نتائج البحث - "David J. Brooks"

1

Reduced Synaptic Density in Patients with Lewy Body Dementia: An [ 11 C ] UCB‐J PET Imaging Study

المؤلفون: Erik H. Danielsen, Per Borghammer, Malene Flensborg Damholdt, Casper Skjærbæk, Jacob Horsager, David J. Brooks, Anna C. Schacht, Hanne Gottrup, Allan K Hansen, Henriette Klit, Katrine B. Andersen

المصدر: Andersen, K B, Hansen, A K, Damholdt, M F, Horsager, J, Skjaerbaek, C, Gottrup, H, Klit, H, Schacht, A C, Danielsen, E H, Brooks, D J & Borghammer, P 2021, ' Reduced Synaptic Density in Patients with Lewy Body Dementia : An [ 11 C-]UCB-J PET Imaging Study ', Movement Disorders, vol. 36, no. 9, pp. 2057-2065 . https://doi.org/10.1002/mds.28617Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9750704b9dbf19797286345c50f195d4Test
https://doi.org/10.1002/mds.28617Test

2

Activated N-methyl-D-aspartate receptor ion channels detected in focal epilepsy with [18F]GE-179 positron emission tomography

المؤلفون: Martin J. Dietz, Dirk Bender, Ali Khalidan Vibholm, David J. Brooks, Arne Møller, Jan Jacobsen, Andreas Højlund, Sándor Beniczky, Jakob Christensen

المصدر: Vibholm, A K, Dietz, M J, Beniczky, S, Christensen, J, Højlund, A, Jacobsen, J, Bender, D, Møller, A & Brooks, D J 2021, ' Activated N-methyl-D-aspartate receptor ion channels detected in focal epilepsy with [ 18 F]GE-179 positron emission tomography ', Epilepsia, vol. 62, no. 12, pp. 2899-2908 . https://doi.org/10.1111/epi.17074Test

مصطلحات موضوعية: medicine.diagnostic_test, Chemistry, PET imaging, Standardized uptake value, Electroencephalography, medicine.disease, Statistical parametric mapping, Epilepsy, Nuclear magnetic resonance, Neurology, Positron emission tomography, Radioligand, medicine, NMDA ion channel, NMDA receptor, epilepsy, Ictal, Neurology (clinical)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54686a9473d01c111b0969f387b0ce87Test
https://pure.au.dk/portal/da/publications/activated-nmethyldaspartate-receptor-ion-channels-detected-in-focal-epilepsy-with-18fge179-positron-emission-tomographyTest(4da44a76-ff0e-4b43-864c-bb1dd0508357).html

3

Preclinical PET Studies of [11C]UCB-J Binding in Minipig Brain

المؤلفون: Anne M. Landau, Majken B. Thomsen, Heidi Kaastrup Müller, Jan Jacobsen, Dariusz Orlowski, Aage Kristian Olsen Alstrup, Thea P. Lillethorup, Simone L. Baerentzen, Ove Noer, Betina Elfving, Anna C. Schacht, David J. Brooks

المصدر: Thomsen, M B, Schacht, A C, Alstrup, A K O, Jacobsen, J, Lillethorup, T P, Bærentzen, S L, Noer, O, Orlowski, D, Elfving, B, Müller, H K, Brooks, D J & Landau, A M 2020, ' Preclinical PET Studies of [ 11 C]UCB-J Binding in Minipig Brain ', Molecular Imaging and Biology, vol. 22, no. 5, pp. 1290-1300 . https://doi.org/10.1007/s11307-020-01506-8Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4692ef3bc0973db1969e21b8c07830caTest
https://doi.org/10.1007/s11307-020-01506-8Test

4

A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies

المساهمون: Radiology and nuclear medicine, Amsterdam Neuroscience - Brain Imaging, ACS - Heart failure & arrhythmias, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Chalon, Sylvie, VU University Medical Center [Amsterdam], Univ Groningen, Univ Med Ctr Groningen, Lund University [Lund], Perani, D, Iaccarino, L, Lammertsma, Aa, Windhorst, Ad, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A, on behalf of all partners of the IMBI, Project, Lammertsma, A, Windhorst, A, Bottlaender, M, Brooks, D, Carroll, M, Chalon, S, Gee, A, Gerhard, A, Halldin, C, Herholz, K, Herth, M, Hinz, R, Knudsen, G, Kuhnast, B, Lopez-Picon, F, Moresco, R, Pappata, S, Rinne, J, Rodriguez-Vieitez, E, Santiago-Ribeiro, M, Turkheimer, F, Van Laere, K, Varrone, A, Vercouillie, J, Winkeler, A

المصدر: Perani, D, Iaccarino, L, Lammertsma, A A, Windhorst, A D, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A H & IMBI Project 2019, ' A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies ', Alzheimer's and Dementia, vol. 15, no. 8, pp. 1081-1103 . https://doi.org/10.1016Test/j.jalz.2019.02.004
Alzheimer's and Dementia, 15(8), 1081-1103. Elsevier
Perani, D, Iaccarino, L, Lammertsma, A A, Windhorst, A D, Edison, P, Boellaard, R, Hansson, O, Nordberg, A, Jacobs, A H & Partners IMBI Project 2019, ' A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies ', Alzheimer's & Dementia, vol. 15, no. 8, pp. 1081-1103 . https://doi.org/10.1016Test/j.jalz.2019.02.004
Alzheimers & dementia, 15(8), 1081-1103. ELSEVIER SCIENCE INC
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Wiley, 2019, 15 (8), pp.1081-1103. ⟨10.1016/j.jalz.2019.02.004⟩

مصطلحات موضوعية: 0301 basic medicine, 18-KDA TRANSLOCATOR PROTEIN, MILD COGNITIVE IMPAIRMENT, Epidemiology, PET TRACER F-18-AV-1451, [SDV]Life Sciences [q-bio], Diagnostic tools, Abnormal protein, AMYOTROPHIC-LATERAL-SCLEROSIS, chemistry.chemical_compound, 0302 clinical medicine, Neuroinflammation, Medicine, TAU-PET, ComputingMilieux_MISCELLANEOUS, IN-VIVO, medicine.diagnostic_test, Health Policy, Amyloid, Neuroinflammation, PET molecular imaging, Protheinopathies, Radiotracers, Tau, Neurodegenerative Diseases, Frontotemporal lobar degeneration, ALZHEIMERS ASSOCIATION WORKGROUPS, 3. Good health, [SDV] Life Sciences [q-bio], Psychiatry and Mental health, Radiotracers, Positron emission tomography, Protheinopathie, Specific protein, Amyloid, PET molecular imaging, Neuroimaging, Neuropathology, CEREBRAL AMYLOID ANGIOPATHY, 03 medical and health sciences, Cellular and Molecular Neuroscience, Developmental Neuroscience, Humans, Proteostasis Deficiencies, FRONTOTEMPORAL LOBAR DEGENERATION, Radiotracer, business.industry, PITTSBURGH COMPOUND-B, medicine.disease, 030104 developmental biology, chemistry, Positron-Emission Tomography, Protheinopathies, Neurology (clinical), Geriatrics and Gerontology, Molecular imaging, Tau, business, Pittsburgh compound B, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5303c97f26d0a4c4daf3ecbe61eb94fTest
https://research.rug.nl/en/publications/31d7324a-6cc7-43e1-8d81-b70469a0330aTest

5

Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter

المؤلفون: David J. Brooks, Richard Nicholas, Sujata Sridharan, Paolo A. Muraro, David R. Owen, Roger N. Gunn, Chris Record, Ashwini Nandoskar, David J. Sharp, Joel Raffel

المساهمون: Medical Research Council (MRC), Imperial College Healthcare NHS Trust- BRC Funding, Alzheimer's Research UK (ARUK), National Institute for Health Research

المصدر: Sridharan, S, Raffel, J, Nandoskar, A, Record, C, Brooks, D, Owen, D, Sharp, D, Muraro, P, Gunn, R & Nicholas, R 2019, ' Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [ 18 F]GE-180 : a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter ', Multiple Sclerosis Journal, vol. 21, no. 5, pp. 935-944 . https://doi.org/10.1007/s11307-019-01323-8Test

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1357100ca4d9a95a191965559dd24a8Test
https://doi.org/10.1007/s11307-019-01323-8Test

6

Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease

المؤلفون: Tatyana D. Fedorova, Christopher E J Doppler, Allan K Hansen, Corinna Brune, Gereon R. Fink, Per Borghammer, David J. Brooks, Martin B. Kinnerup, Michael Sommerauer, Karoline Knudsen, Rola Ismail, Matthew J. Betts, Kristian Stær, Adjmal Nahimi, Aline D. Seger, Jeppe L. Schaldemose, Ezequiel Farrher

المصدر: Brain 144(9), 2732-2744 (2021). doi:10.1093/brain/awab236
Brain 144(9), 2732–2744 (2021). doi:10.1093/brain/awab236
Doppler, C E J, Kinnerup, M B, Brune, C, Farrher, E, Betts, M, Fedorova, T D, Schaldemose, J L, Knudsen, K, Ismail, R, Seger, A D, Hansen, A K, Stær, K, Fink, G R, Brooks, D J, Nahimi, A, Borghammer, P & Sommerauer, M 2021, ' Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease ', Brain : a journal of neurology, vol. 144, no. 9, pp. 2732–2744 . https://doi.org/10.1093/brain/awab236Test
Brain

مصطلحات موضوعية: Male, Parkinson's disease, positron emission tomography, Multimodal Imaging, 0302 clinical medicine, methods [Magnetic Resonance Imaging], SLC6A2 protein, human, diagnostic imaging [Parkinson Disease], Aged, 80 and over, 0303 health sciences, medicine.diagnostic_test, AcademicSubjects/SCI01870, musculoskeletal, neural, and ocular physiology, Neurodegeneration, methods [Positron-Emission Tomography], Parkinson Disease, Middle Aged, Magnetic Resonance Imaging, humanities, Locus Coeruleus, Female, neuromelanin, diagnostic imaging [Locus Coeruleus], psychological phenomena and processes, medicine.drug, metabolism [Norepinephrine Plasma Membrane Transport Proteins], MeNER, medicine.medical_specialty, endocrine system, metabolism [Parkinson Disease], Locus (genetics), metabolism [Locus Coeruleus], 03 medical and health sciences, Norepinephrine, Neuromelanin, Internal medicine, medicine, Humans, ddc:610, 030304 developmental biology, Aged, Norepinephrine Plasma Membrane Transport Proteins, business.industry, methods [Multimodal Imaging], Locus Ceruleus, Magnetic resonance imaging, Scientific Commentaries, medicine.disease, Endocrinology, nervous system, Positron-Emission Tomography, Parkinson’s disease, noradrenaline, Locus coeruleus, AcademicSubjects/MED00310, Neurology (clinical), business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b6960feec5575c27399353d2becfefTest
https://pub.dzne.de/record/163310Test

7

Brain-first versus body-first Parkinson's disease:a multimodal imaging case-control study

المصدر: Horsager, J, Andersen, K B, Knudsen, K, Skjærbæk, C, Fedorova, T D, Okkels, N, Schaeffer, E, Bonkat, S K, Geday, J, Otto, M, Sommerauer, M, Danielsen, E H, Bech, E, Kraft, J, Munk, O L, Hansen, S D, Pavese, N, Göder, R, Brooks, D J, Berg, D & Borghammer, P 2020, ' Brain-first versus body-first Parkinson's disease : a multimodal imaging case-control study ', Brain, vol. 143, no. 10, pp. 3077-3088 . https://doi.org/10.1093/brain/awaa238Test

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa359da95faa9945a417fc561d83004Test
https://pure.au.dk/portal/da/publications/brainfirst-versus-bodyfirst-parkinsons-diseaseTest(ea00fe37-afa2-4c66-ae5c-00e64af0b30b).html

8

Preserved noradrenergic function in Parkinson's disease patients with rest tremor

المؤلفون: Michael Sommerauer, Karoline Knudsen, David J. Brooks, Allan K Hansen, Kristian Stær, Adjmal Nahimi, Tatyana D. Fedorova, Jeppe L. Schaldemose, Martin B. Kinnerup, Per Borghammer, Astrid Juhl Terkelsen, Malene Flensborg Damholdt, Rola Ismail, Nicola Pavese, Casper Skjærbæk

المصدر: Kinnerup, M B, Sommerauer, M, Damholdt, M F, Schaldemose, J L, Ismail, R, Terkelsen, A J, Stær, K, Hansen, A, Fedorova, T D, Knudsen, K, Skjærbæk, C, Borghammer, P, Pavese, N, Brooks, D J & Nahimi, A 2021, ' Preserved noradrenergic function in Parkinson's disease patients with rest tremor ', Neurobiology of Disease, vol. 152, 105295 . https://doi.org/10.1016Test/j.nbd.2021.105295
Neurobiology of Disease, Vol 152, Iss, Pp 105295-(2021)

مصطلحات موضوعية: 0301 basic medicine, Noradrenergic neurons, Adrenergic Neurons, Male, medicine.medical_specialty, Parkinson's disease, Red nucleus, Thalamus, Urology, Presynaptic Terminals, Rest tremor, lcsh:RC321-571, 03 medical and health sciences, Reboxetine, 0302 clinical medicine, Dorsal raphe nucleus, Tremor, medicine, Humans, C-MeNER, Carbon Radioisotopes, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Aged, Noradrenaline transporter, medicine.diagnostic_test, business.industry, Brain, Parkinson Disease, Middle Aged, medicine.disease, eye diseases, 11C-MeNER, 030104 developmental biology, Cross-Sectional Studies, Neurology, Positron emission tomography, Positron emission tomography (PET), Positron-Emission Tomography, Locus coeruleus, Female, Radiopharmaceuticals, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0949b00d6036ab7ca07a4170dcd22ef8Test
https://pubmed.ncbi.nlm.nih.gov/33549722Test

9

EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0

المساهمون: Radiology and Nuclear Medicine, Radiology and nuclear medicine, Amsterdam Neuroscience - Brain Imaging, Amsterdam Movement Sciences, AMS - Tissue Function & Regeneration

المصدر: European journal of nuclear medicine and molecular imaging 47(8), 1885-1912 (2020). doi:10.1007/s00259-020-04817-8
Morbelli, S, Esposito, G, Arbizu, J, Barthel, H, Boellaard, R, Bohnen, N I, Brooks, D J, Darcourt, J, Dickson, J C, Douglas, D, Drzezga, A, Dubroff, J, Ekmekcioglu, O, Garibotto, V, Herscovitch, P, Kuo, P, Lammertsma, A, Pappata, S, Peñuelas, I, Seibyl, J, Semah, F, Tossici-Bolt, L, Van de Giessen, E, Van Laere, K, Varrone, A, Wanner, M, Zubal, G & Law, I 2020, ' EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0 ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 47, no. 8, pp. 1885-1912 . https://doi.org/10.1007/s00259-020-04817-8Test
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 47, No 8 (2020) pp. 1885-1912
Morbelli, S, Esposito, G, Arbizu, J, Barthel, H, Boellaard, R, Bohnen, N, Brooks, D J, Darcourt, J, Dickson, J C, Douglas, D, Drzezga, A, Dubroff, J, Ekmekcioglu, O, Garibotto, V, Herscovitch, P, Kuo, P, Lammertsma, A, Pappata, S, Penuelas, I, Seibyl, J, Semah, F, Tossici-Bolt, L, Van de Giessen, E, Van Laere, K, Varrone, A, Wanner, M, Zubal, G & Law, I 2020, ' EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0 ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 47, no. 8, pp. 1885-1912 . https://doi.org/10.1007/s00259-020-04817-8Test
European journal of nuclear medicine and molecular imaging, 47(8), 1885-1912. Springer Verlag
European Journal of Nuclear Medicine and Molecular Imaging, 47(8), 1885-1912. Springer Verlag
European Journal of Nuclear Medicine and Molecular Imaging

مصطلحات موضوعية: medicine.medical_specialty, I-123-IOFLUPANE SPECT IMAGES, HEALTHY CONTROLS, Guidelines, Single-photon emission computed tomography, ddc:616.0757, Parkinsonian syndromes, POSITRON-EMISSION-TOMOGRAPHY, I-123-FP-CIT SPECT, Brain, DAT, DOPA, Parkinson, PET, SPECT, Parkinsonian Disorders, Spect imaging, medicine, Humans, Radiology, Nuclear Medicine and imaging, Medical physics, Fluorodopa, ddc:610, Radionuclide Imaging, Dopamine transporter, Tomography, Emission-Computed, Single-Photon, biology, medicine.diagnostic_test, business.industry, Dopaminergic, General Medicine, Guideline, PROGRESSIVE SUPRANUCLEAR PALSY, diagnostic imaging [Parkinsonian Disorders], LEWY BODIES, POINT-SPREAD FUNCTION, Molecular Imaging, biology.protein, TRANSPORTER AVAILABILITY, WHOLE-BODY BIODISTRIBUTION, Molecular imaging, DIFFERENTIAL-DIAGNOSIS, Nuclear Medicine, business

وصف الملف: Print-Electronic; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8259c59147589f43299ae9e734de6b20Test
https://lirias.kuleuven.be/handle/123456789/654920Test

10

The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study

المؤلفون: Morten Gersel Stokholm, Rola Ismail, Simon Fristed Eskildsen, Hanne Gottrup, Allan K Hansen, Kim V. Hansen, David J. Brooks, Peter Parbo, Pernille L. Kjeldsen, Lasse Stensvig Madsen, Jeppe L. Schaldemose

المصدر: Ismail, R, Parbo, P, Madsen, L S, Hansen, A K, Hansen, K V, Schaldemose, J L, Kjeldsen, P L, Stokholm, M G, Gottrup, H, Eskildsen, S F & Brooks, D J 2020, ' The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease : a longitudinal PET study ', Journal of Neuroinflammation, vol. 17, no. 1, 151 . https://doi.org/10.1186/s12974-020-01820-6Test
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Journal of Neuroinflammation

مصطلحات موضوعية: Male, 0301 basic medicine, MILD COGNITIVE IMPAIRMENT, Longitudinal study, Neurology, lcsh:RC346-429, 0302 clinical medicine, Neuroinflammation, Longitudinal Studies, BRAIN, TANGLES, Flortaucipir, medicine.diagnostic_test, Microglia, β-amyloid, General Neuroscience, beta-amyloid, Neurofibrillary Tangles, medicine.anatomical_structure, Positron emission tomography, Disease Progression, Cardiology, Female, medicine.symptom, MRI, PLAQUES, EXTRACTION, medicine.medical_specialty, Amyloid, PiB, Immunology, Prodromal Symptoms, tau Proteins, Inflammation, 03 medical and health sciences, Cellular and Molecular Neuroscience, POSITRON-EMISSION-TOMOGRAPHY, Alzheimer Disease, Internal medicine, Image Interpretation, Computer-Assisted, mental disorders, medicine, Humans, Cognitive Dysfunction, LOAD, Beta (finance), lcsh:Neurology. Diseases of the nervous system, Aged, PK11195, Amyloid beta-Peptides, business.industry, Research, MICROGLIAL ACTIVATION, MCI, PET, 030104 developmental biology, Positron-Emission Tomography, Alzheimer, Tau, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ed1916f133e151218ab5c6f47575b0Test
https://doi.org/10.1186/s12974-020-01820-6Test

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