المؤلفون: Jagadeesh Aluri, Bhaskar Rege, Margaret Moline, Takashi Yoshinaga, Borje Darpo, Sanae Yasuda, Meijian Zhou, Jim Ferry, Kenya Nakai, Nancy Hall, Patricia Murphy

المصدر: The Journal of Clinical Pharmacology. 57:96-104

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, animal structures, Long QT syndrome, Cmax, Lemborexant, 030204 cardiovascular system & hematology, Pharmacology, Placebo, Models, Biological, 030226 pharmacology & pharmacy, QT interval, Electrocardiography, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Pharmacokinetics, Risk Factors, Internal medicine, Drug Discovery, medicine, Humans, Pharmacology (medical), Dose-Response Relationship, Drug, medicine.diagnostic_test, Concentration Response, business.industry, Middle Aged, medicine.disease, Long QT Syndrome, Cardiology, Female, Orexin Receptor Antagonists, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f375ca17f93af078821ce32248c04d14Test
https://doi.org/10.1002/jcph.785Test

المؤلفون: Kenya Nakai, Kenji Kosaka, Masaki Nakagawa, Manabu Ikeda, Hideaki Miyagishi, Etsuro Mori

المصدر: Journal of the Neurological Sciences. 366:184-190

مصطلحات موضوعية: Male, Dementia with Lewy bodies, Blood Pressure, Neuropsychological Tests, Severity of Illness Index, law.invention, Cognition, 0302 clinical medicine, Piperidines, Randomized controlled trial, law, Cognitive/behavioral, Donepezil, 030212 general & internal medicine, Nootropic Agents, Aged, 80 and over, Dementia/aging, medicine.diagnostic_test, Parkinsonism, Middle Aged, Treatment Outcome, Cytochrome P-450 CYP2D6, Neurology, Indans, Mini-Mental State Examination, Female, Safety, Psychology, Clinical psychology, medicine.drug, Lewy Body Disease, medicine.medical_specialty, Efficacy, Clinical Neurology, Urology, Clinical, 03 medical and health sciences, Rating scale, mental disorders, medicine, Humans, Pharmacokinetis, Pulse, Aged, Mini–Mental State Examination, Dose-Response Relationship, Drug, Body Weight, medicine.disease, Blood pressure, Neurology (clinical), Mental Status Schedule, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dbd06e8fa6d0f6b9a275bc13964c23Test
https://doi.org/10.1016/j.jns.2016.05.001Test

المؤلفون: Kenya Nakai, Keiichi Kubota, Hiromitsu Kumada, Yasuo Ohno, Seiichi Ishida, Momoko Sunouchi, Junji Kita, Wataru Habano, Fumitaka Suzuki, Hiroyasu Ogata, Hiromasa Tanaka, Shogo Ozawa, Atsuko Miyajima, Kazuhiko Hanada, Yuichiro Kamikawa

المصدر: Drug Metabolism and Disposition. 36:1786-1793

مصطلحات موضوعية: Liver Cirrhosis, medicine.medical_specialty, Organic Cation Transport Proteins, Organic Anion Transporters, Sodium-Dependent, Pharmaceutical Science, Polymerase Chain Reaction, Proinflammatory cytokine, Cytochrome P-450 Enzyme System, Internal medicine, medicine, Humans, RNA, Messenger, Interleukin 6, Pharmacology, Organic cation transport proteins, Symporters, biology, medicine.diagnostic_test, Transporter, Hepatitis C, Chronic, Molecular biology, Isoenzymes, Endocrinology, Liver biopsy, Disease Progression, biology.protein, Tumor necrosis factor alpha, Drug metabolism, Organic anion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55aa95b8c9ca0f91de27c06cecf96866Test
https://doi.org/10.1124/dmd.107.020073Test

المؤلفون: Hiromitsu Kumada, Shogo Ozawa, Fumitaka Suzuki, Hiromasa Tanaka, Yasuo Ohno, Kazuhiko Hanada, Kenya Nakai, Hiroyasu Ogata

المصدر: Drug metabolism and pharmacokinetics. 27(3)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Receptors, Steroid, ATP Binding Cassette Transporter, Subfamily B, Biopsy, Pharmaceutical Science, Down-Regulation, Organic Anion Transporters, Sodium-Dependent, Receptors, Cytoplasmic and Nuclear, Biology, Downregulation and upregulation, Cytochrome P-450 Enzyme System, Fibrosis, Internal medicine, medicine, Basic Helix-Loop-Helix Transcription Factors, Humans, Pharmacology (medical), RNA, Messenger, Glucuronosyltransferase, Constitutive Androstane Receptor, Pharmacology, Cell Nucleus, Pregnane X receptor, medicine.diagnostic_test, Symporters, Multidrug resistance-associated protein 2, Organic Cation Transporter 1, Pregnane X Receptor, Hepatitis C, Hepatitis C, Chronic, Middle Aged, medicine.disease, Endocrinology, Nuclear receptor, Gene Expression Regulation, Liver, Receptors, Aryl Hydrocarbon, Liver biopsy, Disease Progression, Female, Signal transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7ba363a0f34cf7a1fe5c1244f65f97Test
https://pubmed.ncbi.nlm.nih.gov/22166890Test