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المؤلفون: Peter J. Teravskis, Michael K. Lee, Carmen Nanclares, Balvindar Singh, Alfonso Araque, Emmanuel Okematti, Héctor A. Martell-Martínez, Joyce Meints, Mathew A. Sherman, Sylvain Lesné, Michael A. Benneyworth, Alena Savonenko, Christopher Gallardo, Dezhi Liao, Ana Covelo
المصدر: Acta Neuropathologica
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Parkinson's disease, Synucleinopathies, Tau protein, Hippocampus, Mice, Transgenic, tau Proteins, Biology, Neurotransmission, Lewy body disease, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, 0302 clinical medicine, Postsynaptic potential, Neuroplasticity, mental disorders, medicine, Animals, α-Synuclein, Neurons, Original Paper, Memory Disorders, Neuronal Plasticity, Dementia with Lewy bodies, medicine.disease, 3. Good health, Disease Models, Animal, 030104 developmental biology, Synapses, biology.protein, Parkinson’s disease, alpha-Synuclein, Dementia, Neurology (clinical), Tau, Neuroscience, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7782aededc54d3caa9d04e48ca50e0aTest
http://europepmc.org/articles/PMC6778173Test -
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المؤلفون: Mathew A. Sherman, Adriano Aguzzi, Megan Larson, Colleen L. Forster, David A. Bennett, Sylvain Lesné, Michael LaCroix, Martin Ramsden, Fatou Amar
المصدر: The Journal of Neuroscience. 36:9647-9658
مصطلحات موضوعية: Adult, 0301 basic medicine, Protein Conformation, Amyloid beta, Kinesins, Mice, Transgenic, tau Proteins, Axonal Transport, Amyloid beta-Protein Precursor, Mice, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, mental disorders, medicine, Animals, Humans, education, Cells, Cultured, Neurons, education.field_of_study, Amyloid beta-Peptides, biology, Chemistry, General Neuroscience, Neurodegeneration, Age Factors, Brain, Neurofibrillary Tangles, Neurofibrillary tangle, Articles, Human brain, Embryo, Mammalian, medicine.disease, Anterograde axonal transport, Cell biology, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, Kinesin light chain 1, Mutation, biology.protein, Axoplasmic transport, Microtubule-Associated Proteins, 030217 neurology & neurosurgery, Intracellular
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33855c5746459f4ecdbd6e76ac61e84Test
https://doi.org/10.1523/jneurosci.1899-16.2016Test -
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المؤلفون: Gabriel Boyle, Jacqeline Aldaco, Michael LaCroix, Fatou Amar, Mathew A. Sherman, George S. Bloom, Jennifer L. Brown, Shahzad S. Khan, Sylvain Lesné, Michael K. Lee
المصدر: Acta neuropathologica. 136(4)
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Protein Conformation, Primary Cell Culture, Mice, Transgenic, tau Proteins, Biology, Article, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Postsynaptic potential, Alzheimer Disease, Extracellular, medicine, Animals, Phosphorylation, Maze Learning, Alpha-synuclein, Mice, Knockout, Neurons, Lewy body, Excitatory Postsynaptic Potentials, Cell cycle, medicine.disease, Phenotype, Mice, Inbred C57BL, 030104 developmental biology, chemistry, alpha-Synuclein, Neurology (clinical), Neuron death, Neuroscience, 030217 neurology & neurosurgery, Gene Deletion
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8aac004b5ff4ecf711e81bf88a0cf4Test
https://pubmed.ncbi.nlm.nih.gov/29995210Test -
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المؤلفون: Sylvain Lesné, Angie C.A. Chiang, Stephanie W. Fowler, Rohit Reddy, Olga Pletnikova, Joanna L. Jankowsky, Juan C. Troncoso, Mathew A. Sherman
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Male, Transgene, Spatial Learning, Dot blot, Mice, Transgenic, Motor Activity, Article, Pathology and Forensic Medicine, 03 medical and health sciences, Mice, 0302 clinical medicine, Alzheimer Disease, medicine, Amyloid precursor protein, Animals, Humans, Cognitive decline, Aged, Spatial Memory, Aged, 80 and over, Amyloid beta-Peptides, biology, Chemistry, Amyloidosis, Brain, Middle Aged, medicine.disease, Cell biology, Blot, Disease Models, Animal, 030104 developmental biology, biology.protein, Female, Alzheimer's disease, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856fe4e6753f8f068d0434b3b75dfd4bTest
https://europepmc.org/articles/PMC5840490Test/ -
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المؤلفون: Sylvain Lesné, Gabriel Boyle, Alain Buisson, Megan Larson, Liu Chang, Fatou Amar, Mathew A. Sherman, Jürgen Götz, Travis Rush
المصدر: Science signaling. 10(478)
مصطلحات موضوعية: 0301 basic medicine, Male, Tau protein, Mice, Transgenic, tau Proteins, Biochemistry, Oligomer, Receptors, N-Methyl-D-Aspartate, Calcium in biology, 03 medical and health sciences, chemistry.chemical_compound, Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Alzheimer Disease, Ca2+/calmodulin-dependent protein kinase, medicine, Animals, Humans, Phosphorylation, Receptor, Molecular Biology, Cells, Cultured, Neurons, Amyloid beta-Peptides, biology, Brain, Cell Biology, medicine.disease, Cell biology, 030104 developmental biology, chemistry, biology.protein, Calcium, Female, Signal transduction, Alzheimer's disease, Protein Multimerization, Calcium-Calmodulin-Dependent Protein Kinase Type 2, 030217 neurology & neurosurgery, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3ef1f76cfa6d9083176b3e88f80969Test
https://pubmed.ncbi.nlm.nih.gov/35727863Test -
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المؤلفون: Dorothy R. Schuler, Mathew A. Sherman, Ricky R. Savjani, Stephanie W. Fowler, Megan Larson, Sylvain Lesné, John R. Cirrito, Joanna L. Jankowsky, Angie C.A. Chiang
المصدر: Journal of Neuroscience. 34:7871-7885
مصطلحات موضوعية: Amyloid, Morris water navigation task, Mice, Transgenic, Plaque, Amyloid, Water maze, Amyloid beta-Protein Precursor, Mice, Alzheimer Disease, Amyloid precursor protein, medicine, Animals, Humans, Cognitive decline, Maze Learning, Alanine, biology, Chemistry, General Neuroscience, P3 peptide, Articles, Azepines, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, Doxycycline, Mutation, Synapses, Exploratory Behavior, biology.protein, Amyloid Precursor Protein Secretases, Alzheimer's disease, Cognition Disorders, Neuroscience, Amyloid precursor protein secretase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2997839fbdee437e82f885d327b4c7e3Test
https://doi.org/10.1523/jneurosci.0572-14.2014Test -
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المؤلفون: Sylvain Lesné, Karen H. Ashe, Julie A. Schneider, Marianne K. O. Grant, Mathew A. Sherman, David A. Bennett, Michael A. Kuskowski
المصدر: Brain. 136:1383-1398
مصطلحات موضوعية: Adult, Male, Aging, medicine.medical_specialty, Pathology, Adolescent, Amyloid, Plaque, Amyloid, Cohort Studies, Pathogenesis, Young Adult, Cognition, FYN, Alzheimer Disease, Postsynaptic potential, Internal medicine, mental disorders, medicine, Humans, Child, Aged, Aged, 80 and over, Brain Chemistry, Amyloid beta-Peptides, Chemistry, Neurodegeneration, Infant, Original Articles, Middle Aged, medicine.disease, Cross-Sectional Studies, Endocrinology, Ageing, Child, Preschool, Female, Neurology (clinical), Protein Multimerization, Alzheimer's disease, Neuron death, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c147c0b301f2154a429d98bc81e702Test
https://doi.org/10.1093/brain/awt062Test -
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المؤلفون: Basavaraj Hooli, Roberto Malinow, Michael Leitges, Kristina Mullin, Corina E. Antal, Alexandra C. Newton, Mathew A. Sherman, Julia A. Callender, Sylvain Lesné, Stephanie Alfonso, Rudolph E. Tanzi
المصدر: Science signaling, vol 9, iss 427
مصطلحات موضوعية: 0301 basic medicine, Aging, Hippocampus, Neurodegenerative, Alzheimer's Disease, medicine.disease_cause, Biochemistry, Synapse, Mice, Neoplasms, Chlorocebus aethiops, 2.1 Biological and endogenous factors, Aetiology, Mutation, Genome, COS cells, Neurodegenerative Diseases, Cell biology, Neurological, COS Cells, Alzheimer's disease, Human, Protein Kinase C-alpha, PDZ domain, Biology, Article, 03 medical and health sciences, Protein Domains, Alzheimer Disease, Acquired Cognitive Impairment, Genetics, medicine, Animals, Humans, Protein kinase A, Molecular Biology, Protein kinase C, Family Health, Genome, Human, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Cell Biology, medicine.disease, Brain Disorders, 030104 developmental biology, Synapses, Dementia, Biochemistry and Cell Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12358b725c679c77ebbb2178a3b2af05Test
https://europepmc.org/articles/PMC5154619Test/ -
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المؤلفون: Adriano Aguzzi, Mathew A. Sherman, Mario Nuvolone, Fatou Amar, David A. Bennett, Julie A. Schneider, Sylvain Lesné, Megan Larson
المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(47)
مصطلحات موضوعية: Genetically modified mouse, Male, Dendritic spine, Immunoprecipitation, Blotting, Western, Gene Dosage, Mice, Transgenic, tau Proteins, Biology, Proto-Oncogene Proteins c-fyn, Article, PRNP, 03 medical and health sciences, Mice, 0302 clinical medicine, FYN, Alzheimer Disease, medicine, Animals, Humans, PrPC Proteins, Phosphorylation, Cells, Cultured, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, Amyloid beta-Peptides, Kinase, General Neuroscience, Neurofibrillary Tangles, medicine.disease, Molecular biology, Chromatography, Gel, Electrophoresis, Polyacrylamide Gel, Female, Alzheimer's disease, 030217 neurology & neurosurgery, Gene Deletion, Proto-oncogene tyrosine-protein kinase Src
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ade7e2984a0543a9c1382eaa2782bd4Test
https://pubmed.ncbi.nlm.nih.gov/23175838Test -
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المؤلفون: Michael A. Kuskowski, Julie A. Schneider, David A. Bennett, Sylvain Lesné, Susan Greimel, Mathew A. Sherman, Megan Larson
المصدر: J Neurosci
مصطلحات موضوعية: Genetically modified mouse, Transgene, Mice, Transgenic, tau Proteins, Neuropsychological Tests, Synaptic vesicle, Presenilin, Pathogenesis, chemistry.chemical_compound, Mice, Alzheimer Disease, medicine, Presenilin-1, Animals, Humans, Cognitive Dysfunction, Maze Learning, Aged, Alpha-synuclein, Aged, 80 and over, Neurons, Nerve Fibers, Unmyelinated, Amyloid beta-Peptides, Lewy body, General Neuroscience, medicine.disease, Temporal Lobe, Disease Models, Animal, chemistry, alpha-Synuclein, Alzheimer's disease, Erratum, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85247500f2e2856d63884b8e840c0688Test
https://pubmed.ncbi.nlm.nih.gov/35618413Test