المؤلفون: Vinit Kumar, Reshma Rani

المصدر: Pharmaceutical patent analyst. 9(6)

مصطلحات موضوعية: education.field_of_study, business.industry, Lactate dehydrogenase A, Cancer, General Medicine, Pharmacology, medicine.disease, Neoplasms, Medicine, Humans, Enzyme Inhibitors, Lactate Dehydrogenase 5, business, education

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960598c311231ab591a0b6f245697a25Test
https://pubmed.ncbi.nlm.nih.gov/33275465Test

المؤلفون: Reshma Rani, Vinit Kumar

المصدر: Journal of Medicinal Chemistry. 59:487-496

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Cancer, medicine.disease, Small molecule, Isozyme, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Enzyme, chemistry, Biochemistry, 030220 oncology & carcinogenesis, Lactate dehydrogenase, Drug Discovery, medicine, Molecular Medicine, Structure–activity relationship, Glycolysis, NAD+ kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b32e07fad20bef53eb1bf0f415fb1a95Test
https://doi.org/10.1021/acs.jmedchem.5b00168Test

المؤلفون: Reshma Rani, Vinit Kumar

المصدر: Future medicinal chemistry. 9(11)

مصطلحات موضوعية: 0301 basic medicine, Tumor glycolysis, Antineoplastic Agents, Biology, Small Molecule Libraries, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Lactate dehydrogenase, Neoplasms, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Pharmacology, L-Lactate Dehydrogenase, Drug discovery, Cancer, medicine.disease, Small molecule, Warburg effect, Isoenzymes, 030104 developmental biology, Biochemistry, chemistry, 030220 oncology & carcinogenesis, Cancer metabolism, Molecular Medicine, Lactate Dehydrogenase 5

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4402f7223aeb8ffc8096cf33f10e8360Test
https://pubmed.ncbi.nlm.nih.gov/28722474Test

المؤلفون: Ilaria Paterni, Carlotta Granchi, Filippo Minutolo, Reshma Rani

المصدر: Future Medicinal Chemistry. 5:1967-1991

مصطلحات موضوعية: Azoles, Indoles, Carboxylic Acids, Oxamic acid, Tumor cells, Plasma protein binding, Naphthalenes, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Humans, Protein Isoforms, Enzyme Inhibitors, 030304 developmental biology, Pharmacology, Oxamic Acid, 0303 health sciences, Invasive carcinoma, L-Lactate Dehydrogenase, Gossypol, Cancer, medicine.disease, Ligand (biochemistry), Small molecule, 3. Good health, Isoenzymes, Kinetics, Biochemistry, 030220 oncology & carcinogenesis, Quinolines, Cancer research, Molecular Medicine, Lactate Dehydrogenase 5, Pharmacophore, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f94a5cefd494bfd6b12864170268969Test
https://doi.org/10.4155/fmc.13.151Test

المؤلفون: John R. P. Knight, Reshma Rani, Filippo Minutolo, Carlotta Granchi, Jo Milner, Simon J. Allison, Roger M. Phillips

المصدر: Oncogenesis
Allison, S J, Knight, J R P, Granchi, C, Rani, R, Minutolo, F, Milner, J & Phillips, R M 2014, ' Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways ', Oncogenesis, vol. 3, e102 . https://doi.org/10.1038/oncsis.2014.16Test

مصطلحات موضوعية: p53, Cancer Research, RM, cancer metabolism, Nicotinamide adenine dinucleotide, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Oxidoreductase, medicine, Molecular Biology, 030304 developmental biology, NAD+/NADH, chemistry.chemical_classification, 0303 health sciences, Manchester Cancer Research Centre, biology, Sirtuin 1, ResearchInstitutes_Networks_Beacons/mcrc, LDH-A, apoptosis, Cancer, Cell cycle, medicine.disease, combinatorial anticancer therapy, 3. Good health, Cell biology, chemistry, Biochemistry, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Original Article, NAD+ kinase, Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42469bcc181693abcd2f39538ba2f75fTest
https://pubmed.ncbi.nlm.nih.gov/24819061Test

المؤلفون: Filippo Minutolo, G.J. Peters, Reshma Rani, Kees Smid, Richard J. Honeywell, Lg Leon, Elisa Giovannetti, Carlotta Granchi, Amir Avan, Mina Maftouh, Rocco Sciarrillo, Niccola Funel, Ugo Boggi

المساهمون: Medical oncology laboratory, Hematology laboratory, CCA - Innovative therapy

المصدر: Maftouh, M, Avan, A, Sciarrillo, R, Granchi, C, Leon, L G, Rani, R, Funel, N, Smid, K, Honeywell, R J, Boggi, U, Minutolo, F, Peters, G J & Giovannetti, E 2014, ' Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia ', British Journal of Cancer, vol. 110, no. 1, pp. 172-182 . https://doi.org/10.1038/bjc.2013.681Test
British Journal of Cancer
British Journal of Cancer, 110(1), 172-182. Nature Publishing Group

مصطلحات موضوعية: Cancer Research, Deoxycytidine, chemistry.chemical_compound, 0302 clinical medicine, lactate dehydrogenase inhibitors, Cell Movement, Antineoplastic Combined Chemotherapy Protocols, Tumor Cells, Cultured, AC133 Antigen, Enzyme Inhibitors, 0303 health sciences, education.field_of_study, gemcitabine, Polycomb Repressive Complex 2, Drug Synergism, Cell Hypoxia, 3. Good health, Isoenzymes, Oncology, Biochemistry, 030220 oncology & carcinogenesis, medicine.symptom, Carcinoma, Pancreatic Ductal, medicine.drug, Lactate dehydrogenase A, pancreatic ductal adenocarcinoma, Down-Regulation, Biology, 03 medical and health sciences, Antigens, CD, Cell Line, Tumor, Spheroids, Cellular, Lactate dehydrogenase, Pancreatic cancer, medicine, Animals, Enhancer of Zeste Homolog 2 Protein, RNA, Messenger, education, Molecular Diagnostics, Glycoproteins, 030304 developmental biology, L-Lactate Dehydrogenase, hypoxia, Cell growth, Hypoxia (medical), medicine.disease, Gemcitabine, Pancreatic Neoplasms, chemistry, Anaerobic glycolysis, Apoptosis, Metalloproteases, Cancer research, Lactate Dehydrogenase 5, Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbf400bb12fc68fe8e01060e03b3c6bTest
http://hdl.handle.net/11568/271135Test

المؤلفون: P.P. Gupta, Sham M. Sondhi, Reshma Rani, Satyam Kumar Agrawal, A. K. Saxena, Jaiveer Singh

المصدر: European journal of medicinal chemistry. 45(2)

مصطلحات موضوعية: Male, medicine.drug_class, Stereochemistry, Anti-Inflammatory Agents, Antineoplastic Agents, Pharmacology, Carrageenan, Chemical synthesis, Anti-inflammatory, Structure-Activity Relationship, In vivo, Neuroblastoma, Cell Line, Tumor, Drug Discovery, medicine, Structure–activity relationship, Animals, Edema, Humans, Cytotoxicity, Cell Proliferation, Chemistry, Organic Chemistry, General Medicine, Ibuprofen, medicine.disease, In vitro, Rats, Acridines, Female, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10ab777649036fce273687eca402845Test
https://pubmed.ncbi.nlm.nih.gov/19926172Test