نتائج البحث - "Simone M. Goldinger"

1

Long-Term Response to Intermittent Binimetinib in Patients with NRAS-Mutant Melanoma

المؤلفون: Alexandra Valeska Matter, Simone M. Goldinger, Sara Micaletto, Ursula Urner-Bloch, Reinhard Dummer

المساهمون: University of Zurich, Dummer, Reinhard

المصدر: The Oncologist

مصطلحات موضوعية: Male, Proto-Oncogene Proteins B-raf, 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, MAPK/ERK pathway, Cancer Research, Skin Neoplasms, medicine.medical_treatment, 610 Medicine & health, Drug resistance, GTP Phosphohydrolases, Targeted therapy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Immune system, Cell Line, Tumor, Humans, Medicine, 1306 Cancer Research, Melanoma, Protein Kinase Inhibitors, Aged, business.industry, Kinase, 10177 Dermatology Clinic, Membrane Proteins, Binimetinib, medicine.disease, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Mutation, Cancer research, 2730 Oncology, Precision Medicine Clinic: Molecular Tumor Board, Benzimidazoles, Female, business

وصف الملف: 855_Matter_A._et_al._Long-Term_response_to_intermittent_binimetinib_in_patients_with_NRAS-mutant_Melanoma_the_Oncologist_2020.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145601bc949f4b0f83188d4b388aa2acTest
https://doi.org/10.1634/theoncologist.2019-0656Test

2

A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis

المصدر: Nature Medicine. 25:1243-1250

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c627227be1cd83e714203554c40967a9Test
https://doi.org/10.1038/s41591-019-0523-2Test

3

Incidence, features and management of radionecrosis in melanoma patients treated with cerebral radiotherapy and anti‐PD‐1 antibodies

المصدر: Pigment Cell Melanoma Res

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Bevacizumab, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Ipilimumab, Dermatology, Antibodies, Article, General Biochemistry, Genetics and Molecular Biology, Cohort Studies, Necrosis, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, medicine, Humans, Cumulative incidence, Radiation Injuries, Melanoma, business.industry, Incidence, Incidence (epidemiology), Brain, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Survival Analysis, Radiation therapy, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Multivariate Analysis, Cohort, Female, Neurosurgery, Radiology, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f18946bddd2aec8b60a7eecf640116Test
https://doi.org/10.1111/pcmr.12775Test

4

Clinical experience with combination BRAF/MEK inhibitors for melanoma with brain metastases: a real-life multicenter study

المؤلفون: Reinhard Dummer, Valerie C Amann, Anita Giobbie-Hurder, Simone M. Goldinger, Donald P. Lawrence, Lisa Zimmer, Joanna Mangana, Elisabeth Livingstone, Joshua Z. Drago, Tianqi Chen, Alfred Zippelius, Marco Siano, Ryan J. Sullivan

المصدر: Melanoma Research. 29:65-69

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Adolescent, Pyridones, MAP Kinase Kinase 1, Pyrimidinones, Dermatology, Nodular melanoma, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Oximes, Biomarkers, Tumor, medicine, Humans, Vemurafenib, Melanoma, Protein Kinase Inhibitors, Survival rate, Aged, Retrospective Studies, Trametinib, Cobimetinib, Brain Neoplasms, business.industry, Imidazoles, Dabrafenib, Binimetinib, Middle Aged, Prognosis, medicine.disease, Survival Rate, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Female, business, Follow-Up Studies, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7123c6e5c10387b054ed15296746eab0Test
https://doi.org/10.1097/cmr.0000000000000527Test

5

Peripheral Blood TCR Repertoire Profiling May Facilitate Patient Stratification for Immunotherapy against Melanoma

المؤلفون: Nadia Plantier, Sabrina A. Hogan, Simone M. Goldinger, Marieke I.G. Raaijmakers, Anais Courtier, Jean-François Mouret, Thi Dan Linh Nguyen-Kim, Phil F. Cheng, John B. A. G. Haanen, Mitchell P. Levesque, Solène Perez, Pia Kvistborg, Reinhard Dummer, Nicoletta F Jaberg-Bentele, Manuarii Manuel, Nicolas Pasqual

المساهمون: University of Zurich, Levesque, Mitchell P

المصدر: Cancer Immunology Research

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Skin Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Immunology, Receptors, Antigen, T-Cell, 610 Medicine & health, chemical and pharmacologic phenomena, Antibodies, Monoclonal, Humanized, Peripheral blood mononuclear cell, 03 medical and health sciences, symbols.namesake, Antineoplastic Agents, Immunological, 0302 clinical medicine, Internal medicine, medicine, Humans, CTLA-4 Antigen, 1306 Cancer Research, Progression-free survival, Melanoma, Fisher's exact test, Aged, 2403 Immunology, Receiver operating characteristic, 10042 Clinic for Diagnostic and Interventional Radiology, business.industry, T-cell receptor, 10177 Dermatology Clinic, Immunotherapy, Middle Aged, medicine.disease, Ipilimumab, Progression-Free Survival, 3. Good health, 030104 developmental biology, 030220 oncology & carcinogenesis, Monoclonal, symbols, Female, business

وصف الملف: Peripheral_blood_TCR_repertoire_profiling_may_facilitate.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2183a0c56e9ee4715bc5ea53f32f0b44Test
https://doi.org/10.1158/2326-6066.cir-18-0136Test

6

Outcome of melanoma patients with elevated LDH treated with first-line targeted therapy or PD-1-based immune checkpoint inhibition

المصدر: European journal of cancer (Oxford, England : 1990). 148

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Medizin, Gastroenterology, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Prospective cohort study, Immune Checkpoint Inhibitors, Melanoma, Aged, Retrospective Studies, business.industry, Confounding, Retrospective cohort study, Middle Aged, medicine.disease, Prognosis, Immune checkpoint, 3. Good health, Blockade, Survival Rate, 030104 developmental biology, Oncology, CTLA-4, 030220 oncology & carcinogenesis, Drug Therapy, Combination, Female, Immunotherapy, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7b5b295efc1524ab0bf2996f38c02fTest
https://pubmed.ncbi.nlm.nih.gov/33735811Test

7

Binimetinib in heavily pretreated patients with NRAS-mutant melanoma with brain metastases

المؤلفون: I Blume, Simone M. Goldinger, Sara Micaletto, A Valeska Matter, Reinhard Dummer, J. Mangana, Ursula Urner-Bloch, J Narainsing

المصدر: The British journal of dermatologyReferences. 182(2)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b8e43b892d5160c5ca0eb8afed48e3Test
https://pubmed.ncbi.nlm.nih.gov/31436845Test

8

Sarcoid-like reactions in patients receiving modern melanoma treatment

المؤلفون: Joanna Mangana, Mirjam C. Naegeli, Marjam J. Barysch, Simone M. Goldinger, Ralph P. Braun, Anna L. Frauchiger, Daniel Franzen, Mirjana Urosevic-Maiwald, Jivko Kamarachev, Reinhard Dummer, Florentia Dimitriou

المساهمون: University of Zurich, Dummer, Reinhard

المصدر: Melanoma Research

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Skin Neoplasms, Sarcoidosis, medicine.medical_treatment, Programmed Cell Death 1 Receptor, 610 Medicine & health, Dermatology, Disease, Targeted therapy, 2708 Dermatology, 030207 dermatology & venereal diseases, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Immune system, Cancer immunotherapy, medicine, melanoma, Humans, 1306 Cancer Research, Adverse effect, Protein Kinase Inhibitors, Aged, Retrospective Studies, business.industry, Melanoma, 10177 Dermatology Clinic, Retrospective cohort study, Middle Aged, medicine.disease, ORIGINAL ARTICLES: Clinical research, targeted therapy, Oncology, 030220 oncology & carcinogenesis, sarcoid-like reaction, 2730 Oncology, Immunotherapy, 10178 Clinic for Pneumology, business

وصف الملف: 755_Dimitriou_F._et_al._Sarcoid-like_reactions_in_patients_receiving_modern_melanoma_treatment_Melanoma_Res._2018.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338a9ad98b357f816497b9c7ee261928Test
http://europepmc.org/articles/PMC5929490Test

9

Clinical outcome of concomitant vs interrupted BRAF inhibitor therapy during radiotherapy in melanoma patients

المصدر: British Journal of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Radiation-Sensitizing Agents, Skin Neoplasms, medicine.medical_treatment, Medizin, Cohort Studies, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Oximes, Vemurafenib, Prospective cohort study, Melanoma, Aged, 80 and over, Imidazoles, Middle Aged, Treatment Outcome, 030220 oncology & carcinogenesis, Female, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Adolescent, Drug Administration Schedule, BRAF, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Humans, ddc:610, dabrafenib, Protein Kinase Inhibitors, radiotherapy, Aged, Retrospective Studies, business.industry, Dabrafenib, Retrospective cohort study, medicine.disease, Radiation therapy, radiation, 030104 developmental biology, Concomitant, Clinical Study, Skin cancer, business

وصف الملف: application/octet-stream

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e8f1dc9f3855c01558c2eeec19ddedTest
http://europepmc.org/articles/PMC5886123Test

10

A first‐in‐human phase I, multicenter, open‐label, dose‐escalation study of the oral RAF/VEGFR‐2 inhibitor (RAF265) in locally advanced or metastatic melanoma independent from BRAF mutation status

المؤلفون: Kevin B. Kim, Oliver Krieter, David F. McDermott, Keith T. Flaherty, Lyhping Lam, Shefali Kakar, Benjamin Izar, F. Stephen Hodi, Michael B. Atkins, Donald P. Lawrence, Simone M. Goldinger, William H. Sharfman, Reinhard Dummer, Ravi K. Amaravadi, Z. Tang, Jeffrey A. Sosman, Igor Puzanov

المصدر: Cancer Medicine

مصطلحات موضوعية: Placental growth factor, Oncology, Male, Cancer Research, Pathology, Angiogenesis, Pyridines, medicine.medical_treatment, 0302 clinical medicine, 030212 general & internal medicine, Molecular Targeted Therapy, Neoplasm Metastasis, BRAF wild‐type, Biomarker analysis, Melanoma, Original Research, Aged, 80 and over, Imidazoles, Middle Aged, Treatment Outcome, 030220 oncology & carcinogenesis, BRAF‐mutant, Immunohistochemistry, Female, Drug Monitoring, metastatic melanoma, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Maximum Tolerated Dose, Antineoplastic Agents, 03 medical and health sciences, Pharmacokinetics, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, RAF265, Adverse effect, Protein Kinase Inhibitors, Aged, Neoplasm Staging, business.industry, Growth factor, Clinical Cancer Research, medicine.disease, Pharmacodynamics, Mutation, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11750763d2c877bc35ec8877ec9195bTest
http://europepmc.org/articles/PMC5548886Test

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