Carnero-Montoro, E, van Dongen, J, Lent, S, Nedeljkovic, I, Ligthart, S, Tsai, P-C, Martin, T C, Mandaviya, P R, Jansen, R, Peters, M J, Duijts, L, Jaddoe, V W V, Tiemeier, H, Felix, J F, Willemsen, G, de Geus, E J C, Chu, A Y, Levy, D, Hwang, S-J, Bressler, J, Gondalia, R, Salfati, E L, Herder, C, Hidalgo, B A, Tanaka, T, Moore, A Z, Lemaitre, R N, Jhun, M A, Smith, J A, Sotoodehnia, N, Bandinelli, S, Ferrucci, L, Arnett, D K, Grallert, H, Assimes, T L, Hou, L, Baccarelli, A, Whitsel, E A, van Dijk, K W, Amin, N, Uitterlinden, A G, Sijbrands, E J G, Franco, O H, Dehghan, A, Spector, T D, Dupuis, J, Hivert, M-F, Rotter, J I, Meigs, J B, Pankow, J S, van Meurs, J B J, Isaacs, A, Boomsma, D I, Bell, J T, Demirkan, A & van Duijn, C M 2019, ' An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis ', Nature Communications, vol. 10, no. 1, 2581, pp. 2581 . https://doi.org/10.1038/s41467-019-10487-4Test
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, 10:2581. Nature Publishing Group
Liu, J, Carnero-Montoro, E, van Dongen, J, Lent, S, Nedeljkovic, I, Ligthart, S, Tsai, P C, Martin, T C, Mandaviya, P R, Jansen, R, Peters, M J, Duijts, L, Jaddoe, V W V, Tiemeier, H, Felix, J F, Willemsen, G, de Geus, E J C, Chu, A Y, Levy, D, Hwang, S J, Bressler, J, Gondalia, R, Salfati, E L, Herder, C, Hidalgo, B A, Tanaka, T, Moore, A Z, Lemaitre, R N, Jhun, M A, Smith, J A, Sotoodehnia, N, Bandinelli, S, Ferrucci, L, Arnett, D K, Grallert, H, Assimes, T L, Hou, L, Baccarelli, A, Whitsel, E A, van Dijk, K W, Amin, N, Uitterlinden, A G, Sijbrands, E J G, Franco, O H, Dehghan, A, Spector, T D, Dupuis, J, Hivert, M F, Rotter, J I, Meigs, J B, Pankow, J S, van Meurs, J B J, Isaacs, A, Boomsma, D I, Bell, J T, Demirkan, A & van Duijn, C M 2019, ' An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis ', Nature Communications, vol. 10, 2581, pp. 1-11 . https://doi.org/10.1038/s41467-019-10487-4Test
Nature Communications, 10:2581, 1-11. Nature Publishing Group
Nat. Commun. 10:2581 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Epigenomics, Male, Netherlands Twin Register (NTR), medicine.medical_treatment, General Physics and Astronomy, 02 engineering and technology, Type 2 diabetes, UP-REGULATION, Epigenesis, Genetic, Glucose homeostasis, Homeostasis, Insulin, lcsh:Science, Genetics, Aged, 80 and over, Multidisciplinary, Middle Aged, 021001 nanoscience & nanotechnology, 3. Good health, Multidisciplinary Sciences, DNA methylation, Science & Technology - Other Topics, Epigenetics, Female, 0210 nano-technology, WAIST CIRCUMFERENCE, Metabolic Networks and Pathways, Adult, EXPRESSION, Science, 610 Medicine & health, Biology, Polymorphism, Single Nucleotide, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Young Adult, TYPE-2, SDG 3 - Good Health and Well-being, 360 Social problems & social services, Diabetes mellitus, medicine, GLYCEMIC TRAITS, Humans, Computer Simulation, Obesity, Transcriptomics, Aged, EPIGENOME-WIDE ASSOCIATION, Science & Technology, Gene Expression Profiling, DIABETES-MELLITUS, General Chemistry, DNA Methylation, medicine.disease, GENE, IRS2, BODY-MASS INDEX, 030104 developmental biology, Glucose, Diabetes Mellitus, Type 2, Gene Expression Regulation, lcsh:Q, CpG Islands, Genome-Wide Association Study, FASTING GLUCOSE

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c4c694350da37c4a64da57355aac00Test

المؤلفون: Marcus A. Tuke, Luigi Ferrucci, Jun Ding, Stefania Bandinelli, Timothy M. Frayling, Ann Zenobia Moore, Andrew R. Wood

المصدر: Aging Cell

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cell type, Mitochondrial DNA, Aging, DNA Copy Number Variations, Physiology, mitochondrial DNA, Biology, Mitochondrion, Bioinformatics, DNA, Mitochondrial, Blood cell, 03 medical and health sciences, Risk Factors, Diabetes mellitus, White blood cell, copy number, medicine, Diabetes Mellitus, Leukocytes, Humans, Whole blood, Aged, Aged, 80 and over, diabetes, Short Take, Cell Biology, Middle Aged, medicine.disease, cell distribution, 3. Good health, Mitochondria, all‐cause mortality, 030104 developmental biology, medicine.anatomical_structure, Phenotype, Female, Hemoglobin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe354242ae2091d5f68d9fbf4ef68633Test
http://europepmc.org/articles/PMC5770782Test

المؤلفون: Maho Morishima-Kawashima, A. Zenobia Moore, Min Suk Kang, Sungkwon Chung, Jeong Hill Park, Satoko Osawa, Seung-Hoon Baek, Diego E. Berman, Tae-Wan Kim, Hyun Ok Yang, Gilbert Di Paolo, Yasuo Ihara, Satoru Funamoto, Yoon Sun Chun, Natalie Landman

المصدر: Journal of Biological Chemistry. 288:20868-20882

مصطلحات موضوعية: Phosphatidylinositol 4,5-Diphosphate, Ginsenosides, Amyloid, Mice, Transgenic, CHO Cells, Receptors, Nerve Growth Factor, Biochemistry, Presenilin, Minor Histocompatibility Antigens, Mice, Structure-Activity Relationship, Enzyme activator, chemistry.chemical_compound, Cricetulus, Membrane Microdomains, Neurobiology, Cricetinae, mental disorders, Presenilin-1, medicine, Animals, Humans, Phosphatidylinositol, Molecular Biology, Lipid raft, Neurons, Amyloid beta-Peptides, Receptors, Notch, biology, Kinase, Cell Biology, medicine.disease, Molecular biology, Protein Structure, Tertiary, Cell biology, Enzyme Activation, Phosphotransferases (Alcohol Group Acceptor), chemistry, biology.protein, Amyloid Precursor Protein Secretases, Alzheimer's disease, Amyloid precursor protein secretase, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33cfc150180509e09a6e4620f794117Test
https://doi.org/10.1074/jbc.m112.445734Test

المؤلفون: John M. Starr, Anh N. Do, Michael M. Mendelson, Stella Iurato, Katri Räikkönen, Katharina Schramm, Devin Absher, Wolfgang Rathmann, Symen Ligthart, Elena Colicino, Ann Zenobia Moore, Annette Peters, Stefania Bandinelli, Matthias Wielscher, Ian J. Deary, Allan C. Just, Andrea A. Baccarelli, Golareh Agha, Michael Roden, Luigi Ferrucci, Roby Joehanes, Donna K. Arnett, Dena G. Hernandez, Christian Gieger, Chen Yao, Honghuang Lin, Joyce B. J. van Meurs, Carola Marzi, Melanie Waldenberger, Degui Zhi, Johan G. Eriksson, Riccardo E. Marioni, Oscar H. Franco, Toshiko Tanaka, Joel Schwartz, Daniel Levy, Holger Prokisch, André G. Uitterlinden, Sonja Kunze, Chunyu Liu, Tianxiao Huan, Marjo-Riitta Järvelin, James B. Meigs, Jari Lahti, Stella Aslibekyan, Harald Grallert, Pantel S. Vokonas, Christian Herder, Abbas Dehghan

المساهمون: Epidemiology, Internal Medicine

المصدر: JAMA Cardiol. 3, 463-472 (2018)
JAMA Cardiology
JAMA Cardiology, 3(6), 463-472. American Medical Association

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Cardiac & Cardiovascular Systems, TWIN, PARP-1, Genome-wide association study, 030204 cardiovascular system & hematology, GENE PROMOTER METHYLATION, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, DESIGN, Internal medicine, ABO blood group system, medicine, EPIGENETIC REGULATION, NLRC5, Science & Technology, business.industry, Hazard ratio, Methylation, medicine.disease, RHEUMATOID-ARTHRITIS, 3. Good health, 030104 developmental biology, CpG site, FAT, Rheumatoid arthritis, DNA methylation, Cohort, Cardiovascular System & Cardiology, MHC, INHIBITORS, Cardiology and Cardiovascular Medicine, business, Life Sciences & Biomedicine

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd317cc4a4bc2a0b19f1b3621ea2e540Test
https://doi.org/10.1001/jamacardio.2018.0510Test

المؤلفون: James B. Meigs, Jordana T. Bell, Marjolein J. Peters, James S. Pankow, Symen Ligthart, Dorret I. Boomsma, Toshiko Tanaka, Marie-France Hivert, Eric J.G. Sijbrands, Bertha Hidalgo, Joyce B. J. van Meurs, Elena Carnero-Montoro, Pei-Chien Tsai, Lifang Hou, van Dijk Kw, Cornelia M. van Duijn, Ko Willems van Dijk, Harald Grallert, Najaf Amin, Abbas Dehghan, Ann Zenobia Moore, Janine F. Felix, Tiphaine Martin, Aaron Isaacs, Jerome I. Rotter, Pooja R. Mandaviya, Rozenn N. Lemaitre, Henning Tiemeier, Eric A. Whitsel, Min A. Jhun, Ivana Nedeljkovic, Themistocles L. Assimes, Nona Sotoodehnia, Rick Jansen, Liesbeth Duijts, Shih-Jen Hwang, Jan Bressler, Vincent W. V. Jaddoe, Daniel Levy, André G. Uitterlinden, Audrey Y. Chu, Tim D. Spector, Luigi Ferrucci, Josée Dupuis, Ayse Demirkan, Samantha Lent, Rahul Gondalia, Donna K. Arnett, Oscar H. Franco, Jun Liu, Stefania Bandinelli, Jennifer A. Smith, Andrea A. Baccarelli, Elias Salfati, Christian Herder

المصدر: bioRxiv.

مصطلحات موضوعية: In silico, Diabetes mellitus, Insulin, medicine.medical_treatment, DNA methylation, medicine, Genomics, Methylation, Type 2 diabetes, Computational biology, Biology, medicine.disease, Epigenomics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b7f5baf635142fdb0912d97d5a4ca2Test
http://ora.ox.ac.uk/objects/uuidTest: