المؤلفون: Nicole Bilek, Violaine Saint-André, Elisa Nemes, Stanley Kimbung Mbandi, Elizabeth Filander, Munyaradzi Musvosvi, Humphrey Mulenga, Matthew L. Albert, Alba Llibre, Vincent Rouilly, Hadn Africa, Céline Posseme, Simba Mabwe, Nikaïa Smith, Vincent Bondet, Thomas J. Scriba, Pierre Bost, Darragh Duffy, Bruno Charbit

المساهمون: Immunologie Translationnelle - Translational Immunology lab, Institut Pasteur [Paris] (IP), Datactix, University of Cape Town, Ecole Doctorale Complexité du Vivant (ED515), Sorbonne Université (SU), Cytometrie et Biomarqueurs – Cytometry and Biomarkers (UTechS CB), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Département de Biologie Computationnelle - Department of Computational Biology, Insitro [San Francisco], This study was funded by the Bill and Melinda Gates Foundation (OPP1114368 and OPP1204624), with additional support from the French Government’s Investissement d’Avenir Program, Laboratoire d’Excellence 'Milieu Intérieur' Grant ANR-10-LABX-69-01. AL was supported by the Fondation Recherche Médicale (SPF20170938617) and the European Commision (H2020-MSCA-IF 2018, 841729). NS was supported by an Institut Pasteur Roux Cantarini fellowship., We thank the UTechS CB of the Center for Translational Research, Institut Pasteur for supporting Nanostring analysis. DD thanks Immunoqure for provision of the mAbs under an MTA for the Simoa IFN-α assay. We are grateful to the study participants and the SATVI clinical and laboratory teams., ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010), Institut Pasteur [Paris], Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)

المصدر: Frontiers in Immunology
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.897193⟩

مصطلحات موضوعية: Tuberculosis, Immunology, Disease, Mycobacterium tuberculosis, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigen, Interleukin 1 (IL-1), Medicine, Immunology and Allergy, Interleukin 1 Receptor antagonist (IL-1ra), 030304 developmental biology, Systems immunology, 0303 health sciences, Immunometabolism, biology, business.industry, biology.organism_classification, medicine.disease, 3. Good health, Granzyme, biology.protein, [SDV.IMM]Life Sciences [q-bio]/Immunology, Tumor necrosis factor alpha, business, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7d66d578f973127265656a16479c84Test
https://doi.org/10.3389/fimmu.2022.897193Test

المؤلفون: Lluis Quintana-Murci, Bruno Charbit, Antonio Rausell, Darragh Duffy, Caron B, Matthew L. Albert, Etienne Patin, Maxime Rotival

المساهمون: The Clinical Bioinformatics laboratory (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Génétique Evolutive Humaine - Human Evolutionary Genetics, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Cytometrie et Biomarqueurs – Cytometry and Biomarkers (UTechS CB), Institut Pasteur [Paris], Insitro [San Francisco], Chaire Génomique humaine et évolution, Collège de France (CdF (institution)), Immunologie Translationnelle - Translational Immunology lab, Service de génétique moléculaire [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), This work benefited from support of the French government's Invest in the Future programme. This programme is managed by the Agence Nationale de la Recherche, reference ANR-10-LABX-69-01. The Clinical Bioinformatics Laboratory of the Imagine Institute was partly supported by the French National Research Agency (ANR) 'Investissements d’Avenir' Program (Grant ANR-10-IAHU-01)., ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010), ANR-10-IAHU-0001,Imagine,Institut Hospitalo-Universitaire Imagine(2010), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), HIBIO [South San Francisco], Collège de France - Chaire Génomique humaine et évolution, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), The study is sponsored by Institut Pasteur (Pasteur ID-RCB Number: 2012-A00238-35) and was conducted as a single-center interventional study without an investigational product. This work benefited from support of the French government’s Invest in the Future program. This program is managed by the Agence Nationale de la Recherche, reference ANR-10-LABX-69-01. The Clinical Bioinformatics Laboratory of the Imagine Institute was partly supported by the French National Research Agency (ANR) 'Investissements d’Avenir' Program (Grant ANR-10-IAHU-01)., The Milieu Intérieur Consortium is composed of the following team leaders: Laurent Abel (Hôpital Necker), Andres Alcover (Institut Pasteur), Hugues Aschard (Institut Pasteur), Philippe Bousso (Institut Pasteur), Nollaig Bourke (Trinity College Dublin), Petter Brodin (Karolinska Institutet), Pierre Bruhns (Institut Pasteur), Nadine Cerf-Bensussan (INSERM UMR 1163 – Institut Imagine), Ana Cumano (Institut Pasteur), Caroline Demangel (Institut Pasteur), Christophe d’Enfert (Institut Pasteur), Ludovic Deriano (Institut Pasteur), Marie-Agnès Dillies (Institut Pasteur), James Di Santo (Institut Pasteur), Françoise Dromer (Institut Pasteur), Gérard Eberl (Institut Pasteur), Jost Enninga (Institut Pasteur), Jacques Fellay (EPFL, Lausanne), Ivo Gomperts-Boneca (Institut Pasteur), Milena Hasan (Institut Pasteur), Magnus Fontes (Institut Roche), Gunilla Karlsson Hedestam (Karolinska Institutet), Serge Hercberg (Université Paris 13), Molly A Ingersoll (Institut Pasteur), Rose Anne Kenny (Trinity College Dublin), Olivier Lantz (Institut Curie), Frédérique Michel (Institut Pasteur), Hugo Mouquet (Institut Pasteur), Cliona O'Farrelly (Trinity College Dublin), Etienne Patin (Institut Pasteur), Sandra Pellegrini (Institut Pasteur), Stanislas Pol (Hôpital Côchin), Antonio Rausell (INSERM UMR 1163 – Institut Imagine), Frédéric Rieux-Laucat (INSERM UMR 1163 – Institut Imagine), Lars Rogge (Institut Pasteur), Anavaj Sakuntabhai (Institut Pasteur), Olivier Schwartz (Institut Pasteur), Benno Schwikowski (Institut Pasteur), Spencer Shorte (Institut Pasteur), Frédéric Tangy (Institut Pasteur), Antoine Toubert (Hôpital Saint-Louis), Mathilde Touvier (Université Paris 13), Marie-Noëlle Ungeheuer (Institut Pasteur), Christophe Zimmer (Institut Pasteur), Matthew L. Albert (Insitro)§, Darragh Duffy (Institut Pasteur)§, Lluis Quintana-Murci (Institut Pasteur)§. § co-coordinators of the Milieu Intérieur Consortium., PATIN, Etienne, Laboratoires d'excellence - GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE - - MILIEU INTERIEUR2010 - ANR-10-LABX-0069 - LABX - VALID, Instituts Hospitalo-Universitaires - Institut Hospitalo-Universitaire Imagine - - Imagine2010 - ANR-10-IAHU-0001 - IAHU - VALID, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)

المصدر: Genome Medicine
Genome Medicine, 2022, 14 (1), pp.28. ⟨10.1186/s13073-022-01032-y⟩

مصطلحات موضوعية: medicine.medical_treatment, Health Status, Primary Immunodeficiency Diseases, Quantitative Trait Loci, immune variability, Quantitative trait locus, Biology, [SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics, Polymorphism, Single Nucleotide, Blood cell, 03 medical and health sciences, 0302 clinical medicine, Immune system, immune cells, Genetics, medicine, Humans, Receptor, Molecular Biology, Genetics (clinical), 030304 developmental biology, Genetic association, 2. Zero hunger, 0303 health sciences, pQTL, Blood Proteins, medicine.disease, Blood proteins, 3. Good health, Cytokine, medicine.anatomical_structure, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, 030220 oncology & carcinogenesis, Immunology, Primary immunodeficiency, Molecular Medicine, [SDV.IMM]Life Sciences [q-bio]/Immunology, plasma proteins, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1723e6d253b7b5ce9a43d2762feae6Test
https://pubmed.ncbi.nlm.nih.gov/35264221Test

المؤلفون: Françoise Dromer, Antonio Rausell, Elizabeth Filander, Bruno Charbit, Odile Gelpi, Kalla Astrom, Stanislas Pol, Elisa Nemes, Vincent Rouilly, Mark Hatherill, Hadn Africa, Humphrey Mulenga, Ana Cumano, Hugo Mouquet, Etienne Patin, Lluis Quintana-Murci, Lungisa Jaxa, Laurent Abel, Milena Hasan, James P. Di Santo, Claude Leclerc, Spencer L. Shorte, Vassili Soumelis, Stéphanie Thomas, Caroline Demangel, Mathilde Touvier, Andrés Alcover, Thomas J. Scriba, Matthew L. Albert, Anavaj Sakuntabhai, Hugues Aschard, Nikaïa Smith, Serge Hercberg, Darragh Duffy, Jost Enninga, Olivier Schwartz, Ivo Gomperts-Boneca, Marie-Noëlle Ungeheuer, Simbarashe Mabwe, Ludovic Deriano, Frédéric Tangy, Gérard Eberl, Sandra Pellegrini, Antoine Toubert, Lars Rogge, Stephanus T. Malherbe, Gerhard Walzl, Michele Tameris, Munyaradzi Musvosvi, Alba Llibre, Benno Schwikowski, Olivier Lantz, Nicole Bilek, Philippe Bousso, Pierre Bruhns, Jacques Fellay, Eric Tartour

المصدر: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Tuberculosis, Enzyme-Linked Immunosorbent Assay, Disease, Asymptomatic, QuantiFERON, Mycobacterium tuberculosis, Interferon-gamma, 03 medical and health sciences, 0302 clinical medicine, Antigen, Latent Tuberculosis, medicine, Humans, 030212 general & internal medicine, Online only Articles, Whole blood, biology, business.industry, immune profiling, biomarkers, patient stratification, bacterial infections and mycoses, medicine.disease, biology.organism_classification, cytokines, 3. Good health, AcademicSubjects/MED00290, 030104 developmental biology, Infectious Diseases, Cohort, Immunology, medicine.symptom, business, Interferon-gamma Release Tests

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973c9681e36288da04877fa23cf1cb9cTest
https://doi.org/10.1093/cid/ciaa1562Test

المؤلفون: Elisa Desmetz, Lluis Quintana-Murci, Mathilde Touvier, Léopold Fezeu, Serge Hercberg, Nathalie Druesne-Pecollo, Chantal Julia, Darragh Duffy, Pilar Galan, Mélanie Deschasaux, Paule Latino-Martel, Valentin Partula, Olivier Lantz, Bernard Srour, Stanislas Mondot, Emmanuelle Kesse-Guyot, Eloi Chazelas, Matthew L. Albert

المساهمون: Equipe 3: EREN- Equipe de Recherche en Epidémiologie Nutritionnelle (CRESS - U1153), Université Sorbonne Paris Nord-Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Paris Cité (UPCité), Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Immunité et cancer (U932), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), CIC1428 IGR-CURIE, Génétique Evolutive Humaine - Human Evolutionary Genetics, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Chaire Génomique humaine et évolution, Collège de France (CdF (institution)), Department of Immunology and Infectious Diseases, Insitro [San Francisco], Immunobiologie des Cellules dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), NutriNet-Santé study was supported by the following French public institutions: Ministère de la Santé, Santé Publique France, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA), Conservatoire National des Arts et Métiers (CNAM) and Université Paris-XIII Nord. The Milieu Intérieur Consortium was supported by French Government’s Investissement d’Avenir Program, Laboratoire d’Excellence 'Milieu Intérieur' Grant ANR-10-LABX-69-01. Valentin Partula was funded by Ph.D. a grant from the Labex Milieu Interieur, and is provided financial support from École doctorale 474 Frontières de l’Innovation en Recherche et Education – Programme Bettencourt., Milieu intérieur, ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Collège de France - Chaire Génomique humaine et évolution, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université de Paris (UP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Curie [Paris]

المصدر: The American Journal of Clinical Nutrition
The American Journal of Clinical Nutrition, Oxford University Press, 2020, ⟨10.1093/ajcn/nqaa063⟩
The American Journal of Clinical Nutrition, 2020, ⟨10.1093/ajcn/nqaa063⟩
American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, American Society for Nutrition, 2020, ⟨10.1093/ajcn/nqaa063⟩

مصطلحات موضوعية: Adult, Dietary Fiber, Male, medicine.medical_specialty, Colorectal cancer, prospective cohort, Medicine (miscellaneous), 030209 endocrinology & metabolism, Type 2 diabetes, dietary fibers, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Neoplasms, Internal medicine, Vegetables, cancers, medicine, Humans, Prospective Studies, 030212 general & internal medicine, Prospective cohort study, 2. Zero hunger, Nutrition and Dietetics, Proportional hazards model, business.industry, Public health, Cancer, Middle Aged, medicine.disease, mortality, cardiovascular diseases, 3. Good health, Diabetes Mellitus, Type 2, Fruit, Cohort, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, type 2 diabetes, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b5ab88d73b3767ca0ca25219a88c18Test
https://doi.org/10.1093/ajcn/nqaa063Test

المؤلفون: Magnus Fontes, Sergio Ley Acosta, Ellie Guardino, Sanjeev Mariathasan, Matthew L. Albert, Vincent Rouilly, Christian Hammer, G. Scott Chandler, Jonathan Rosenberg, J. D. Carroll, Ira Mellman, Antonia Kwan, Tushar Bhangale, Haiyin Chen-Harris, Julie Hunkapiller, Thomas Powles, Zia Khan, F. Di Nucci

المصدر: Proceedings of the National Academy of Sciences. 117:12288-12294

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Multidisciplinary, Bladder cancer, business.industry, Cancer, Atopic dermatitis, Vitiligo, medicine.disease, Immune checkpoint, Atezolizumab, Psoriasis, Internal medicine, Medicine, Adverse effect, business, Cancer immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f7a18fa18e8a42336818349d0d4293Test
https://doi.org/10.1073/pnas.1922867117Test

المؤلفون: Vincent Bondet, Eric Savier, Olivier Scatton, Clémence Hollande, Matthew L. Albert, Jeremy Boussier, Stanislas Pol, Alba Llibre, Vincent Mallet, Estelle Mottez, Tan Phuc Buivan, Bruno Charbit, Frédéric Charlotte, Darragh Duffy

المساهمون: Université Paris Cité (UPCité), Immunobiologie des Cellules dendritiques, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'hépatologie médicale [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service d'Anatomie et cytologie pathologiques = Service de Pathologie [CHU Pitié-Salpêtrière] (ACP), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service de Chirurgie Digestive, Hépato-Bilio-pancréatique et Transplantation Hépatique [CHU Pitié-Salpétrière], Fondation ARC pour la Recherche sur le Cancer, BONDET, Vincent, Université de Paris (UP), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'Anatomie et cytologie pathologiques [CHU Pitié-Salpêtrière] (ACP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)

المصدر: Liver Cancer International
Liver Cancer International, 2021, pp.Online Version of Record before inclusion in an issue. ⟨10.1002/lci2.36⟩

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Population, Pharmaceutical Science, Chronic liver disease, Gastroenterology, sitagliptin, 03 medical and health sciences, 0302 clinical medicine, dipeptidyl peptidase 4, Internal medicine, medicine, Pharmacology (medical), neoadjuvant therapy, education, Adverse effect, Neoadjuvant therapy, Dipeptidyl peptidase-4, 030304 developmental biology, 0303 health sciences, education.field_of_study, business.industry, hepatocellular carcinoma, medicine.disease, 3. Good health, [SDV] Life Sciences [q-bio], Complementary and alternative medicine, 030220 oncology & carcinogenesis, Sitagliptin, Hepatocellular carcinoma, business, Adjuvant, leucocyte trafficking, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a52eafb8542a3480df06b3e633a8c19Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-03384283/file/Safety_of_sitagliptin_in_treatment_of_hepatocellul.pdfTest

المؤلفون: Christian Hammer, Sergio Ley Acosta, Matthew L. Albert, Julie Hunkapiller, J. D. Carroll, Chandler Gs, Tushar Bhangale, Ira Mellman, Di Nucci F, Zia Khan, Mark I McCarthy, Maiya

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, endocrine system, endocrine system diseases, Science, General Physics and Astronomy, Genome-wide association study, Autoimmunity, Triple Negative Breast Neoplasms, Kaplan-Meier Estimate, Lower risk, Antibodies, Monoclonal, Humanized, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, Hypothyroidism, Meta-Analysis as Topic, Atezolizumab, Internal medicine, Genetic variation, medicine, Genetics, Humans, Adverse effect, Cancer genetics, Immune Checkpoint Inhibitors, Triple-negative breast cancer, Retrospective Studies, Multidisciplinary, business.industry, Cancer, Genetic Variation, General Chemistry, medicine.disease, Thyroid Diseases, Blockade, 030104 developmental biology, Risk factors, 030220 oncology & carcinogenesis, Immunology, Thyroid autoimmunity, Female, Immunotherapy, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f68077b105fa838ab15c65a5b902caaTest
http://europepmc.org/articles/PMC8184890Test

المؤلفون: Ansgar Seyfferth, Silvia Sánchez-Ramón, Matthew L. Albert, Marta Tejera-Alhambra, Rebeca Pérez de Diego, Maria Angel García Martínez, Lidia Fernández-Paredes, Bárbara Alonso, Joaquín Navarro, Jérémie Decalf, José Carlos Álvarez Cermeño, Clara de Andrés, Celia Oreja-Guevara, Rafael Arroyo, Roberto Alvarez Lafuente, Luisa M. Villar, Armanda Casrouge, Margarita López Trascasa

المصدر: Clinical Immunology. 181:43-50

مصطلحات موضوعية: Chemokine CCL11, 0301 basic medicine, Oncology, medicine.medical_specialty, Dipeptidyl Peptidase 4, Immunology, Inflammation, Disease, Chemokine CXCL9, Risk Assessment, 03 medical and health sciences, Multiple Sclerosis, Relapsing-Remitting, 0302 clinical medicine, Immune system, Internal medicine, medicine, Humans, Immunology and Allergy, CXCL10, Chemokine CCL4, Chemokine CCL5, Chemokine CCL2, Epidermal Growth Factor, Hepatocyte Growth Factor, business.industry, Interleukin-7, Multiple sclerosis, Decision Trees, Multiple Sclerosis, Chronic Progressive, Prognosis, medicine.disease, Chemokine CXCL10, Interleukin 1 Receptor Antagonist Protein, Early Diagnosis, 030104 developmental biology, Area Under Curve, Case-Control Studies, Multivariate Analysis, Risk stratification, Fibroblast Growth Factor 2, Nervous System Diseases, medicine.symptom, business, Biomarkers, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874bdeab285dbe1f86dfdc3b1af2d8fcTest
https://doi.org/10.1016/j.clim.2017.05.019Test

المؤلفون: Arn M. J. M. van den Maagdenberg, Stewart Wiseman, David Hunt, Gisela M. Terwindt, Isabelle Melki, Sarah McGlasson, Tracy A Briggs, Darragh Duffy, Alexandre Belot, Marie-Alexandra Alyanakian, Mathieu P Rodero, Flore Rozenberg, Pierre Quartier, Christina Hertel, Vincent Bondet, Isabelle Meyts, N. Bellon, Benedicte Neven, Adrian Hayday, Frédéric Rieux-Laucat, Nadine Pelzer, Jérémie Decalf, Matthew L. Albert, Lucile Musset, Joanna M. Wardlaw, Marie Hully, Gillian I. Rice, Marie-Louise Frémond, Scott W Werneke, Brigitte Bader-Meunier, Christine Barnerias, Christine Bodemer, Yanick J. Crow, Yoann Rose, Isabelle Desguerre

المساهمون: Laboratory of neurogenetics and neuroinflammation (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunobiologie des Cellules dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre For Clinical Brain Sciences - Neuroimaging Sciences [Edinburgh, U.K.] (CCBS), University of Edinburgh, Medical Research Council (MRC) Human Genetics Unit [Edinburgh], MRC Institute of Genetics and Molecular Medicine [Edinburgh] (IGMM), University of Edinburgh-Medical Research Council-University of Edinburgh-Medical Research Council, Manchester Centre for Genomic Medicine (MCGM), Manchester Academic Health Science Centre (MAHSC), University of Manchester [Manchester]-University of Manchester [Manchester]-Faculty of Biology, Medicine and Health [Manchester, UK], University of Manchester [Manchester]-Manchester University NHS Foundation Trust (MFT)-St Mary's Hospital Manchester, Service d'immuno-hématologie pédiatrique [CHU Necker], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de neurologie pédiatrique [CHU Necker], Service de dermatologie [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Réponse immunitaire innée dans les maladies infectieuses et auto-immunes – Innate immunity in infectious and autoimmune diseases, Centre International de Recherche en Infectiologie - UMR (CIRI), Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Hospices Civils de Lyon (HCL), Division of Evolution and Genomic Science [Manchester], School of Biological Sciences [Manchester]-Faculty of Biology, Medicine and Health [Manchester], Department of Neurology, Leiden University Medical Center (LUMC), Departments of Human Genetics & Neurology, General Paediatrics, Infectious Disease and Internal Medicine Department [Robert-Debré], Hôpital Robert Debré, Department of Microbiology and Immunology, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Pediatric Immunodeficiencies, University Hospitals Leuven [Leuven], Service d'Immunologie [CHU Pitié-Salpétrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), ImmunoQure AG, Peter Gorer Department of Immunobiology, King‘s College London, The Francis Crick Institute [London], Université Paris Descartes - Paris 5 (UPD5), Service de Virologie [CHU Cochin], Hôpital Cochin [AP-HP], Service de Génétique Médicale [CHU Necker], Y.J. Crow acknowledges support from the European Research Council (fellowshipGA 309449, fellowship), the European Leukodystrophy Association (ELA 2012-008I1), and a state subsidy managed by the Agence Nationale de la Recherche (ANR, France) under the 'Investments for the Future' program bearing the reference ANR-10-IAHU-01. Y.J. Crow and D. Duffy acknowledge support from the ANR (CE17001002).Y.L. Crow and A.M.J.M. van den Maagdenberg acknowledge the EU FP7 project NIM BL(241779). D. Duffy acknowledges funding from a PasteurInnov grant and the EU FP7project PoC-HCV (261365) for development of Simoa assays. S. Wiseman andJ. Wardlaw acknowledge funding from Lupus UK. A. Hayday acknowledges supportfrom the Wellcome Trust (grant 106292/Z/14/Z). F. Rieux-Laucat and Y.J. Crow acknowledgethe ANR (ANR-14-CE14-0026-01 'Lumugene'). D. Hunt is supported bythe Wellcome Trust., ANR-10-IAHU-0001,Imagine,Institut Hospitalo-Universitaire Imagine(2010), ANR-14-CE14-0026,Lumugene,Etude de familles multiplex de lupus pour l'identification de nouveaux gènes à fort impact phénotypique : de la découvertes des gènes à leurs fonctions(2014), European Project: 241779,EC:FP7:HEALTH,FP7-HEALTH-2009-single-stage,NIMBL(2010), European Project: 261365,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,SPHINX(2010), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Academic Unit of Medical Genetic, University of Manchester [Manchester], Medical Research Council Institute of Genetics and Molecular Medicine [Edinburgh, UK], Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Edinburgh-MRC Institute of Genetics and Molecular Medicine [Edinburgh] (IGMM), University of Edinburgh-Medical Research Council-Medical Research Council, Manchester Centre for Genomic Medicine [Manchester, UK] (MCGM), St Mary's Hospital Manchester-Manchester Academic Health Science Centre (MAHSC), University of Manchester [Manchester]-University of Manchester [Manchester]-Manchester University NHS Foundation Trust (MFT)-Faculty of Biology, Medicine and Health [Manchester, UK], Vougny, Marie-Christine, Instituts Hospitalo-Universitaires - Institut Hospitalo-Universitaire Imagine - - Imagine2010 - ANR-10-IAHU-0001 - IAHU - VALID, Appel à projets générique - Etude de familles multiplex de lupus pour l'identification de nouveaux gènes à fort impact phénotypique : de la découvertes des gènes à leurs fonctions - - Lumugene2014 - ANR-14-CE14-0026 - Appel à projets générique - VALID, Nuclease Immune Mediated Brain and Lupus-like conditions (NIMBL): natural history, pathophysiology, diagnostic and therapeutic modalities with application to other disorders of autoimmunity - NIMBL - - EC:FP7:HEALTH2010-06-01 - 2013-11-30 - 241779 - VALID, Spontaneous clearance in Patients acutely infected with HCV - Immune profiling, Novel biomarkers and X-omics approaches - SPHINX - - EC:FP7:HEALTH2010-11-01 - 2014-04-30 - 261365 - VALID, Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Universiteit Leiden-Universiteit Leiden, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)

المصدر: Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2017, 214 (5), pp.1547-1555. ⟨10.1084/jem.20161451⟩
The Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2017, 214 (5), pp.1547-1555. ⟨10.1084/JEM.20161451⟩
Journal of Experimental Medicine, 214(5), 1547-1555
Journal of Experimental Medicine, 2017, 214 (5), pp.1547-1555. ⟨10.1084/jem.20161451⟩
Rodero, M P, Decalf, J, Bondet, V, Hunt, D, Rice, G, Werneke, S, McGlasson, S L, Alyanakian, M-A, Bader-Meunier, B, Barnerias, C, Bellon, N, Belot, A, Bodemer, C, Briggs, T, Desguerre, I, Frémond, M-L, Hully, M, van den Maagdenberg, A M J M, Melki, I, Meyts, I, Musset, L, Pelzer, N, Quartier, P, Terwindt, G M, Wardlaw, J, Wiseman, S, Rieux-Laucat, F, Rose, Y, Neven, B, Hertel, C, Hayday, A, Albert, M L, Rozenberg, F, Crow, Y & Duffy, D 2017, ' Detection of interferon alpha protein reveals differential levels and cellular sources in disease ', Journal of Experimental Medicine, vol. 214, no. 5, pp. 1547–1555 . https://doi.org/10.1084/jem.20161451Test
Rodero, M P, Decalf, J, Bondet, V, Hunt, D, Rice, G I, Werneke, S, McGlasson, S L, Alyanakian, M-A, Bader-Meunier, B, Barnerias, C, Bellon, N, Belot, A, Bodemer, C, Briggs, T A, Desguerre, I, Frémond, M-L, Hully, M, van den Maagdenberg, A MJM, Melki, I, Meyts, I, Musset, L, Pelzer, N, Quartier, P, Terwindt, G M, Wardlaw, J, Wiseman, S, Rieux-Laucat, F, Rose, Y, Neven, B, Hertel, C, Hayday, A, Albert, M L, Rozenberg, F, Crow, Y J & Duffy, D 2017, ' Detection of interferon alpha protein reveals differential levels and cellular sources in disease ', Journal of Experimental Medicine . https://doi.org/10.1084/jem.20161451Test

مصطلحات موضوعية: 0301 basic medicine, [SDV.IMM] Life Sciences [q-bio]/Immunology, Technical Advances, [SDV]Life Sciences [q-bio], T-Lymphocytes, medicine.medical_treatment, Immunology, Alpha interferon, Enzyme-Linked Immunosorbent Assay, Disease, Biology, medicine.disease_cause, Sensitivity and Specificity, Severity of Illness Index, Autoimmunity, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Lupus Erythematosus, Systemic, Immunology and Allergy, Research Articles, ComputingMilieux_MISCELLANEOUS, 030203 arthritis & rheumatology, Lupus erythematosus, Autoantibody, Interferon-alpha, medicine.disease, 3. Good health, 030104 developmental biology, Cytokine, Interferon Regulatory Factors, [SDV.IMM]Life Sciences [q-bio]/Immunology, Vesicular Stomatitis, Interferon regulatory factors

وصف الملف: application/pdf; applicaton/octet-stream; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded482e959c5a43ec09e83d04712971dTest
https://doi.org/10.1084/jem.20161451Test

المؤلفون: Matthew L. Albert, Christian Hammer, Zia Khan, Ellie Guardino, G. Scott Chandler

المصدر: Genome Medicine
Genome Medicine, Vol 11, Iss 1, Pp 1-3 (2019)

مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, medicine.medical_treatment, Systems biology, lcsh:Medicine, Bioinformatics, Germline, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antineoplastic Agents, Immunological, Neoplasms, Genetics, medicine, Animals, Humans, Genetic Testing, Precision Medicine, Receptors, Immunologic, Adverse effect, Molecular Biology, Genetics (clinical), business.industry, lcsh:R, Comment, Cancer, Immunotherapy, biochemical phenomena, metabolism, and nutrition, medicine.disease, Human genetics, Immune checkpoint, lcsh:Genetics, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, bacteria, business, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffcf1df1efa465e3cc9f63098e3b019Test
http://europepmc.org/articles/PMC6585053Test