نتائج البحث - "Maria Laura Belladonna"

1

Artocarpus tonkinensis Extract Inhibits LPS-Triggered Inflammation Markers and Suppresses RANKL-Induced Osteoclastogenesis in RAW264.7

المؤلفون: Giada Mondanelli, Sabrina Adorisio, Mario Calvitti, Trinh Thi Thuy, Claudia Volpi, Maria Laura Belladonna, Domenico Vittorio Delfino, Ciriana Orabona, Elena Orecchini

المصدر: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cc86b4ccdd27075fdf0c2b224e86b5Test
https://doi.org/10.3389/fphar.2020.593829Test

2

Kynurenine/Tryptophan Ratio as a Potential Blood-Based Biomarker in Non-Small Cell Lung Cancer

المؤلفون: Sara Baglivo, Francesca Romana Tofanetti, Jacopo Vannucci, Francesco Puma, Martina Mandarano, Angelo Sidoni, Rita Chiari, Elena Orecchini, Vienna Ludovini, Guido Bellezza, Elisabetta Loreti, Maria Laura Belladonna

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4403, p 4403 (2021)

مصطلحات موضوعية: Male, Lung Neoplasms, serum biomarkers, non-small cell lung cancer (NSCLC), indoleamine-2, B7-H1 Antigen, chemistry.chemical_compound, Carcinoma, Non-Small-Cell Lung, kynurenine/tryptophan (Kyn/Trp) ratio, Biology (General), Kynurenine, Spectroscopy, Aged, 80 and over, Tryptophan, General Medicine, Middle Aged, Prognosis, nonsmall cell lung cancer (NSCLC), Computer Science Applications, Survival Rate, Chemistry, medicine.anatomical_structure, indoleamine-2,3-dioxygenase 1 (IDO1), Carcinoma, Squamous Cell, Adenocarcinoma, Female, Adult, QH301-705.5, T cell, Adenocarcinoma of Lung, Article, Catalysis, Inorganic Chemistry, Lymphocytes, Tumor-Infiltrating, Immune system, 3-dioxygenase 1 (IDO1), Biomarkers, Tumor, medicine, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, immunohistochemical biomarkers, Physical and Theoretical Chemistry, Lung cancer, QD1-999, Molecular Biology, Aged, business.industry, Organic Chemistry, Cancer, medicine.disease, chemistry, Cancer research, Neoplasm Recurrence, Local, business, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7219228cb0e6b43e93b43a38f60c5f6bTest
http://hdl.handle.net/11391/1492548Test

3

Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation

المؤلفون: Maria Teresa Pallotta, Eleonora Panfili, Maria Laura Belladonna, Eva Tirelli, Giada Mondanelli, Carmine Vacca, Francesca Fallarino, Alberta Iacono, Elisa Proietti, Elena Orecchini, Paolo Prontera, Susanna Esposito, Ciriana Orabona, Marco Gargaro, Giulio Frontino, Ursula Grohmann, Paolo Puccetti

المصدر: Human Molecular Genetics

مصطلحات موضوعية: Proband, AcademicSubjects/SCI01140, endocrine system diseases, Wolfram syndrome, medicine.medical_treatment, Inflammation, Biology, medicine.disease_cause, Systemic inflammation, 03 medical and health sciences, Exon, 0302 clinical medicine, Genetics, medicine, Humans, Child, Molecular Biology, Genetics (clinical), 030304 developmental biology, Dominance (genetics), 0303 health sciences, Mutation, nutritional and metabolic diseases, Membrane Proteins, Wolfram Syndrome, General Medicine, Sequence Analysis, DNA, medicine.disease, Cytokine, Gene Expression Regulation, 030220 oncology & carcinogenesis, Immunology, Leukocytes, Mononuclear, Cytokines, Female, General Article, medicine.symptom

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0b316008de70e613afd7e6ec3223f8Test
https://pubmed.ncbi.nlm.nih.gov/33693650Test

4

Potential Benefits of Tryptophan Metabolism to the Efficacy of Tocilizumab in COVID-19

المؤلفون: Maria Laura Belladonna, Ciriana Orabona

المصدر: Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fce8e9f155fb92ad6b18a7a538a93dTest
https://www.frontiersin.org/article/10.3389/fphar.2020.00959/fullTest

5

Indoleamine 2,3-Dioxygenase 2 Immunohistochemical Expression in Resected Human Non-small Cell Lung Cancer: A Potential New Prognostic Tool

المؤلفون: Martina Mandarano, Guido Bellezza, Maria Laura Belladonna, Jacopo Vannucci, Alessio Gili, Ivana Ferri, Chiara Lupi, Vienna Ludovini, Giulia Falabella, Giulio Metro, Giada Mondanelli, Rita Chiari, Lucio Cagini, Fabrizio Stracci, Fausto Roila, Francesco Puma, Claudia Volpi, Angelo Sidoni

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, Adult, Male, 3-dioxygenase 2, 0301 basic medicine, Lung Neoplasms, Cell, Immunology, Adenocarcinoma, B7-H1 Antigen, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Biomarkers, Tumor, medicine, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Immunology and Allergy, Lung cancer, Indoleamine 2,3-dioxygenase, non-small cell lung cancer, Cellular localization, Original Research, Aged, Aged, 80 and over, business.industry, Cancer, immunomodulator, Middle Aged, Prognosis, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, immunohistochemistry, Carcinoma, Squamous Cell, Disease Progression, Cancer research, indoleamine 2, biomarker, Biomarker (medicine), Immunohistochemistry, Female, lcsh:RC581-607, business, Follow-Up Studies, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd359a51fa75ca167393e2703ce96a39Test

6

Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation

المساهمون: Gastroenterology & Hepatology, Mondanelli, G., Coletti, A., Greco, F. A., Pallotta, M. T., Orabona, C., Iacono, A., Belladonna, M. L., Albini, E., Panfili, E., Fallarino, F., Gargaro, M., Manni, G., Matino, D., Carvalho, A., Cunha, C., Maciel, P., Filippo, M. D., Gaetani, L., Bianchi, R., Vacca, C., Iamandii, I. M., Proietti, E., Boscia, F., Annunziato, L., Peppelenbosch, M., Puccetti, P., Calabresi, P., Macchiarulo, A., Santambrogio, L., Volpi, C., Grohmann, U.

المصدر: Proceedings of the National Academy of Sciences of the U.S.A., 117(7), 3848-3857. National Academy of Sciences
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Male, Kynurenine pathway, Metabolite, Pharmacology, Indoleamine 2,3-dioxygenase 1 (IDO1), Dendritic cells, chemistry.chemical_compound, 0302 clinical medicine, Neuroinflammation, Multiple Sclerosi, Indoleamine 2,3-dioxygenase, Kynurenine, Mice, Knockout, 0303 health sciences, Multidisciplinary, biology, Chemistry, Experimental autoimmune encephalomyelitis, Tryptophan, Biocatalysi, Biological Sciences, 3. Good health, Serotonin pathway, Settore MED/26 - NEUROLOGIA, Female, Dendritic cell, Allosteric Site, Human, Serotonin, Multiple Sclerosis, Allosteric modulator, Encephalomyelitis, Autoimmune, Experimental, 03 medical and health sciences, 3-dioxygenase 1 (IDO1), Allosteric Regulation, medicine, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, 030304 developmental biology, Aryl hydrocarbon receptor (AhR), N-acetylserotonin (NAS), Animal, medicine.disease, Aryl hydrocarbon receptor, Disease Models, Animal, Biocatalysis, biology.protein, Leukocytes, Mononuclear, 030217 neurology & neurosurgery, Indoleamine 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5e77a9c8cc1e47350ba4e58f154a1fTest
https://hdl.handle.net/11391/1458631Test

7

High PD-L1/IDO-2 and PD-L2/IDO-1 Co-Expression Levels Are Associated with Worse Overall Survival in Resected Non-Small Cell Lung Cancer Patients

المؤلفون: Guido Bellezza, Rita Chiari, Maria Laura Belladonna, Vincenzo Minotti, Giulio Metro, Francesca Romana Tofanetti, Fausto Roila, Maria Sole Reda, Martina Mandarano, Fortunato Bianconi, Sara Baglivo, Annamaria Siggillino, Valeria Berti, Francesco Puma, Vienna Ludovini, Angelo Sidoni, Jacopo Vannucci

المصدر: Genes
Volume 12
Issue 2
Genes, Vol 12, Iss 273, p 273 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, carcinoma, Gastroenterology, B7-H1 Antigen, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Gene expression, 80 and over, Stage (cooking), Genetics (clinical), Aged, 80 and over, Univariate analysis, biology, Hazard ratio, gene expression regulation, Middle Aged, Gene Expression Regulation, Neoplastic, Reverse transcription polymerase chain reaction, 030220 oncology & carcinogenesis, immune-related genes, dioxygenase, Female, Adult, tumor, medicine.medical_specialty, lcsh:QH426-470, mRNA expression levels, Disease-Free Survival, Article, 03 medical and health sciences, Internal medicine, PD-L1, Biomarkers, Tumor, Genetics, medicine, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Lung cancer, Aged, business.industry, biomarkers, Histology, early-stage NSCLC, prognostic markers, adult, aged, aged, 80 and over, B7-H1 antigen, biomarkers, tumor, carcinoma, non-small-cell lung, disease-free survival, female, gene expression regulation, neoplastic, humans, indoleamine-pyrrole 2,3,-dioxygenase, male, middle aged, programmed cell death 1 ligand 2 protein, Programmed Cell Death 1 Ligand 2 Protein, medicine.disease, neoplastic, indoleamine-pyrrole 2, lcsh:Genetics, non-small-cell lung, 030104 developmental biology, biology.protein, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf1f359e26fbb77adc2d91c3d80b10eTest
https://doi.org/10.3390/genes12020273Test

8

Assessment of TILs, IDO-1, and PD-L1 in resected non-small cell lung cancer: an immunohistochemical study with clinicopathological and prognostic implications

المؤلفون: Jacopo Vannucci, Lucio Cagini, Rachele Del Sordo, Vienna Ludovini, Martina Mandarano, Fortunato Bianconi, Giada Mondanelli, Giulio Metro, Ivana Ferri, Guido Bellezza, Angelo Sidoni, Elisa Albini, Francesco Puma, Benoît Van den Eynde, Maria Laura Belladonna, Rita Chiari

المساهمون: UCL - SSS/DDUV - Institut de Duve, UCL - SSS/DDUV/GECE - Génétique cellulaire

المصدر: Virchows Archiv, Vol. 474, no. 2, p. 159-168 (2019)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Lung Neoplasms, medicine.medical_treatment, Clone (cell biology), Kaplan-Meier Estimate, Tumor-infiltrating lymphocytes, B7-H1 Antigen, 0302 clinical medicine, Non-small cell lung cancer, Carcinoma, Non-Small-Cell Lung, Medicine, IDO-1, Aged, 80 and over, biology, General Medicine, Middle Aged, Prognosis, Immunohistochemistry, Immunosurveillance, Survival Rate, 030220 oncology & carcinogenesis, Adenocarcinoma, Female, Immunotherapy, PD-L1, medicine.medical_specialty, Disease-Free Survival, Pathology and Forensic Medicine, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, Internal medicine, Biomarkers, Tumor, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Lung cancer, Molecular Biology, Aged, business.industry, Cell Biology, medicine.disease, 030104 developmental biology, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d966d1f6f988e40e7aa05152f1db15Test
https://pubmed.ncbi.nlm.nih.gov/30448912Test

9

Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes

المساهمون: [et al.], Universidade do Minho

المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: 0301 basic medicine, endocrine system diseases, Autoimmunity, medicine.disease_cause, Immune tolerance, Mice, chemistry.chemical_compound, Mice, Inbred NOD, immune system diseases, Child, Indoleamine 2,3-dioxygenase, NOD mice, Diabetes, Tryptophan, General Medicine, 3. Good health, Amino acid metabolism, Immunology, Immunotherapy, Cytokines, Female, Research Article, endocrine system, Antibodies, Monoclonal, Humanized, Polymorphism, Single Nucleotide, Peripheral blood mononuclear cell, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, Tocilizumab, Diabetes mellitus, Immune Tolerance, medicine, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Genetic Association Studies, Type 1 diabetes, Science & Technology, business.industry, nutritional and metabolic diseases, medicine.disease, Receptors, Interleukin-6, Mice, Inbred C57BL, Disease Models, Animal, Diabetes Mellitus, Type 1, 030104 developmental biology, chemistry, Multivariate Analysis, Leukocytes, Mononuclear, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38d9bf9f6c79394a948a7575b7a9893Test
https://hdl.handle.net/1822/58064Test

10

Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells

المساهمون: Volpi, C, Mondanelli, G, Pallotta, M, Vacca, C, Iacono, A, Gargaro, M, Albini, E, Bianchi, R, Belladonna, M, Celanire, S, Mordant, C, Heroux, M, Royer Urios, I, Schneider, M, Vitte, P, Cacquevel, M, Galibert, L, Poli, S, Solari, A, Bicciato, S, Calvitti, M, Antognelli, C, Puccetti, P, Orabona, C, Fallarino, F, Grohmann, U

المصدر: Neuropharmacology

مصطلحات موضوعية: 0301 basic medicine, Autoimmunity, Receptors, Metabotropic Glutamate, PI3K, phosphatidylinositol-3-kinase, Dendritic cells, PI3K, Immune regulation, Indoleamine 2 3-dioxygenase 1, mGluR4, Neuroinflammation, Noncanonical GPCR signaling, Src kinase, Tryptophan metabolism, Cellular and Molecular Neuroscience, Pharmacology, Mice, Phosphatidylinositol 3-Kinases, RNA, Small Interfering, Metabotropic glutamate receptor 4, Experimental autoimmune encephalomyelitis, DC, Dendritic cell, 3. Good health, Cell biology, PAM, positive allosteric modulator, Treg, T regulatory, IDO1, indoleamine 2,3-dioxygenase 1, Female, Signal transduction, Dendritic cell, Signal Transduction, Allosteric modulator, Allosteric regulation, Indoleamine 2,3-dioxygenase 1, Biology, Pertussis toxin, Article, 03 medical and health sciences, Allosteric Regulation, RR-EAE, relapsing-remitting experimental autoimmune encephalomyelitis, mGluR, metabotropic glutamate receptor, medicine, Animals, Indoleamine-Pyrrole 2,3,-Dioxygenase, PI3K/AKT/mTOR pathway, ITIM, immunoreceptor tyrosine-based inhibitory motif, medicine.disease, Thiazoles, 3-dioxygenase 1, Pyrimidines, 030104 developmental biology, Immunology, Cytokine secretion, Indoleamine 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e92821c130279fa59a9d3c6295d4adTest
http://hdl.handle.net/11391/1361142Test

تنقيح النتائج