نتائج البحث - "Agostina Nardone"

1

Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer

المساهمون: De Angelis, C., Fu, X., Cataldo, M. L., Nardone, A., Pereira, R., Veeraraghavan, J., Nanda, S., Qin, L., Sethunath, V., Wang, T., Hilsenbeck, S. G., Benelli, M., Migliaccio, I., Guarducci, C., Malorni, L., Litchfield, L. M., Liu, J., Donaldson, J., Selenica, P., Brown, D. N., Weigelt, B., Reis-Filho, J. S., Park, B. H., Hurvitz, S. A., Slamon, D. J., Rimawi, M. F., Jansen, V. M., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 17

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pyridines, Oncology and Carcinogenesis, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Palbociclib, Piperazines, 03 medical and health sciences, 0302 clinical medicine, Immune system, Breast cancer, Receptors, Breast Cancer, Genetics, Tumor Cells, Cultured, Humans, Medicine, Oncology & Carcinogenesis, Cancer, Cultured, biology, business.industry, Kinase, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, medicine.disease, Estrogen, Immune checkpoint, Tumor Cells, Good Health and Well Being, 030104 developmental biology, Receptors, Estrogen, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Cyclin-dependent kinase 6, Development of treatments and therapeutic interventions, Signal transduction, business, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8d5dea84c01cc54303c5f5ebf7c4dcTest
https://doi.org/10.1158/1078-0432.ccr-19-4191Test

2

FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer

المساهمون: Fu, X., Pereira, R., De Angelis, C., Veeraraghavan, J., Nanda, S., Qin, L., Cataldo, M. L., Sethunath, V., Mehravaran, S., Gutierrez, C., Chamness, G. C., Feng, Q., O'Malley, B. W., Selenica, P., Weigelt, B., Reis-Filho, J. S., Cohen, O., Wagle, N., Nardone, A., Jeselsohn, R., Brown, M., Rimawi, M. F., Osborne, C. K., Schiff, R.

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Multidisciplinary, Chromatin binding, Pioneer factor, Enhancer/transcriptional reprogramming, Biological Sciences, Biology, medicine.disease, Metastatic breast cancer, Metastasis, Breast cancer, Cancer research, medicine, FOXA1, Transcription factor, Reprogramming, Endocrine resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524cedf1e32bed7312ca09dcdb1188ecTest
https://doi.org/10.1073/pnas.1911584116Test

3

The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance

المؤلفون: Agostina Nardone, Rachel Schiff, Henry Brown, Meghana V. Trivedi, Martin Shea, Mark Pilling, Jamunarani Veeraraghavan, Chandandeep Nagi, Rinath Jeselsohn, Carmine De Angelis, Oona Delpuech, Maria Letizia Cataldo, Tamika Mitchell, C. Kent Osborne, Mothaffar F. Rimawi, Hazel M. Weir, Gary C. Chamness, Xiaoyong Fu, Susan G. Hilsenbeck

المساهمون: Pilling, Mark [0000-0002-7446-6597], Apollo - University of Cambridge Repository, Nardone, A., Weir, H., Delpuech, O., Brown, H., De Angelis, C., Cataldo, M. L., Fu, X., Shea, M. J., Mitchell, T., Veeraraghavan, J., Nagi, C., Pilling, M., Rimawi, M. F., Trivedi, M., Hilsenbeck, S. G., Chamness, G. C., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Indoles, Neoplasms, Hormone-Dependent, Breast Neoplasms, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, MCF-7 Cell, 0302 clinical medicine, Breast cancer, Cinnamate, In vivo, medicine, Animals, Humans, Receptor, skin and connective tissue diseases, Fulvestrant, Cancer, Cell Proliferation, Estradiol, Animal, Cell growth, Estrogens, medicine.disease, Estrogen, Metastatic breast cancer, 3. Good health, Tamoxifen, Oncology, chemistry, Receptors, Estrogen, Indole, Cell culture, Cinnamates, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, MCF-7 Cells, Heterografts, Female, Growth inhibition, Heterograft, Breast Neoplasm, Human, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1307add3c66d5075ec69b579adb4aedTest
http://europepmc.org/articles/PMC6353941Test

4

A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer

المساهمون: Thangavel, Hariprasad, De Angelis, Carmine, Vasaikar, Suha, Bhat, Raksha, Jolly, Mohit Kumar, Nagi, Chandandeep, Creighton, Chad J, Chen, Fengju, Dobrolecki, Lacey E, George, Jason T, Kumar, Tanya, Abdulkareem, Noor Mazin, Mao, Sufeng, Nardone, Agostina, Rimawi, Mothaffar, Osborne, C Kent, Lewis, Michael T, Levine, Herbert, Zhang, Bing, Schiff, Rachel, Giuliano, Mario, Trivedi, Meghana V

المصدر: Journal of Clinical Medicine
Volume 8
Issue 11
Journal of Clinical Medicine, Vol 8, Iss 11, p 1772 (2019)

مصطلحات موضوعية: False discovery rate, RPPA, patient-derived xenograft, lcsh:Medicine, circulating tumor cells, circulating tumor cell, Article, Transcriptome, CTC cluster, 03 medical and health sciences, transcriptomics, 0302 clinical medicine, Circulating tumor cell, Breast cancer, Centre for Biosystems Science and Engineering, medicine, B-cell lymphoma 2, Triple-negative breast cancer, 030304 developmental biology, 0303 health sciences, business.industry, lcsh:R, apoptosis, General Medicine, transcriptomic, Gene signature, medicine.disease, apoptosi, 3. Good health, Lymphoma, 030220 oncology & carcinogenesis, Cancer research, triple-negative breast cancer, Immunohistochemistry, CTC clusters, business

وصف الملف: application/pdf; application/zip

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79d31cd7705c3a50e6d75fb9541f82dTest

5

Abstract PD8-03: A FOXA1/FRA1-centered transcriptional axis regulates interferon signaling in high FOXA1-associated endocrine-resistant and metastatic breast cancer

المؤلفون: Rinath Jeselsohn, Carmine De Angelis, Rachel Schiff, Mothaffar F. Rimawi, Sarmistha Nanda, Resel Pereira, Xiaoyong Fu, Agostina Nardone, Martin Shea, Lanfang Qin, Nikhil Wagle, Ofir Cohen, C. Kent Osborne

المصدر: Cancer Research. 81:PD8-03

مصطلحات موضوعية: Cancer Research, Oncology, business.industry, Interferon, Cancer research, Medicine, Endocrine system, FOXA1, business, medicine.disease, Metastatic breast cancer, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e5d2f0da284154e69eed6ec36611de8dTest
https://doi.org/10.1158/1538-7445.sabcs20-pd8-03Test

6

Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis

المؤلفون: Chandandeep Nagi, Hariprasad Thangavel, Mario Giuliano, Lacey E. Dobrolecki, Agostina Nardone, Carmine De Angelis, Meghana V. Trivedi, Michael T. Lewis, Rachel Schiff, Jackie L. Stilwell, C. Kent Osborne, Debashish Sahay, Sina Hedayatpour, Raksha Bhat, Eric P. Kaldjian, Mothaffar F. Rimawi, Arturo Ramirez

المساهمون: Ramirez, A. B., Bhat, R., Sahay, D., De Angelis, C., Thangavel, H., Hedayatpour, S., Dobrolecki, L. E., Nardone, A., Giuliano, M., KHALIL RODRIGUEZ, Nagi, Rimawi, M., Osborne, C. K., Lewis, M. T., Stilwell, J. L., Kaldjian, E. P., Schiff, R., Trivedi, M. V.

المصدر: BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cell Separation, Mice, SCID, Metastasis, Antineoplastic Agent, Mice, 0302 clinical medicine, Circulating tumor cell, Breast cancer, Single-cell analysis, Class I Phosphatidylinositol 3-Kinase, medicine.diagnostic_test, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Neoplastic Cells, Circulating, 3. Good health, Patient-derived xenografts, Oncology, 030220 oncology & carcinogenesis, Single-cell analysi, Immunohistochemistry, Keratins, Female, Single-Cell Analysis, Breast Neoplasm, Research Article, Human, Class I Phosphatidylinositol 3-Kinases, Antineoplastic Agents, Breast Neoplasms, Immunofluorescence, lcsh:RC254-282, 03 medical and health sciences, Patient-derived xenograft, Cell Line, Tumor, Genetics, medicine, Biomarkers, Tumor, Animals, Humans, Chemotherapy, Cluster of differentiation, business.industry, Animal, Circulating tumor cells, Leukocyte Common Antigen, Sequence Analysis, DNA, medicine.disease, 030104 developmental biology, Keratin, Cancer cell, Mutation, Cancer research, Leukocyte Common Antigens, business, Neoplasm Transplantation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688296ce56fe9a1f54200af1da1bcffeTest
http://hdl.handle.net/11588/771300Test

7

The changing role of ER in endocrine resistance

المؤلفون: Agostina Nardone, Carmine De Angelis, Meghana V. Trivedi, C. Kent Osborne, Rachel Schiff

المساهمون: Nardone, A., De Angelis, C., Trivedi, M. V., Osborne, C. K., Schiff, R.

المصدر: The Breast. 24:S60-S66

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b3567fe1a4024b41f0048bda524accTest
https://doi.org/10.1016/j.breast.2015.07.015Test

8

Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy

المساهمون: Giuliano, Mario, Hu, H, Wang, Yc, Fu, X, Nardone, Agostina, Herrera, S, Mao, S, Contreras, A, Gutierrez, C, Wang, T, Hilsenbeck, Sg, DE ANGELIS, Carmine, Wang, Nj, Heiser, Lm, Gray, Jw, Lopez Tarruella, S, Pavlick, Ac, Trivedi, Mv, Chamness, Gc, Chang, Jc, Osborne, Ck, Rimawi, Mf, Schiff, R.

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Time Factors, Antineoplastic Agents, Hormonal, Cell Survival, Receptor, ErbB-2, medicine.medical_treatment, Gene Expression, Estrogen receptor, Breast Neoplasms, Lapatinib, Article, Mice, Downregulation and upregulation, Cell Line, Tumor, Internal medicine, Animals, Humans, Medicine, Molecular Targeted Therapy, Epidermal growth factor receptor, skin and connective tissue diseases, neoplasms, Neoadjuvant therapy, biology, Fulvestrant, business.industry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Neoadjuvant Therapy, Disease Models, Animal, Endocrinology, Proto-Oncogene Proteins c-bcl-2, Receptors, Estrogen, Oncology, Drug Resistance, Neoplasm, Tumor progression, Quinazolines, Cancer research, biology.protein, Female, Receptors, Progesterone, business, Biomarkers, Signal Transduction, medicine.drug